An Introduction. SEPRACOR Information Technologies

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1 An Introduction

2 Overview Research-based Pharmaceutical Company Founded in 1984 as Separations Company Public Trading & Pharmaceutical Focus started in ,600+ Employees as of 1 June, Corporate 2,000 Field Sales Representatives; 4 Regional Sales Offices Headquarters in Marlborough, MA Routes 290 & 495; 85 Acre Campus Manufacturing site in Windsor, NS, Canada

3 Overview (continued) Therapeutic Focus: Respiratory & CNS Three Licensed Products: Allegra (Licensed to Sanofi-Aventis) Xyzal /Xusal (Licensed to UCB Pharma) Clarinex (Licensed to Schering-Plough) Four Labeled Products: Xopenex (Launched in 2000) Xopenex HFA MDI (Launched in 2006) Lunesta (Launched in 2004) Brovana (Approved October, 2006 for Launch in 2007) Future Products: Various Other Compounds (Phase II, IND-Track; Preclinical)

4 Overview (continued) Product Development Strategy: Single Isomer & Improved Chemical Entities New Drug Development; Drug Discovery Co-Development & Compound Licensing Product Sales Strategy: Direct Sales (General and Specialty Sales Forces) Out-licensing (Domestic & International) Co-promotion Growth Plan: Controlled Staff Growth Outsourcing / Partnerships: R&D Manufacturing, Clinical Acquisition

5 Information Technologies Current Staff: 50 FTE & 4 F/T Contractors One of the Lowest Staff Turnover Ratios in Company 16 New Hires in 2006 Organization: 4 Departments Operations (DB, Web, Data Center, Validation) Networking & Telecommunications Desktop Services Business Applications Support IT Culture & Environment Team & Task Orientation Focus on Training (Technical & Soft Skill) Cross-Business Area Assignments Focus on Redundancy & Reliability Excellent Senior Management Support Full IT Responsibility Across the Corporation

6 Information Technologies (continued) Services Architecture: 3 Tier Enterprise: Sun Solaris; Linux (Sparc & Intel) Workgroup / Mid-Tier: Windows Server; Linux (Intel) Desktop: Windows (Intel) FDA Validated Systems Application Architecture: Enterprise Best of Breed Oracle 11i ERP (All Modules) Documentum / imany CARS / iet IEnterprise Oracle Clinical / Oracle AERS / Oracle TMS Informatica / Microstrategy / Hyperion Essbase Cambridgesoft R&D Suite / LabVantage LIMS Outsourcing: Service-based (Field Help Desk; PC Application Support; DRP) Application-based (PSFA, Specialized Medical Marketing) IT Budget (FY2006): 3.2% to 3.5% of Corporate Expense spend

7 Outlook 2006/2007 Products: Enhance Market Share for Branded Products Launch Lunesta in Europe & Japan Gain FDA Approval for Arformoterol Phase III/B4 Co-Morbidity Studies for Lunesta Enhance Portfolio New Candidates Acquisitions IT Data Warehousing / BI / CBA Knowledge/Document Management Infrastructure Upgrades B2B; ecommerce; eregulatoryreporting IT Process Management & Governance Regulatory Compliance

8 The ERP ROI Saga

9 ERP - Return On Investment Not An Initial Consideration! ROI Not the Right Measurement! Infrastructure System Business Critical Benefits: Staff Expansion Avoidance Business Flexibility Improved Process Management Transactional Volume Increases Additional Product Introductions Supply Chain Growth Very Successful Implementation!

10 ERP Timeline Oracle Clinical Oracle RDBMS Started 1998 ERP Replacement Project Project Approval 6/1999 Replace Client/Server System (Solomon) Prepare for Commercialization RFI Issued 12/1999 Vendor Selection 3/2000 Go Live All Modules 1/2001

11 ERP Costs Initial Software: $520K Hardware: $750K Services: $1.6M Oracle Consulting as Primary Implementation Partner Annual New License Purchases: $250 - $500K Maintenance: $340K Hardware: $100K

12 ERP Vendor Selection Criteria: Met Business Requirements Class A System & Vendor Life Sciences Experience Expandability (MFG, Multi-Org, etc.) Direct Vendor Support Players: SAP Oracle Siebel Solomon (Great Plains / Microsoft)

13 ERP Current Status Modules (Version ) Financials HR & Benefits (Self Service) Order Processing Projects; Time & Labor Process Manufacturing (Inventory) Futures: Version Upgrade to New Modules: Procurement Manufacturing Treasury; Multi-Currency Financial EIS (Essbase) Oracle Fusion

14 Thank You!

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