Congress Cochairs Artemis P. Simopoulos, MD (USA) Raffaele De Caterina, MD, PhD (Italy)

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1 1 st Congress of the International Society of Nutrigenetics/Nutrigenomics Hellenic American University/Hellenic American Union 22 Massalias Street Athens, Greece November 11 13, 2007 Congress Cochairs Artemis P. Simopoulos, MD (USA) Raffaele De Caterina, MD, PhD (Italy) Scientific Committee Raffaele De Caterina, MD, PhD (Italy) Michel de Lorgeril, MD, PhD (France) Serge Ferrari, MD (Switzerland) Steve E. Humphries, PhD (UK) Jing X Kang, MD, PhD (USA) Ronald Krauss, MD (USA) Sergio Muntoni, MD (Italy) Jose Ordovas, PhD (USA) Marjanne Senekal, PhD (South Africa) Gérard Siest, PhD, PharmD (France) Artemis P. Simopoulos, MD (USA) Lisa Spence, PhD (USA) Philippa J. Talmud, PhD (UK) Antonio Velazquez, MD, PhD (Mexico) Nikos Yiannakouris, PhD (Greece) Congress Cosponsors International Society of Nutrigenetics/Nutrigenomics (ISNN) The Center for Genetics, Nutrition and Health (USA) Hellenic American University/Hellenic American Union (HAU/HAU, Greece) Harokopio University (Greece) Belovo Columbus Concept (Belgium) National Dairy Council (USA) Nutrilite Health Institute (USA) Nestlé SA (Switzerland) Organized by International Society of Nutrigenetics/Nutrigenomics The Center for Genetics, Nutrition and Health Hellenic American University/Hellenic American Union 1

2 DEDICATION This congress is dedicated to the Concept of Positive Health articulated by Hippocrates 2500 years ago, which is based on the interaction of genetics, diet and physical activity: 'Positive health requires a knowledge of man's primary constitution (which today we call genetics) and of the powers of various foods, both those natural to them and those resulting from human skill (today's processed food). But eating alone is not enough for health. There must also be exercise, of which the effects must likewise be known. The combination of these two things makes regimen, when proper attention is given to the season of the year, the changes of the winds, the age of the individual and the situation of his home. If there is any deficiency in food or exercise the body will fall sick.' (5 th Century BC) 2

3 1 st Congress of the International Society of Nutrigenetics/Nutrigenomics Hellenic American University/Hellenic American Union (HAU) 22 Massalias Street Athens, Greece November 11 13, :00 7:00 p.m. Registration Sunday, November 11, 2007 HAU Auditorium 7:00 7:30 p.m. Welcoming Remarks Artemis P. Simopoulos, President, ISNN Chris Spirou, President, HAU/HAU Leonidas Koskos, Executive Director, HAU/HAU Nikos Yiannakouris, ISNN, Harokopio University 7:30 9:00 p.m. Reception Hellenic American Union, 8 th Floor Monday, November 12, 2007 HAU Auditorium 7:30 8:30 a.m. Registration Hellenic American Union Plenary Lectures 8:30 9:15 a.m. Opening Address: Nutrigenetics/Nutrigenomics Nutritional Implications Artemis P. Simopoulos, MD (USA) 9:15 10:00 a.m. Nutriepigenomics: A Lifelong Stochastic, Genetic and Environmental Remodeling of our Epigenomes Claudine Junien, MD (France) 10:00 10:30 a.m. Coffee Break 10:30 11:00 a.m. Proteomics Strategies and Applications for Nutritional Research Gilbert S Omenn, MD, PhD (USA) 11:00 11:30 a.m. Metabolomics in Health and Disease David Mutch, PhD (France) 3

4 11:30 12:00 p.m. Role of Nutrients in Gene Expression Omega-3 Fatty Acids and the Regulation of Endothelial COX-2 Raffaele De Caterina, MD, PhD (Italy) 12:00 2:00 p.m. Lunch and Poster Session Session I: Genetic Variation and Dietary Response in Cardiovascular Disease Cochairs: Philippa J Talmud, PhD (UK) Jose Ordovas, PhD (USA) 2:00 2:20 p.m. Gene:Environment Interaction on Coronary Heart Disease Risk Philippa Talmud, PhD (UK) 2:20 2:40 p.m. Genetic Variation, Omega-3 Fatty Acids and Heart Disease Jose Ordovas, PhD (USA) 2:40 2:50 p.m. A Nutrigenomics Approach to Define a Lifestyle Algorithm to be used in Cardiovascular Disease Prevention, Diagnosis and Therapy Hans-Richard Brattbakk (Norway) 2:50 3:00 p.m. Nutriepigenomics of Metabolic Syndrome Ondrej Seda, MD (Czech Republic) 3:00 3:15 p.m. Discussion Discussant: Ronald Krauss, MD (USA) 3:15 3:45 p.m. Coffee Break 4:00 5:00 p.m. Poster Session Congress Participants 4:00 5:30 p.m. Board of Directors Meeting ISNN Board Members 5:30 6:30 p.m. Business Meeting - ISNN Membership HAU Auditorium 7:00 9:00 p.m. Banquet Buffet Hellenic American Union, 8 th Floor Tuesday, November 13, 2007 Session II: Gene-Nutrient Interactions and Hypertension Cochairs: Steven C Hunt, PhD (USA) Steve Humphries, PhD (UK) 8:00 8:20 a.m. Dietary Manipulation, Pharmacogenetics, and Genetic Interactions Reveal Defective Genetic Control of Blood Pressure Steven C Hunt, PhD (USA) 4

5 8:20 8:40 a.m. Variability Genes, Blood Pressure and Coronary Heart Disease Risk Steve Humphries, PhD (UK) 8:40 8:55 a.m. Discussion Discussant: Steve Humphries, PhD (UK) 8:55 9:15 a.m. Special Presentation: Variants in Genes of Metabolic and Signaling Pathways Impacted by Lipid-Based Molecules and Their Association with Age-Related Macular Degeneration John Paul SanGiovanni, ScD (USA) Sesson III: Gene-Nutrient Interactions and Osteoporosis Cochairs: Serge Ferrari, MD (Italy) Gerard Siest, PhD, PharmD (France) 9:15 9:35 a.m. Bone Mass Regulation by Leptin and Leptin Receptor Polymorphisms Serge Ferrari, MD (Italy) 9:35 9:50 a.m. Discussion Discussant: Gerard Siest, PhD, PharmD (France) 9:50 10:10 a.m. Special Presentation: EUROGENE eten Consortium to Provide Nutrigenetic E-Services Keith Grimaldi, PhD (UK) 10:10 10:40 a.m. Coffee Break Session IV: Genetics of Obesity Cochairs: Louis Perusse, PhD (Canada) George Chrousos, MD (Greece) 10:40 11:00 a.m. Genetics of Obesity: The Role of Gene-Nutrient Interactions Louis Perusse, PhD (Canada) 11:00 11:20 a.m. Anti-inflammatory Diet: Search for Anti-inflammatory Phenotype Dimiter Dimitrov, MD, PhD (Bulgaria) 11:20 11:40 a.m. Predictive Genomics for Determining Genetic Predisposition to Obesity Marios Kambouris, PhD (Greece) 11:40 11:50 a.m. ADIPOQ Gene tagsnp Associations with Serum Adiponectin in Normal Women and Tests of Promoter Activity Theodosios Kyriakou, MD (UK) 11:50 12:00 p.m. Association Between Glutamate Decarboxylase 2 (GAD2) and Binge Eating in Obese Children: Results from the Gendai Study Maria Tzirkalli (Greece) 5

6 12:00 12:15 p.m. Discussion Discussant: George Chrousos, MD (Greece) 12:15 2:00 p.m. Lunch and Poster Session Session V: Genetics of Cancer Cochairs: Michel de Lorgeril, MD, PhD (France) Antonio Velazquez, MD, PhD (Mexico) 2:00 2:20 p.m. Gene-Alcohol Interactions and Cancer Michel de Lorgeril, MD, PhD (France) 2:20 2:40 p.m Frontiers in Nutrigenetics/Nutrigenomics at the National Cancer Institute (NCI- NIH) John A Milner, PhD (USA) 2:40 3:00 p.m Genetic Variation, Omega-6 Fatty Acids and Prostate Millie Hughes-Fulford, PhD (USA) 3:00 3:15 p.m. Apolipoprotein E (Apo E) Genotypes, Alcohol Consumption and Risk of Sporadic Distal Colorectal Adenomas Panagiota Mitrou, PhD (UK) 3:15 3:30 p.m. Discussion Discussant: Antonio Velazquez, MD, PhD (Mexico) Session VI: Genetics of Diabetes Cochairs: Sergio Muntoni, MD (Italy) Jing Kang, MD, PhD (USA) 3:30 3:50 p.m Insulin Resistance Sergio Muntoni, MD (Italy) 3:50 4:10 p.m. Association Between the Risk of Type 2 Diabetes and Variants in Genes Involved in Beta-Cell Function and Hepatic Gluconeogenesis in a Chinese Han Population Xu Lin, MD (China) 4:10 4:30 p.m. The Effect of Conjugated Linoleic Acid on Gene Expression of Resistin and Adiponectin in Obese Rats Fed With CLA Chang-Hao Sun, PhD (China) 4:30 4:45 p.m. Discussion Discussant: Jing Kang, MD, PhD (USA) 4:45 5:00 p.m. Coffee Break Session VII: Industry and Consumers What is the Business Model for Personalized Nutrition and Medicine? Cochairs: Lisa Spence, PhD (USA) Marjanne Senekal, PhD (South Africa) 6

7 5:00 5:15 p.m. Commercial Nutrigenetic Anti-inflammatory Products Ken Kornman, PhD (USA) 5:15 5:30 p.m. The Columbus Concept: a Business Model for Personalized Nutrition & Medicine Fabien de Meester, PhD (Belgium) 5:30 5:45 p.m. An Industry Perspective on Nutrigenomics Laurent B. Fay, PhD (Switzerland) 5:45 6:00 p.m. Nutrigenetics & New Market: Customizing Health Care Catia Cale (Portugal) 6:00 6:15 p.m. A Case in Commercial Applications of Nutrigenetics Serdar Savas, MD (Turkey) 6:15 6:30 p.m. Consumer Perspective on Nutrigenomics Sylvia Rowe, PhD (USA) 6:30 6:45 p.m. Discussion Discussant: Marjanne Senekal, PhD (South Africa) 6:45 7:00 p.m. Closing Remarks Artemis P Simopoulos, MD (USA) Congress Adjourns 7

8 Congress Information Venue Hellenic American University/Hellenic American Union 22 Massalias Street Athens, Greece Phone: Fax: Web: (Just a few minutes' walk from the PANEPISTIMIO subway station) Abstracts Deadline for Abstracts to be considered for Oral Presentation was July 31, However, Abstracts for Poster Presentation will continue to be accepted until September 30 th. See instructions on the ISNN website: Registration Registration fee before September 30, 2007 Registration fee ISNN regular member - USD 300 Registration fee ISNN associate member USD 200 (student, fellow, trainee, technician) Registration fee ISNN corporate/industry member - USD 400 Registration fee non member* - USD 500 Registration fee after September 30, 2007 Registration fee ISNN regular member - USD 400 Registration fee ISNN associate member USD 300 (student, fellow, trainee, technician) Registration fee ISNN corporate/industry member - USD 500 Registration fee non member* - USD 600 * You may join ISNN as a member before registering for the congress see society website to join Congress registration includes: Entry into all scientific sessions Program and abstract book Lunch, mid-morning and mid-afternoon coffee and tea on all congress days Reception and Banquet 8

9 Hotel Please complete the required form found on the ISNN website ( and return back by fax no later than September 30 th to: BEST WESTERN ESPERIA PALACE HOTEL 22, STADIOU STR ATHENS- GREECE TEL FAX info@esperiahotel.com.gr 9

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