Crystal Structure Determination of 5,6-Dibromoacenaphthene from X-ray Powder Diffraction Data



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ScienceAsia 28 (2002) : 271-275 Crystal Structure Determination of 5,6-Dibromoacenaphthene from X-ray Powder Diffraction Data Nongnuj Jaiboon* Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. * Corresponding author, E-mail: nongnuj.j@chula.ac.th Received 14 Feb 2001 Accepted 8 Jan 2002 ABSTRACT The new crystal structure of 5,6-dibromoacenaphthene has been successfully determined from X-ray powder diffraction data with monoclinic crystals, P2 1 /n, a = 7.88(1) Å, b = 11.64(1) Å, c = 11.62(1) Å, β =107.09(9), V = 1019.9(1) Å 3 and Z = 4. Individual reflection intensities were extracted by means of Le Bail s method. The molecular structure of 1 was solved by direct methods and refined using the combination of least-squares and Rietveld methods. The final Rietveld refinement converged to the value of R p = 0.114, R wp = 0.155, Bragg-R f = 5.28 for 8532 data points and 933 extracted reflections collected in the 2 < 2θ < 95 range. The molecules have an interplanar π-π interaction between the acenaphthene planes with the average distance of 3.57(9) Å. Moreover, the molecular dimer-pairwise packing diagram has an unexpected straight stacking, as opposed to the usual lateral stacking normally occured in 5,6-dihaloacenaphthene. KEYWORDS: Structure determination, X-ray powder diffraction, Rietveld Method, 5,6-dibromoacenaphthalene. INTRODUCTION X-ray single-crystal diffraction (XRSC) is the most powerful technique for determining crystal structures. Until recently, crystal structure determination from X-ray powder diffraction (XRPD) data was a challenging task. 1 Crystal structures of organic compounds determined from X-ray powder diffraction data are rare. 2 This paper reports a new crystal structure of 5,6-dibromoacenaphthene, which was determined from XRPD data using an ab initio method. The ab initio structure determination is the procedure of solving the phase problems without a preliminary model. This method is usually applied to classic inorganic compounds. 3 In this technique, the powder diffraction data must be extracted into three-dimensional data in the same reciprocal lattice as the data collected from the XRSC technique using the full-pattern decomposed methods. After the data were extracted successfully, the phase problem was solved using the direct methods or the Patterson method. Finally, the model structure was refined using the least-squares and the full-pattern fitting methods (Rietveld method). In this paper the crystal structure of the title compound was determined from X-ray powder diffraction data. Its topology, crystal packing and intermolecular interactions, namely a π-π interaction, of the title compound were studied and were compared with the related compounds searched in the Cambridge Structural Database (CSD). 4 In addition, the molecular dimer-pairwise packing diagram of the title compound has an unexpected straight stacking, as opposed to the usual lateral stacking diagrams, which normally occurred in 5,6- dihaloacenaphthene. MATERIALS AND METHODS X-ray data collection The sample was gently ground in an agate mortar. The resulting powder was side loaded into a sample holder, and was smoothed with a glass slide to reduce preferred orientation. The step-scanned diffraction data were measured on a Rigaku diffractometer using graphite monochromatized Cu-K α radiation (λ=1.5406 Å) operating at 40kV and 30mA. The divergence slit size was 1 mm and the receiving slit was 0.1 mm. The pattern was collected in the 2 < 2θ < 100 range with a step size of 0.01 and counting time of 10 seconds per step. The K α2 contribution was mathematically removed from the data. The

272 ScienceAsia 28 (2002) pattern was indexed using TREOR90 programs 5 on the basis set of the highest 20 observed lines. The best solution which indexed all the lines indicated a monoclinic unit cell with parameters a =7.88(1) Å, b=11.64(1) Å, c = 11.62(1) Å, b = 107.09(9), V = 1019.9(1) Å 3. The systematic absences were consistent with the space group P2 1 /n (h0l; h+l = 2n, h00; h = 2n, 0k0; k = 2n, 00l; l = 2n). Structure solution and refinement Initially, the powder pattern was refined by FULLPROF program 6 using the following parameters; zero point error, background parameters (polynomial functions), peak shape profiles (Pseudovoigt coefficient) 7, FWHM parameters and lattice parameters. In this stage no structural model was used in the refinement cycles. Individual reflection intensities were extracted by means of Le Bail s decompositions 8 of which 933 individual reflections were extracted. This extracted data was then used to solve the structure by direct methods using SHELXS-97 for PC 9. The two bromine atomic positions were found from electron density maps; Br1 (0.1190, 0.9073, 0.3554), Br2 (0.4086, 0.9276, 0.2073), and were used as a starting structural model in the Rietveld refinement using FULLPROF. The individual intensities were re-extracted and a direct methods calculation was then recomputed until all non-hydrogen atoms were found. The model structure was refined using least squares method and difference Fourier maps. At the last step, all nonhydrogen atoms were found from difference Fourier maps, except for C6 and C12 which had to be calculated from idealized rigid planar positions using SHELXL-97 12. All non-hydrogen atoms, except Br1 and Br2, were refined with isotropic displacement parameters and Br1 and Br2 were refined with anisotropic displacement parameters. The atomic positions of C1, C6 and C11 were disordered and refined with fixed isotropic displacement parameters. All hydrogen atoms were placed in calculated positions and were refined with a riding model 9 with Uiso being 1.5U eq of the C-atoms to which they were attached. The final Rietveld refinement gave Rp = 0.114 and Rwp = 0.155. The final Rietveld plot is shown in Fig 1. Crystallographic data and details of the Rietveld refinement are given in Table 1. 8200 Intensity (a.u.) 7200 6200 5200 Yobs Ycalc Yobs-Ycalc Bragg_position 4200 3200 2200 1200 200-800 -1800-2800 8 13 18 23 28 33 38 43 48 53 2 Theta (deg.) Fig 1. Experimental (o), calculated (solid line) and difference powder X-ray diffraction profiles for the Rietveld refinement of 5,6- dibromoacenaphthalene. Reflection positions are marked. The calculated powder diffraction profile is for the final refined crystal structure.

ScienceAsia 28 (2002) 273 RESULTS AND DISCUSSION The crystal structure of 5,6-dibromoacenaphthalene (1) was successfully determined from X-ray powder diffraction data. The drawing of this compound with atomic labeling is shown in Fig 2. Atomic positions for all non-hydrogen atoms, relevant bond distances and bond angles are given in Table 2 and Table 3, respectively. It should be noted that the structure determination of 1 from X- ray powder diffraction data was able to give only Table 1. Crystallographic Data for 5,6-dibromoacenaphthalene (C 12 H 8 Br 2 ). Formula weight 312.02 Crystal system Monoclinic Space group P2 1 /n (No.14) a 7.88(1) Å b 11.64(1) Å c 11.62(1) Å β 107.09(1) V 1019.9(1) Å 3 Z 4 D cal 2.023 g cm -3 λ (Cu Kα 1, Kα 2 ) 1.54056, 1.54433 Å Temperature (K) 298 Data range ( ) 2 2θ 95 No. profile point 8532 No. parameters 111 Peak shape function Pseudo-voigt Background Polynomial function R exp 0.066 R p 0.114 R wp 0.155 C12 C11 C1 C2 C9 C3 C8 C7 C6 C10 Fig 2. An ORTEP 12 view of 5,6-dibromo acenaphthalene. C4 C5 Br1 Br2 average bond distances, overall topology, molecular conformations and crystal packing diagram. Table 2. Atomic coordinates (x10 4 ) and equivalent isotropic displacement parameters ( Å 2 x 10 3 ). Atom x y z U(eq) Br(1) 1091(5) 945(3) 3492(3) 67(2) Br(2) 4169(6) 733(4) 2100(4) 94(2) C(1) -1570(40) -2140(20) 920(30) 22(9) C(2) 490(40) -2220(30) -120(30) 45(11) C(3) 1810(40) -1840(30) -400(20) 40 C(4) 2890(30) -1040(20) 310(30) 23(10) C(5) 2570(40) -430(20) 1250(20) 16(10) C(6) 220(40) -320(20) 2440(30) 40 C(7) -1280(40) -800(20) 2550(20) 21(10) C(8) -2190(40) -1680(30) 1840(30) 38(11) C(9) 0(40) -1710(30) 800(30) 31(10) C(10) 940(40) -790(20) 1520(20) 12(9) C(11) -2170(40) -3160(20) 50(20) 40 C(12) -830(30) -3220(20) -650(20) 21(9) CT01 367-1308 1098 10 U(eq) is defined as one third of the trace of the orthogonalized Uij tensor. Table 3. Bond lengths [Å] and angles [ ] for 5,6- dibromoacenaphthalene. Br(1)-C(6) 1.91(3) C(3)-C(4) 1.36(3) Br(2)-C(5) 1.92(2) C(4)-C(5) 1.39(3) C(1)-C(9) 1.38(4) C(5)-C(10) 1.47(3) C(1)-C(8) 1.40(3) C(6)-C(7) 1.35(3) C(1)-C(11) 1.55(3) C(6)-C(10) 1.46(3) C(2)-C(3) 1.26(4) C(7)-C(8) 1.37(3) C(2)-C(9) 1.37(3) C(9)-C(10) 1.43(3) C(2)-C(12) 1.57(3) C(11)-C(12) 1.52(3) CT01 - CT01 i 3.91(2) C(9)-C(1)-C(8) 118(3) C(7)-C(6)-Br(1) 115(3) C(9)-C(1)-C(11) 108(3) C(10)-C(6)-Br(1) 128(2) C(8)-C(1)-C(11) 133(3) C(6)-C(7)-C(8) 125(3) C(3)-C(2)-C(9) 120(3) C(7)-C(8)-C(1) 120(3) C(3)-C(2)-C(12) 132(4) C(2)-C(9)-C(1) 113(3) C(9)-C(2)-C(12) 109(3) C(2)-C(9)-C(10) 125(3) C(2)-C(3)-C(4) 120(3) C(1)-C(9)-C(10) 122(3) C(3)-C(4)-C(5) 127(3) C(9)-C(10)-C(6) 118(3) C(4)-C(5)-C(10) 113(3) C(9)-C(10)-C(5) 115(3) C(4)-C(5)-Br(2) 122(2) C(6)-C(10)-C(5) 127(3) C(10)-C(5)-Br(2) 125(2) C(12)-C(11)-C(1) 105(2) C(7)-C(6)-C(10) 117(3) C(11)-C(12)-C(2) 104(2) C(4)-C(11)-C(12)-C(5) 1(3) Symmetry transformations used to generate equivalent atoms: i : -x, -y, -z.

274 ScienceAsia 28 (2002) Fig 3. Molecular packing of 5,6-dibromoacenaphthalene along the a-axis, showing the π-π interaction between the acenaphthalene plans with the distance of 3.57(9) Å. Comparison with 1,8-dibromonaphthene, in 1 the ethylene bridging the 1,2-positions has forced the 5,6-dibromoacenaphthene framework planar. Deviation of the acenaphthene carbon atoms from their least-squares planes (C1 to C10) are in the range of 0.07(2) Å to 0.03(2) Å. The C-C bond distances in the acenaphthene ring showed considerable variation, falling in the range of 1.34(3) Å to 1.47(3) Å. These are corresponding to a search from the Cambridge Structural Database that the frameworks of dihaloacenaphthene were planar and the frameworks of dihalonaphthene were not planar. The bond distances of Br1-C1 (1.91(3) Å) and Br2-C2 (1.92(2) Å) were within the expected theoretical Br-C distance of 1.94 Å, but they were longer than that of 1.893 Å in 5-bromo, 6-chloroacenaphthene. 10 The bridging ethano carbon atoms (C11 and C12) also lay in the naphthalene plane with the C11 and C12 deviations of 0.12(3) Å and 0.12(3) Å, respectively, and C4-C11-C12-C5 torsion angle of 1(3). Using the lastest version 5.12 of Cambridge Structural Database (CSD) 4, a survey of crystal structures of 5,6-dihaloacenaphthene revealed that Fig 4. A p-p stacked pair of 5,6-dibromoacenaphthene.

ScienceAsia 28 (2002) 275 the molecules prefer to stack laterally in a dimerpairwise mode. This is probably due to the minimization of the repulsive force between the halogen atoms and between the ethylene bridges. When comparing between 1 and 5,6-dichloroacenaphthene 12, it can be seen that even though 1 is overcrowded with the bromine atoms, the acenaphthalene frameworks are packed in an unexpected straight dimer-pairwise of a herringbone type (Fig 3). The acenaphthalene planes are found in centrosymmetrically related pairs and parallel to one another by π-π interactions (Fig 4) with the interplanar distance of 3.57(9) Å, and the distance between their centroids [CT01...CT01(-x, -y, -z) = 3.91(2) Å]. ACKNOWLEDGEMENT I am grateful to Dr M Watkinson and Dr RG Prichard for providing the 5,6-dibromoacenaphthalene. The financial support for this research was provided by the National Science and Technology Development Agency (NSTDA) to Nongnuj Jaiboon (CO-B-06-33-09-201). I wish to thank Dr Veera Muangsin and Dr Thawatchai Tuntulani for kind suggestions and reading of the manuscript. REFERENCES 1. Harris KDM and Tremayne M (1996) Crystal structure determination from powder diffraction data. Chem Mater 8, 2554-70. 2. Wessels T, Baerlocher C and McCusker LB (2000) Singlecrystal-like diffraction data from polycrystalline meterials. Science 284, 5413, 477-9. 3. Reviews in Mineralogy (1989), The Mineralogical Society of America, Wahington DC, Vol 20. 4. The Cambridge Structural Database (CSD) (2000), Cambridge Crystallographic Data Centre, Cambridge, UK. 5. Werner PE, Erikson L and Westdahl M (1985) TREOR, a semiexhaustive trial-and-error powder indexing program for all symmetries. J Appl Cryst 48, 367. 6. Rodriguez-Carvaj J, FULLPROF program, In: Collected Abstracts of Powder Diffraction Meeting: Toulouse, France, July, 1990, 127. 7. Thompson P, Cox DE, Hastings JB, (1987). Rietveld refinement of Debye-Scherrer synchrotron X-ray data from Al 2 O 3. J Appl Cryst 20, 79. 8. Le Bail A, Duroy H, Forquet JL (1988) Ab initio structure determination of LiSbWO 6 by X-ray powder diffraction. Mater Res Bull 23, 447. 9. Sheldrick GM (1997) SHELX-97, University of Gottingen, Germany. 10.Avoyan RL, Struchkov YT (1961) Zh Strukt Khim 5, 407, 1964. 11.Avoyan RL, Struchkov YT (1961) Zh Strukt Khim 2, 719. 12.Johnson CK and Bernett MN (1996) ORTEP-3 for Windows, University of Glasgow, UK.