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Meeting programm 22-23 April 2013 Information and registration: www.medical-cluster.ch/events Congress Centre Kursaal Interlaken The conference The 2013 [MEET THE EXPERT] Implants is dedicated to experts and persons interested in the field of active and passive implants. The program includes expert talks as well as short presentations. Discussions and networking will additionally take place at the tabletop exhibition and poster presentation area. The aim of the event is to present new developments, promote the exchange of know-how, and trigger collaborations between implant producers, subcontractors and end users. Conference languages are English and German with translation from English to German and vice-versa. Tabletop exhibition The tabletop exhibition will take place during the conference (exhibitor fee CHF 1 500.00, excl. VAT). Exhibitors have the opportunity to give a one minute talk during the plenary session. Registration for the tabletop exhibition can be found at: www.medical-cluster.ch/mte_participant Organization Peter Biedermann, Medical Cluster peter.biedermann@medical-cluster.ch Lukas Eschbach, RMS Foundation lukas.eschbach@rms-foundation.ch Ralf Schindel, inspire, irpd schindel@inspire.ethz.ch Secretariat Medical Cluster Wankdorffeldstrasse 102 Postfach 261 CH-3000 Bern 22 Tel. +41 31 335 62 38 michelle.meyer@medical-cluster.ch www.medical-cluster.ch Industry partner 1/5

Meeting Program Monday, 22nd April 2013 From 09:30 Registration 10:00-10:15 Welcome Session 1 Chair: Dr. Lukas Eschbach 10:15-11:00 Straumann s view of the dental market (industry partner) and the importance of Time to Market in a fast changing Industry (EN); Dr. Sandro Matter, Institut Straumann AG 11:00-11:30 Keynote 1: Considerations on Patient Specific Implants (DE); Dr.-Ing. Jörn Seebeck, Zimmer GmbH 11:30-12:00 Flash presentations exhibitors 12:00-13:15 Lunch Session 2 Chair: PD Dr. Christiane Jung 13:15-13:45 Keynote 2: Biocompatible elastomers for 3D biomaterials by additive manufacturing (DE); Dr. Kirsten Borchers, Fraunhofer-Institute for Interfacial Engineering and Biotechnology IGB 13:45-14:15 Keynote 3: Laser for the medical device industry challenges in manufacturing and marking of medical implants (DE); Dr. Alexander Knitsch, TRUMPF Laser- und Systemtechnik GmbH 14:15-14:45 Keynote 4: Electro-activation of passive implants propositions from a technology perspective (DE); Dr. Urban Schnell, Helbling Technik Bern AG 14:45-15:05 Flash presentations posters 15:05-15:30 Break (Exhibition and Poster) Session 3a: Passive implants Chair: Prof. Dr. Michael de Wild 15:30-15:50 Development of a atrial septal occluder using an biodegradable framework (DE); Andreas Weishaupt, Carag AG 15:50-16:10 Is the occurrence of periimplant osteosarcomas related to the use of cast stainless steel plates? (DE); Christoph Sprecher, AO Research Institute 16:10-16:30 Development of a new glenoid implant (DE); Samuel Schenk, Mathys Ltd Bettlach 16:30-16:50 Antibiotic loaded plaster of Paris: Wear of artificial hip joints in the presence of gypsum particles (DE); Dr. sc. Roman Heuberger, RMS Foundation 16:50-17:10 Employing biological and mechanical cues for bone regeneration (DE); Univ.-Prof. Dr.-Ing. Georg N. Duda, Charité - Universitätsmedizin Berlin 17:10-18:30 Exhibition / Poster / Aperitif From 19.00 Dinner at Hotel Metropole Session 3b: Electro-active implants Chair: Dr. Urban Schnell Implantable ceramic MEMS electrodes for cardiac pace makers (EN); Dr. Gurdial Blugan, Empa Product engineering of active implants (DE); Daniel Thommen, Microdul AG Glass encapsulation in intelligent embedded systems (EN); Frédéric Mauron, VALTRONIC PEEK casing for an active implant (EN); Dr. Thomas Degen, Sequana Medical AG Evaluation of process capability of implant manufacturing (DE); Adrian Gammeter, Integrated Scientific Services, ISS AG Key: EN = Lecture in English DE = Lecture in German 2/5

Meeting Program Tuesday, 23rd April 2013 Session 4 Chair: Prof. Dr. Michael de Wild 08:30-09:00 Keynote 5: Application of rapid prototyping in complex osteotomies of malunited bones (EN); Matthias Graf, Uniklinik Balgrist 09:00-09:30 Keynote 6: Trends and developments of high-performance ceramics for implants (DE); Dr. Martin Zimmermann, Metoxit AG 09:30-10:00 Keynote 7: Phase contrast and X-ray dark field imaging: New possibilities for non-destructive testing of materials and components (DE); Dr. Christian Kottler, CSEM 10:00-10:30 Break (Exhibition and Poster) Session 5a: Passive implants Chair: PD Dr. Christiane Jung 10:30-10:50 Latest results in the development of a miniaturized hand held navigation system (DE); Dr. Bruno Knobel, Naviswiss AG 10:50-11:10 Colorimetry on implant surfaces for esthetically demanding applications (DE); Dr. Hans Schmotzer, SigmaRC GmbH 11:10-11:30 CVD coating technology: a high temperature coating alternative for CoCr alloys (EN); Dr. Antonio Santana, IHI Ionbond AG 11:30-11:50 Silver as a lubricant additive in the implant manufacturing (DE); Dr. Bernhard Keller, MOTOREX AG 11:50-12:10 New opportunities for using tantalum for implants with Additive Manufacturing (EN); Ruben Wauthle, LayerWise NV Session 5b: Design, Quality, and RA Chair: Ralf Schindel Breakthroughs in Patient matched medicine through advancements in 3d image analysis (EN); Sebastian De Boodt, Materialise Patient specific implants for orthopedics streamlining through smart software (DE); Jan Stifter, Medivation AG Application of computer tomography in industrial 3d measurements Methods, application, precision (DE); Andreas Flechtmann, Werth Messtechnik GmbH Approval of implants produced with Additive Manufacturing (EN); Oscar Hedin, Arcam AB Regulatory Road for Combination Products (EN); PD Dr. Pierre Mainil-Varlet, Aginko 12:10-13:30 Lunch Session 6 Chair: Lukas Märklin 13:30-13:50 Fixation concept for a ceramic-metal back composite (DE); Dr. Martin Schmidt, Jossi Orthopedics AG 13:50-14:10 Surface property modulation in high-precision cutting of materials for medical applications (EN); Armando Pereira, Agie Charmilles 14:10-14:30 Dental ceramics: past, present, and future (EN); Dr. Simon Jegou, Nobel Biocare Services AG 14:30-14:50 Contemporary dental implant systems: Clinical, biological and mechanical aspects (DE); Dr. med. dent. Urs Brodbeck, Zahnmedizin Zürich-Nord 14:50-15:20 Keynote 8: Specificities of implant-associated infections (DE); Dr. Peter Wahl, Hôpital Cantonal Fribourg 15:20 Conference end 3/5

Poster Session 1 101 million cycle simulator wear characterization of diamond like carbon coated CoCrMo articulating implants Dr. Dominik Jaeger, Empa, Laboratory for Nanoscale Materials Science 2 Smart NiTi constructs for 3D cell culture applications Waldemar Hoffmann, Fachhochschule Nordwestschweiz 3 Effect of ultrasound on the electrochemical deposition of antibacterial copper particles at anodized titanium discs as model for titanium implants PD Dr. Christiane Jung, KKS Ultraschall AG 4 Additive manufactured ceramic/ polymer scaffolds Sabrina Stevanovic, School of Life Sciences FHNW 5 Macroporous titanium coatings for challenging substrates Pierfrancesco Robotti, EUROCOATING 6 Qualitätsdenken - der zukünftige Erfolgsfaktor in der Medizintechnik? Dr. Margit Widmann, SQMT 7 Simulierte Muskel- und Gelenkreaktionskräfte als Randbedingung für belastungsgerechtes Implantatdesign Alexander Nolte, CADFEM GmbH 8 Hemi-Resurfacing Schulterprothesen: Analyse des knöchernen An- und Umbaus Christoph Sprecher, AO Research Institute 9 Biological safety testing on implant devices Carolin Schmied, BSL BIOSERVICE Scientific Laboratories GmbH 10 Erfolgreiche Osseointegration von Titan-Implantaten: neueste Erkenntnisse über Biologische und biomechanische Voraussetzungen Miroslaw Pienkowski, Trinon Titanium GmbH 11 Bestimmung der technischen Sauberkeit von chirurgischen Implantaten und Instrumenten im Rasterelektronenmikroskop Dr. Michael Hiltl, Carl Zeiss Microscopy GmbH 12 Data Analytics: progress without experimental design Dr. Rodolphe Dewarrat, IMSD Sàrl 13 Advanced laser ablation for the surface microstructuring of cardiovascular implants Dr. Jörn Lungershausen, University of Applied Sciences and Arts Northwestern Switzerland 4/5

Registration fee Members of the Medical Cluster, CHF 550.-* Non-members, CHF 650.- * Students (full time, unemployed), CHF 300.-* Single day visit on either Monday or Tuesday, CHF 370.- Dinner on Monday, incl. drinks, CHF 85.- Tabletop exhibition incl. 1 entry, CHF 1 500.- All prices excl. 8% VAT. The prices above include conference entry, materials and documentation and all meals during the meeting. Accommodation and dinner on Monday are not included in the prices. *A discount of CHF 50.- will be applied to participants who register before 26th March 2013. Registration Please register until 17th April 2013 at: www.medical-cluster.ch/mte_participant Registrations are accepted in the order in which they are received and will be confirmed immediately. The fee for registration cancelation up to 7 days before the event is CHF 50.- No refund will be given for cancellations made less than 7 days before the event, though the registrant may transfer the ticket to another person to attend as a replacement. Program committee Dr. Lukas Eschbach, Head of Materials Group RMS Foundation, Bettlach PD Dr. habil. Christiane Jung, Head of R&D KKS Ultraschall AG, Steinen Lukas Märklin, Head of Corp. Manufacturing Technology Center, Institut Straumann AG, Basel Ralf Schindel, Head of Medical Manufacturing inspire, irpd, St. Gallen Dr. Urban Schnell, Vizepräsident und Head of Optics & Sensors, Helbling Technik Bern AG, Liebefeld Prof. Dr. Michael de Wild, Fachhochschule Nordwestschweiz, Muttenz Venue / Travel Congress Centre Kursaal Interlaken Strandbadstrasse 44 How to get there: www.congress-interlaken.ch Hotel For information contact: Interlaken Tourismus Höheweg 37 Phone for information +41 (0)33 826 53 00 Phone for reservation +41 (0)33 826 53 01 Fax +41 (0)33 826 53 75 mail@interlakentourism.ch www.interlaken.ch Sponsors This event is supported by PRODUCTS 5/5