Fitzsimons Innovation Campus Where business & science come together to develop innovative technologies that will change the future of healthcare

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1 Fitzsimns Innvatin Campus Where business & science cme tgether t develp innvative technlgies that will change the future f healthcare

2 Army Base Redevelpment then When Fitzsimns Clsed: 4,000 Jbs Lst Aging Neighbrhd 283 Buildings (85%> 30 years ld) Usable but Limited Infrastructure 3 Landfills Asbests

3 Innvatin Hub! nw Patient Care Educatin Biscience Research & Develpment Cmmercializatin Ecnmic Develpment

4 Fitzsimns Innvatin Campus & Anschutz Medical Campus Fitzsimns Innvatin Campus 150 acres Anschutz Medical Campus 217 acres Multi-tenant buildings that accmmdate Educatin Amenities Business Incubatr (pre-built labs, executive ffices suites, shared cnference rms and equipment ideal fr start up cmpanies) Acceleratr (custm built-t-suit space fr mre mature cmpanies) Opprtunity fr single tenant buildings and land sales 21 Fitzsimns (residential/retail twn center) Light rail statin ready fr riders in 2016 Fitness Center (Anschutz Health & Wellness Center) Child Develpment Center (perated by Children s Hspital) Clinical Research Schls f Medicine, Dentistry, Nursing, Pharmacy and Graduate Schl f Public Health Medical Library University Hspital s Out Patient and In Patient Pavilins, reginal Cancer Center, CeDAR 80 Cre Labs with available access t cmmercial cmpanies lcated in the Innvatin Campus 2 Research Twers Nighthrse Campbell distance medicine Barbara Davis Center fr Juvenile Diabetes Multiple restaurants and ther retail establishments

5 Key Resurces fr Start-Ups Virtual Physical + Office space + Cnference rms + Lab space Flexibility is key Advisry + Scientific review + Strategy + Materials + Fundraising + Partnering Services + Research + Manufacturing + Clinical trials Persnnel + Research + Regulatry + Management Other resurces

6 Biscience Park Center Incubatr & Acceleratr Wrld-class business develpment and supprt services t nsite clients and virtual clients 97,000 sf f state-f-the-art R&D, ffice and lab space Resurces, cntacts and netwrking pprtunities Industry wrkshps and training prgrams Investr Cnnectins Access t CU Anschutz Medical Campus Cre Labs Access t industry experts and service prviders

7 Charles C. Gates Bimanufacturing Facility Services include: Cell Therapy Manufacturing Prcess Develpment Scale up Manufacturing f bth cell therapyand prtein-based prducts, t cgmp standards Prcess dcumentatin Services are prvided t: Academic researchers Clinicians Early stage bitechnlgy cmpanies Five ISO7-grade cell prcessing suites that perate at 20 t 60 air changes per hur with singlepass, HEPA-filtered air supplied by a dedicated air-handling unit. Each suite is equipped with ne r tw bilgical safety cabinets, tabletp centrifuge, multiple HEPA-filtered tissue culture incubatrs, and ther specialized cell prcessing instruments.

8 Charles C. Gates Bimanufacturing Facility Prtein Manufacturing Crygenic and Material Strage Fur ISO7- and ISO8-grade manufacturing suites that perate at 20 t 40 air changes per hur with single-pass, HEPA-filtered air supplied by a dedicated airhandling unit. Suites are dedicated and equipped fr buffer preparatin, micrbial fermentatin (maximum vessel wrking vlume f 50 liters) and clarificatin, prtein purificatin, and aseptic frmulatin and fill f prduct. Material strage areas are equipped t stre materials at ambient r temperature-cntrlled cnditins. Crygenic strage rm is equipped with ultra-lw (-80 C) freezers, cntrlledrate crypreservatin freezers, and liquid nitrgen vapr strage freezers. Quality Cntrl Labratry State-f-the-art analytical equipment fr sterility, mycplasma and endtxin testing, envirnmental mnitring, and characterizatin f cell therapy and prtein prducts.

9 Charles C. Gates Bimanufacturing Facility Lcated n 3 rd flr f the Biscience Park Center at Fitz Fr mre infrmatin abut use f the Gates Center, cntact: Thmas Payne Ph.D, Directr f Cell Therapies - thmas.payne@ucdenver.edu Patrick Gaines, Business Develpment - patrick.gaines@ucdenver.edu Timthy Gardner, Business Develpment - timthy.gardner@ucdenver.edu

10 Innvatin Campus Prgrams There are prgrams and facilities designed t meet the needs f scientific cmpanies in every phase f their grwth, including: Virtual Client Prgram Use f Address & Cnference Rms $150/mnth Executive Office Suites Prgram Furnished ffices varying in sizes frm 1persn t 5 peple Mnth-t-mnth space agreements available Lab Space Prgram Built ut lab spaces that include fumehds, benches & ffices Scientific equipment available t share r fr exclusive use (at n additinal cst) 1-year space agreements that can be renewed Acceleratr Prgram Custm built space t yur specificatins There is plenty f free parking and the availability t mve arund the facilities t meet yur cmpany grwth requirements.

11 Incubatr Clients 60,000 sf Pre-built ffice/lab suites Executive suite services Advisry supprt Scientific equipment available t cmpanies Phne/data services Market rental rates Shrt-term space agreements

12 Biscience Park Center - Acceleratr 37,000 Square Feet $8.4 Millin Cnstructin Cmpleted the summer Incubatr Graduates have Expanded int Acceleratr Custm built-t-suit lab & ffice space Access t incubatr shared services and amenities

13 Biscience 2 New 4-stry 112,000 Square Feet University Research & Biengineering Prgram Cmmercial biscience cmpanies Ready fr ccupancy 2015 Custm built-t-suit lab & ffice space

14 Current Status f Cmpanies 43 Cmpanies currently lcated in Biscience Park Center and Biscience East buildings Therapeutics Medical Device Diagnstics Tl & Supprt Healthcare IT Over 600 jbs created t date $800 millin raised t date (btstrapped, grants, Angel investrs & Venture Capital)

15 Why Fitzsimns Innvatin Campus? Leverage pprtunity in Anschutz Medical Campus and Fitzsimns Life Science District Tier 1 Research University Access t University Cre Labs and Faculty 19,000+ life-science prfessinals emplyed tday Site grwing t 42,000+ life science prfessinals Ultimately 150 acres dedicated t supprting scientific innvatin & cmmercializatin 20 minutes t DIA and Dwntwn Denver ; with light rail cming in 2016

16 Questins? Fr mre infrmatin, visit r cntact Vicki Jenings t schedule a tur: vjenings@clbi.cm; Als be sure t check ut a vide that illustrates the exciting visin f the Fitzsimns Life Science District at Thanks!

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