Resolution Scanning Probe Stereoscopic Tunneling Current Wavelength FIGURE 5 LIGHT WAVE FIGURE 6 WAVELENGTHS USED

Transcription

1 CHAPTER ONE: INTRODUCTION... 1 STUDY BACKGROUND... 1 STUDY GOALS AND OBJECTIVES... 1 INTENDED AUDIENCE... 1 SCOPE AND FORMAT OF REPORT... 2 METHODOLOGY AND INFORMATION SOURCES... 2 ANALYST CREDENTIALS... 3 RELATED BCC REPORTS... 3 BCC ONLINE SERVICES... 4 DISCLAIMER... 4 CHAPTER TWO: SUMMARY... 5 SUMMARY TABLE MARKET FOR MICROSCOPES, ACCESSORIES, AND SUPPLIES, THROUGH 2016 ($ MILLIONS)... 5 SUMMARY FIGURE MARKET FOR MICROSCOPES, ACCESSORIES, AND SUPPLIES, ($ MILLIONS)... 5 SUMMARY (CONTINUED)... 6 CHAPTER THREE: MICROSCOPY OVERVIEW... 7 GENERAL DESCRIPTION... 7 DEFINITIONS... 7 Charged Particle... 7 Compound Microscope... 7 Confocal Microscope... 7 Depth of Field... 7 Dispersion... 8 Eyepiece... 8 Inverted Microscope... 8 Immersion Media... 8 Lens... 8 FIGURE 1 MAGNIFYING LENS PRINCIPLES... 9 Magnification... 9 Nanoscale... 9 Near Field Numerical Aperture Objective Phase Shift FIGURE 2 LIGHT WAVE PHASES Polarization FIGURE 3 POLARIZATION Reflected Light Microscopes Reflecting Microscope Refraction FIGURE 4 REFRACTION... 13

2 Resolution Scanning Probe Stereoscopic Tunneling Current Wavelength FIGURE 5 LIGHT WAVE FIGURE 6 WAVELENGTHS USED IN OPTICAL MICOSOCOPY (NM) BRIEF HISTORY OF MICROSCOPY Brief History of Microscopy (Continued) TYPES OF MICROSCOPES OPTICAL MICROSCOPES Description and Applications TABLE 1 TYPES AND MAIN APPLICATIONS OF OPTICAL MICROSCOPES Upright (Compound) Microscopes Binocular Stereomicroscopes Polarizing Microscopes Metallographic Microscopes Reflecting Microscopes FIGURE 7 REFLECTING MICROSCOPE Phase Contrast Microscopes FIGURE 8 BASIC PRINCIPLE OF A PHASE CONTRAST MICROSCOPE Fluorescence Microscope FIGURE 9 FLUORESCENCE MICROSCOPY PRINCIPLES FIGURE 10 FLUORESCENCE MICROSCOPE LAYOUT Confocal Microscopes Confocal Microscopes (Continued) FIGURE 11 PRINCIPLES OF CONFOCAL MICROSCOPY Confocal Microscopes (Continued) Near-Field Scanning Optical Microscopes FIGURE 12 SCANNING NEAR FIELD OPTICAL MICROSCOPE PRINCIPLES Inverted Microscopes Other Types of Optical Microscope Advanced Confocal Microscopy Phase-Sensitive Scatter-Field Optical Imaging Stochastic Optical Reconstruction Microscopy Stimulated Emission Depletion Microscopy Structured Illumination Microscopy Second Harmonic Generation Microscopy Super Resolution Fluorescence Microscopy Coherent Anti-Stokes Raman Scattering (CARS) Microscopy... 35

3 Simultaneous Light Scattering Microscopy Pi Microscopy Patent Analysis Technologies TABLE 2 U.S. OPTICAL MICROSCOPY PATENTS AS OF JUNE 15, 2011 (NUMBER OF PATENTS BY TYPE OF TECHNOLOGY) FIGURE 13 OPTICAL MICROSCOPY PATENTS, BY TYPE OF TECHNOLOGY, AS OF JUNE 15, 2011 (PERCENT OF TOTAL PATENTS) Trends Over Time TABLE 3 OPTICAL MICROSOCOPY PATENTS ISSUED ANNUALLY, BY TYPE OF TECHNOLOGY, (NUMBER OF PATENTS) FIGURE 14 OPTICAL MICROSOCOPY PATENTS ISSUED ANNUALLY, BY TYPE OF TECHNOLOGY, (NUMBER OF PATENTS) Patent Holders TABLE 4 MAJOR OPTICAL MICROSCOPY PATENT HOLDERS (NUMBER/%) FIGURE 15 MAJOR OPTICAL MICROSCOPY PATENT HOLDERS (%) TABLE 5 OPTICAL MICROSCOPY PATENT HOLDERS, BY TECHNOLOGY TYPE (NUMBER OF PATENTS) FIGURE 16 MAJOR OPTICAL MICROSCOPY PATENT HOLDERS BY TECHNOLOGY TYPE (PERCENTAGES OF TOTAL PATENTS) Manufacturers TABLE 6 OPTICAL MICROSCOPE MANUFACTURERS CHARGED PARTICLE MICROSCOPES Description and Applications TABLE 7 TYPES AND PRIMARY APPLICATIONS OF CHARGED PARTICLE MICROSCOPES Transmission Electron Microscopes Transmission (Continued) FIGURE 17 TRANSMISSION ELECTRON MICROSCOPE Scanning Electron Microscopes FIGURE 18 SCANNING ELECTRON MICROSCOPE FIGURE 19 SCANNING ELECTRON MICROSCOPE SAMPLE INTERACTION Environmental Scanning Electron Microscope Field Emission Scanning Electron Microscopes Field Ion Microscopes Electron Probe Microanalyzer Scanning Transmission Electron Microscopes High Voltage Electron Microscopes Focused Ion Beam Microscopes... 53

4 Reflection Electron Microscope Low Energy Electron Microscopy Photoelectron Emission Microscope Patent Analysis Technologies FIGURE 20 U.S. CHARGED PARTICLE MICROSCOPY PATENTS BY TYPE OF TECHNOLOGY, THROUGH JUNE 15, 2011 (PERCENT OF U.S. PATENTS ISSUED) TABLE 8 U.S. CHARGED PARTICLE MICROSCOPY PATENTS AND PATENT APPLICATIONS, THROUGH JUNE 15, 2011 (NUMBER AND PERCENT OF U.S. PATENTS) Trends Over Time TABLE 9 CHARGED PARTICLE MICROSOCOPY PATENTS ISSUED ANNUALLY, BY TYPE OF TECHNOLOGY, (NUMBER OF PATENTS) FIGURE 21 CHARGED PARTICLE MICROSCOPY PATENTS ISSUED ANNUALLY, BY TYPE OF TECHNOLOGY, (NUMBER OF PATENTS) FIGURE 21 (CONTINUED) Patent Holders TABLE 10 CHARGED PARTICLE MICROSCOPY PATENT HOLDERS, THROUGH JUNE 15, 2011 (NUMBER OF PATENTS ISSUED) FIGURE 22 CHARGED PARTICLE MICROSCOPE PATENT HOLDERS, THROUGH JUNE 15, 2011 (% OF TOTAL PATENTS ISSUED) FIGURE 23 MAJOR CHARGED PARTICLE MICROSCOPY PATENT HOLDERS, BY TECHNOLOGY TYPE (PERCENT OF TOTAL PATENTS) TABLE 11 MAJOR CHARGED PARTICLE MICROSCOPY PATENT HOLDERS, BY TECHNOLOGY TYPE (NUMBER OF PATENTS) Manufacturers TABLE 12 CHARGED-PARTICLE MICROSCOPE MANUFACTURERS SCANNING-PROBE MICROSCOPES Description and Applications FIGURE 24 SCANNING PROBE MICROSCOPE TABLE 13 TYPES AND PRIMARY APPLICATIONS OF SCANNING PROBE MICROSCOPES Scanning Tunneling Microscopes Atomic Force Microscopes FIGURE 25 ATOMIC FORCE MICROSCOPE PROBE Other Types of Scanning Probe Microscope Magnetic Force Microscopes Electric Force Microscopes Scanning Thermal Microscopy... 69

5 Patent Analysis Technologies TABLE 14 U.S. SCANNING PROBE MICROSCOPY PATENTS FIGURE 26 SCANNING PROBE MICROSCOPY PATENTS, BY TYPE OF TECHNOLOGY, AS OF JUNE 15, 2011 (PERCENT OF TOTAL PATENTS) Trends Over Time TABLE 15 SCANNING PROBE MICROSCOPY PATENTS ISSUED ANNUALLY, BY TYPE OF TECHNOLOGY, (NUMBER OF PATENTS) FIGURE 27 SCANNING PROBE MICROSCOPY PATENTS ISSUED ANNUALLY, BY TYPE OF TECHNOLOGY, (NUMBER OF PATENTS ISSUED ANNUALLY) Patent Holders TABLE 16 SCANNING PROBE MICROSCOPY PATENT HOLDERS AND APPLICANTS FIGURE 28 SCANNING PROBE MICROSCOPE PATENT HOLDERS, THROUGH JUNE 15, 2011 (PERCENT OF TOTAL U.S. PATENTS ISSUED) TABLE 17 SCANNING PROBE MICROSCOPY PATENT HOLDERS, BY TECHNOLOGY TYPE (NUMBER OF PATENTS) FIGURE 29 MAJOR SPM PATENT HOLDERS, BY TECHNOLOGY TYPE (PERCENT OF TOTAL PATENTS) FIGURE 29 (CONTINUED) Manufacturers TABLE 18 SCANNING PROBE MICROSCOPE MANUFACTURERS ACCESSORIES AND SUPPLIES Description and Applications TABLE 19 MICROSCOPE ACCESSORIES AND THEIR MAIN FUNCTIONS Photomicroscopy Equipment Illumination Systems Microscope Stages and Accessories Eyepieces Objectives Scanning Probes Consumables Patent Analysis Accessory Types TABLE 20 U.S. MICROSCOPE ACCESSORY PATENTS FIGURE 30 U.S. MICROSCOPE ACCESSORY PATENTS, BY ACCESSORY TYPE, AS OF JUNE 15, 2011 (PERCENT OF TOTAL PATENTS ISSUED)... 80

6 TABLE 21 MICROSCOPE ACCESSORY PATENT HOLDERS AND APPLICANTS, THROUGH JUNE 15, FIGURE 31 MICROSCOPE ACCESSORY PATENT HOLDERS, THROUGH JUNE 15, 2015 (PERCENT OF PATENTS ISSUED) Manufacturers TABLE 22 MICROSCOPE ACCESSORY MANUFACTURERS END USERS TABLE 23 MICROSCOPE END-USER INDUSTRIES SEMICONDUCTORS Optical Microscopes Charged Particle Microscopes Scanning Probe Microscopes PHOTOVOLTAICS LIFE SCIENCES TABLE 24 GLOBAL LIFE SCIENCES SALES, 2010 ($ BILLIONS) Optical Microscopes Charged Particle Microscopes MATERIALS SCIENCE FIGURE 32 MATERIALS SCIENCE INSTRUMENTS, MAJOR MARKET SEGMENTS, 2010 (PERCENT OF TOTAL SALES) Optical Microscopes Charged Particle Microscopes Scanning Probe Microscopes NANOTECHNOLOGY Charged Particle Microscopes Scanning Probe Microscopes OTHER END USERS Education Optical Microscopes Other Types of Microscopes Environmental Science Optical Microscopes Charged Particle Microscope Forensics Optical Microscopes Charged Particle Microscopes Food Processing Optical Microscopes Charged Particle Microscopes CHAPTER FOUR: GLOBAL MARKET FOR MICROSCOPES AND ACCESSORIES 2010 TO OVERALL MARKET SIZE AND SEGMENTATION... 96

7 FIGURE 33 TRENDS IN GLOBAL SALES OF MICROSCOPES AND ACCESSORIES/ SUPPLIES, (ANNUAL SALES, $ MILLIONS) DETAILED MARKET ANALYSIS AND PROJECTIONS MARKET BY TYPE OF INSTRUMENT TABLE 25 PROJECTED GLOBAL MICROSCOPE SALES BY PRODUCT TYPE, THROUGH 2016 ($ MILLION) FIGURE 34 MICROSCOPY MAJOR MARKET SEGMENTS, 2010 VERSUS 2016 (%) Optical Microscopes Optical Microscope Market Size and Segmentation TABLE 26 OPTICAL MICROSCOPE SALES, 2010 ($ MILLIONS/%) FIGURE 35 OPTICAL MICROSCOPE MARKET SEGMENTATION, 2010 (% OF TOTAL OPTICAL MICROSCOPE SALES) Market Drivers Spending on Educational Equipment TABLE 27 U.S. EDUCATIONAL EXPENDITURES, ($ BILLIONS) FIGURE 36 TRENDS IN U.S. EDUCATIONAL EXPENDITURES, ($ BILLIONS) Trends in Infrared Spectroscopy TABLE 28 GLOBAL MOLECULAR SPECTROMETRY SALES, THROUGH 2016 ($ BILLIONS) Life Sciences R&D and Healthcare Spending TABLE 29 LIFE SCIENCES R&D SPENDING, THROUGH 2016 ($ BILLIONS) FIGURE 37 TRENDS IN LIFE SCIENCES R&D SPENDING, ($ BILLIONS) Materials Science Instrument Spending TABLE 30 GLOBAL SPENDING ON MATERIALS CHARACTERIZATION INSTRUMENTS, THROUGH 2016 ($ BILLIONS) FIGURE 38 MATERIALS CHARACTERIZATION INSTRUMENT SALES TRENDS, ($ BILLIONS) Technology Shift Away From Compound Optical Microscopy Future Market for Optical Microscopes TABLE 31 PROJECTED SALES OF OPTICAL MICROSCOPES, THROUGH 2016 ($ MILLIONS) TABLE 32 PROJECTED GROWTH RATE OF MARKET FOR STEREOSCOPIC MICROSCOPES, THROUGH 2016 (PERCENT CAGR)

8 TABLE 33 PROJECTED GROWTH RATE OF MARKET FOR SCANNING NEAR-FIELD OPTICAL MICROSCOPES, THROUGH 2016 (PERCENT CAGR) FIGURE 39 OPTICAL MICROSCOPE MARKET SEGMENTATION, 2016 (%) FIGURE 39 (CONTINUED) Charged Particle Microscopes Charged Particle Microscope Market Size and Segmentation TABLE 34 CHARGED PARTICLE MICROSCOPE SALES, 2010 ($ MILLIONS/%) FIGURE 40 CHARGED PARTICLE MICROSCOPE MARKET SEGMENTS, 2010 (%) Market Drivers Semiconductor Industry Investment Trends FIGURE 41 MARKETS FOR SCANNING ELECTRON MICROSCOPES, 2010 (PERCENT OF TOTAL SEM SALES) TABLE 35 SEMICONDUCTOR INDUSTRY CAPITAL EQUIPMENT SPENDING PROJECTIONS, THROUGH 2016 ($ BILLIONS) FIGURE 42 PROJECTED GROWTH IN SEMICONDUCTOR CAPITAL EQUIPMENT SPENDING, ($ BILLIONS) Technology Shifts FIGURE 43 CHARGED PARTICLE MICROSCOPE SALES GROWTH VERSUS GROWTH IN MAJOR UNDERLYING MARKETS, (%) Future Market for Charged Particle Microscopes TABLE 36 PROJECTED SALES OF CHARGED PARTICLE MICROSCOPES, THROUGH 2016 ($ MILLIONS) TABLE 37 PROJECTED GROWTH RATE OF SCANNING ELECTRON MICROSCOPE SALES TO THE LIFE AND MATERIALS SCIENCES, THROUGH 2016 ($ MILLIONS) FIGURE 44 CHARGED PARTICLE MICROSCOPE MARKET SEGMENTS, 2016 (PERCENT OF TOTAL SALES) Scanning Probe Microscopes Scanning Probe Microscope Market Size and Segmentation FIGURE 45 SPM MARKET PRODUCT SEGMENTS, 2010 (%) Market Drivers Trends in Nanoscale Applications Technology Shifts Future Market for Scanning Probe Microscopes TABLE 38 PROJECTED SALES OF SCANNING PROBE MICROSCOPES, THROUGH 2016 ($ MILLIONS)

9 FIGURE 46 SCANNING PROBE MICROSCOPE MARKET SEGMENTS, 2016 (PERCENT OF TOTAL SALES) Accessories and Supplies Market Size and Segmentation TABLE 39 SALES OF MICROSCOPE ACCESSORIES AND CONSUMABLES, 2010 ($ MILLIONS/%) FIGURE 47 MICROSCOPE ACCESSORIES AND SUPPLIES MARKET SEGMENTATION, 2010 (%) Market Drivers Number of Microscopes in Use Worldwide TABLE 40 NUMBER OF MICROSCOPES IN USE WORLDWIDE, THROUGH 2016 (MILLION UNITS) FIGURE 48 TRENDS IN NUMBER OF MICROSCOPES IN USE WORLDWIDE, (MILLION UNITS) Future Markets for Microscope Accessories and Supplies TABLE 41 PROJECTED SALES OF MICROSCOPE ACCESSORIES AND SUPPLIES, THROUGH 2016 ($ MILLIONS) MARKETS BY END-USER SEGMENT Optical Microscopes FIGURE 49 OPTICAL MICROSCOPE MARKET SHARES, BY END- USER SEGMENT, 2010 VERSUS 2016 (%) TABLE 42 END-USER MARKETS FOR OPTICAL MICROSCOPES THROUGH 2016 ($ MILLIONS) Charged Particle Microscopes TABLE 43 END-USER MARKETS FOR CHARGED PARTICLE MICROSCOPES, THROUGH 2016 ($ MILLIONS) FIGURE 50 CHARGED PARTICLE MICROSCOPE MARKET SHARES BY END-USER SEGMENT, 2010 VERSUS 2016 (%) Scanning Probe Microscopes All Types of Microscopes TABLE 44 END-USER MARKETS FOR ALL TYPES OF MICROSCOPES, THROUGH 2016 ($ MILLIONS) FIGURE 51 MICROSCOPE MARKET SHARES BY END-USER SEGMENT, 2010 VERSUS 2016 (%) GEOGRAPHICAL MARKETS Optical Microscopes TABLE 45 GEOGRAPHICAL MARKETS FOR OPTICAL MICROSCOPES, THROUGH 2016 ($ MILLIONS) FIGURE 52 OPTICAL MICROSCOPE GEOGRAPHICAL MARKET SHARES 2010 VERSUS 2016 (PERCENTAGE OF GLOBAL SALES) Charged Particle Microscopes TABLE 46 GEOGRAPHICAL MARKETS FOR CHARGED PARTICLE MICROSCOPES, THROUGH 2016 ($ MILLIONS)

10 FIGURE 53 CHARGED PARTICLE MICROSCOPE GEOGRAPHICAL MARKET SHARES, 2010 VERSUS 2016 (PERCENTAGE OF GLOBAL SALES) Scanning Probe Microscopes TABLE 47 GEOGRAPHICAL MARKETS FOR SCANNING PROBE MICROSCOPES 2010 THROUGH 2016 ($ MILLIONS) FIGURE 54 SCANNING PROBE MICROSCOPE GEOGRAPHICAL MARKET SHARES, 2010 VERSUS 2016 (PERCENTAGE OF GLOBAL SALES) All Types of Microscopes TABLE 48 GEOGRAPHICAL MARKETS FOR ALL TYPES OF MICROSCOPES THROUGH FIGURE 55 MICROSCOPE MARKET SHARES BY END-USER SEGMENT 2010 VERSUS 2016 (%) CHAPTER FIVE: INDUSTRY STRUCTURE MARKET SHARES OPTICAL MICROSCOPES FIGURE 56 OPTICAL MICROSCOPY MARKET SHARES, 2010 (PERCENT OF TOTAL SALES, BY VALUE) FIGURE 56 (CONTINUED) CHARGED PARTICLE MICROSCOPES Electron Microscopes FIGURE 57 ESTIMATED ELECTRON MICROSCOPE MARKET SHARES, 2010 (PERCENT OF TOTAL SALES BY VALUE) FIGURE 57 (CONTINUED) Focused Ion Beam Microscopes FIGURE 58 FOCUSED ION BEAM MICROSCOPE MARKET SHARES, 2010 (PERCENT OF TOTAL SALES, BY VALUE) SCANNING PROBE MICROSCOPES FIGURE 59 SCANNING PROBE MICROSCOPE MARKET SHARES, 2010 (ESTIMATED PERCENT OF TOTAL SALES, BY VALUE) OWNERSHIP TRENDS OWNERSHIP TRENDS (CONTINUED) OWNERSHIP TRENDS (CONTINUED) CHAPTER SIX: COMPANY PROFILES APPLIED MATERIALS, INC BRUKER AXS BRUKER OPTICS INC BUEHLER INC CAMECA SA DANISH MICRO ENGINEERING A/S FEI COMPANY GATAN, INC

11 HITACHI HIGH TECHNOLOGIES CORP JASCO INTERNATIONAL CO. LTD JEOL LTD LEICA MICROSYSTEMS AG MIS INC NANONICS IMAGING LTD NANOSURF AG NIKON CORP NT-MDT CO OBDUCAT-CAMSCAN LTD OLYMPUS CORPORATION OMICRON NANOTECHNOLOGY GMB PERKIN ELMER, INC PARK SYSTEMS CORP QUESANT INSTRUMENT CORPORATION QUESTAR CORP SCHOTT NORTH AMERICA INC SHIMADZU CORP SII NANOTECHNOLOGY INC THERMO FISHER SCIENTIFIC INC VEECO INSTRUMENTS INC WITEC WISSENSCHAFTLICHE INSTRUMENTE UND TECHNOLOGIE GMBH CARL ZEISS NTS GMBH