1 ANS 431 - Reproductive Physiology of Domestic Animals (Spring 2016) Instructor: Dr. Eduardo L. Gastal, DVM, MS, PhD Room: AG 129; Phone: 453-1774; E-mail: egastal@siu.edu Office hours: MWF 11-12 a.m.; MF 4-6 p.m. or by appointment. Teaching Assistants (TAs): Our apologies but we will have No TA this semester Time: Lecture: 10:00 to 10:50 a.m., MWF at room AG 153 Labs: 8:00 to 9:50 a.m. (Section 1), 10:00 to 11:50 a.m. (Section 2) Thursday at AG 114. Attendance is mandatory in laboratories. Lab coats for labs in AG 114, and adequate barn clothes for labs at the farms are mandatory. Course Learning Objectives: The objective of this course is to allow the students to know and understand the following: general anatomy and histology of the male and female reproductive systems; endocrinology of the estrous cycle, pregnancy, and lactation; estrous cycle and gestation in farm animals; functions of the cells of the ovary and testis; basics of oocyte and spermatozoa maturation; transport of gametes through the male and female reproductive systems; steps involved in fertilization; basic events of embryo and fetal development; basics of maternal recognition of pregnancy, implantation, and placentation; events of parturition; events of courtship and mating in farm animals; general causes and examples of reproductive failure in farm animals; reproductive peculiarities and management of cattle, sheep, horses, swine, and poultry; basics of reproductive-assisted biotechnologies including AI, estrus synchronization, superovulation, embryo transfer, IVF, sperm and embryo sexing, transgenics, and reproductive immunization. Student Groups: This course will have 10 groups of 2 students in each one. Different group tasks will be performed including study guide answers-review session, and video-clip questions and discussion.
2 Study Guide - Review Session: Every lecture handout will have several questions to serve as a study guide for the students to prepare for the quizzes (in class and lab) and exams. Students are encouraged to study the answers of the questions posted online. Every Friday, a short review (first 15 minutes) of the week s lectures will be performed. After the short review, one or two short videos covering the previous material will be shown. Hours of Study Required for this Course: At least 4 hours per week. Textbook: Senger P.L. 2003, 2005, 2012. Pathways to Pregnancy and Parturition. 2 nd or 3rd revised edition. Current Conceptions, Inc. Other References: Hafez B., Hafez E.S.E. 2000. Reproduction in Farm Animals. 7th edition. Lippincott Williams & Wilkins. Knobil E., Neill J.D. 1994. The Physiology of Reproduction. 2nd edition. Raven Press. Knobil E., Neill J.D. 1998. Encyclopedia of Reproduction. Academic Press. Vols. 1-4. Ginther O.J. 1992. Reproductive Biology of the Mare, Basic and Applied Aspects, 2nd edition. Cross Plains, WI: Equiservices Publishing. Ginther O.J. 1995. Ultrasonic Imaging and Animal Reproduction: Book 2, Horses. Cross Plains, WI: Equiservices Publishing. Ginther O.J. 1998. Ultrasonic Imaging and Animal Reproduction: Book 3, Cattle. Cross Plains, WI: Equiservices Publishing. Grading: Questions regarding the Video-clips/discussion will be considered as a quiz. Additional pop-up quizzes should be expected in this course, mainly on Fridays. Exams: Exams will be given during the lecture period in room AG 153. Students may come early and remain later than the scheduled lecture period. Contact instructor for specifics. Exam formats may vary throughout the semester, but students should expect to see multiple choice, true/false, short answer and essay questions
3 (this can also be expected of the quizzes). Students should review their missed questions and return exam on the following class. Students will miss points if exams are NOT returned on time! Three mid-terms (Exam 1, Exam 2, Exam 3) and a Final Exam will be given in the course. Students will be waived from the Final Exam in case at least a grade B of a cumulative score was obtained until the Exam 3. Make-up exams will be essay or oral at the instructors' discretion. 20% will be taken off the top of any make-ups given to students who do not notify an instructor before the regularly scheduled exam. The Final may be 50% comprehensive. The final will only be given at the scheduled time - no make-ups or early exams. Students that do not take the final will be given "0" on the final or an incomplete depending on the circumstances determined by the instructor. Attendance: Attendance is important and will be considered mandatory in both lab and lecture periods and will be factored into the student s grade, accounting for 10%. Grading Breakdown: 10% Attendance A=90 to 100% 10% Participation B=80 to 89% 10% Quizzes 50% 3 Exams C=70 to 79% 20% Final Exam D=60 to 69% 100% Total F=<60% Changes to these grade items and points allocated are at the discretion of the instructor. If grades are applied to a curve the instructor reserve the right to lower the curve as appropriate. The curve will not be raised. Graduate students will not be included in the undergraduate student curve. Academic Honesty: The academic honesty policy will follow the Student Conduct Code. ADA Accommodation: In keeping the goal of the implementation of the Americans with Disabilities Act (ADA), all students for whom the act applies should notify the instructor no later than the second session of the course so that arrangements can be made for accommodations to meet your educational needs and maximize learning.
4 Tentative Schedule Spring 2016 Week Date Title Reading in Text 1 Jan 20 Lec 1a First day of class Survey about Course and Content Assessment Jan 21 Lab 1 Class knowledge assessment (Quiz) and discussion. Generalities about the course and introduction to each other Jan 22 Lec 2a Female reproductive tract anatomy Chapter 1, 2 2 Jan 25 NO CLASS. Every group should find 3 videos on internet for us to look in class. Jan 27 Jan 28 Jan 29 Lec 2b cont. Female reproductive tract anatomy Lab 2 Female anatomy and AI practice with the genital tracts 3 Feb 1 Lec 3a Female comparative anatomy Feb 3 Feb 4 Feb 5 Lec 3b cont. Comparative female anatomy, historical perspectives Lab 3 Female anatomy, AI practice, follicular aspiration from tracts, GC, oocytes (Lab quiz) 4 Feb 8 Lec 4 Male reproductive tract anatomy Chapter 3 of the male and female Feb 10 Lec 5 Comparative male reproductive tract Chapter 3 Feb 11 Feb 12 Lab 4 Male reproductive tract anatomy 5 Feb 15 Lec 6a Embryogenesis, sexual/genital development Chapter 4 Feb 17 EXAM 1 Feb 18 Lab 5 Dissection of the male genital tract of the bull; boar; and epididymis sperm collection (Lab quiz) Feb 19 6 Feb 22 Lec 6b Embryogenesis, sexual/genital development Chapter 4 of the male and female
5 Feb 24 Lec 6c Sexual differentiation Chapter 4 Feb 25 Feb 26 Lab 6 Videos watch and discussion 7 Feb 29 Lec 7a Endocrinology of reproduction Chapter 5 Mar 2 Lec 7b Endocrinology of reproduction Chapter 5 Mar 3 Mar 4 Lab 7 Gynecologic exam and AI cows 8 Mar 7 Lec 7c Endocrinology of reproduction-mechanism of hormone action Chapter 5 Mar 9 EXAM 2 Mar 10 Lab 8 Male exam, testis size, and semen collection bull Mar 11 Lec 8a Puberty Chapter 6 9 Mar 12-20 SPRING BREAK 10 Mar 21 Lec 8b Puberty Mar 23 Lec 9a Reproductive cycles in the female Chapter 7 Mar 24 Mar 25 Lab 9 Gynecologic exam and AI mares 11 Mar 28 Lec 9b cont. Reproductive cycles in the female Chapter 7 Mar 30 Lec 10a Follicular phase of the estrous cycle, follicular waves, Chapter 8 oogenesis, ovulation Mar 31 April 1 Lab 10 Male exam, testis size, and semen collection stallion 12 April 4 Lec 10b Follicular phase of the estrous cycle, follicular waves, Chapter 8 oogenesis, ovulation April 6 Lec 11a Luteal phase of the estrous cycle, the menstrual cycle, and Chapter 9 estrus synchronization April 7 April 8 Lab 11 Pregnancy check in cows (rectal palpation + ultrasonography) 13 April 11 Lec 11b Luteal phase of the estrous cycle, the menstrual cycle, and Chapter 9 estrus synchronization
6 April 13 Lec 12 Sexual Behavior and applied reproductive behavior of the male Chapter 11 April 14 April 15 Lab 12 AI and estrus detection sows 14 April 18 Lec 13 Semen collection and processing, and artificial insemination April 20 EXAM 3 April 21 Lab 13 Ultrasonographic examination + embryo transfer (mare) April 22 Lec 14a,b Spermatogenesis Chapter 10 15 April 25 Lec 14c Sperm, epididymis, ejaculation, semen Chapter 10 April 27 Lec 15 Gamete transport Chapter 12 April 28 April 29 Lab 14 Ovum pick-up or Embryo flushing in cow 16 May 2 Lec 16 Fertilization, embryo development Chapter 12,13 May 4 Lec 17 Placentation and maternal recognition of pregnancy Chapter 13, 14 May 5 Lec 18 Pregnancy loss and parturition Chapter 14,15 May 6 May.. (.).. a.m/p.m. FINAL EXAM ----------------------------------------