e-media Kit GET CONNECTED TO THE INDUSTRY'S MOST HIGHLY-DESIRED AUDIENCE

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1 e-media Kit GET CONNECTED TO THE INDUSTRY'S MOST HIGHLY-DESIRED AUDIENCE

2 Contents Electronic Suite of Opportunities Usage Profile Website Advertising vlink: Web Video Ads e-issue Alert e-solution Broadcast Podcasts Webcasts Online Rate Card Contact Information

3 Usage Profile Applied Clinical Trial s e-audience Applied Clinical Trials (ACT) is the leading global information resource for clinical trials professionals. ACT s electronic audience is the most highly-desired professionals in today s marketplace comprised of magazine readers and professionals who have requested to receive information and e-newsletters from Applied Clinical Trials and Advanstar Communications. ACT attracts a global audience of mid to senior level professionals involved in pharmaceutical, contract research organizations (CRO), laboratory, regulatory, clinical research and academic organizations. Demographic Profile Representation BUSINESS AND INDUSTRY Pharmaceutical/BioPharmaceutical/Biologics % Contract Research Organization % Clinical Study Investigative Site % JOB FUNCTIONS R&D / PROJECT MANAGEMENT CLINICAL TRIALS MANAGEMENT CLINICAL RESEARCH ASSOCIATE/COORDINATOR CLINICAL TRIALS/GCP AUDITING/QA/QC CORPORATE MANAGEMENT Usage Profile ACTMAGAZINE.COM WEBSITE Unique Visitors 12,680* Vs. same period % Total Page Views 64,460* Vs. same period % *Leads among websites specializing in clinical trials - Alexa.com Traffic Ratings Average Time Spent on Site 7.8 min. e-issue ALERT Number of Subscribers 20,850 + Open Rate 24% + *3 month average (Oct, Nov, Dec 2006) + 2 month average (Nov, Dec 2006) 28% 23% 18% 8% 7%

4 THE SITE CLINICALLY PROVEN TO WORK Meet our worldwide audience of clinical trials professionals online. ACTmagazine.com enables you to drive target prospects from our community to yours with a simple click. Viewers frequently visit the site for access to technology updates, current product releases, latest FDA news, articles and other critical information applicable for managing clinical trials. Clinical trials professionals log on here for relevant information that can be immediately applied to their work. Website Advertising Opportunities Leaderboard x 90 Banner x 60 Skyscraper x 600 Big Box Ad x 280 (big box ads may be embedded into article pages) Build-A-Banner Ad Design Services You don't have the artwork ready but want immediate placement in our e-newsletter and website? Your solution is here. Our creative services team is ready to assist you in creating a dynamic online ad that will communicate your message in a convincing and professional manner. Speak with your sales representative for more details Coming Soon in September 2007! New advertising opportunities will be available on that position your message to a targeted audience via new category channels.

5 vlink Go Beyond the Clutter with Online Web Videos Improve recall of your web messages with an online video that dynamically presents your company and services in a highly effective medium. Web videos are at least 2.5x more effective than static internet ads at every step of the purchase cycle. Affordable, Easy, and Convey Leader Status Just provide us with the materials from your print ad, banners or video footage and we'll transform them into professional quality web videos. vlink pricing is a fraction of industry production and media costs for video and rich media content creation. Select from two ways to market your vlink web videos 24/7 on ACTmagazine.com: vlink Banner Make it simple: Super-charge your current banner ad. Prospects will click a camera icon placed within your banner to view your company profile, product or service video. Featured Sponsor Package Command the attention of your prospects: present your company s full range of capabilities with web videos on an Interactive Video Player positioned prominently on ACTmagazine.com. Included will be an exclusive branded hosted microsite, linked from our main navigation, that replays your videos and allows direct connection to your website, phone center and contacts. Video AD Reports All vlink web videos include a granular tracking report of clickthroughs on available links and video viewer frequency (how many times your video was viewed). *Ask your representative for more details on participating in special online programs tied to print and trade events. You may request additional marketing elements at cost.

6 e-issue Alert ACTion Issue Alert - Preview to the Print Edition Applied Clinical Trials monthly electronic issue alerts are deployed to approximately 20,850 readers as an adjunct to the monthly print edition. Included in the electronic ACTion Issue Alert are current feature articles, columns, on-line reader polls, and a "look ahead" at the next issue. The alert also features upcoming industry events both in the US and abroad. Viewers and readers receive this monthly alert free. E-Newsletter Advertising Opportunities Banner Positions: x 60 (primary, secondary, anchor) Skyscraper: x 600 Text Ad Positions:..65 words of content including live URL (positons available: primary, secondary or anchor)

7 e-solution Broadcast DESKTOP DELIVERY: YOUR MESSAGE TO OUR AUDIENCE You provide the message; we deliver it to the right audience. Your customized HTML and text formatted message including live hyperlinks, company logo, designated image, description and contact information delivered to the industry s most highly desired audience under the brand name of Applied Clinical Trials. Your message will be embedded into Applied Clinical Trials e-solution template and will deploy to selects you have chosen from our subscriber base. The e-solution Broadcast is a focused medium that drives our audience to your Website and provides the visibility necessary to turn interest to your company s capabilities. The e-solution broadcast is ideal for communicating: New product releases New acquisitions and company expansion Case study success stories Online Product Catalog Launch of new website Any marketing initiative that requires immediate attention from the right audience Offering Includes design and execution of e-solution Broadcast One round of edits from sponsor Minimum demographic selection of 3,500 subscribers

8 The most highly-trusted information provider just introduced a new way to keep clinical trials professionals in the know. Applied Clinical Trials editorial team proudly presents an editorially-driven podcast series designed to keep busy executives pulse on the industry. Via the audio podcasts, our editors will bring the issues and experts to the forefront in a quick and concise format ensuring that professionals involved with R&D, project management, clinical trials & project management, regulatory affairs, data management and others managing clinical trials spend their time in the most effective manner. The podcast may be downloaded for any MP3 player, desktop computer or other audio device ensuring our listeners don t miss a beat. Podcasts Editorial-driven podcasts are sure to generate interest and downloads from our viewers and listeners. Suggested Podcast Topics The Need for Speed e-media Kit Rejuvenating Subject Recruitment Predicting Protocol Success Two Sponsorship Options: Select from our Suggested Topics and Sponsor Choose a topic from our podcast calendar that is most relevant to your business solution. It s completely turnkey. Customize Your Sponsorship You have the topic; we have the audience! You can invite an editor or a third party to moderate the podcast while your team collaborates to secure the speakers and coordinate recording logistics. Benefits and Features of Sponsorship for either Opportunity 12 months of hosting in the Applied Clinical Trials Podcast Directory Sponsor logo positioned on the podcast download page Moderator will include a 30 to 60 second sponsor review during podcast intro Monthly metric report provided including # of downloads and site visits. Regaining the Public Trust Going Electronic: Tips on Using ectd This is a suggested list of topics and are subject to change. You may submit your own topic for sponsorship, but it will be subject to the approval of the Editor-inchief of Applied Clinical Trials. Suggested length of podcast is 10 minutes maximum. Marketing Element The series will be promoted through Applied Clinical Trials print magazine, e-newsletter, e-issue alerts and website to drive awareness of the podcast. Viewers are invited to subscribe to a free RSS feed, which sends notifications of new podcasts postings. Custom marketing proposals for your sponsored Podcast are available upon request.

9 Webcasts ACCELERATE YOUR BUSINESS WITH A COMPELLING MARKETING PROGRAM CONDUCTED BY THE EXPERTS Webcast Program Combining the immediacy and the impact of cutting-edge, interactive, web technologies, Applied Clinical Trials superb quality Webcast program strategically showcases your company as significant industry leader. The interactive webcast platform offers a compelling promotional outlet for sponsors that accelerates lead generation and produces actionable results while delivering educational information to our readers and viewers. Each Webcast is designed to generate new sales opportunities for participating sponsors by providing an educational forum for viewers to learn about new technologies and services, industry issues and solutions that will enable intuitive buying choices for their companies. Webcast Platform A complete turnkey marketing program that afford 60 to 70 minute video and/or audio Webcast broadcast live and/or on-demand. Package includes program management, marketing, production and execution by a trained professional staff. The most striking feature of the Webcast platform is the lead reporting functionality that allows for customized registrant profiling for successful qualification and following up of leads. Advanstar collaborates with an array of technology partners to ensure that your program is fully-serviced with the best technology that meets your program s needs. Webcast platform features 12 months on-demand viewing, master event CD, live question & answer, real-time polling, post-webcast survey deployment and real-time reporting functionality. Content Content is king! Advanstar Pharmaceutical & Science Group is comprised of the market s leading magazines spearheaded by the industry s leading editorial team. Our successful Webcast program is a direct result of the concerted effort to deliver programs that are editorially-driven and appealing to our readers based on our market expertise. As the sponsor you have the opportunity to collaborate with the editorial team of Applied Clinical Trials to refine your topic or seek new topics that complement your industry solution. A senior editor from the magazine will be available to moderate the Webcast at your request. Project Management The above responsibilities will be managed and executed, in cooperation with the sponsor, by Applied Clinical Trials team. A Webcast team leader will be assigned oversee the execution of marketing, content and operation project timelines and keep the Sponsor informed on the various event development stages. Preferred lead time for premium marketing results is 90 days prior to live broadcast.

10 Webcasts TARGET AND ENGAGE AN ACTIVE AND QUALIFIED AUDIENCE Marketing An aggressive, targeted, integrated marketing campaign leveraging the extensive reach of Advanstar s Pharmaceutical & Science Group successfully formulated to drive your brand s visibility and a qualified audience for your Webcast program. Our Webcast marketing program has been developed through years of trial and error to arrive at a formula that can generate the leads you want to have. Two pre-determined marketing platforms are available with diverse Webcast packages(see below). Custom marketing campaigns are available upon request. Standard Webcast Marketing Platform includes: 1 full-page print ad; 4 custom HTML/Text s; and two months of banners (or other available position) on the website and e-newsletter Premier Webcast Marketing Platform includes: 4 full page print ads; 6 custom HTML/Text formatted s; 3 months of banners (or other available position) on the website and e-newsletter Registration Management A flexible registration process enables profiling and qualification of your leads at the point of entry on a custom registration site. The sponsor will be invited to supply custom demographic questions to supplement the request for the registrant s contact information. Registration reports feature full audit of each attendee s activity both live and on-demand, real-time polling and post-event survey responses all designed to help further lead qualification. As a sponsor you will have unlimited use of the leads database and also may be downloaded into excel format which is conveniently accessible 24/7 beginning when your registration site is posted through close of on-demand viewing. Investment Two pre-determined packages are currently available. Audio Webcast Includes audio-only Webcast with live Q&A, real-time polling, 24/7 registration management, project management, standard marketing campaign, and editorial contribution Video Webcast Includes video Webcast broadcast live from a professional TV studio; Webcast features live Q&A, real-time polling, 24/7 registration management, project management, premium marketing campaign, and editorial contribution Additional marketing opportunities that transcend your online event to print are available with custom proposals upon request.

11 Online Rate Card WEB BANNER AD* SIZE RATE (per month) Banner 468x60 $1,250 Leaderboard 728x90 $1,700 Skyscraper 160x600 $2,500 Big Box* 336x280 $3,000 Button 120x60 $750 Positions available for above ads: Run of Site Home Page Article Pages* (Big Box Ads) Category Pages (coming in 2007) * Website banner ad rates do not include exclusive position VLINK WEB VIDEO AD VLINK BANNER FEATURED SPONSOR PACKAGE^ Includes integration of company profile video onto Interactive Video Cost to produce & add each product and service video to Interactive Video Banner PRODUCE + LINK TO PRODUCE + LINK TO COMPANY Banner & Development of exclusive and microsite. PRODUCT & SERVICE VIDEO^ PROFILE VIDEO^ microsite. Run Length: 3 months $450 + banner ad cost $950 + Banner Ad Charge $3,350 $450 each product & service video Run Length: 6 months $650 + banner ad cost $1,250 + Banner Ad Charge $5,350 $650 each Run Length: 12 months $1,150 + banner ad cost $1,850 + Banner Ad Charge $7,350 $1,150 each ^ PRODUCT & SERVICE VIDEO CHANGE FEES Video and text on player, host pages & rotating banners: $150 Developing additional new videos (not including hosting): $350 Custom quotes are available for video purchases in other multimedia formats. ^ COMPANY PROFILE VIDEO CHANGE FEES Changes beyond 1 st free proof to video and text on player, host pages & interactive banner: $250 Developing additional new videos (not including hosting) - $850 *Includes listing in up to 3 categories; additional categories are an additional charge. Custom quote for exclusive IVB based on design, production costs and website placement. ACTion e-issue ALERT SIZE RATE (per month) Banner 468x60 $1,000 Skyscraper 160x600 $1,000 Text Ads 65 word description with live hyperlink $750 E-SOLUTION BROADCAST to Digital Audience RATE $3,500 for a targeted audience of 5,000 $500/additional targeted audience of 1,000 WEBCAST Strategic Business Topic RATE $30,000 basic $40,000 premium PODCAST RATE Timely Trends and Industry Topic Audio Only: $3,500 All rates are net terms.

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