31 ST ANNUAL ADVANCES IN HEART DISEASE

Division of Cardiology Department of Medicine School of Medicine University of California 31 ST ANNUAL ADVANCES IN HEART DISEASE JW MARRIOTT SAN FRANCISCO UNION SQUARE SAN FRANCISCO, CA FRIDAY SUNDAY Peter Ganz, MD, FACC Chief, Division of Cardiology ; Maurice Eliaser Distinguished Nora F. Goldschlager, MD, FACC Chief, Clinical Cardiology Director, CCU, ECG Lab and Pacemaker Clinic ; Gabriel Gregoratos, MD, FACC Emeritus Endorsed by American College of Cardiology, California Chapter

31 ST ANNUAL ADVANCES IN HEART DISEASE JW Marriott Union Square, California Our 31st annual course, Advances in Heart Disease, will again strive to present topics that highlight new evidencebased medicine findings reported within the last one to two years that impact upon clinical practice. These will range across a variety of cardiologic subspecialty interests including preventive cardiology, congenital heart disease, interventional cardiology, electrophysiology, cardiac imaging, cardiovascular pharmacotherapy, clinical cardiology, and cardiac surgery. Our faculty will include a distinguished group of visiting academicians from North America together with outstanding teachers and clinicians from the. We plan to offer adequate time after each set of lectures in a given topic area to permit a panel discussion as well as to extend to our attendees the opportunity to comment and/or direct questions to the faculty. TARGET AUDIENCE This course is intended for cardiovascular specialists, practicing cardiologists, internists, family physicians, cardiovascular and critical care nurses and paraphysicians. EDUCATIONAL OBJECTIVES This course is intended to facilitate changes in practice with respect to: Refining management of lipid disorders, stroke, hypertrophic cardiomyopathy, systolic and diastolic heart failure, atrial fibrillation, cardio-metabolic syndrome and the effects of bariatric surgery, STEMI and Non-STEMI, peripheral artery disease, stress cardiomyopathy, and infiltrative heart diseases Refining considerations for heart transplantation and ventricular tachycardia ablation Refining evaluation of cardiovascular risks associated with athletic participation Recognizing and working more effectively with important psychosocial factors in cardiovascular disease ACCREDITATION The University of California, School of Medicine (UCSF) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. UCSF designates this live activity for a maximum of 16.50 AMA PRA Category 1 Credits TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. This CME activity meets the requirements under California Assembly Bill 1195, continuing education and cultural and linguistic competency. Nurses: For the purpose of recertification, the American Nurses Credentialing Center accepts AMA PRA Category 1 Credits TM issued by organizations accredited by the ACCME. Family Physicians: Application for CME credit has been filed with the American Academy of Family Physicians. Determination of credit is pending. Physician Assistants: AAPA accepts category 1 credit from AOACCME, Prescribed credit from AAFP, and AMA PRA Category 1 Credits TM from organizations accredited by the ACCME. Improving anti-platelet therapy for cardiovascular diseases

31ST ANNUAL ADVANCES IN HEART DISEASE FRIDAY, DECEMBER 12, 2014 7:00 am Registration and Continental Breakfast 8:10 Welcome and Symposium Perspective Dr. Peter Ganz TOPICS OF GENERAL INTEREST Presiding: Dr. Melvin Cheitlin 8:15 Hypertrophic Cardiomyopathy: State of the Art Management Dr. Barry Maron 8:50 Congenital Heart Disease: Emergencies in Adult Dr. Vaikom Mahadevan Congenital Heart Disease 9:25 Pre-Participation Screening in Sports Dr. Barry Maron Controversies in Predicting Sudden Death 10:00 Break/Refreshments 10:25 Current Stroke Management Dr. Claude Hemphill 10:55 Panel Discussion of Audience Questions Drs. Maron, Mahadevan, Hemphill ECG WORKSHOP 11:25 Interesting ECG Tracings Audience Participation Dr. Nora Goldschlager 12:00 pm Hosted Luncheon CORONARY AND PERIPHERAL ARTERY DISEASE Presiding: Dr. Peter Ganz 1:20 Anti-platelet Therapy in ACS and After Stenting Dr. Jessica Mega 1:55 Peripheral Artery Disease State of the Art Diagnosis Dr.Yerem Yeghiazarians and Management 2:30 Coronary Intervention An Update Dr. John MacGregor 3:05 Break/Refreshments 3:30 The Impact of Chronic Kidney Disease on Dr. Jessica Mega Cardiovascular Disease 4:05 Psychosocial Factors and the Cardiovascular System Dr. Mary Whooley 4:40 Panel Discussion of Audience Questions Drs. Mega, Yeghiazarians, MacGregor and Whooley 5:10 pm Adjourn SATURDAY, DECEMBER 13, 2014 7:30 am Continental Breakfast PREVENTION OF CARDIOVASCULAR DISEASE Presiding: Dr. Gabriel Gregoratos 8:10 Making Sense of the New Lipid Guidelines One year Later Dr. Binh An Phan 8:45 Evaluation and Management of Cardiac Patients Dr. Gabriel Gregoratos Undergoing Non-Cardiac Surgery: What is New? 9:20 Use of High-Sensitivity Troponin for Risk Stratification Dr. Alan H.B. Wu in Primary Care 9:55 Mechanisms Underlying Improvements of Glucose Dr. Peter Havel and Lipid Metabolism following Bariatric Surgery in Insulin Resistance and Type-2 Diabetes 10:30 Break/Refreshments 10:55 Panel Discussion of Audience Questions Drs. Phan, Gregoratos, Wu, and Havel 11:20 ELLIOT RAPAPORT, MD KEYNOTE LECTURE: Dr. Peter Ganz Biology of Aging 12:00 pm Lunch (on your own) ARRHYTHMIAS Presiding: Dr. Nora Goldschlager 1:15 Atrial Fibrillation Ablation Should it be First Line Therapy? Dr. Gregory Marcus 1:45 Challenging the Fundamental Assumptions of the Dr. Mintu Turakhia Atrial Fibrillation/Stroke Relationship

JW Marriott Union Square, California SATURDAY, DECEMBER 13, 2014 (CONT D) ARRHYTHMIAS (CONT D) 2:15 Indications for and Outcomes of Ventricular Dr. Ed Gerstenfeld Tachycardia Ablation 2:45 Recent Advances in Pacemaker and ICD Technologies Dr. Mintu Turakhia 3:15 Panel Discussion of Audience Questions Drs. Marcus, Turakhia, and Gerstenfeld 3:40 Break/Refreshments TOPICS OF GENERAL INTEREST Presiding: Dr. Nora Goldschlager 4:00 Management Issues in Stress Cardiomyopathy Dr. Robert J. Lundstrom 4:30 Infiltrative Heart Diseases Dr. Mary Gray 5:00 Panel Discussion of Audience Questions Drs. Lundstrom and Gray 5:20 pm Adjourn SUNDAY, DECEMBER 14, 2014 7:30 am Continental Breakfast HEART FAILURE Presiding: Dr. Peter Ganz 8:15 Heart Failure with Preserved Ejection Fraction (HFpEF): Dr. Ramin Farzaneh-Far Final Frontier or Fool s Errand? 8:50 Cardiorenal Syndrome: What is it and How to Treat It Dr. Liviu Klein 9:25 Advanced Therapies for Heart Failure Dr. Arthur Hill 10:00 Cardiac Transplantation: An Update Dr. Teresa DeMarco 10:35 Panel Discussion of Audience Questions Drs. Farazaneh-Far, Klein, Hill and DeMarco 11:05 am Adjourn Dr. Peter Ganz GENERAL INFORMATION Pre-registration is preferred to ensure that registrants receive a syllabus at the course. HOW TO ENROLL Tuition: $600 Physicians ($650 after November 28, 2014) $415 Allied Health Professionals/ Residents/Fellows ($465 after November 28, 2014) Payment may be made by Visa, MasterCard, AmEx or check. REGISTER VIA: Online: www.cme.ucsf.edu Mail: Complete course registration form and send with payment to: UCSF Office of CME P.O. Box 45368, CA 94145-0368 Fax: Fax completed registration form to: (415) 502-1795 (be sure to include your credit card number) Phone: To register by phone or to inquire about registration status, please call (415) 476-5808. On-Site Registration: Generally we are able to accommodate on-site registration at our courses. Please check our website for up-to-date information on the course: www.cme.ucsf.edu REFUND POLICY Cancellations received in writing before the first day of the course will be refunded, less a $75 administrative fee. No refunds will be made on cancellations received after that date. CONFERENCE LOCATION The JW Marriott is a luxury hotel near Union Square, ideally located near Market Street, Moscone Convention Center, Chinatown and the Financial District. A block of guestrooms has been reserved at the special UCSF discounted conference rate of $209. To make hotel reservations on-line, please visit www.cme.ucsf.edu information is located under Travel & Lodging. If you prefer to telephone in your reservation, call (800) 468-3571 and please identify yourself as a member of this UCSF conference to receive the special rate. The contracted cut off date is November 20, 2014, or until the group room block is filled, whichever comes first. By staying at the host hotel, you help UCSF meet its contractual obligations and keep registration fees reasonable. Please take this into consideration when making your accommodation decisions. For air transportation and rental car discount information, please visit our website at www.cme.ucsf.edu.

0569 Office of Continuing Medical Education UCSF Box 0742, CA 94143-0742 E Printed on Recycled Paper For more information or to register online visit our website at www.cme.ucsf.edu. You may also reach us by calling the Office of CME at (415) 476-4251 or email info@ocme.ucsf.edu. Upcoming CME Courses 31st Annual Symposium Cardiology for the Practitioner October 20-22, 2014 Yosemite Lodge at the Falls, Yosemite, CA UCSF Vascular Symposium 2015 April 16-18, 2015 Hotel Nikko,, CA COURSE DIRECTOR Peter Ganz, MD, FACC Chief, Division of Cardiology ; Maurice Eliaser Distinguished CO-DIRECTORS Nora F. Goldschlager, MD, FACC Director, CCU, ECG Lab and Pacemaker Clinic ; Gabriel Gregoratos, MD, FACC Emeritus VISITING COURSE FACULTY Peter J. Havel, DVM, PhD Professor, Department of Molecular Biosciences & Nutrition, Davis, CA Robert J. Lundstrom, MD Interventional Cardiologist Program Director, Cardiology Fellowship; Kaiser Permanente, CA Barry J. Maron, MD, FACC Director, Hypertrophic Cardiomyopathy Center at Minneapolis Heart Institute Foundation Minneapolis, MN VISITING COURSE FACULTY (CONT D) Jessica L. Mega, MD Associate Brigham and Women Hospital Harvard Medical School Boston, MA Minang (Mintu) Turakhia, MD, MAS Assistant Professor of Cardiovascular Medicine; Director of Cardiac Electrophysiology, Health Research and Policy, Palo Alto Veterans Affairs Health Care System Stanford University, Palo Alto, CA COURSE FACULTY ( ) Melvin Cheitlin, MD, FACC Emeritus Cardiology Staff, Teresa De Marco, MD, FACC Co-Director, Advanced Heart Failure Ramin Farzaneh-Far, MD Assistant Edward P. Gerstenfeld, MS, MD Chief of Electrophysiology Mary Gray, MD Director, Cardiology Clinics J. Claude Hemphill, III, MD, MAS, FNCS Professor of Neurology and Neurological Surgery Chief, Neurology Service COURSE FACULTY (CONT D) Arthur Hill, MD Professor of Surgery Chief, Thoracic Surgery Liviu Klein, MD, MS Assistant Division of Cardiology Director, Mechanical Circulatory Support & Heart Failure Device Programs John S. MacGregor, MD, PhD, FACC Director, Cardiac Catheterization Laboratory and Interventional Cardiology Vaikom S. Mahadevan, MD Associate Gregory Marcus, MD, MAS Associate Division of Cardiology Director of Clinical Research Binh An Phan, MD Associate Mary A. Whooley, MD, FACP, FAHA, FACC, Epidemiology & Biostatistics Director of Cardiac Rehabilitation, VA Medical Center Alan H.B. Wu, PhD Professor of Laboratory Medicine Chief, Clinical Chemistry & Toxicology Laboratory Yerem Yeghiazarians, MD, FACC Associate Co-Director of the UCSF Adult Cardiac Catheterization Laboratory; Director of Peripheral Interventional Cardiology Program Director of Translational Cardiac Stem Cell Program

Course Registration Form www.cme.ucsf.edu E R. NE TION R 101 nto St Laguna St Bay St Laguna St Buchanan St Buchanan St Octavia St 31 ST ANNUAL ADVANCES IN HEART DISEASE JW Marriott Union Square, California æ Dr. æ Ms. æ Mr. æ Mrs. Last Name First M.I. Degree Specialty Address City State Zip Daytime Phone Fax Email Address Label Code Letter (see address label: example, A, B, C, D, etc.) Would you like to be on our priority email list? Yes No Date of birth to be used as OCME registrant number: / / X X Month Day SAN Please indicate if you have any special needs: FRANCISCO BAY Registration Fees (Receipt/Confirmation will be mailed within two to four weeks): $600 Physicians ($650 after November 28, 2014) 39 $415 Nurses/Pharmacist/Allied Health Professionals/Residents/Fellows ($465 after November 28, 2014) THE Make checks PARK MARITIME payable to UC Regents CANNERY Please CENTER charge GHIRARDELLI my credit card: Visa MasterCard AmEx for $ Polk St / SF ART Card # INSTITUTE Expiration date STS PETER AND PAUL COIT NORTH BEACH TOWER PLAYGROUND Name on Card (Please Print) Authorized SignatureLEVI'S PLAYGROUND WASHINGTON Refund Policy: Cancellations Neighborhoods received in writing before SQUARE the first day of the course will be refunded, NORTH Points less a $75 administrative fee. RUSSIAN of Interest No refunds will be made BEACH on cancellations received after that BROADWAY date. Please check our website for Cable up Car to Lines date information on the course: www.cme.ucsf.edu Octavia St Gough St Gough St Franklin St AQUATIC Franklin St Van Ness Av 101 Cable Car Line Jefferson St Beach St North Point St Bay St Francisco St Francisco St Chestnut St Chestnut St Lombard St Greenwich St Polk St Larkin St Filbert St Hyde St Kearny St Kearny St Kearny St Grant Av Grant Av Grant Av Stockton St Stockton St Powell St Powell St Mason St Mason St Mason St Taylor St Taylor St Taylor St Jones St Jones St Lombard St Greenwich St Filbert St Union St Union St Leavenworth St Green St Green St Larkin St Hyde St Leavenworth St Jones St Vallejo St Broadway Post St ejo St Washington St Broadway Pacific St Vallejo St Jackson St Pacific St Clay St Jackson St Washington St Sacramento St California St Clay St n St Sacramento St Pine St California St Bush St Pine St ia St Bush St st St Ellis St t Sutter St Geary St St Post St ter St Geary St O Farrell St O Farrell St eary Expwy Ellis St Eddy St PACIFIC HEIGHTS FORT MASON CENTER COW HOLLOW JAPAN TOWN JAPANESE CULTURAL & TRADE CENTER Mail to : YOUTH HOSTEL FT. MASON VISITOR OCTAGON HOUSE ST. MARY'S CATHEDRAL UCSF Office of CME P.O. Box 45368, CA 94145-0368 Fax: (415) 502-1795 MUSEUM Peter Yorke wy Starr King Wy SQUARE Pol CROOKED STREET JW Marriott LAFAYETTE Union Square PARK 515 Mason Street, CA 94102 (800) 468-3571 http://www.marriott.com Landmarks MICHELANGELO HILL Parks Larkin Hyde St NOB HILL Leavenworth St FISHERMAN'S WHARF GRACE CATHEDRAL SAN FRANCISCO Powell St MASONIC AUDITORIUM PIER Columbus Av Cyril Magnin St UNDERWATER WORLD AQUARIUM CHINATOWN Financial District Online registration: www.cme.ucsf.edu Registration Information: (415) 476-5808 Course Information: (415) 476-4251 Stockton St Market St Montgomery St PORTSMOUTH SQUARE UNION SQUARE SF SHOPPING The Embarcadero Sansome St TELEGRAPH HILL BANK OF AMERICA BLDG. POWELL ST. STATION Montgomery St Montgomery St Battery St TRANSAMERICA PYRAMID BLDG. FINANCIAL DISTRICT CROCKER GALLERIA PLAZA Sansome St New Montgomery St CENTER FOR THE ARTS AT YERBA BUENA GARDENS Front St Battery St 2nd St Davis St WALTON PARK MOSCONE CONVENTION MDM15A02 1st St Drumm St EMBARCADERO SHOPPING CENTER GOLDEN GATE UNIV. MONTGOMERY ST. STATION JW Marriott SF MUSEUM OF MODERN ART TRANSBAY TERMINAL PIER (Pedestrian) Market St Fremont St JUSTIN HERMAN PLAZA EMBARCADERO STATION Mission St Beale St RINCON CENTER Main St WORLD TRADE CTR. The Embarcadero Spear St Howard St FERRY BUILDING Steuart St Folsom St Harrison St Van Ness Av Va