Proteins. Proteins. Amino Acids. Most diverse and most important molecule in. Functions: Functions (cont d)

Save this PDF as:
 WORD  PNG  TXT  JPG

Size: px
Start display at page:

Download "Proteins. Proteins. Amino Acids. Most diverse and most important molecule in. Functions: Functions (cont d)"

Transcription

1 Proteins Proteins Most diverse and most important molecule in living i organisms Functions: 1. Structural (keratin in hair, collagen in ligaments) 2. Storage (casein in mother s milk) 3. Transport (HAEMOGLOBIN!) 4. Hormonal (insulin) Proteins Functions (cont d) 5. Receptors (taste buds) 6. Contractile (actin in muscles) 7. Defensive (fibrin for clotting) 8. Enzymatic (lactase) (sophisticated) structure determines function Has its own unique 3D shape/conformation Simplest protein = polymer of amino acids (polypeptides) Amino Acids Amphiprotic (posses both acidic, carboxyl, and basic, amino groups). May be polar, nonpolar or charged depending on the R group Sequence determines the final shape (conformation) of protein. 1

2 Building proteins Polypeptide chains N-terminus = NH 2 end C-terminus = COOH end repeated sequence (N-C-C) is the polypeptide backbone can only grow in one direction Amino Acids There are 20 different R groups, thus different a.a. (amino acids) Of the 20 amino acids that make up proteins, we must consume 8, as we can not make these essential amino acids on our own: trp, met, val, thre, phe, leu, ile, lys. PolypeptideChain Ranges from a few amino acids Amino acids are joined together by peptide bonds (amide bonds) Condensation reaction between amino group and carboxyl group of adjacent amino acid 2

3 Nonpolar amino acids - nonpolar & hydrophobic Polar amino acids - polar or charged & hydrophilic Why are these nonpolar & hydrophobic? Why are these polar & hydrophillic? The Four Levels of Protein Folding Primary Structure: The sequence of amino acids in a polypeptide chain, which is determined by the nucleotide sequence of a particular gene. 3

4 The Four Levels of Protein Folding Secondary Structure: The folding and coiling of the polypeptide chain as it grows into a pleated sheet or helix H bond between C=O group and N-H group every 4 th amino acid to form alpha helix. When 2 parts of the chain lie parallel l forms a beta pleated sheet The Four Levels of Protein Folding Tertiary Structure: The polypeptide chain undergoes additional folding due to side chain interactions. Hydrophobic interaction hydrophobic regions direct themselves into core of protein Hydrogen bonds between polar R grps Ionic bonds - between (+) and (-) charged R grps Disulphide bridges- STRONG covalent bonds between 2 sulfhydryl grps (from cysteine monomers) Quaternary Structure: Two or more polypeptide chains come together, such as in collagen and haemoglobin. Chaperonin proteins Guide protein folding provide shelter for folding polypeptides keep the new protein segregated from cytoplasmic influences 4

5 Protein unfolding Temperature, salinity and ph changes can cause a protein to unravel (denature). A denatured d protein is unable to carry out its biological function. Protein denaturation Uses include: 1. meats cured by denaturing spoilage bacteria 2. Blanching fruits denatures browning enzymes 3. Temporarily curl/straighten hair (w/ heat) 4. Meats easier to chew when heat is used to denature fibrous fb proteins Protein structure (review) Nucleic Acids 1 aa sequence peptide bonds determined by DNA 2 R groups H bonds 3 R groups hydrophobic interactions, disulfide bridges 4 multiple polypeptides hydrophobic interactions Nucleic acids are found in DNA (stores hereditary info.), RNA (ribonucleic acid), ATP and nucleotide coenzymes (NAD +, NADP + and FAD) used in energy transformations. DNA and RNA are nucleotide polymers. Nucleotides consist of a nitrogenous base, a fivecarbon sugar and a phosphate group. The nitrogenous bases are: adenine (A), guanine (G), cytosine (C), thymine (T) and uracil (U). 5

6 Nucleic Acids Cytosine, thymine and uracil are single-ringed pyramidines,, while adenine and guanine are larger double-ringed purines. In DNA, A bonds with T with 2 hydrogen bonds, and G bonds with C with 3 hydrogen bonds. The two strands are antiparallel (one strand is upside down compared to the other). Purines always bond with a pyramidine. Building the polymer 6

7 Nucleic polymer Backbone sugar to PO 4 bond phosphodiester bond new base added to sugar of previous base polymer grows in one direction N bases hang off the sugar-phosphate backbone Information polymer Function series of bases encodes information like the letters of a book stored information is passed from parent to offspring need to copy accurately stored information = genes genetic information Dangling bases? Why is this important? Passing on information? Why is this important? Interesting note ATP Adenosine triphosphate modified nucleotide adenine (AMP) + P i + P i + + 7

Proteins and Nucleic Acids

Proteins and Nucleic Acids Proteins and Nucleic Acids Chapter 5 Macromolecules: Proteins Proteins Most structurally & functionally diverse group of biomolecules. : o Involved in almost everything o Enzymes o Structure (keratin,

More information

Concept 5.4: Proteins include a diversity of structures, resulting in a wide range of functions

Concept 5.4: Proteins include a diversity of structures, resulting in a wide range of functions Concept 5.4: Proteins include a diversity of structures, resulting in a wide range of functions Proteins account for more than 50% of the dry mass of most cells Some proteins speed up chemical reactions

More information

8/20/2012 H C OH H R. Proteins

8/20/2012 H C OH H R. Proteins Proteins Rubisco monomer = amino acids 20 different amino acids polymer = polypeptide protein can be one or more polypeptide chains folded & bonded together large & complex 3-D shape hemoglobin Amino acids

More information

Chapter 5. The Structure and Function of Macromolecule s

Chapter 5. The Structure and Function of Macromolecule s Chapter 5 The Structure and Function of Macromolecule s Most Macromolecules are polymers: Polymer: (poly: many; mer: part) Large molecules consisting of many identical or similar subunits connected together.

More information

CHAPTER 3 THE CHEMISTRY OF ORGANIC MOLECULES

CHAPTER 3 THE CHEMISTRY OF ORGANIC MOLECULES CHAPTER 3 THE CHEMISTRY OF ORGANIC MOLECULES 3.1 Organic Molecules The chemistry of carbon accounts for the diversity of organic molecules found in living things. Carbon has six electrons, four of which

More information

A disaccharide is formed when a dehydration reaction joins two monosaccharides. This covalent bond is called a glycosidic linkage.

A disaccharide is formed when a dehydration reaction joins two monosaccharides. This covalent bond is called a glycosidic linkage. CH 5 Structure & Function of Large Molecules: Macromolecules Molecules of Life All living things are made up of four classes of large biological molecules: carbohydrates, lipids, proteins, and nucleic

More information

The Molecules of Cells

The Molecules of Cells The Molecules of Cells I. Introduction A. Most of the world s population cannot digest milk-based foods. 1. These people are lactose intolerant because they lack the enzyme lactase. 2. This illustrates

More information

Recap. Lecture 2. Protein conformation. Proteins. 8 types of protein function 10/21/10. Proteins.. > 50% dry weight of a cell

Recap. Lecture 2. Protein conformation. Proteins. 8 types of protein function 10/21/10. Proteins.. > 50% dry weight of a cell Lecture 2 Protein conformation ecap Proteins.. > 50% dry weight of a cell ell s building blocks and molecular tools. More important than genes A large variety of functions http://www.tcd.ie/biochemistry/courses/jf_lectures.php

More information

Biological Molecules

Biological Molecules Biological Molecules I won t lie. This is probably the most boring topic you have ever done in any science. It s pretty much as simple as this: learn the material deal with it. Enjoy don t say I didn t

More information

Molecules of Life. Chapter 3 Part 2

Molecules of Life. Chapter 3 Part 2 Molecules of Life Chapter 3 Part 2 3.5 Proteins Diversity in Structure and Function Proteins are the most diverse biological molecule (structural, nutritious, enzyme, transport, communication, and defense

More information

4. Which carbohydrate would you find as part of a molecule of RNA? a. Galactose b. Deoxyribose c. Ribose d. Glucose

4. Which carbohydrate would you find as part of a molecule of RNA? a. Galactose b. Deoxyribose c. Ribose d. Glucose 1. How is a polymer formed from multiple monomers? a. From the growth of the chain of carbon atoms b. By the removal of an OH group and a hydrogen atom c. By the addition of an OH group and a hydrogen

More information

Built from 20 kinds of amino acids

Built from 20 kinds of amino acids Built from 20 kinds of amino acids Each Protein has a three dimensional structure. Majority of proteins are compact. Highly convoluted molecules. Proteins are folded polypeptides. There are four levels

More information

the nature and importance of biomacromolecules in the chemistry of the cell: synthesis of biomacromolecules through the condensation reaction lipids

the nature and importance of biomacromolecules in the chemistry of the cell: synthesis of biomacromolecules through the condensation reaction lipids the nature and importance of biomacromolecules in the chemistry of the cell: synthesis of biomacromolecules through the condensation reaction lipids and their sub-units; the role of lipids in the plasma

More information

Lesson Overview. Carbon Compounds. Lesson Overview 2.3

Lesson Overview. Carbon Compounds. Lesson Overview 2.3 Lesson Overview 2.3 The Chemistry of Carbon Carbon atoms can form strong covalent bonds with many other elements. Molecules containing carbon are called organic. Living organisms are composed of molecules

More information

WEEK ONE VOCABULARY. Adhesion- the attraction between water molecules and other molecules

WEEK ONE VOCABULARY. Adhesion- the attraction between water molecules and other molecules WEEK ONE VOCABULARY Acid- hydrogen donors; acids increase the hydrogen ion concentration in solution Adhesion- the attraction between water molecules and other molecules Alpha (α) helix- secondary protein

More information

Chapter 3: Biological Molecules. 1. Carbohydrates 2. Lipids 3. Proteins 4. Nucleic Acids

Chapter 3: Biological Molecules. 1. Carbohydrates 2. Lipids 3. Proteins 4. Nucleic Acids Chapter 3: Biological Molecules 1. Carbohydrates 2. Lipids 3. Proteins 4. Nucleic Acids Elements in Biological Molecules Biological macromolecules are made almost entirely of just 6 elements: Carbon (C)

More information

Disaccharides consist of two monosaccharide monomers covalently linked by a glycosidic bond. They function in sugar transport.

Disaccharides consist of two monosaccharide monomers covalently linked by a glycosidic bond. They function in sugar transport. 1. The fundamental life processes of plants and animals depend on a variety of chemical reactions that occur in specialized areas of the organism s cells. As a basis for understanding this concept: 1.

More information

Biochemistry of Cells

Biochemistry of Cells Biochemistry of Cells 1 Carbon-based Molecules Although a cell is mostly water, the rest of the cell consists mostly of carbon-based molecules Organic chemistry is the study of carbon compounds Carbon

More information

Chapter 3 Molecules of Cells

Chapter 3 Molecules of Cells Bio 100 Molecules of cells 1 Chapter 3 Molecules of Cells Compounds containing carbon are called organic compounds Molecules such as methane that are only composed of carbon and hydrogen are called hydrocarbons

More information

The Structure and Function of Large Biological Molecules by Dr. Ty C.M. Hoffman

The Structure and Function of Large Biological Molecules by Dr. Ty C.M. Hoffman The Structure and Function of Large Biological Molecules by Dr. Ty C.M. Hoffman Slide 1 All of the biological macromolecules are built from smaller subunits. Each subunit features - H and - OH substituents

More information

Elements in Biological Molecules

Elements in Biological Molecules Chapter 3: Biological Molecules 1. Carbohydrates 2. Lipids 3. Proteins 4. Nucleic Acids Elements in Biological Molecules Biological macromolecules are made almost entirely of just 6 elements: Carbon (C)

More information

Biological molecules:

Biological molecules: Biological molecules: All are organic (based on carbon). Monomers vs. polymers: Monomers refer to the subunits that, when polymerized, make up a larger polymer. Monomers may function on their own in some

More information

http://faculty.sau.edu.sa/h.alshehri

http://faculty.sau.edu.sa/h.alshehri http://faculty.sau.edu.sa/h.alshehri Definition: Proteins are macromolecules with a backbone formed by polymerization of amino acids. Proteins carry out a number of functions in living organisms: - They

More information

Carbohydrates, proteins and lipids

Carbohydrates, proteins and lipids Carbohydrates, proteins and lipids Chapter 3 MACROMOLECULES Macromolecules: polymers with molecular weights >1,000 Functional groups THE FOUR MACROMOLECULES IN LIFE Molecules in living organisms: proteins,

More information

Chemical Level of Organization

Chemical Level of Organization Chemical Level of Organization Matter and Energy Matter occupies space and has mass Energy is capacity to move mass Potential vs. kinetic Energy forms radiant-moving waves electrical-moving charged particles

More information

IV. -Amino Acids: carboxyl and amino groups bonded to -Carbon. V. Polypeptides and Proteins

IV. -Amino Acids: carboxyl and amino groups bonded to -Carbon. V. Polypeptides and Proteins IV. -Amino Acids: carboxyl and amino groups bonded to -Carbon A. Acid/Base properties 1. carboxyl group is proton donor! weak acid 2. amino group is proton acceptor! weak base 3. At physiological ph: H

More information

Lecture Overview. Hydrogen Bonds. Special Properties of Water Molecules. Universal Solvent. ph Scale Illustrated. special properties of water

Lecture Overview. Hydrogen Bonds. Special Properties of Water Molecules. Universal Solvent. ph Scale Illustrated. special properties of water Lecture Overview special properties of water > water as a solvent > ph molecules of the cell > properties of carbon > carbohydrates > lipids > proteins > nucleic acids Hydrogen Bonds polarity of water

More information

Chapter 5: The Structure and Function of Large Biological Molecules

Chapter 5: The Structure and Function of Large Biological Molecules Name Period Chapter 5: The Structure and Function of Large Biological Molecules Concept 5.1 Macromolecules are polymers, built from monomers 1. The large molecules of all living things fall into just four

More information

Chemistry of Life - Part 2 Biological Molecules

Chemistry of Life - Part 2 Biological Molecules Chemistry of Life - Part 2 Biological Molecules 1 Of the 92 naturally occurring elements, 16 are known to be important constituents of living systems. The important elements are C, H, O, N, P, S, K, Ca,

More information

Genetic information (DNA) determines structure of proteins DNA RNA proteins cell structure 3.11 3.15 enzymes control cell chemistry ( metabolism )

Genetic information (DNA) determines structure of proteins DNA RNA proteins cell structure 3.11 3.15 enzymes control cell chemistry ( metabolism ) Biology 1406 Exam 3 Notes Structure of DNA Ch. 10 Genetic information (DNA) determines structure of proteins DNA RNA proteins cell structure 3.11 3.15 enzymes control cell chemistry ( metabolism ) Proteins

More information

Chapter 2 Chemical Principles

Chapter 2 Chemical Principles Chapter 2 Chemical Principles I. Chemistry. [Students should read this section on their own]. a. Chemistry is the study of the interactions between atoms and molecules. b. The atom is the smallest unit

More information

Chapter 5: The Structure and Function of Large Biological Molecules

Chapter 5: The Structure and Function of Large Biological Molecules Name Period Concept 5.1 Macromolecules are polymers, built from monomers 1. The large molecules of all living things fall into just four main classes. Name them. 2. Circle the three classes that are called

More information

1. In most animal cells, a complex network of proteins provides which of the following?

1. In most animal cells, a complex network of proteins provides which of the following? Organic Molecules and Water 1. In most animal cells, a complex network of proteins provides which of the following? A. organization B. shape C. movement D. all of these 2. Technology Enhanced Questions

More information

The Structure and Function of Large Biological Molecules

The Structure and Function of Large Biological Molecules Chapter 5 1 The Structure and Function of Large Biological Molecules PowerPoint Lecture Presentations for Biology Eighth Edition Neil Campbell and Jane Reece Lectures by Chris Romero, updated by Erin Barley

More information

NUCLEIC ACIDS. An INTRODUCTION. Two classes of Nucleic Acids

NUCLEIC ACIDS. An INTRODUCTION. Two classes of Nucleic Acids NUCLEIC ACIDS An INTRODUCTION Two classes of Nucleic Acids Deoxynucleic Acids (DNA) Hereditary molecule of all cellular life Stores genetic information (encodes) Transmits genetic information Information

More information

DNA is found in all organisms from the smallest bacteria to humans. DNA has the same composition and structure in all organisms!

DNA is found in all organisms from the smallest bacteria to humans. DNA has the same composition and structure in all organisms! Biological Sciences Initiative HHMI DNA omponents and Structure Introduction Nucleic acids are molecules that are essential to, and characteristic of, life on Earth. There are two basic types of nucleic

More information

A. A peptide with 12 amino acids has the following amino acid composition: 2 Met, 1 Tyr, 1 Trp, 2 Glu, 1 Lys, 1 Arg, 1 Thr, 1 Asn, 1 Ile, 1 Cys

A. A peptide with 12 amino acids has the following amino acid composition: 2 Met, 1 Tyr, 1 Trp, 2 Glu, 1 Lys, 1 Arg, 1 Thr, 1 Asn, 1 Ile, 1 Cys Questions- Proteins & Enzymes A. A peptide with 12 amino acids has the following amino acid composition: 2 Met, 1 Tyr, 1 Trp, 2 Glu, 1 Lys, 1 Arg, 1 Thr, 1 Asn, 1 Ile, 1 Cys Reaction of the intact peptide

More information

Pipe Cleaner Proteins. Essential question: How does the structure of proteins relate to their function in the cell?

Pipe Cleaner Proteins. Essential question: How does the structure of proteins relate to their function in the cell? Pipe Cleaner Proteins GPS: SB1 Students will analyze the nature of the relationships between structures and functions in living cells. Essential question: How does the structure of proteins relate to their

More information

BIOMOLECULES. reflect

BIOMOLECULES. reflect reflect A child s building blocks are relatively simple structures. When they come together, however, they can form magnifi cent structures. The elaborate city scene to the right is made of small, simple

More information

I. Polymers & Macromolecules Figure 1: Polymers. Polymer: Macromolecule: Figure 2: Dehydration Synthesis

I. Polymers & Macromolecules Figure 1: Polymers. Polymer: Macromolecule: Figure 2: Dehydration Synthesis I. Polymers & Macromolecules Figure 1: Polymers Polymer: Macromolecule: Figure 2: Dehydration Synthesis 1 Dehydration Synthesis: Figure 3: Hydrolysis Hydrolysis: II. Organic Macromolecules Class I: Carbohydrates:

More information

Shu-Ping Lin, Ph.D. E-mail: splin@dragon.nchu.edu.tw

Shu-Ping Lin, Ph.D. E-mail: splin@dragon.nchu.edu.tw Amino Acids & Proteins Shu-Ping Lin, Ph.D. Institute te of Biomedical Engineering ing E-mail: splin@dragon.nchu.edu.tw Website: http://web.nchu.edu.tw/pweb/users/splin/ edu tw/pweb/users/splin/ Date: 10.13.2010

More information

Protein Physics. A. V. Finkelstein & O. B. Ptitsyn LECTURE 1

Protein Physics. A. V. Finkelstein & O. B. Ptitsyn LECTURE 1 Protein Physics A. V. Finkelstein & O. B. Ptitsyn LECTURE 1 PROTEINS Functions in a Cell MOLECULAR MACHINES BUILDING BLOCKS of a CELL ARMS of a CELL ENZYMES - enzymatic catalysis of biochemical reactions

More information

Advanced Medicinal & Pharmaceutical Chemistry CHEM 5412 Dept. of Chemistry, TAMUK

Advanced Medicinal & Pharmaceutical Chemistry CHEM 5412 Dept. of Chemistry, TAMUK Advanced Medicinal & Pharmaceutical Chemistry CHEM 5412 Dept. of Chemistry, TAMUK Dai Lu, Ph.D. dlu@tamhsc.edu Tel: 361-221-0745 Office: RCOP, Room 307 Drug Discovery and Development Drug Molecules Medicinal

More information

Nucleotides and Nucleic Acids

Nucleotides and Nucleic Acids Nucleotides and Nucleic Acids Brief History 1 1869 - Miescher Isolated nuclein from soiled bandages 1902 - Garrod Studied rare genetic disorder: Alkaptonuria; concluded that specific gene is associated

More information

The Chapter Structure 5 and Function of Large Biological Molecules

The Chapter Structure 5 and Function of Large Biological Molecules Overview: The Molecules of Life The Chapter Structure 5 and Function of Large Biological Molecules The Structure and Function of Large Biological Molecules All living things are made up of four classes

More information

BIOLOGICAL MOLECULES OF LIFE

BIOLOGICAL MOLECULES OF LIFE BIOLOGICAL MOLECULES OF LIFE C A R B O H Y D R A T E S, L I P I D S, P R O T E I N S, A N D N U C L E I C A C I D S The Academic Support Center @ Daytona State College (Science 115, Page 1 of 29) Carbon

More information

Chapter 2 The Molecules of Cells

Chapter 2 The Molecules of Cells Chemistry is the science dealing with the properties & the transformations (chemical reactions) of all forms of matter Matter is any substance: solid, liquid, gas, plasma All matter is composed of elements

More information

2007 7.013 Problem Set 1 KEY

2007 7.013 Problem Set 1 KEY 2007 7.013 Problem Set 1 KEY Due before 5 PM on FRIDAY, February 16, 2007. Turn answers in to the box outside of 68-120. PLEASE WRITE YOUR ANSWERS ON THIS PRINTOUT. 1. Where in a eukaryotic cell do you

More information

18.2 Protein Structure and Function: An Overview

18.2 Protein Structure and Function: An Overview 18.2 Protein Structure and Function: An Overview Protein: A large biological molecule made of many amino acids linked together through peptide bonds. Alpha-amino acid: Compound with an amino group bonded

More information

Name Date Period. 2. When a molecule of double-stranded DNA undergoes replication, it results in

Name Date Period. 2. When a molecule of double-stranded DNA undergoes replication, it results in DNA, RNA, Protein Synthesis Keystone 1. During the process shown above, the two strands of one DNA molecule are unwound. Then, DNA polymerases add complementary nucleotides to each strand which results

More information

Chemistry Comes Alive: Part B

Chemistry Comes Alive: Part B 2 Chemistry Comes Alive: Part B Classes of Compounds Inorganic compounds Water, salts, and many acids and bases Do not contain carbon Organic compounds Carbohydrates, fats, proteins, and nucleic acids

More information

Amino Acids, Proteins, and Enzymes. Primary and Secondary Structure Tertiary and Quaternary Structure Protein Hydrolysis and Denaturation

Amino Acids, Proteins, and Enzymes. Primary and Secondary Structure Tertiary and Quaternary Structure Protein Hydrolysis and Denaturation Amino Acids, Proteins, and Enzymes Primary and Secondary Structure Tertiary and Quaternary Structure Protein Hydrolysis and Denaturation 1 Primary Structure of Proteins H 3 N The particular sequence of

More information

Structure of proteins

Structure of proteins Structure of proteins Primary structure: is amino acids sequence or the covalent structure (50-2500) amino acids M.Wt. of amino acid=110 Dalton (56 110=5610 Dalton). Single chain or more than one polypeptide

More information

DNA, RNA AND PROTEIN SYNTHESIS

DNA, RNA AND PROTEIN SYNTHESIS DNA, RNA AND PROTEIN SYNTHESIS Evolution of Eukaryotic Cells Eukaryotes are larger, more complex cells that contain a nucleus and membrane bound organelles. Oldest eukarytotic fossil is 1800 million years

More information

Dept.Anatomy Cytology / Lec 2-chmistry of cell Dr.sarsb

Dept.Anatomy Cytology / Lec 2-chmistry of cell Dr.sarsb Dept.Anatomy Cytology / Lec 2-chmistry of cell Dr.sarsb CHEMICAL ORGANIZATION OF CYTOSOL Chemically, the cytoplasmic matrix is composed of many chemical elements in the form of atoms, ions and molecules.

More information

Chapter 10: Protein Synthesis. Biology

Chapter 10: Protein Synthesis. Biology Chapter 10: Protein Synthesis Biology Let s Review What are proteins? Chains of amino acids Some are enzymes Some are structural components of cells and tissues More Review What are ribosomes? Cell structures

More information

2.1 Nucleic acids the molecules of life

2.1 Nucleic acids the molecules of life 1 2.1 Nucleic acids the molecules of life Nucleic acids information molecules of the cells form new cells stored in chromosomes in nucleus of the cell in the form of a code in DNA / parts of the code are

More information

Preliminary MFM Quiz

Preliminary MFM Quiz Preliminary MFM Quiz 1. The major carrier of chemical energy in all cells is: A) adenosine monophosphate B) adenosine diphosphate C) adenosine trisphosphate D) guanosine trisphosphate E) carbamoyl phosphate

More information

Biochemistry 2000 Sample Question Proteins. (1) Identify the secondary structure described in each of the following statements:

Biochemistry 2000 Sample Question Proteins. (1) Identify the secondary structure described in each of the following statements: (1) Identify the secondary structure described in each of the following statements: a. A coiled peptide chain held in place by hydrogen bonding between peptide bonds in the same chain b. A structure that

More information

Activity 4/5.1 How Can You Identify Organic Macromolecules?

Activity 4/5.1 How Can You Identify Organic Macromolecules? Answers? Activity 4/5.1 ow an You Identify rganic Macromolecules? efer to the figure (Some Simple hemistry) on the next page when doing this activity. Part A. Answer the questions. Then use your answers

More information

Lecture 26: Overview of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) structure

Lecture 26: Overview of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) structure Lecture 26: Overview of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) structure Nucleic acids play an important role in the storage and expression of genetic information. They are divided into

More information

I. Chapter 5 Summary. II. Nucleotides & Nucleic Acids. III. Lipids

I. Chapter 5 Summary. II. Nucleotides & Nucleic Acids. III. Lipids I. Chapter 5 Summary A. Simple Sugars (CH 2 O) n : 1. One C contains a carbonyl (C=O) rest contain - 2. Classification by functional group: aldoses & ketoses 3. Classification by number of C's: trioses,

More information

Part A: Amino Acids and Peptides (Is the peptide IAG the same as the peptide GAI?)

Part A: Amino Acids and Peptides (Is the peptide IAG the same as the peptide GAI?) ChemActivity 46 Amino Acids, Polypeptides and Proteins 1 ChemActivity 46 Part A: Amino Acids and Peptides (Is the peptide IAG the same as the peptide GAI?) Model 1: The 20 Amino Acids at Biological p See

More information

PRACTICE TEST QUESTIONS

PRACTICE TEST QUESTIONS PART A: MULTIPLE CHOICE QUESTIONS PRACTICE TEST QUESTIONS DNA & PROTEIN SYNTHESIS B 1. One of the functions of DNA is to A. secrete vacuoles. B. make copies of itself. C. join amino acids to each other.

More information

Life. In nature, we find living things and non living things. Living things can move, reproduce, as opposed to non living things.

Life. In nature, we find living things and non living things. Living things can move, reproduce, as opposed to non living things. Computat onal Biology Lecture 1 Life In nature, we find living things and non living things. Living things can move, reproduce, as opposed to non living things. Both are composed of the same atoms and

More information

Lab #5: DNA, RNA & Protein Synthesis. Heredity & Human Affairs (Biology 1605) Spring 2012

Lab #5: DNA, RNA & Protein Synthesis. Heredity & Human Affairs (Biology 1605) Spring 2012 Lab #5: DNA, RNA & Protein Synthesis Heredity & Human Affairs (Biology 1605) Spring 2012 DNA Stands for : Deoxyribonucleic Acid Double-stranded helix Made up of nucleotides Each nucleotide= 1. 5-carbon

More information

Name: Hour: Elements & Macromolecules in Organisms

Name: Hour: Elements & Macromolecules in Organisms Name: Hour: Elements & Macromolecules in Organisms Most common elements in living things are carbon, hydrogen, nitrogen, and oxygen. These four elements constitute about 95% of your body weight. All compounds

More information

2. True or False? The sequence of nucleotides in the human genome is 90.9% identical from one person to the next. False (it s 99.

2. True or False? The sequence of nucleotides in the human genome is 90.9% identical from one person to the next. False (it s 99. 1. True or False? A typical chromosome can contain several hundred to several thousand genes, arranged in linear order along the DNA molecule present in the chromosome. True 2. True or False? The sequence

More information

Carbon-organic Compounds

Carbon-organic Compounds Elements in Cells The living substance of cells is made up of cytoplasm and the structures within it. About 96% of cytoplasm and its included structures are composed of the elements carbon, hydrogen, oxygen,

More information

Amino Acids. Amino acids are the building blocks of proteins. All AA s have the same basic structure: Side Chain. Alpha Carbon. Carboxyl. Group.

Amino Acids. Amino acids are the building blocks of proteins. All AA s have the same basic structure: Side Chain. Alpha Carbon. Carboxyl. Group. Protein Structure Amino Acids Amino acids are the building blocks of proteins. All AA s have the same basic structure: Side Chain Alpha Carbon Amino Group Carboxyl Group Amino Acid Properties There are

More information

1. Which of the following correctly organizes genetic material from the broadest category to the most specific category?

1. Which of the following correctly organizes genetic material from the broadest category to the most specific category? DNA and Genetics 1. Which of the following correctly organizes genetic material from the broadest category to the most specific category? A. genome chromosome gene DNA molecule B. genome chromosome DNA

More information

Chapter 19 Amino Acids and Proteins

Chapter 19 Amino Acids and Proteins Chapter 19 Amino Acids and Proteins 19.1 Proteins and Amino Acids 19.2 Amino Acids as Acids and Bases Copyright 2007 by Pearson Education, Inc. Publishing as Benjamin Cummings 1 Functions of Proteins Proteins

More information

Sickle cell anemia: Altered beta chain Single AA change (#6 Glu to Val) Consequence: Protein polymerizes Change in RBC shape ---> phenotypes

Sickle cell anemia: Altered beta chain Single AA change (#6 Glu to Val) Consequence: Protein polymerizes Change in RBC shape ---> phenotypes Protein Structure Polypeptide: Protein: Therefore: Example: Single chain of amino acids 1 or more polypeptide chains All polypeptides are proteins Some proteins contain >1 polypeptide Hemoglobin (O 2 binding

More information

Helices From Readily in Biological Structures

Helices From Readily in Biological Structures The α Helix and the β Sheet Are Common Folding Patterns Although the overall conformation each protein is unique, there are only two different folding patterns are present in all proteins, which are α

More information

The Chemical Basis of Life. Chemical Bonds

The Chemical Basis of Life. Chemical Bonds The Chemical Basis of Life white=hydrogen red=oxygen gray=carbon yellow=phosphorus blue=nitrogen green=sulfur All organisms are made up of water, inorganic ions, small molecules (77% by weight) and macromolecules

More information

Section 1 Workbook (unit 2) ANSWERS

Section 1 Workbook (unit 2) ANSWERS Section 1 Workbook (unit 2) ANSWERS Complete the following table: nucleotide DNA RN Name: B5. Describe DNA replication 1) Label each base given in the diagram below and describe the 4 primary characteristics

More information

Nucleic Acids: DNA and RNA

Nucleic Acids: DNA and RNA Nucleic Acids: DNA and RNA Nucleic Acids Responsible for the transfer of genetic information. Two forms of nucleic acids: Ribonucleic Acid (RNA) Mainly found in cytoplasm Deoxyribonucleic Acid (DNA) Found

More information

Ch. 12: DNA and RNA 12.1 DNA Chromosomes and DNA Replication

Ch. 12: DNA and RNA 12.1 DNA Chromosomes and DNA Replication Ch. 12: DNA and RNA 12.1 DNA A. To understand genetics, biologists had to learn the chemical makeup of the gene Genes are made of DNA DNA stores and transmits the genetic information from one generation

More information

AP BIOLOGY 2008 SCORING GUIDELINES

AP BIOLOGY 2008 SCORING GUIDELINES AP BIOLOGY 2008 SCORING GUIDELINES Question 1 1. The physical structure of a protein often reflects and affects its function. (a) Describe THREE types of chemical bonds/interactions found in proteins.

More information

STRUCTURES OF NUCLEIC ACIDS

STRUCTURES OF NUCLEIC ACIDS CHAPTER 2 STRUCTURES OF NUCLEIC ACIDS What is the chemical structure of a deoxyribonucleic acid (DNA) molecule? DNA is a polymer of deoxyribonucleotides. All nucleic acids consist of nucleotides as building

More information

Structure and properties of proteins. Vladimíra Kvasnicová

Structure and properties of proteins. Vladimíra Kvasnicová Structure and properties of proteins Vladimíra Kvasnicová Chemical nature of proteins biopolymers of amino acids macromolecules (M r > 10 000) Classification of proteins 1) by localization in an organism

More information

Replication Study Guide

Replication Study Guide Replication Study Guide This study guide is a written version of the material you have seen presented in the replication unit. Self-reproduction is a function of life that human-engineered systems have

More information

Solution key Problem Set 1

Solution key Problem Set 1 Solution key-7.016 Problem Set 1 Question 1 The following line-angle drawings represent three chemical structures. On each drawing, the hydrogen atoms that should be bonded to the NON-carbon atoms are

More information

Unit 1: Chemistry of Life Guided Reading Questions (70 pts total)

Unit 1: Chemistry of Life Guided Reading Questions (70 pts total) AP Biology Biology, Campbell and Reece, 10th Edition Adapted from chapter reading guides originally created by Lynn Miriello Name: Unit 1: Chemistry of Life Guided Reading Questions (70 pts total) Chapter

More information

1. 1. Amino acids and proteins. 1: Biochemistry of macromolecules and metabolic pathways. Key terms

1. 1. Amino acids and proteins. 1: Biochemistry of macromolecules and metabolic pathways. Key terms 1. 1 Amino acids and proteins Key terms Polymer: A large molecule made from repeating units called monomers. Monomer: A molecule that is a basic unit; many monomers join together to make a polymer. Amino

More information

OUTCOMES. PROTEIN SYNTHESIS IB Biology Core Topic 3.5 Transcription and Translation OVERVIEW ANIMATION CONTEXT RIBONUCLEIC ACID (RNA)

OUTCOMES. PROTEIN SYNTHESIS IB Biology Core Topic 3.5 Transcription and Translation OVERVIEW ANIMATION CONTEXT RIBONUCLEIC ACID (RNA) OUTCOMES PROTEIN SYNTHESIS IB Biology Core Topic 3.5 Transcription and Translation 3.5.1 Compare the structure of RNA and DNA. 3.5.2 Outline DNA transcription in terms of the formation of an RNA strand

More information

Worked solutions to student book questions Chapter 13 DNA

Worked solutions to student book questions Chapter 13 DNA Q1. Copy the structural formula of deoxyribose sugar. Now indicate where covalent bonds form to link this group to: a a phosphate group b a base group A1. Q2. Give the sequence of bases that will pair

More information

Chapter 11: Molecular Structure of DNA and RNA

Chapter 11: Molecular Structure of DNA and RNA Chapter 11: Molecular Structure of DNA and RNA Student Learning Objectives Upon completion of this chapter you should be able to: 1. Understand the major experiments that led to the discovery of DNA as

More information

The Organic Chemistry of Amino Acids, Peptides, and Proteins

The Organic Chemistry of Amino Acids, Peptides, and Proteins Essential rganic Chemistry Chapter 16 The rganic Chemistry of Amino Acids, Peptides, and Proteins Amino Acids a-amino carboxylic acids. The building blocks from which proteins are made. H 2 N C 2 H Note:

More information

DNA Activity Model. For complete technical support call Objectives: Use models to demonstrate complementary base pairing

DNA Activity Model. For complete technical support call Objectives: Use models to demonstrate complementary base pairing Neo/SCI Teacher s Guide DNA Activity Model Objectives: Use models to demonstrate complementary base pairing Learn the components of nucleotides. Model the double helix structure of DNA #30-1335 For complete

More information

Nucleic Acids and Proteins

Nucleic Acids and Proteins Unit 7, xx,lesson Lesson1 xx Unit Unit xx, Lesson xx 1 ucleic cids and roteins macromolecules proteins D R composed of monomers Essential Questions Keywords What is a monomer, and what relation does it

More information

Amino Acids and Proteins

Amino Acids and Proteins Amino Acids and Proteins Proteins are composed of amino acids. There are 20 amino acids commonly found in proteins. All have: N2 C α R COO Amino acids at neutral p are dipolar ions (zwitterions) because

More information

Chemical Basis of Life Module A Anchor 2

Chemical Basis of Life Module A Anchor 2 Chemical Basis of Life Module A Anchor 2 Key Concepts: - Water is a polar molecule. Therefore, it is able to form multiple hydrogen bonds, which account for many of its special properties. - Water s polarity

More information

DNA (Deoxyribonucleic Acid)

DNA (Deoxyribonucleic Acid) DNA (Deoxyribonucleic Acid) Genetic material of cells GENES units of genetic material that CODES FOR A SPECIFIC TRAIT Called NUCLEIC ACIDS DNA is made up of repeating molecules called NUCLEOTIDES Phosphate

More information

Transcription Activity Guide

Transcription Activity Guide Transcription Activity Guide Teacher Key Ribonucleic Acid (RNA) Introduction Central Dogma: DNA to RNA to Protein Almost all dynamic functions in a living organism depend on proteins. Proteins are molecular

More information

Molecular Biology Basic Concepts

Molecular Biology Basic Concepts Molecular Biology Basic Concepts Prof. Dr. Antônio Augusto Fröhlich Charles Ivan Wust LISHA - UFSC {guto charles}@lisha.ufsc.br http://www.lisha.ufsc.br/~{guto charles} September 2003 September 2003 http://www.lisha.ufsc.br/~guto

More information

Protein Folding. Cell/mol bio lab. Proteins are like a long spaghetti noodle, folded back upon itself over and over

Protein Folding. Cell/mol bio lab. Proteins are like a long spaghetti noodle, folded back upon itself over and over Protein Folding Cell/mol bio lab Proteins are like a long spaghetti noodle, folded back upon itself over and over Why study the 3-D 3 D shape of a protein? (go to Cell Biology web site from my home page)

More information

Guided Reading Activities

Guided Reading Activities Name Period Chapter 3: The Molecules of Cells Guided Reading Activities Big idea: Introduction to organic compounds Answer the following questions as you read modules 3.1 3.3: 1. Is this molecule an organic

More information

DNA Replication & Protein Synthesis. This isn t a baaaaaaaddd chapter!!!

DNA Replication & Protein Synthesis. This isn t a baaaaaaaddd chapter!!! DNA Replication & Protein Synthesis This isn t a baaaaaaaddd chapter!!! The Discovery of DNA s Structure Watson and Crick s discovery of DNA s structure was based on almost fifty years of research by other

More information

Chemistry is the foundation of all living organisms. All basic physiological processes of life take place at the chemical level

Chemistry is the foundation of all living organisms. All basic physiological processes of life take place at the chemical level The Chemical Level of Organization Objectives Describe atomic structure Compare the ways atoms combine to form molecules and compounds Distinguish among the major types of chemical reactions Describe the

More information