Workshop on Oral cgvhd & Clinical practice in cgvhd

Falk Workshop Workshop on Oral cgvhd & Clinical practice in cgvhd University Hospital, Registration: Friday, November 22, 2013 7.00 19.00 h at the congress office Scientific Organization (): R. Andreesen E. Holler J. Meier T. E. Reichert D. Wolff Congress Venue: University Hospital Franz-Josef-Strauss-Allee 11 93053 Information: Prof. Dr. Daniel Wolff Department of Hematology and Oncology University Hospital Franz-Josef Strauss-Allee 11 93053 Tel: +49 (0)941-944-5531 Fax: +49 (0)941-944-5543 E-Mail: daniel.wolff@ukr.de Official Language: English 5 107184_Falk WS_Prog_Inhalt.indd 5 14.02.13 10:03

Preface... 4 Scientific Program......................... 6 List of Speakers... 9 Information... 13 CME credits for the Falk Workshop have been applied for at the European Union of Medical Specialists (UEMS). 3 107184_Falk WS_Prog_Inhalt.indd 3 14.02.13 10:03

Preface Dear Colleagues, We are pleased to invite you to the Workshop on Oral cgvhd & Clinical Practice in cgvhd 2013 held in. Chronic GVHD continues to be a challenge in clinical practice balancing GVHD treatment against toxicity and infectious morbidity. The workshop will focus on two aspects in clinical care of patients with chronic GVHD. The workshop on oral GVHD will provide a comprehensive overview on pathophysiology, diagnosis, immunosuppressive and supportive treatment as well as long term complications of oral chronic GVHD. The workshop on clinical practice of chronic GVHD will focus on daily routine and will be organized in case seminars in small groups each headed by a multidisciplinary team (Senior Transplant Physician, Pathologist, Dermatologist, Oral Surgeon, Physical Therapist, Ophthalmologist, Transplant Nurse). Additional specialties will be added if required. The aim is to evaluate patients with chronic GVHD including diagnosis, pathology, severity grading, and to discuss treatment options, to develop a treatment plan including supportive care. Since different groups will evaluate the same patients, this approach will permit the indentification of areas of consensus as well as fields with further need of clarification. In contrast to the last meetings where will be fields with further need of clarification. In contrast to the last meetings where will be an upper limit for pariticipants during the workshops at saturday. Both workshops are supported by Falk Foundation e.v. E. Holler, M. Edinger, J. Meier, T.E. Reichert, E. Huber, D. Wolff () H. Greinix, A. Lawitschka (Vienna) J. Halter (Basel) 4 107184_Falk WS_Prog_Inhalt.indd 4 14.02.13 10:03

Friday, November 22, 2013 Workshop on Oral cgvhd Introduction Chair: W. Herr, Mainz; W. Wagner, Mainz 8.30 Introduction E. Holler, T. E. Reichert, 8.45 Pathophysiology of oral cgvhd J. Meier, 9.15 Proteomics in oral cgvhd J. W. Mays, Bethesda 9.30 Histopathology of oral cgvhd M. Imanguli, Dallas 9.50 Clinical manifestations and diagnosis of oral cgvhd S. Elad, Rochester Coffee break Immunosuppressive treatment of oral cgvhd Chair: F. Ayuk, Hamburg; S. Elad, Rochester 10.45 Topical steroids S. Elad, Rochester 11.10 Topical calcineurin-inhibitors M. Albert, Munich 11.25 Oral PUVA and UVB N. S. Treister, Boston 11.40 Systemic treatment H. Greinix, Vienna 12.00 Lunch break 6 107184_Falk WS_Prog_Inhalt.indd 6 14.02.13 10:03

Friday, November 22, 2013 Supportive care of oral cgvhd Chair: R. G. Meyer, Mainz; N. S. Treister, Boston 12.45 Supportive care E. M. Wagner, Mainz 13.05 Laser treatment of oral cgvhd J. Meier, 13.20 Paediatric aspects A. Lawitschka, Vienna 13.40 Treatment of oral sclerosis N. S. Treister, Boston 13.55 Dental issues in oral GVHD S. Hahnel, 14.10 Secondary malignancies in oral GVHD T. E. Reichert, 14.30 Conclusion Chair: S. Elad, Rochester; J. W. Mays, Bethesda; J. Meier, ; T. E. Reichert, ; N.S. Treister, Boston; D. Wolff, 12.00 15.00 Meeting of pathology groups (Institute of Pathology) Workshop on Clinical Practice cgvhd Current concepts in clinical care of cgvhd Chair: J. Halter, Basel; S. Z. Pavletic, Bethesda 15.45 Pathophysiology of cgvhd E. Holler, 16.15 Diagnosis of cgvhd H. Greinix, Vienna 16.45 Histopathology of cgvhd E. Huber, 17.15 Coffee break 17.30 Response evaluation of cgvhd S. Lee, Seattle 18.00 Treatment of cgvhd D. Wolff, 18.30 Supportive care H. Bertz, Freiburg 7 107184_Falk WS_Prog_Inhalt.indd 7 14.02.13 10:03

Saturday, November 23, 2013 Workshop on clinical practice in cgvhd 8.30 Introduction and Instruction Chair: S. Lee, Seattle; D. Wolff, 9.00 First part of the Workshop (3 patients per group) 12.00 Lunch 12.45 Second part of the Workshop (3 patients per group) 15.45 Coffee break 16.00 Conclusions GVHD teams are headed by: H. Greinix, Vienna; S. Z. Pavletic, Bethesda; S. Lee, Seattle; J. Halter, Basel; E. Holler, ; F. Ayuk Hamburg The GVHD teams are supported by: Pathology: H. A. Baba, Essen; E. Huber, ; A. Kreft, Mainz; F. Länger, Hannover; T. Longerich, Heidelberg; A. Tzankow, Basel Dermatology: P. Häusermann, Basel; U. Hillen, Essen; U. Just, Vienna; C. Marks, Freiburg; E. von Stebut-Borschitz, Mainz; M. Ziemer, Leipzig Ophthalmology: C. Blecha, ; T. Dietrich, ; P. Eberwein, Freiburg; D. Goldblum, Basel; T. Meyer-ter-Vehn, Würzburg; H. Westekemper, Essen Oral Medicine: S. Elad, Rochester; M. Imanguli, Dallas; J. Meier, ; N. S. Treister, Boston; W. Wagner, Mainz; T. Waltimo, Basel; J. W. Mays, Bethesda Physiotherapy: T. Daikeler, Basel; M. Kramer, Leipzig; S.-F. Meier, Pulmology: G. Hildebrandt, Salt Lake City; T. Lange, ; C. Schulz, 8 Limited number of participants. Registration mandatory. 107184_Falk WS_Prog_Inhalt.indd 8 14.02.13 10:03

List of Speakers, Moderators and Scientific Organizers PD Dr. Michael Albert Abteilung für Pädiatrische Hämatologie/Onkologie Dr. von Haunersches Kinderspital der LMU Lindwurmstr. 4 80337 München michael.albert@med.uni-muenchen.de Prof. Dr. Reinhard Andreesen Franz-Josef-Strauß-Allee 11 93053 reinhard.andreesen@ukr.de PD Dr. Francis Ayuk Interdisziplinäre Klinik für Stammzelltransplantation Universitätsklinikum Hamburg-Eppendorf Martinistr. 52 20246 Hamburg ayuketan@uke.de Prof. Dr. Hideo A. Baba Institut für Pathologie Universitätsklinikum Essen Hufelandstr. 55 45147 Essen hideo.baba@uk-essen.de Prof. Dr. Hartmut Bertz Innere Medizin I Universitätsklinikum Freiburg Hugstetter Str. 55 79106 Freiburg hartmut.bertz@uniklinik-freiburg.de PD Dr. Thomas Daikeler Rheumatologie Universitätsspital Basel Petersgraben 4 4031 Basel Switzerland thomas.daikeler@usb.ch Dr. Philipp Eberwein Universitäts-Augenklinik Freiburg Killianstr. 5 79106 Freiburg philipp.eberwein@uniklinik-freiburg.de Prof. Dr. Sharon Elad University of Rochester Medical Center Eastman Institute for Oral Health Division of Oral Medicine 625 Elmwood Ave. Rochester, NY 14620 USA selad@urmc.rochester.edu Prof. Dr. David Goldblum Augenklinik Universitätsspital Basel Petersgraben 4 4031 Basel Switzerland david.goldblum@usb.ch Prof. Dr. Hildegard Greinix Medizinische Universität Wien Klinik für Innere Medizin I Knochenmarkstransplantation Waehringer Gürtel 18-20 1090 Wien Austria hildegard.greinix@meduniwien.ac.at PD Dr. Peter Häusermann Dermatologie Universitätsspital Basel Petersgraben 4 4031 Basel Switzerland phaeusermann@uhbs.ch PD Dr. Sebastian Hahnel Poliklinik für zahnärztliche Prothetik 93042 sebastian.hahnel@ukr.de 9 107184_Falk WS_Prog_Inhalt.indd 9 14.02.13 10:03

Dr. Jörg Halter Innere Medizin Kantonsspital Basel Petersgraben 4 4031 Basel Switzerland jhalter@uhbs.ch Prof. Dr. Wolfgang Herr Innere Medizin III Universitätsmedizin der Johannes Gutenberg-Universität Langenbeckstr. 1 55131 Mainz w.herr@3-med.klinik.uni-mainz.de Gerhard Hildebrandt, M.D. Division of Hematology Hematologic Malignancies Huntsman Cancer Institute University of Utah 2000 Circle of Hope, RM 4261 Salt Lake City UT 84112-5550 USA gerhard.hildebrandt@hsc.utah.edu PD Dr. Uwe Hillen Dermatologie Universitätsklinikum Essen Hufelandstr. 55 45147 Essen uwe.hillen@uk-essen.de Prof. Dr. Ernst Holler Hämatologie/Onkologie 93042 ernst.holler@ukr.de Dr. Elisabeth Huber Institut für Pathologie 93042 elisabeth1.huber@ukr.de Matin Imanguli, DDS, M.D. University of Texas Southwestern Medical Center Department of Otolaryngology 323 Harry Hines Boulevard Dallas, TX 75390-9035 USA matin.imanguli@nih.gov Dr. Ulrike Just Dermatologie Medizinische Universität Wien Währinger Gürtel 18-20 1090 Wien Austria ulrike.just@meduniwien.ac.at Dr. Andreas Kreft Institut für Pathologie Universitätsmedizin der Johannes Gutenberg-Universität Langenbeckstr. 1 55131 Mainz andreas.kreft@unimedizin-mainz.de Dr. Florian Länger Institut für Pathologie MHH Hannover OE 5510 Carl-Neuberg-Str. 1 30625 Hannover laenger.florian@mh-hannover.de Dr. Tobias Lange Klinik für Innere Medizin II Franz-Josef-Strauß-Allee 11 93053 tobias.lange@ukr.de Dr. Anita Lawitschka SCT Outpatient Clinic St. Anna Kinderspital Kinderspitalgasse 6 1090 Wien Austria anita.lawitschka@stanna.at 10 107184_Falk WS_Prog_Inhalt.indd 10 14.02.13 10:03

Stephanie Lee, M.D. Professor of Medicine Fred Hutchinson Cancer Research Center 1100 Fairview Ave. N. P.O. Box 19024 Seattle, WA 89109 USA sjlee@fhcrc.org PD Dr. Thomas Longerich Institut für Pathologie Universitätsklinikum Heidelberg Im Neuenheimer Feld 224 69120 Heidelberg thomas.longerich@med.uni-heidelberg.de Dr. Christiane Marks Innere Medizin I Medizinische Universitätsklinik Hugstetter Str. 55 79106 Freiburg christiane.marks@uniklinik-freiburg.de Jacqueline W. Mays, DDS, Ph.D. NIDCR Clinical Research Fellow National Institute of Health Bldg 10, Rm 1N-118, MSC 1191 10 Center Drive Bethesda, MD 20892 USA maysjw@nidcr.nih.gov Dr. Dr. Johannes Meier Klinik und Poliklinik für MKG-Chirurgie 93042 johannes.meier@ukr.de Sebastian-Florian Meier Abteilung für Physiotherapie 93042 sebastian-florian.meier@ukr.de PD Dr. Ralf G. Meyer Hämatologie/Onkologie III. Medizinische Klinik u. Poliklinik Universitätsmedizin der Johannes Gutenberg-Universität Langenbeckstr. 1 55131 Mainz ralf.meyer@unimedizin-mainz.de Dr. Tobias Meyer-ter-Vehn Universitäts-Augenklinik Josef-Schneider-Str.11 97080 Würzburg meyer_t3@augenklinik.uni-wuerzburg.de Steven Z. Pavletic, M.D. Professor of Medicine National Cancer Institute Building 10 - Hatfield CRC Room 4-3130 10 Center Drive Bethesda, MD 20892 USA pavletis@mail.nih.gov Prof. Dr. Dr. Torsten E. Reichert Klinik und Poliklinik für MKG-Chirurgie 93042 torsten.reichert@ukr.de PD Dr. Christian Schulz Klinik für Innere Medizin II Franz-Josef-Strauß-Allee 11 93053 christian.schulz@ukr.de Prof. Dr. Esther von Stebut-Borschitz Dermatologie Universitätsmedizin der Johannes Gutenberg-Universität Langenbeckstr. 1 55131 Mainz vonstebu@uni-mainz.de 11 107184_Falk WS_Prog_Inhalt.indd 11 14.02.13 10:03

Nathaniel S. Treister, DMD, DMSc Brigham and Women s Hospital Division of Oral Medicine and Detistry 1620 Tremont Str., Suite BC-3-028 Boston, MA 02120 USA ntreister@partners.org Prof. Dr. Alexandar Tzankov Abteilung für Histopathologie und Autopsie Universitätsspital Basel Schönbeinstr. 40 4031 Basel Switzerland alexandar.tzankov@anti-clutterusb.ch Dr. Eva M. Wagner Innere Medizin Hämatologie/Onkologie III. Medizinische Klinik u. Poliklinik Universitätsmedizin der Johannes Gutenberg-Universität Langenbeckstr. 1 55131 Mainz eva.wagner@unimedizin-mainz.de Prof. Dr. Dr. Wilfried Wagner Klinik und Poliklinik für MKG-Chirurgie Augustusplatz 2 55131 Mainz wilfried.wagner@unimedizin-mainz.de Prof. Dr. odont. Tuomas Waltimo Klinik für Präventivzahnmedizin und Orale Mikrobiologie Departement Zahnmedizin Universität Basel Hebelstrasse 3 4056 Basel Switzerland tuomas.waltimo@usb.ch Jacqueline W. Mays, DDS, Ph.D. NIDCR Clinical Research Fellow National Institutes of Health Bldg 10, Rm 1N-118, MSC 1191 10 Center Drive Bethesda, MD 20892 USA maysjw@mail.nih.gov Prof. Dr. Daniel Wolff Hämatologie/Onkologie 93042 daniel.wolff@ukr.de Dr. Mirjana Ziemer Klinik für Dermatologie, Venerologie und Allergologie Philipp-Rosenthal-Str. 23 04103 Leipzig mirjana.ziemer@uniklinik-leipzig.de 12 107184_Falk WS_Prog_Inhalt.indd 12 14.02.13 10:03

General Information Prior to the opening of the Falk Workshop in Falk Foundation e.v. Telephone: +49 (0)761/1514-0 Congress Division Telefax: +49 (0)761/1514-359 Leinenwegerstr. 5 E-mail: symposia@falkfoundation.de 79041 Freiburg () General Information During the Falk Workshop University Hospital Telephone: +49 (0)175/7795327 Franz-Josef-Strauss-Allee 11 93053 Opening Hours: Friday, November 22, 2013 Saturday, November 23, 2013 7.00-19.00 h 8.00-16.30 h Congress Fees The participation at the Falk Workshops is free of charge. Please be aware that the number of participants is limited. Registration is mandatory. Refreshments during the coffee breaks and lunch on November 22-23 and dinner on November 22 and a copy of the abstract volume of the Falk Workshop are also free of charge. 13 107184_Falk WS_Prog_Inhalt.indd 13 14.02.13 10:03

Registration Congress registrations must reach the Falk Foundation e.v. by October 31, 2013 at the latest. After receipt of the registration form, each participant will be provided with confirmation of his registration. On presentation of this confirmation at the congress office in participants will receive the congress folder containing name badges, admission tickets and the abstract volume. All participants will receive a written confirmation of attendance and CME credits at the end of the meeting. Admission to Scientific Events For admission to scientific events your name badge should be clearly visible. Hotel Accommodation If you would like to do a hotel reservation, please contact: Tourist-Information Altes Rathaus Rathausplatz 4 93047 Telephone: +49 (0)941/507-4410 E-mail: tourismus@regensburg.de www.tourismus.regensburg.de/tourismus/home/3854 For further local information please contact: S. Blüml or G. Geissler Dept. of Hematology and Oncology University Hospital Telephone: +49 (0) 941-944-5542 or -5501 E-mail: susannna.blueml@ukr.de gertraud.geissler@ukr.de Airport International Franz-Josef-Strauß-Airport Munich Airport Nürnberg 14 107184_Falk WS_Prog_Inhalt.indd 14 14.02.13 10:03

Falk Workshop Workshop on oral cgvhd & on clinical practice in cgvhd November 22 23, 2013 University Hospital, Evening Activities 107184_Falk WS_Prog_AV.indd 1 21.01.13 15:53

Dinner at Leerer Beutel Bertoldstr. 9, 93047 Friday, November 22, 2013 20.00 Uhr Buffet and drinks. Free of charge, registration mandatory 107184_Falk WS_Prog_AV.indd 2 21.01.13 15:53

General Information: FALK FOUNDATION e.v. Leinenweberstr. 5 79108 Freiburg Telephone: +49(0)761/1514-0 Telefax: +49(0)761/1514-359 E-mail: symposia@falkfoundation.de www.falkfoundation.org Falk Workshop Workshop on Oral cgvhd & Clinical Practice in cgvhd Falk Foundation e. V. Congress Division Leinenweberstr. 5 79108 Freiburg November 22 23, 2013 University Hospital, Please print or legibly stamp your name and professional address! General Information: FALK FOUNDATION e.v. Leinenweberstr. 5 79108 Freiburg Congress Division Telephone: +49(0)761/1514-0 Telefax: +49(0)761/1514-359 E-mail: symposia@falkfoundation.de www.falkfoundation.de P WS 1-9/2012/3.000 Stü Program Application for CME credits submitted 107184_Falk WS_Prog_UG.indd 1 12.02.13 13:00

Directions to University Hospital REGISTRATION CARD Falk Workshop November 22 23, 2013 (), Franz-Josef-Strauß-Allee 11, 93053 Main Entrance Dinner at Leerer Beutel Friday, November 22, 2013, 20.00 h (for details see enclosed Evening Activities ) I will attend the Falk Workshop on clinical cgvhd on November 23, 2013 (limited number of participants) Meeting of pathology groups on November 22, 2013 (Institut of Pathology, 12.00-15.00 h) I will attend the Falk Workshop on Oral cgvhd on November 22, 2013 November 22 23, 2013 () Falk Workshop Clinical practice in cgvhd Workshop on Oral cgvhd & Registration Deadline: October 31, 2013 107184_Falk WS_Prog_UG.indd 2 12.02.13 13:00