Translational and Clinical Research Course for Clinician-Scientists

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American Neurological Association s 7 TH ANNUAL Translational and Clinical Research Course for Clinician-Scientists July 19 21, 2015 Mt. Washington Conference Center, Baltimore, MD myana.org/programs/translational-and-clinical-research-course 1

7 TH ANNUAL Translational and Clinical Research Course for Clinician-Scientists July 19 21, 2015 Mt. Washington Conference Center, Baltimore, MD Course Description The course is designed to further the development of young neuroscientists interested in or engaged in translational or clinical research. Compared to fields like oncology, cardiology, and diabetes and metabolism, the clinical neurosciences currently lack well-established pathways for providing this kind of training for fellows and junior faculty. This three-day course will engage selected research fellows, residents, and junior faculty in an analysis of the development of therapies for neurological diseases. The purpose of this course is to encourage trainees and junior faculty to pursue careers in neurology, in particular academic neurology. Throughout the course, strategies for career development will be interwoven with the didactic material. The sequence of topics will work forward from the early stages of development, including initial screening and efficacy testing in model systems, to the evolution of therapeutic hypotheses, through early-, middle-, and late-stage clinical trials, and the post-marketing assessment of therapies testing. Lectures, group discussions, and case examples will be used as learning strategies. Each day will include time for networking with other participants and speakers. Small group discussions will allow participants to further explore specific areas of interest. 2015 Translational and Clinical Research Course Committee Craig Blackstone, M.D., Ph.D., Chair, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, MD Jacqueline French, M.D. New York University, New York, NY Karl Kieburtz, M.D., M.P.H. University of Rochester, Rochester, NY Christopher Austin, M.D. National Institutes of Health (NIH), Bethesda, MD Barbara Slusher, Ph.D., M.A.S. John Hopkins University School of Medicine, Baltimore, MD Jeremy Shefner, M.D., Ph.D. Barrow Neurological Institute, Phoenix, AZ Justin C. McArthur, M.B.B.S., M.P.H., F.A.A.N. Johns Hopkins University School of Medicine, Baltimore, MD 2

Accreditation and Designation Statement(s) The American Neurological Association (ANA) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians. ANA designates this live activity for a maximum of 12.5 AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity. For detailed CME information, please reference the CME Information & Instructions Program Insert on-site at the Translational and Clinical Research Course for Clinician-Scientists. Application Process To register, please complete the following registration form and return by email to szuba@myana.org. Or use the online form found at myana.org/7th-annual-tcrc-application-form. A complete packet will include the following: 1. A complete application form. 2. A statement including: A short introduction of yourself and an outline of your current position, career plan, and clinical/translational research interests. Your career goals for the next 10 years. Your primary objectives for this course (what you hope to learn/accomplish). 3. A copy of your bio-sketch or CV with abbreviated bibliography. Deadline The application, statement, and bio-sketch should be submitted electronically by using the online form or email to szuba@myana.org no later than May 31, 2015. Please note: If your packet does not include a personal statement and/or bio-sketch, the application will be incomplete and will not be considered. Course Fees There is no registration fee for the course. ANA will also cover a two-night hotel stay on July 19 and 20 at the Mt. Washington Conference Center, Baltimore, MD. As a participant, you are responsible for covering costs associated with all other travel arrangements and fees. Selection Process Participants complete applications will be subject to committee review to confirm that the applicant s career path and background are appropriate for the course. Acceptance to the course is based on potential for a research career and the value of the course to the applicant given their career stage. Applicants will be notified of their status in June 2015. { } SPACE IS LIMITED. APPLICATION DEADLINE IS MAY 31, 2015 Testimonials Excellent! Built in time to develop and reinforce professional relationships. This was a nice chance to discuss more informally with mentors in a more personal style and get some useful information/advice all of them were accessible and willing to share insight. 3

Schedule: SUNDAY, JULY 19 4:30 p.m. 6:00 p.m. Registration 6:00 p.m. Evening Arrival, Welcome Reception, and Dinner MONDAY, JULY 20 7:00 a.m. 8:00 a.m. Breakfast 8:00 a.m. 8:30 a.m. Introduction Course Director, Craig Blackstone, M.D., Ph.D., National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH) 8:30 a.m. 9:15 a.m. Producing Neurological Therapies: How We Are Doing Walter Koroshetz, M.D., National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH) 9:15 a.m. 10:00 a.m. How Clinical Development Can Inform Translational Science Jacqueline French, M.D., New York University Langone Medical Center 10:00 a.m. 10:15 a.m. Break 10:15 a.m. 11:00 a.m. Using the Clinical and Translational Science Award System Effectively Karl Kieburtz, M.D., M.P.H., University of Rochester Medical Center 11:00 a.m. 11:45 a.m. Innovative Roles of NCATS in Translational Neurology Petra Kaufmann, M.D., M.S., National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH) 12:00 p.m. 1:30 p.m. Lunch 1:30 p.m. 2:15 p.m. Keynote Address Merit Cudkowicz, M.D., Massachusetts General Hospital/Harvard Medical School 2:15 p.m. 3:00 p.m. Designing Early Stage Trials: Examples from Muscular Dystrophy Research Kathryn Wagner, M.D., Ph.D., Kennedy Krieger Institute 3:00 p.m. 5:00 p.m. Small Group Break-out Sessions with Faculty 5:00 p.m. 7:00 p.m. Dinner 4

Schedule (continued) TUESDAY, JULY 21 7:00 a.m. 8:00 a.m. Breakfast 8:00 a.m. 8:45 a.m. Accelerating Clinical and Translational Science with Clinical Research Version 2.0 (Online/Mobile/User-Generated Participatory Research) Anthony S. Kim, M.D., University of California, San Francisco 8:45 a.m. 9:30 a.m. Working with Foundations and Patient Organizations Course Director, Craig Blackstone, M.D., Ph.D., National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH) 9:30 a.m. 10:15 a.m. How to Do Translational Neurology in Academia Barbara Slusher, Ph.D., M.A.S., Johns Hopkins University School of Medicine 10:15 a.m. 10:30 a.m. Break 10:30 a.m. 11:15 a.m. Getting and Staying Funded Justin C. McArthur, M.B.B.S., M.P.H., Johns Hopkins University School of Medicine 11:15 a.m. 12:00 p.m. The Role of the NIH in Translational Research Rajesh Ranganathan, Ph.D., National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health (NIH) 12:00 p.m. 1:30 p.m. Lunch 1:30 p.m. 2:15 p.m. Device Development Research in the Neurointensive Care Unit Romergryko G. Geocadin, M.D., Johns Hopkins University School of Medicine 2:15 p.m. 3:00 p.m. Epilepsy Research in the Neurointensive Care Unit Susan Herman, M.D., Beth Israel Deaconess Medical Center/Harvard Medical School 3:00 p.m. Closing Remarks and Departure 3:15 p.m. Adjourn 5

Mount Washington Conference Center Nestled among the hills just beyond the city limits of Baltimore, Maryland, Mt. Washington Conference Center and its historic octagon are a distinctive destination for meetings and events. Combining over a century of educational traditions with progressive design and technology, the center is an ideal setting for communicating and sharing ideas. Mt. Washington Conference Center offers a unique blend of being close to the city, yet it is country quiet. Nearby, enjoy the history, culture, attractions, and shopping of downtown Baltimore, the Inner Harbor, and the city s charming neighborhoods. Mt. Washington is conveniently located one hour from Washington, DC, and Northern Virginia. Hotel Highlights Minutes from Mt. Washington Village, featuring shopping and fine dining 20 minutes from downtown Baltimore and the Inner Harbor Fitness center, indoor basketball, and volleyball courts, a game room, and a jogging trail Baltimore/Washington International Airport (BWI) is within 35 minutes 10 minutes from Penn Train Station Mt. Washington Conference Center 5801 Smith Avenue Baltimore, MD 21209 Phone: 410-735-7964 Fax: 410-735-7907 Toll Free: 800-488-8734 Transportation to and from the Mt. Washington Conference Center Area Airports Mt. Washington Conference Center is approximately 35 minutes from the Baltimore/Washington International Airport. The conference center does not provide shuttle service from the airport. Ground Transportation The BWI Marshall Light Rail Station is located immediately outside the lower level of the terminal building, adjacent to Concourse E. The Light Rail Service is available for $1.60 each way and will exit at the Mount Washington Station stop. SuperShuttle is the leading airport shuttle company in the world and the leader in the Baltimore/Washington area. Counters are at the airport (located at lower level baggage claims 1 and 10). Anticipate shuttle fare of approximately $28 each way. Driving Directions from Baltimore/Washington International Airport (BWI) Take I-295 North to I-695 North (toward Towson) to I-83 South Take Exit 10 (Northern Parkway). Take Northern Parkway East Turn left at the light onto Falls Road Turn left at the light onto Kelly Avenue Veer right onto Greely Avenue Head straight into the Mt. Washington Conference Center Follow the driveway and turn at the second left. Park in guest parking lot. Enter the building marked Mt. Washington Conference Center. For a visitor s guide to Baltimore and surrounding areas, visit: baltconvstr.com or enjoybaltimorecounty.com 6

American Neurological Association s 7 TH ANNUAL Translational and Clinical Research Course for Clinician-Scientists July 19 21, 2015 Mt. Washington Conference Center, Baltimore, MD Applicant Information Deadline: May 31, 2015 Name LAST FIRST MIDDLE INITIAL CREDENTIAL(S) Institution Work Address 1 Work Address 2 City State Zip Phone Email Application Submission Deadline: May 31, 2015 A complete packet will include the following: 1. A complete application form. 2. A statement including: A short introduction of yourself and an outline of your current position, career plan, and clinical/translational research interest. Your career goals for the next 10 years. Your primary objectives for this course (what you hope to learn/accomplish). 3. A copy of your bio-sketch or CV with abbreviated bibliography. Course Agreement Please check each box below. If my application is accepted for the course, I understand that: Hotel accommodations for July 19 and 20, meals during the course, and all course materials will be provided at no cost by the ANA. I am responsible for all travel arrangements and fees including air, rail and, ground travel; baggage fees; meals purchased outside of the course; and tips and other incidentals. The application, statement and bio-sketch should be submitted electronically in an email to szuba@myana.org no later than May 31, 2015. Please note: If your packet does not include a personal statement and/or bio-sketch, the application will be incomplete and will not be considered. Or use the online form at: myana.org/7th-annual-tcrc-application-form. 7

American Neurological Association s 7 TH ANNUAL Translational and Clinical Research Course for Clinician-Scientists July 19 21, 2015 Mt. Washington Conference Center, Baltimore, MD myana.org/programs/translational-and-clinical-research-course