FRIDAY MAY 9, 2014. Seattle, WA

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FRIDAY MAY 9, 2014 ORIN SMITH AUDITORIUM UW Medicine south lake union campus Seattle, WA

Course Description This symposium is designed to bring state of the art information on current research and clinical management in the field of gastrointestinal cancers. A distinguished and internationally renowned faculty panel will share their expertise and foster discussion of the most recent breakthroughs and relevant research findings in GI cancers. The goal of the course is to provide information on clinical innovations and novel therapies to clinicians involved in the care of patients with GI cancers. Attendees will be exposed to new concepts, develop a broad understanding in management protocols, and receive updates on recent advances in therapy. Course Objectives Discuss updates on cutting-edge scientific research, state-of-the art treatment, and challenges in the treatment of gastrointestinal cancers Illustrate evidence-based research that affects the practice of clinical gastrointestinal oncology Describe current surgical, medical, and radiation oncology techniques in both early stage and advanced disease/cancers Intended Audience This conference is designed for physicians and allied health professionals who manage patients with GI cancers. Accreditation The is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The designates this live activity for a maximum of 7.25 AMA PRA Category I Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Fees & Registration Information Advanced Registration After April 11, 2014 Physicians $150 $195 SCCA Network Members $100 $150 Allied Health/Fellows $100 $150 UW Residents & Fellows $75 $150 The fee for this course includes catering, all instruction materials, and transcript of AMA PRA Category 1 Credits. To ensure enrollment, please complete the enclosed registration form and mail/fax it with the appropriate tuition. Allow up to 10 working days to receive your written confirmation of enrollment via email. Driving and parking instructions will be included with registration confirmation. If you have not received written confirmation prior to your departure for the course, contact the SCCA Network Physician Education Office (PEO) at: (206) 288-1066. The SCCA Network PEO will not be responsible for expenses incurred by an individual who is not confirmed and for whom space is not available at the course. If you have any additional questions, please contact the SCCA Network PEO at sccanet@seattlecca.org or (206) 288-1066. Registration Options 1. Online at www.seattlecca.org/cme 2. Fax registration form to (206) 288-1310 Cancellation policy 3. Mail registration form to: SCCA Network PEO 825 Eastlake Ave. E, LG-200 Seattle, WA 98109-1023 The SCCA Network PEO must receive written notification of cancellation and refund requests no later than May 1, 2014. A $40 processing fee will be deducted from the refunded amount. No refunds will be issued for cancellations received after May 1, 2014. SCCA is not responsible for any other costs incurred such as non-refundable airline tickets or hotel penalties. Conference Location & Parking UW Medicine, South Lake Union Campus, Orin Smith Auditorium, 850 Republican St., Seattle, WA, 98109 Paid parking available in the garage as well as metered-street parking.

Co-Chairs Elena Gabriela Chiorean, MD Associate Professor, Division of Medical Oncology Director of Clinical Research, GI Oncology Program Seattle Cancer Care Alliance Alessandro Fichera, MD Professor, Division of General Surgery Director, Colorectal Surgical Oncology Program Seattle Cancer Care Alliance William Grady, MD Professor, Division of Gastroenterology Member, Clinical Research Division Fred Hutchinson Cancer Research Center Medical Director, GI Cancer Prevention Program Seattle Cancer Care Alliance Edward Kim, MD Assistant Professor, Department of Radiation Oncology GI Oncology 2014: REsearch to Practice

Guest Faculty Christopher Crane, MD Professor, Department of Radiation Oncology Program Director and Section Chief, Gastrointestinal Section Director, Residency Program Associate Medical Director, Gastrointestinal Center The University of Texas MD Anderson Cancer Center Lee Ellis, MD Professor, Division of Surgery Professor, Department of Molecular and Cellular Oncology The University of Texas MD Anderson Cancer Center Faculty Smith Apisarnthanarax, MD Associate Professor, Department of Radiation Oncology K. Scott Baker, MD, MS Professor, Division of Medical Oncology Director, Pediatric Blood & Marrow Transplantation and Survivorship Fred Hutchinson Cancer Research Center Teresa Brentnall, MD Professor, Division of Gastroenterology Krishnavel Chathadi, MD Associate Professor, Department of Medicine Mac Cheever, MD Director, Cancer Immunotherapy Trials Network Member, Clinical Research Division Fred Hutchinson Cancer Research Center Professor, Division of Medical Oncology GI Oncology 2014: REsearch to Practice

Faculty Andrew Coveler, MD Assistant Professor, Division of Medical Oncology Assistant Member, Clinical Research Division Fred Hutchinson Cancer Research Center William Harris, MD Assistant Professor, Division of Medical Oncology Assistant Member, Clinical Research Division Fred Hutchinson Cancer Research Center Sunil Hingorani, MD, PhD Associate Member, Clinical Research Division and Public Health Sciences Division, Fred Hutchinson Cancer Research Center Associate Professor, Division of Medical Oncology Wui-Jin Koh, MD Professor, Department of Radiation Oncology Affiliate Member, Clinical Research Division Fred Hutchinson Cancer Research Center Medical Director, Radiation Oncology Seattle Cancer Care Alliance Neeraj Lalwani, MD Assistant Professor, Division of Body Imaging Gary Mann, MD, BCh Associate Professor, Division of General Surgery Brant Oelschlager, MD Professor, Division of General Surgery Director, Gastrointestinal Surgery Section and Center for Videoendoscopic Surgery GI Oncology 2014: REsearch to Practice

Siddharth Padia, MD Assistant Professor, Division of Interventional Radiology Shilpen Patel, MD Associate Professor, Department of Radiation Oncology James Park, MD Associate Professor, Hepatobiliary and Pancreatic Surgical Oncology Venu Pillarisetty, MD Assistant Professor, Division of General Surgery Veena Shankaran, MD Associate Professor, Division of Medical Oncology Karen Syrjala, PhD Professor, Department of Psychiatry and Behavioral Sciences Co-Director, Survivorship Fed Hutchinson Cancer Research Center Thomas Varghese, MD, MS Associate Professor, Division of Cardiothoracic Surgery Raymond Yeung, MD Professor, Division of Surgical Oncology Director, Liver Tumor Clinic GI Oncology 2014: REsearch to Practice

Program 7:15 a.m. Registration and Continental Breakfast 8:00 a.m. Welcome and Introduction Upper GI Session Moderator Veena Shankaran, MD 8:10 a.m. Updates in Systemic Therapy for Gastroesophageal Cancers Veena Shankaran, MD 8:30 a.m. Minimally Invasive Surgery for Esophageal Cancer Brant Oelschlager, MD 8:50 a.m. Endoscopic Treatment of Early Esophageal Cancer Krishnavel Chathadi, MD 9:10 a.m. Case Presentation and Panel Discussion Brant Oelschlager, MD; Shilpen Patel, MD; Veena Shankaran, MD; Thomas Varghese, MD Pathways and Targets in Gastrointestinal Cancers 9:30 a.m. Pathways, Targets and Pipeline Drugs for GI Cancers Elena Gabriela Chiorean, MD 9:50 a.m. Break Pancreas Session Moderator Sunil Hingorani, MD, PhD 10:05 a.m. Enzymatic Targeting Sunil Hingorani, MD, PhD 10:25 a.m. Role of Radiotherapy in Management of Pancreatic Cancer Wui-Jin Koh, MD 10:45 a.m. Earlier Detection of Pancreatic Cancer Teresa Brentnall, MD 11:05 a.m. Case Presentation and Panel Discussion Andrew Coveler, MD; Sunil Hingorani, MD, PhD; Wui-Jin-Koh, MD; Venu Pillarisetty, MD Keynote 11:25 a.m. Keynote Speaker: Stereotactic Ablative Radiation Therapy (SBRT) for Primary and Metastatic Liver Tumors Chris Crane, MD 11:55 a.m. Lunch Cancer Survivorship: Enhancing Care and Quality of Life for Survivors K. Scott Baker, MD, MS & Karen Syrjala, PhD GI Oncology 2014: REsearch to Practice

Hepatobiliary Session Moderator: Raymond Yeung, MD 12:55 p.m. Surgical Management of HCC Raymond Yeung, MD 1:15 p.m. Emerging Therapies for Liver Cancer Siddharth Padia, MD 1:35 p.m. Medical Therapies for Liver Cancer William Harris, MD 1:55 p.m. Case Presentation and Panel Discussion Smith Apisarnthanarax, MD; William Harris, MD; Sid Padia, MD; Ray Yeung, MD Keynote 2:15 p.m. Keynote Speaker: Challenging Classic Views of The Role of the Vasculature in Human Colon Cancer Lee Ellis, MD 2:45 p.m. Break Immunotherapy 3:00 p.m. Immunotherapy & GI Cancer Mac Cheever, MD Lower GI Session Moderator Alessandro Fichera, MD 3:20 p.m. Multidisciplinary Evaluation of Colorectal Cancer Alessandro Fichera, MD; William Grady, MD; Neeraj Lalwani, MD 4:00 p.m. Updates in Radiotherapy for Rectal Cancer Edward Kim, MD 4:20 p.m. Cytoreductive Surgery (CRS) and Heated Intraperitoneal Chemotherapy (HIPEC) for Gastrointestinal Carcinomatosis: Helpful or Harmful? Gary Mann, MD, BCh 4:40 p.m. Case Presentation and Panel Discussion Elena Gabriela Chiorean, MD; Alessandro Fichera, MD; Edward Kim, MD; Gary Mann, MD, BCh; James Park, MD 5:00 p.m. Adjourn GI Oncology 2014: REsearch to Practice

Registration Form GI Oncology 2014: Research to practice May 9, 2014 Registration Fee Advanced Registration After April 11, 2014 Physicians $150 $195 SCCA Network Members $100 $150 Allied Health/Fellows $100 $150 UW Residents & Fellows $75 $150 Send completed registration form and payment to: SCCA Network Physician Education Office 825 Eastlake Ave. E., LG-200 Seattle, WA 98109-1023 Credit card registrations may be faxed to: (206) 288-1310. First Name Middle Initial Last Name Title MD DO PhD RN ARNP PA Other: SCCA Network Member Address City State Zip Code Phone ( ) - Fax ( ) - E-mail Check Enclosed for $ (U.S. funds make payable to Seattle Cancer Care Alliance) Charge (check one) Visa Mastercard $ Print name on the card as it appears Card number Exp Date / Signature

SCCA Network Physician Education Office 825 Eastlake Avenue East, LG-200 Seattle, Washington 98109-1023