National Center for Genetic Engineering and Biotechnology (BIOTEC) Thailand

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1 National Center for Genetic Engineering and Biotechnology (BIOTEC) Thailand

2 BIOTEC Background and Mission Established in 1983 as a Research Centre Part of the National Science and Technology Development Agency (NSTDA) Operates outside the normal framework of civil service and state enterprises Main objectives induce dynamics of research and development through the application of biotechnology (research programs, research funding and research management) establish research laboratories with universities and government agencies human resource development, technical service, public awareness and international cooperation

3 NSTDA Organization (established by by a special law law in in 1991) NSTDA Board chaired by Minister of Science and Technology NSTDA BIOTEC MTEC NECTEC TMC NANOTEC NSTDA : National Science and Technology Development Agency BIOTEC : National Center for Genetic Engineering and Biotechnology MTEC : National Metal and Materials Technology Center NECTEC : National Electronics and Computer Technology Center NANOTEC: National Nanotechnology Center TMC : Technology Management Center

4 BIOTEC Research Units Chiang Mai Chiang Mai University Rice Gene Discovery Kasetsart University Khon Kaen Cassava/Starch R&D Kasetsart University Marine Biotech Chulalongkorn University Shrimp Molecular Biology Mahidol University Bangkok Biochemical Engineering KMUTT Medical Biotechnology Mahidol University Phuket Hat Yai Central Research Unit Science Park Peat Swamp & Tropical Rain Forest (Royal Forestry Department)

5 Distribution of R&D Funding* Rice Biotechnology Plant Biotechnology Shrimp Biotechnology Animal Biotechnology Bioprocess, Bioindustry, Novel Products, Food Innovation Medical Biotechnology Environmental Biotechnology and Sustainable Development Biotechnology for Rural Development * R&D budget distribution for FY 2005 (millions USD)

6 International Publications Intramural Extramural (Total 1040)

7 Research and Development Excellence and Relevance Rice Biotechnology Crop Improvement and Seed Technology Cassava Biotechnology Biodiversity/Biopesticies

8 International Rice Genome Sequencing Project (IRGSP) Chr.. 9

9 Marker Assisted Selection KDML Submergence + Bacterial Leaf Blight + brown planthopper + salt = super jasmine rice KDML105 +QTLsub +Xa21 KDML105 KDML105 +QTLsub +Xa21

10 Waxy Rice Rice Low-amylose Rice Rice High-amylose Rice Rice Breeding Rice Rice Variety for for Industrial Application

11 Cassava Molecular Biotechnology Consortium To understand the details of starch metabolism in cassava To produce novel cassava cultivars with high yielding, tailor-made starch [specific granule size]. high value cassava

12 Genome-wide analysis of cassava transcriptome Generation of cassava EST database Gene identification by Suppression Subtractive Hybridization Gene expression profile during storage root formation by cdna-aflp

13 Crop Improvement Papaya Ringspot Virus Resistance Resistant Papaya Susceptible papaya

14 Crop Improvement Tomato Yellow Leaf-Curl Virus Resistance ER1-19 (Delayed Symptoms) Susceptible Line Line ER1-16 (Resistant)

15 Biotechnology for Rural Development Rubber Plantation Etlingera elatior

16 Germplasm Collection and Breeding for New Varieties

17 Entomopathogenic Fungi

18 Paecilomyces lilacinus (( Meloidogyne spp.)

19 Germplasm Evaluation Rice: yield, disease (blast, bacterial leaf blight, rice-ragged stunt virus), nutrition Cassava: starch content, cyanide content, yield Corn: 25 characters (size, seed color, yield, disease, sweetness, tenderness) Sugarcane: yield, brix, number of stalks, stalk per stool, fiber Pepper: anthracnose, virus, fruitfly, capsaicin, early maturity, single harvest, indeterminate Tomato: color, sugar content, firmness and lycopene

20 International Collaboration - Regional Training Center in Biotechnology HRD Program for Neighboring Countries and the Pacific Islands Training Workshops and Short Courses Short and medium term training at BIOTEC laboratories (3-12 months) Operating since 2001 targeting Cambodia, Laos, Myanmar and Vietnam. Pacific Islands were added in 2005 with special funding from the New Zealand : 46 scholarships were awarded. At least six former trainees are now studying in Germany, Canada and AIT in Thailand.

21 International Collaboration - Regional Training Center in Biotechnology Plant Genetic Diversity Analysis and Marker-Assisted Breeding in collaboration with CGIAR (2005) Regional Training Workshop on GMO Testing in collaboration with FAO (2003) Regional Workshops on Molecular Breeding in Rice for Mekong Region in collaboration with Kasetsart University and the Rockefeller Foundation ( )

22 International Collaboration - Bilateral Collaboration Student exchange program MOU MOU --Tropical Biology and and Biotechnology Thermophilic enzymes USFDA Better Better Process Control School School Training Course Cosmetic research Drug Drug Discovery

23 National Center for Genetic Engineering and Biotechnology (BIOTEC) Thailand Responsible for research and development through the application of biotechnology Achieves this through research funding and management and the establishment of research laboratories with universities and government agencies Promotes capacity building through resource development, technical services, public awareness and international cooperation

24 National Center for Genetic Engineering and Biotechnology (BIOTEC) Thailand

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