FACULTY OF MEDICAL SCIENCE

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1 Doctor of Philosophy Program in Microbiology FACULTY OF MEDICAL SCIENCE

2 Naresuan University 171 Doctor of Philosophy Program in Microbiology The time is critical now for graduate education and research in Microbiology. Numerous professional careers are in demand in academic and industrial research, teaching, and services in public and private sectors where microbiology has an impact. The program supports a variety of research topics. However, the stars within our faculty are in the forefront, with co-operation from world-class researchers abroad, in the areas of Bacterial Antibiotic Resistance and Biodiversity, especially in the study of yeast as a microorganism. We are proud of our recipients of the Royal Golden Jubilee research grants awarded by the Thailand Research Fund.

3 172 Naresuan University Objectives The Ph.D. program in microbiology places emphases on research and training for professional careers in microbiology research and leadership. The specific objectives are listed below: To disseminate in-depth advanced knowledge in microbiology as a prerequisite to mastering systematic analytical thinking and competence in data synthesis as well as fostering an inquiring mind capable of self-directed life-long learning. To nurture skills and potential in microbiological inquiries leading to the development of modern technology. Skills acquired are for discovering new findings for sustainable development in societies and communities. To instill leadership with professional ethics so as to serve as a model in the society. Admission In accordance with the Graduate School Rules and Regulations. The program committee reserves the rights to require more qualifications as deemed appropriate. Medium of Instruction Thai and English

4 Naresuan University 173 Research Focus - Environmental Microbiology - Microbial Biology and Diversity - Molecular Medical Microbiology - Microbial Biotechnology - Immunology - Virology Requirement for Graduation In accordance with the Graduate School s Rules and Regulations.

5 Doctor of Philosophy Program in Microbiology FACULTY OF MEDICAL SCIENCE Naresuan University 577 Structure of the Program 1. Credit Requirements. * Requirements Option 1.1 Option 1.2 Option 2.1 Option 2.2 work Core s Electives Required Non-credit s Dissertation Total * Minimum credits required. 2. Core s Requirements Current Topics in Microbiology Advanced Microbial Physiology (or) Option 1.1 Option 1.2 Option 2.1 Option Medical Microbiology Biochemistry, Cell and Molecular Biology Total (or)

6 578 Naresuan University 3. Electives Requirements Option 1.1 Option 1.2 Option 2.1 Option 2.2 Advanced Diagnostic Medical Microbiology Advanced Microbial Forensics Molecular Pathogenesis of Bacteria Mechanism and Molecular Epidemiology of Drug-Resistant Bacteria Advanced Medical DNA Technology Advanced Bioinformatics Molecular Microbiology System Microbiology Molecular Biology of Microbial Photosynthesis Advanced Microbial Biotechnology Total Required Non-credit s. Option 1.1 Option 1.2 Option 2.1 Option 2.2 Requirements Research Methodology in Health Sciences Seminar Seminar Seminar Seminar Total

7 Naresuan University Dissertation Credit Requirements. Option 1.1 Option 1.2 Option 2.1 Option 2.2 Requirements Dissertation Dissertation Dissertation Dissertation Dissertation Dissertation Dissertation Dissertation Total

8 580 Naresuan University Descriptions Advanced Microbial Physiology 3(2-3-5) Recent aspects of advanced microbial physiology in biosynthesis and assembly of cell structures, bioenergetics, metabolism and regulation, regulation of growth of cells and cell cycles, morphogenesis, differentiation and development at molecular levels, and biological signal systems Medical Microbiology 3(2-3-5) Importance of microorganisms with emphasis on morphology, cultivation, physiology, pathogenesis, epidemiology, immunity to microbial infections, and laboratory diagnosis Advanced Bioinformatics 3(2-3-5) Evaluation of biological data using bioinformatics techniques including data collection, data analysis, data alignment, information technology applications in experimental designs, laboratory diagnosis, genetic relationship of organisms, protein identification, molecular modeling, methods to determine protein structure and other important aspects, and being knowledgeable in performing such analysis Advanced Diagnostic Medical Microbiology 3(2-3-5) Advanced techniques in identification of various pathogenic microorganisms, and application of molecular and immunological techniques for laboratory diagnosis of infectious diseases Advanced Microbial Forensics 3(2-3-5) Comprehensive study of the chain of custody in microbiological evidentiary materials, molecular methods and techniques for biotherat detection, and procedures for working high biosafety levels.

9 Naresuan University Molecular Pathogenesis of Bacteria 3(3-0-6) Recent aspects of bacterial pathogenesis with emphasis on molecular and genetic determinants, bacterial toxins, secretion systems, interaction with host bacterial cells and tissues, immune evasion, genetic regulation, exchange of virulence genes, the micro biome, antibiotic resistance, vaccines, and bioterrorism Mechanism and Molecular Epidemiology of Drug 3(3-0-6) Resistant Bacteria Mechanisms and molecular epidemiology of important drug-resistant bacteria with emphasis on gram negative bacteria producing extendedspectrum beta-lactamase (ESBL), Methicilin-resistant Staphylococcus aureus (MRSA), Penicillin-resistant Streptococcus pneumonia (PRSP), multiple drug-resistant of diarrheal pathogens Pseudomonas aeruginosa, and Acinetobacter species Advanced Medical DNA Technology 3(2-3-5) Principles of DNA technology in therapeutics and diagnostics; applications of molecular biology techniques and recombinant DNA technology including genes cloning, gene expressions, animal models and PCR-based techniques in diagnosis and gene therapy; and key ideas of the recent research on genes transfers, vector development, and pre-clinical research Molecular Microbiology 3(2-3-5) Microorganisms at molecular level in biochemistry, physiology, classifications and identifications, laboratory diagnosis, and their applications using advanced DNA technology.

10 582 Naresuan University System Microbiology 3(2-3-5) Integrated and basic biological knowledge of microorganisms in biochemistry, genomics, transcriptomics, metabolomics and proteomics, and descriptions of microbial cells functions with emphasis on the balance between microbes and humans Molecular Biology of Microbial Photosynthesis 3(2-3-5) Photosynthetic patterns in various groups of microorganisms, cellular structure of photosynthetic apparatus, molecular structure and biosynthesis of photosynthetic pigments, mechanisms of electron flow in electron transport chain, bioenergetics and metabolic processes, and regulations and genes involved in microbial photosynthesis Current Topics in Microbiology 3(3-0-6) Discussion and practice in oral presentations of current trends and issues in microbiology Advanced Microbial Biotechnology 3(2-3-5) Microbial importance in advanced biotechnology, strain selection and improvement, fermentation processes, bio separation of microbial products, applications of microorganisms and their products in industry, environment, pharmacy, medicine, agriculture, and alternative energy production Dissertation I, Option Credits Identifying the research question, writing a research proposal describing the significance and purposes of the study, and research methodologies in brief including an extensive review of the literature.

11 Naresuan University Dissertation II, Option Credits Submission of the dissertation supervisory committee to the Graduate School and submission of the dissertation title to advisors Dissertation III, Option Credits Conducting an extensive research, reporting progress of the research to the dissertation advisors, and taking the qualifying examination Dissertation IV, Option Credits Conducting an extensive research, reporting progress of the research to the dissertation advisors, and taking the dissertation proposal defense examination Dissertation V, Option Credits Conducting an extensive research, reporting progress of the research to the dissertation advisors, and preparing a scientific manuscript for publication under a standard peer-review process Dissertation VI, Option Credits Summarizing all research data, passing the dissertation defense, complying with dissertation corrections if any, and submitting the completed dissertation to the Graduate School Dissertation I, Option Credits Identifying the research question, writing a research proposal describing the significance and purposes of the study, and research methodologies in brief including an extensive review of literature Dissertation II, Option Credits Submission of the dissertation supervisory committee to the Graduate School and submission of the dissertation title to advisors.

12 584 Naresuan University Dissertation III, Option Credits Conducting an extensive research and taking the qualifying examination Dissertation IV, Option Credits Conducting an extensive research, reporting progress of the research to the dissertation advisors, and taking the dissertation proposal defense examination Dissertation V, Option Credits Conducting an extensive research and reporting progress of the research to the dissertation advisors Dissertation VI, Option Credits Conducting an extensive research and reporting progress of the research to the dissertation advisors Dissertation VII, Option Credits Collecting research data and preparing a scientific manuscript for publication under a standard peer-review process Dissertation VIII, Option Credits Summarizing all research data, passing the dissertation defense, complying with dissertation corrections if any, and submitting the completed dissertation to the Graduate School Dissertation I, Option Credits Submission of the dissertation supervisory committee to the Graduate School and submission of the dissertation title to advisors Dissertation II, Option Credits Conducting an extensive research, reporting progress of the research to the dissertation advisors, and taking the qualifying examination.

13 Naresuan University Dissertation III, Option Credits Conducting an extensive research, reporting progress of the research to the dissertation advisors, taking the dissertation proposal defense examination, and preparing a scientific manuscript for publication under a standard peer-review process Dissertation IV, Option Credits Summarizing all research data, passing the dissertation defense, complying with dissertation corrections if any, and submitting the completed dissertation to the Graduate School Dissertation I, Option Credits Identifying the research question writing a research proposal describing the significance and purposes of the study, and research methodologies in brief including an extensive review of the literature Dissertation II, Option Credits Submission of the dissertation supervisory committee to the Graduate School and submission of the dissertation title to advisors Dissertation III, Option Credits Conducting an extensive research and taking the qualifying examination Dissertation IV, Option Credits Taking a dissertation proposal defense examination, conducting an extensive research, and reporting progress of the research to the dissertation advisors Dissertation V, Option Credits Collecting research data and preparing a scientific manuscript for publication under a standard peer-review process.

14 586 Naresuan University Dissertation VI, Option Credits Summarizing all research data, passing the dissertation defense, complying with dissertation corrections if any, and submitting the completed dissertation to the Graduate School Seminar I 1(0-2-1) Extensive practice in searching, reading, critical thinking, and organization of information from articles or published papers, and oral presentation practice on selected and current topics in microbiology Seminar II 1(0-2-1) Report and discussion on selected and current trends in advanced microbiology Seminar III 1(0-2-1) Seminar on selected and current trends in microbiology Seminar IV 1(0-2-1) Seminar on selected topics in microbiology related to the doctoral dissertation Research Methodology in Health Sciences 3(3-0-6) Definitions, characteristics and goals of research, research methodologies, types of research, determination of research questions, variables and hypothesis, data collection, data analysis, research proposal and research report writing, research evaluation, research applications, ethics in research, and advanced research techniques in health sciences.

15 Naresuan University Biochemistry, Cell and Molecular Biology 3(3-0-6) Cells and cell cycles, properties and structures of major biomolecules, protein structures and functions, enzymes and kinetics, bioenergetics and metabolism of biomolecules, genomes organization, replications, DNA damage and repair, transcription and translation processes, bioinformatics, molecular biology, biochemistry of endocrines, and significant perspectives in biochemistry.

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