why advertise in the lancet?

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1 why advertise in the lancet? display advertising rates The Lancet is the world s leading independent general medical journal and has been published weekly since The journal has an international scope and its coverage extends across all aspects of human health. Only ground-breaking, original, primary research papers, and review articles of the highest standard make it through The Lancet s stringent peer-review process. This ensures the continuing scientific merit and clinical relevance of its diverse content. This blend of challenging editorials, signed commentaries, original research, commissioned reviews, international news, and the views of readers in the letters pages make The Lancet an essential weekly read for physicians all over the world. The Lancet has a dedicated career opportunities section as well as web advertising, sponsorship opportunities and review journals which focus on specific therapy areas such as oncology, neurology and infectious diseases. Our readers are the most influential physicians in the world and, with an average subscription duration of over 17 years, it is clear that The Lancet commands trust and respect from our readers in the worldwide medical community. one insertion region cost double page spread uk only 2,430 four colour row 2,673 usa 4,689 global 10,800 full page uk only 1,350 four colour row 1,485 usa 2,605 global 6,000 half page uk only 888 Colour row 968 usa 1,675 global 3,825 full page uk only 935 mono row 1,030 usa 1,775 global 4,100 special positions outside back cover +30% inside front cover +20% inside back cover +10% series discounts 3 6 insertions 4% 7 11 insertions 8% 12+ insertions POA agency discount 10% advertisement deadline: 10 days prior to cover date. The Lancet is published every Saturday. All bookings are subject to The Lancet conditons of acceptance.

2 about our readers reader profile 90% of subscribers trust The Lancet to keep them informed of changes in world medicine Our average subscription length is 17 years 69% influence the purchase of medical equipment in their workplace 88% of subscribers are medically qualified 82% are hands-on clinicians 65% attend up to 7 conferences per year 60% as a result of The Lancet s Conference listing Over half of The Lancet s readers have acted as a result of an advertisement 76% of subscribers use The Lancet for career opportunities the lancet profile from subscriber survey The Lancet s Global Reach Print Edition qualified circulation by region circulation 29,103 circulation statement: December bpa 2007 Split runs available on request Registered users on thelancet.com Over 1.8 million registered users worldwide on 1 Over 83,000 E-ToC subscribers (weekly) 2 1,2 publishers statement For further information, bookings and to send artwork, please : Sarah Jane Cahill Business Development Executive Tel +44 (0) sarah.cahill@lancet.com Martin Sibson Tel +44 (0) m.sibson@elsevier.com

3 reprints and e-prints Do you need to share important information with your clients? The Lancet reprints service offers you the answer providing a full reprint of any original article appearing in The Lancet, or it s sister publications, which you can hand to your clients, salesforce or shareholders. Add authority to your existing product literature and help to establish and develop your market position. Full reprint service provided: Guaranteed integrity of information through The Lancet branding, full bibliographic details including all references, and the high-quality printing and finish you find in the weekly journal Standard printing up to 10 working days Express printing available maximum of 3 working days Opportunity to feature your company logo on the front or cover Translation into any language Minimum order of 100, with no maximum volume discounts mean the more you order the more cost effective it becomes Combined reprints a selection of The Lancet papers of your choice in one handy document E-prints service also available providing you with a PDF file you can place on your own website, or for distribution E-prints The Lancet E-prints can be posted on your website and accessed by chosen clients on a password basis providing fast, easy access to information. For further information on The Lancet reprint and e-print service, please : John Fyfe Business Development Executive Tel +44 (0) j.fyfe@elsevier.com

4 sponsorship opportunities Sponsored subscriptions to The Lancet provide a unique opportunity to keep your target groups of clinicians updated on international medical news and research, while promoting your current products. Sponsored subscriptions are delivered direct to the chosen recipient on your behalf and they provide you with exclusive promotional opportunities. Sponsored subscriptions are available for all four journals at specially discounted rates. Commissioned research studies* carried out amongst physicians in receipt of a sponsored complimentary subscription to The Lancet found that: 1 Nine out of ten receivers of The Lancet found the complimentary subscription valuable to their practice and wished to continue receiving it. 2 Three quarters of all respondents were aware that their subscription to The Lancet was sponsored by a pharmaceutical company. Moreover, one half also recalled, on an unaided basis, the name of the sponsoring company. 3 Six out of ten participants remembered unaided that the cover wrap on their issue of The Lancet displayed an advertisement for Product A % of the physicians who recalled seeing Product A on the cover wrap, were aware of its uses and indications prior to receiving complimentary subscription. 5 One third of the physicians who recalled seeing Product A took one or more favourable actions towards Product A in response to reading its message. These actions included prescribing the product, discussing it with a product representative or colleague and seeking more information about the product. *from subscription evaluation study, nov 2003, conducted by matalia group, inc. For further information, please : Sarah Cahill Tel +44 (0) Fax +44 (0) s.cahill@elsevier.com

5 display advertising specifications Advertising copy must be supplied digitally to the specifications below. mechanical data (all sizes in mm) size depth width digital specifications Our preferred method of supply is as a PDF created using Acrobat Distiller Version 5.0. PDF files to be supplied as composite CMYK. Files must be supplied as single pages. Pages must be created to include bleed when required. Crop marks must be outside the bleed area. A 3mm offset is recommended. Files must contain all images in high-resolution, CMYK format and have all fonts embedded. flightchecking All files must be run through an agreed flightchecking application before transmission, to ensure file and colour integrity. (The flightchecker must ensure the following: Acrobat 3.0 compatibility. Image resolution 300 dpi (min). All fonts embedded. Colour is CMYK). Content of digital files must be verified fore transmission and all relevant graphics and fonts must be included. The file content remains the responsibility of the sender supplying files If supplying files on disc, please use industry standard CD-ROM. Media must be write - protected and contain only the file required for each advertisement. If a disc is being supplied it should be clearly labelled with identification information indicating client, headline, journal, issue and originator s details. Files may be transmitted via ISDN, with prior arrangement: +44 (0) An confirming the sending of any digital advert should be sent prior to transmission and should contain the identification information as specified. hard copy proofs All digital files submitted must be accompanied by a proof. We require 100% of final size, customer approved colour contract proofs. Acceptable proofs are: Fuji First Proof, Scitex Iris, Imation Rainbow, Kodak Approval, DuPont Digital Cromalin. The Lancet cannot accept responsibility for colour reproduction if one of the above colour proofs is not supplied. Please use URN; LANCET + your booking order ref type area full page double page spread trim marks whole page double page spread bleed whole page double page spread For further information, bookings and to send artwork, please : Sarah Jane Cahill Business Development Executive Tel +44 (0) sarah.cahill@lancet.com or Martin Sibson Business Development Executive Tel +44 (0) m.sibson@elsevier.com

6 terms and conditions Advertising orders are subject to written confirmation and will only be accepted on condition that the advertiser warrants that the advertisements supplied do not contravene the Trade Description Act 1968, the Race Relations Act 1968 or the ABPI Code of Practice/FDA Guidelines. Accounts are strictly net and are subject to satisfactory reference. All invoices must be settled within 30 days of receipt. All copy is subject to the approval of the publishers. The publishers reserve the right to reject any advertisement not of direct interest to the readership or not in keeping with the scientific and ethical standards of the publication. Cancellations must be received in writing no later than six weeks before publication date. Advertisers failing to comply with these requirements will be liable for payment of the full space booked. If the advertiser cancels part of the series booking, all unearned discounts will be surcharged. If the copy instructions have not been received by the stated deadline, existing material may be repeated and the advertisers will be liable for payment of the full space booked. Advertiser s material is held at the owner s risk and should be insured by them against fire, loss or damage. Material will be held for twelve months and then destroyed unless return is requested. The publishers will not be liable for any loss occasioned by the failure of any advertisement to appear, nor do they accept liability for printer s errors, although every care is taken to avoid mistakes. All freight and import charges incurred in sending material for publication and all costs incurred because of failure to comply with mechanical specifications will be charged to the advertiser. The advertiser will indemnify and protect the publishers from any claims or actions against them arising from unauthorised, inaccurate or libellous statements appearing in advertising material.

7 Neurology display advertising information Since its launch in March 2002, The Lancet Neurology has already built an impressive reputation for its outstanding review content, becoming a must-read journal for neurologists. It is this great reputation and high profile which has now allowed The Lancet Neurology to extend its scope to include original primary research for the first time from its October 2005 issue. However, in addition to publishing the cream of new research in the field, The Lancet Neurology will continue to provide neurology specialists with clear and concise reviews examining the most important recent advances with the greatest and most immediate impact on clinical practice. The Lancet s global reporting capabilities ensure that The Lancet Neurology provides the most important and current international news from this vast specialty; its two news sections, Newsdesk and Media Watch ensure that it responds rapidly to international developments in neurology with great precision. The Lancet Neurology is the first place neurologists look when researching respected opinions, news and reviews or being updated on the latest in clinical trials. It is also the perfect place to advertise your neurology career opportunities and services. The Website Combining print advertising with electronic advertising opportunities on The Lancet Neurology website provides advertisers with access to a vast new audience. The Lancet Neurology website contains the latest table of contents, abstracts, accepted papers, instructions for authors and more: display advertising rates frequency cost double page spread x1 month 2,005 x3 month 1,856 x6 month 1,790 x12 month 1,485 full page four colour x1 month 1,432 x3 month 1,326 x6 month 1,220 x12 month 1,061 half page four colour x1 month 902 special positions x3 month 835 x6 month 770 x12 month 669 outside back cover +20% inside front cover +15% inside back cover +10% first right-hand page +10% discounts agency discount 10% circulation Worldwide 4,492 BPa DEC 2007 Split runs available on request The Lancet Neurology is published monthly All bookings are subject to The Lancetconditions of acceptance.

8 Neurology display advertising specifications Advertising copy must be supplied digitally to the specifications below. mechanical data (all sizes in mm) size depth width digital specifications Our preferred method of supply is as a PDF created using Acrobat Distiller Version 5.0. PDF files to be supplied as composite CMYK. Files must be supplied as single pages. Pages must be created to include bleed when required. Crop marks must be outside the bleed area. A 3mm offset is recommended. Files must contain all images in high-resolution, CMYK format and have all fonts embedded. flightchecking All files must be run through an agreed flightchecking application before transmission, to ensure file and colour integrity. (The flightchecker must ensure the following: Acrobat 3.0 compatibility. Image resolution 300 dpi (min). All fonts embedded. Colour is CMYK). Content of digital files must be verified before transmission and all relevant graphics and fonts must be included. The file content remains the responsibility of the sender. supplying files If supplying files on disc, please use industry standard CD-ROM. Media must be write - protected and contain only the file required for each advertisement. If a disc is being supplied it should be clearly labelled with identification information indicating client, headline, journal, issue and originator s details. Files may be transmitted via ISDN, with prior arrangement: +44 (0) An confirming the sending of any digital advert should be sent prior to transmission and should contain the identification information as specified. hard copy proofs All digital files submitted must be accompanied by a proof. We require 100% of final size, customer approved colour contract proofs. Acceptable proofs are: Fuji First Proof, Scitex Iris, Imation Rainbow, Kodak Approval, DuPont Digital Cromalin. The Lancet cannot accept responsibility for colour reproduction if one of the above colour proofs is not supplied. type area full page double page spread trim marks whole page double page spread bleed whole page double page spread For further information, bookings and to send artwork, please : Martin Sibson Tel +44 (0) m.sibson@elsevier.com

9 Infectious Diseases why advertise in the lancet infectious diseases? display advertising rates The Lancet Infectious Diseases provides ID specialists with all the information that they need in a clear, concise and readable format. Each month The Lancet Infectious Diseases reviews the most recent research, highlighting those advances with the greatest and most immediate impact on clinical practice. The Lancet s global reporting capabilities ensures that The Lancet Infectious Diseases provides the most important and current international news from this vast specialty.. For our advertisers, this perfect-bound, high-profile journal provides an excellent platform from which to advertise. In print and online The Lancet Infectious Diseases provides you, our advertisers, with a first class media solution which rivals anything available in medical publishing. The Lancet Infectious Diseases is a must-read for ID specialists worldwide. The Website Combining print advertising with electronic advertising opportunities on The Lancet Infectious Diseases website provides advertisers with access to a vast new audience. The Lancet Infectious Diseases website contains the latest table of contents, abstracts, accepted papers, instructions for authors and more: frequency cost double page spread x1 month 2,005 x3 month 1,856 x6 month 1,790 x12 month 1,485 full page four colour x1 month 1,432 x3 month 1,326 x6 month 1,220 x12 month 1,061 half page four colour x1 month 902 x3 month 835 x6 month 770 x12 month 669 special positions outside back cover +50% inside front cover +25% inside back cover +25% first right-hand page +20% first double-page spread +20% discounts agency discount 10% CIRCULATION Worldwide 1,650 BPA DEC 2007 Split runs available on request The Lancet Infectious Diseases is published monthly. All bookings are subject to The Lancet conditions of acceptance.

10 Infectious Diseases display advertising specifications Advertising copy must be supplied digitally to the specifications below. mechanical data (all sizes in mm) size depth width digital specifications Our preferred method of supply is as a PDF created using Acrobat Distiller Version 5.0. PDF files to be supplied as composite CMYK. Files must be supplied as single pages. Pages must be created to include bleed when required. Crop marks must be outside the bleed area. A 3mm offset is recommended. Files must contain all images in high-resolution, CMYK format and have all fonts embedded. supplying files If supplying files on disc, please use industry standard CD-ROM. Media must be write - protected and contain only the file required for each advertisement. If a disc is being supplied it should be clearly labelled with identification information indicating client, headline, journal, issue and originator s details. Files may be transmitted via ISDN, with prior arrangement: +44 (0) An confirming the sending of any digital advert should be sent prior to transmission and should contain the identification information as specified. type area full page double page spread trim marks whole page double page spread bleed whole page double page spread flightchecking All files must be run through an agreed flightchecking application before transmission, to ensure file and colour integrity. (The flightchecker must ensure the following: Acrobat 3.0 compatibility. Image resolution 300 dpi (min). All fonts embedded. Colour is CMYK). Content of digital files must be verified before transmission and all relevant graphics and fonts must be included. The file content remains the responsibility of the sender. hard copy proofs All digital files submitted must be accompanied by a proof. We require 100% of final size, customer approved colour contract proofs. Acceptable proofs are: Fuji First Proof, Scitex Iris, Imation Rainbow, Kodak Approval, DuPont Digital Cromalin. The Lancet cannot accept responsibility for colour reproduction if one of the above colour proofs is not supplied. For further information, bookings and to send artwork, please : Martin Sibson Tel +44 (0) m.sibson@elsevier.com

11 Oncology why advertise in the lancet oncology? The aim of The Lancet Oncology is to publish interesting and informative research on any topic connected with oncology. The journal s great reputation and high profile allowed it to extend into the field of primary research from May Published monthly The Lancet Oncology provides oncology specialists with insightful editorial comment and opinion pieces from influential figures. The Lancet Oncology s excellent reputation ensures that we can afford to publish only the best reviews and research on topics spanning all oncology related fields. We are therefore viewed as a must-read journal by clinicians, laboratory scientists and policy makers who value the far-reaching content to help guide their decision making. Advertising in The Lancet Oncology will ensure that your message reaches around 4,500 respected oncology professionals including clinicians specialising in chemotherapy, radiotherapy and surgery, care givers and students. For our advertisers, this perfect-bound, full colour journal provides the ideal platform to advertise your oncology career opportunities and services to a targeted audience of around 4,500 oncologists worldwide. The Website Combining print advertising with electronic advertising opportunities on The Lancet Oncology website provides advertisers with access to a vast new audience. The website also contains the latest table of contents, abstracts, accepted papers, instructions for authors and more: display advertising rates frequency cost double page spread x1 month 2,920 four colour x3 month 2,844 x6 month 2,775 x12 month 2,699 full page four colour x1 month 1,839 x3 month 1,763 x6 month 1,693 x12 month 1,617 full page mono pi only 624 half page mono pi only 364 UK only 1,275 special positions outside back cover +50% inside front cover +25% inside back cover +10% first right-hand page +20% discounts agency discount 10% split-runs available for advertisers; UK/Europe/USA/ ROW circulation worldwide 1691 bpa Dec 2007 The Lancet Oncology is published monthly. All bookings are subject to The Lancet conditions of acceptance.

12 Oncology display advertising specifications Advertising copy must be supplied digitally to the specifications below. mechanical data (all sizes in mm) size depth width digital specifications Our preferred method of supply is as a PDF created using Acrobat Distiller Version 5.0. PDF files to be supplied as composite CMYK. Files must be supplied as single pages. Pages must be created to include bleed when required. Crop marks must be outside the bleed area. A 3mm offset is recommended. Files must contain all images in high resolution,cmyk format and have all fonts embedded. If supplying files on disc, please use industry standard CD-ROM. Media must be write -protected and contain only the file required for each advertisement. If a disc is being supplied it should be clearly labelled with identification information indicating client, headline, journal, issue and originator s details. Files may be transmitted via ISDN, with prior arrangement: +44 (0) An confirming the sending of any digital advert should be sent prior to transmission and should contain the identification information as specified. type area full page double page spread trim marks whole page double page spread bleed whole page double page spread flightchecking All files must be run through an agreed flightchecking application before transmission, to ensure file and colour integrity. (The flightchecker must ensure the following: Acrobat 3.0 compatibility. Image resolution 300 dpi (min). All fonts embedded. Colour is CMYK). Content of digital files must be verified before transmission and all relevant graphics and fonts must be included. The file content remains the responsibility of the sender. supplying files hard copy proofs All digital files submitted must be accompanied by a proof. We require 100% of final size, customer approved colour contract proofs. Acceptable proofs are: Fuji First Proof, Scitex Iris, Imation Rainbow, Kodak Approval, DuPont Digital Cromalin. The Lancet cannot accept responsibility for colour reproduction if one of the above colour proofs is not supplied. For further information, bookings and to send artwork, please : Sarah Cahill Tel +44 (0) Fax +44 (0) s.cahill@elsevier.com

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