WELCOME. to the DePuy Synthes Institute, LLC

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2 WELCOME to the DePuy Synthes Institute, LLC Healthcare professionals from around the world come to the DePuy Synthes Institute to learn, connect and share knowledge with the common goal of improving patient care. The Institute embodies the DePuy Synthes Companies of Johnson & Johnson tradition of innovative approaches to healthcare and our continued commitment to advancing professional education and research for orthopaedic, spinal, and neurosurgical care.

3 JOIN US. INSPIRED SOLUTIONS DePuy Synthes Companies of Johnson & Johnson are Orthopaedic and Neurological solutions companies inspired by the people we serve. We offer an unparalleled breadth and depth of products, services and programs in the areas of joint reconstruction, trauma, spine, sports medicine, neurological, craniomaxillofacial, power tools and biomaterials. By listening to you, our patients, physicians, providers, payers and partners, we are able to activate insights and translate our knowledge to provide life changing solutions. Together, we create inspired solutions that advance patient care.

4 The DePuy Synthes Institute offers specialized programs to healthcare professionals interacting with patients throughout the continuum of ADVANCING EDUCATION care for every stage of learning. Innovative, technology-driven solutions are quintessential to providing healthcare professionals with the most effective education. Anytime, anywhere education provides access to quality learning opportunities from various destinations via a range of modalities.

5 Explore the opportunities. To accommodate distance learners, a variety of online resources are available via DePuySynthesInstitute.com. Here you will find education modules designed specifically for residents, fellows, physicians and nurses. Course A course can be a mix of presentations, case reviews, instrumentation, treatment therapies, surgical techniques and endovascular techniques with the addition of a hands on lab. Courses are typically led by three to ten HCP Consultants with experience to meet your education needs. HCPs are able to share knowledge with peers and faculty. Courses may be located at one of our locations or at another training facility. Symposium A panel of experts who discuss their experiences on a particular topic before a group of HCPs, to include: faculty, fellows and residents. The symposium is meant to be interactive with the panel answering attendees questions on solving tomorrow s challenges today. Platform for Education And Knowledge (PEAK) PEAK Events allow the HCPs to engage in lively discussion and debate with other HCP experts through an informal setting close to home. The HCP faculty provides lectures and/or case reviews on current clinical issues relating to the effective use of DePuy Synthes Companies of Johnson & Johnson products. Faculty could be present at the dinner or participating via real-time video conferencing. Worldwide Customer Visit (WWCV) A HCP or surgical team from the same institution visits a DePuy Synthes Companies of Johnson & Johnson site for a day. There is a customized agenda to meet the visitor s needs. The agenda typically includes product discussion and an introduction to DePuy Synthes Companies of Johnson & Johnson employees. This may also have a lab component if requested. Peer-to-Peer These programs are designed to provide an opportunity for experienced HCPs to discuss current trends with their colleagues. Participants contribute through case based presentations assigned by the course chairs; the objective is to enhance the HCPs knowledge and skills in treatment options for their patients. This interactive program is designed for a small number of participants. Tutorial A tutorial accommodates a small group of faculty and participants. The program typically includes observation of live surgery, didactic sessions and a group dinner. A second half day session may include hands-on anatomic training or a bioskills opportunity and case discussion. Small, Market Appropriate, interactive, Training (SMART) Lab These technique intensive programs are focused on the practicing HCP. SMART Labs may be particularly effective for experienced surgeons using a competitive system who have an interest in changing their operative protocol to DePuy Synthes Companies of Johnson & Johnson products or for experienced health care workers who provide the day-to-day patient care. OR Visitation Designed to provide the opportunity to meet experienced surgeons in either a one-on-one setting or in a small group. Participants observe live surgery and discuss surgical technique, indications and clinical results. This may also have a lab if requested and available. All programs may not be available for all divisions.

6 Flexible learning environments. Cutting-edge audio visual production equipment is available with on-site technical assistance. Classrooms can be setup in standard schoolroom style, u-shape, conference or pod settings to accommodate a variety of meeting formats. We offer video conferencing and presentation capabilities for multiple locations and connection types. Video conferencing can reduce time, cost and travel commitment while improving engagement between healthcare professionals and external persons. The Institute s auditorium provides you with the flexibility for presenting to large audiences. Breakout areas offer additional space for guests to gather outside of the classroom or laboratory. Seating areas are arranged throughout the facility, allowing for guests to connect and share in a less formal environment. State-of-the-art dry and wet labs can accommodate up to 19 stations. These laboratories provide hands-on learning experience to Orthopaedic and Neuroscience customers on the safe and effective use of DePuy Synthes Companies of Johnson & Johnson products. Delicious dining options are available through the Bistro at our Raynham, MA location. Quality catering services are provided at our other facilities.

7 You are invited to explore the versatility of the We welcome you to Learn, Connect, & Share at the DePuy Synthes Institute. EDUCATION DESTINATION DePuy Synthes Institute, and advance your expertise in one of our three state-of-the art training facilities around the globe. With locations in Raynham, Massachusetts, Palm Beach Gardens, Florida, and West Chester, Pennsylvania you will find an array of learning environments aimed at providing a world-class educational experience. Whether it s in a classroom, a sub-dividable auditorium with seating for 200, one of our multiple laboratory spaces for hands-on-training, or remotely Raynham, MA 325 Paramount Drive Raynham, MA Palm Beach Gardens, FL 4600 Riverside Drive Palm Beach Gardens, FL West Chester, PA 1302 Wrights Lane East West Chester, PA Together, we will advance education to improve patient care. through our cutting edge communication equipment, we welcome you to the DePuy Synthes Institute. DePuy Synthes Institute, LLC 325 Paramount Drive Raynham, MA T. +1 (508) DePuy Synthes Institute, LLC All rights reserved. DSUS/INS/1214/ /15 Massachusetts and Vermont HCP Requirements Under Massachusetts regulations, DePuy Synthes Companies may provide meals or refreshments to Massachusetts licensed HCPs only during non- CME educational activities when educating and informing HCPs about the benefits, risks, and appropriate uses of our medical devices, disease states, or other scientific/health economics information. Under Vermont regulations, DePuy Synthes Companies may provide meals or refreshments in conjunction with technical product training on the use of medical devices to Vermont-licensed HCPs that regularly practice in the state of Vermont. Government HCPs Per company policy, meals and refreshments may not be provided to Federal Government HCPs unless pre-approved by DePuy Synthes Companies. Meals and refreshments provided to State and Local Government HCPs are permitted upon verification of allowance by facility policy. Disclosure DePuy Synthes Companies may be required by Federal, state, local laws, or requirements of government agencies, to disclose certain value transfers made to hospitals, physicians, and other practitioners, including but not limited to, nurse practitioners and physician assistants. This information may become publicly available as required by law. The company may also choose to publicly post such information on its website. Additional Information In accordance with the AdvaMed Code of Ethics on Interactions with Health Care Professionals, and DePuy Synthes Companies policy, spouses or guests may not attend Company-sponsored events. This course is produced and sponsored by DePuy Synthes Companies and is not approved for CME credit.