Please save the date and we are looking forward to seeing you in stanbul 2015.

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1 Announcement

2 Welcome to stanbul On behalf of the Organizing Committee of the 1 st PHARMACOGENOMICS STANBUL SUMMIT, Increasing the Safety and Effectiveness of Personalized Therapy for Metabolic Disorders it is my great pleasure and honor to welcome you to stanbul for the first edition of this summit series, to provide a platform to discuss the impact of pharmacogenomics in personalized healthcare. Pharmacogenomics studies and applications are important because of ethnic and cultural diversity, but also socio-economical, scientific and technological disparities over the world. The Summit covers these aspects, but also takes on a more global approach on the growing contribution of genomic information and biotechnological tools to the way medicines used in Metabolic Disorders are prescribed to patients, and as a consequence, how they are developed in industry. We will develop a scientific program of the highest standard covering keynote lectures by international experts, sessions of debates on the implementation of pharmacogenomics in clinical practice and a poster session, to which we encourage the submission of high quality abstracts. The Organizing Committee is also planning a special meeting which will give the opportunity for interaction among senior and junior researchers, medical, regulatory and industry experts in a wide range of disciplines linked to pharmacogenomics and personalized medicine. The Summit is a key activity for a growing network of professionals interested in the personalized therapy and pharmacogenomics knowledge for Metabolic Disease. The conference will be attended by a wide range of participants: pharmacists, biochemists, clinical pharmacologists, medical and molecular biologists, molecular geneticians, epidemiologists, bioinformatics experts, physicians expertised in cardiology, endocrinology, surgery (bariatric and general) and neuropsychiatry, family physicians, public health professionals, medical, regulatory and industry experts from Turkey, nearest countries and Europe. Please save the date and we are looking forward to seeing you in stanbul Prof. Dr. Belgin SÜSLEY C DUMAN Society of Pharmacogenomics and Personalized Therapy President 2

3 CONGRESS COMMITTE President Prof. Dr. Belgin Süsleyici-Duman Secretary Prof. Dr. Vangelis G. Manolopoulos Prof. Dr. Nevrez Koylan SCIENTIFIC COMMITTEE Prof. Dr. Belgin Süsleyici-Duman Prof. Dr. Gérard Siest Prof. Dr. Vangelis G. Manolopoulos Prof. Dr. Sophie Visvikis-Siest Prof. Dr. Ron HN van Schaik Prof. Dr. Munir Pirmohamed Prof. Dr. Ann.K.Daly Prof. Dr. Maurizio Simmaco Prof. Dr. Sevim Rollas Prof. Dr. Taner Damc Prof. Dr. Mustafa Taflk n Prof. Dr. Muhsin Konuk Prof. Dr. Kemal Sami Korkmaz Prof. Dr. Ahter Dilflad fianl o lu Prof. Dr. Melek Öztürk Prof. Dr. Ya z Üresin Prof. Dr. Nevrez Koylan Prof. Dr. Selma Y lmazer Prof. Dr. Çavlan Çiftçi Prof. Dr. Adnan Ayd n Prof. Dr. Burak Erman Prof. Dr. Turgut Ulutin Prof. Dr. Ayfle Özer Assoc. Prof. Dr. Devrim Gözüaç k Dr. Mehmet Gökhan Kara 3

4 LOCAL ORGANIZING COMMITTEE Prof. Dr. Belgin Süsleyici-Duman Prof. Dr. Nevrez Koylan Prof. Dr. Taner Damc Prof. Dr. Mustafa Taflk n Prof. Dr. Muhsin Konuk Prof. Dr. Çavlan Çiftçi Prof. Dr. Sevim Rollas Assoc. Prof. Dr. Selen Yurdakul Dr. Mehmet Gökhan Kara Dr. Güler Dartan MSc. Meliha Koldemir-Gündüz Bio. Mehtap Çevik 4

5 The main scientific programme will be held on November 27/ The aim is to have Experts presenting novel knowledge on the role, importance and applications Pharmacogenetics and personalized Therapy Metabolic Disorders in relevance to clinical project. Novel Tools and Technologies in Personal Omics Research Implementation of Personalized Medicine Strategy for Cardiovascular, Metabolic Disorders and Neuropyschiatric Disease Applications of Pharmacogenetics in Clinical Practice, Current Status Personalized Medicine and Health Care Management Personalized Medicine and Biologics Targeted Therapy of Metabolic Syndrome and it s Components Challenges in Pharmacogenomics for Therapeutic Product Development Regulatory Frontiers in Personalized Medicine Epigenomics of Drug Transporters 5

6 Registration And Accommodation Registration And Accommodation Those who wish to participate to the congress are kindly asked to duly fill in the enclosed Registration and Accommodation Form and together with the necessary payment documents send it to the organizing secretariat via fax or mail no later than August 15, The Registration Fee Includes : Early Registration Before August 15, 2015 Late Registration After January 15, 2015 Member ESPT/TSPPT 180.-Euro 200.-Euro Non Member 250.-Euro 275.-Euro Primary Care Doctor 60.-Euro 75.-Euro Assistant 50.-Euro 60.-Euro Student 35.-Euro 40.-Euro Exhibitor 50.-Euro 75.-Euro Accompanying Person 50.-Euro 50.-Euro For Members ESPT/TSPPT, Members National Societies, Non Members: Participation to all scientific sessions, admission to the scientific and commercial exhibition, All the congress documentation ( participant name tag, pocket programme, final programme booklet, abstract book, certificate of attendance, congressbag.) Accompanying Persons: Accompanying name tag Hotel Single Room Before Per Person in Double Room Single Room After Per Person in Double Room Kozyata Hilton 100.-Euro 60.-Euro 120.-Euro 80.-Euro * The prices include 2 nights Bed & Breakfast accommodation ( V.A.T. not included) Hotel reservations will be made on first come first served basis. The Organizing Secretariat reserves the right to book another hotel if the requested Hotel is fully booked. Payment The payment transfer form should clearly state the name(s) of the participant(s) and 1st PHARMACOGENOMICS STANBUL SUMMIT 2015 The registration fee should be paid to the bank account stated below. Bank Name : TÜRK EKONOM BANKASI Swift Code : TEBUTRIS391 City : STANBUL Account Name : Semtur Seminer Kongre Turizm Org. Tic. Ltd. fiti. Account No : (Euro) Euro IBAN : TR Account No : (YTL) TL IBAN : TR Congress Organizations Services Semtur Seminer Kongre Turizm Org. Tic. Ltd. fiti Refund of fee, less a 25% administrative charge, will be applied to cancellations before August 15, Refund of fee, less a 50 % administrative charge, will be applied to cancellations before August 15, As August 15, 2015 no refund will be made. Any money transfer deduction will be charged on arrival. After August 15, 2015 no name changes will be accepted. 6

7 Abstract Submission Abstract Submission ABSTRACT SUBMISSION TO 1st PHARMACOGENOMICS STANBUL SUMMIT 2015 The Scientific Program Committee cordially invites authors to submit abstracts for oral and poster presentation. Important dates are as follows: Deadline for submission of abstracts September 18, 2015 Announcement of the results (accept or reject) October 16, 2015 Deadline for author registration October 30, 2015 Abstracts should be sent via to by September 18, 2015 using the congress template Abstract Form 2015, in accordance with the following rules. Abstract Form 2015 can be downloaded from: www. pharmacogenomicsistanbul.com Guidelines for Abstract Submission The submission of an abstract implies its author(s) willingness to participate in the 1st PHARMACOGENOMICS STANBUL SUMMIT 2015 and his/her/their acknowledgement of the abstract s publication in the Congress Abstract Book, then in a special edition/supplement of a scientific journal. The abstract and its content should be original. It should not have been presented elsewhere previously, and it should not have been produced from a previously published paper. This property of the abstract will be checked by using special soft ware s and web services (similarity check). The abstract submitted should be in English, in the Microsoft Word format as in the attached Abstract Form 2015, and not exceed a maximum of 400 words. The abstract should be structured as: Background, Aim, Methods, Results, Discussion, and Conclusion, as in the Abstract Form The primary, the presenting, and the corresponding (i.e., submitting) author of the abstract can be different. All these information should be stated in the abstract form. It is the responsibility of the authors to ensure the accuracy of the abstract. At least the presenting authors of the accepted abstract should register to the congress and attend. Authors may send modification requests regarding their submitted abstracts until the submission deadline. There will be no additional editing after the deadline. Authors should state their preference of presentation type (oral or poster). However, the Scientific Program Committee will make the final decision after evaluation. A maximum of 2 tables can be embedded into the abstract form along with their legends. Figures, graphics and photographs should be sent as separate files (in TIFF or JPEG format). They should not be embedded into the abstract form. The minimum resolution of the figures should be 300 dpi, and its dimentions should be at least 8x8 cm. Figure legends should be listed at the end of the abstract form. Evaluation Process: All submitted abstracts will be reviewed by the Scientific Program Committee according to a standard review procedure. Notification of acceptance will be sent by to the corresponding (submitting), and presenting author. If the presenting author of an accepted abstract does not register until the author registration deadline, the abstract will be removed from the scientific program. 7

8 Important Dates Important Dates Deadline for submission of abstracts September 15, 2015 Deadline for registration at the reduced fee August 15, 2015 Deadline for accommodation at the reduced rate August 15, 2015 Correspondence Addresses Correspondence Addresses Scientific Secretariat Prof. Dr. Belgin Süsleyici-Duman MARMARA UNIVERSITY T: T: Organizing Secretariat Professional Congress Management Company SEMTUR Seminar Congress Organization T: F:

9 Congress Date November 27/28, 2015 Congress Place Congress Venue Organizing Society stanbul - TURKEY Hilton stanbul Kozyata na Society for Pharmacogenetics and personalized Therapy Estimated Participants 250+ Organization Company Congress Language Registration Name Badge Certificate of Attendance Exhibition Area Invitation Letter Visa requirement Insurance SEMTUR Professional Congress Management Company The official language of the congress is English. Turkish translation will be provided. Registration and information desks will be open at the congress hotel starting at November 26, 2015 throughout the congress between 08:00-18:00. All participants and guests shall wear their ID badges during the entrance of congress venue, at the scientific presentations, exhibition areas and other social programs. A certificate of attendance will be presented to all registered participants upon completion of evaluation forms. During the congress, pharmaceutical and medical device companies will exhibit their products at the convention center in the area allotted to them. Exhibit space will be open for the entire convention. Congress participants who have completed the registration process, a letter of invitation will be sent on demand in order to help them to obtain visa and/or permission from their institutions. Participants are requested to check with the Turkish Consulate in their home country or with their travel agency or at for visa requirements. Entry visa to Turkey can also be obtained at stanbul Atatürk Airport for a number of countries. The conference participants are not covered by any insurance (travel, medical, accident or liability) provided by the Conference Organizers. The Conference Organizers cannot accept liability for any loss or damage suffered by any participant or accompanying person or other person during travel to and from the conference or during the conference. Participants are advised to consider getting their own travel insurance and to extend their personal policy to cover personal possessions. 9

10 Climate Electricity Currency, Banks and Exchange Facilities Credit Cards Telephones Time Tipping stanbul Restaurants and Turkish Cuisine The average temperature in stanbul during November C at daytime. Turkey operates on 220 volts, 50 Hz, with round-prong Europeanstyle plugs that fit into recessed wall sockets /points. An adapter could be obtained from the hotel reception. The Turkish currency is Turkish Lira. As of April 2015, the exchange rate is: 1 Turkish Lira = 0.36 Euro. Foreign money can be changed at banks during normal business days ( Monday-Friday) as well as at hotels, at the airport and in exchange offices. Exchange rates are set daily by the Central Bank. Automated bank machines are available at many points throughout the city and at the airport. All major credit cards (Visa, Master Card) are accepted in Turkey by restaurants, hotels, shops and at the Conference Registration Desks. Pay phones (operated by hotel registration) are available at the meeting hotel. Turkey is in the Eastern European Time Zone, thus 2 hours ahead of Greenwich Mean Time (GMT+2). Although service charge is included in most restaurants, leaving a tip at one's own discretion is appreciated. The strategic setting of stanbul, the only city in the world built on two continents, has formed its destiny as an imperial capital for 1600 years. From the empires of Roman, Byzantine and Ottoman, this metropolis with its rich history and natural beauty, offers a friendly welcome and genuine hospitality. Numerous museums, ancient churches, synagogues, basilicas, mosques, mausoleums, palaces, bazaars and baths are standing today as the pride of all civilizations. With more than ten universities and many institutions, stanbul is the most important centre of Turkish science and culture. There is a wide choice of restaurants in stanbul offering a broad spectrum ranging from excellent national cuisine to first class international dishes. Traditional Turkish cuisine is famous for its many specialties prepared with fresh vegetables. There are lots of quality restaurants as well as fast-food shops in the vicinity of the hotels reserved for this meeting. 10

11 Shopping Travel within stanbul How to Get Around in stanbul stanbul Kart One of the most enjoyable parts of a trip to Turkey is shopping for the rich variety of Turkish crafts. stanbul is a shopping paradise with its Covered Bazaar as well as the modern malls. Turkish carpets, kilims, suede and leatherwear as well as other items of clothing are the best buys. Copper, silver, brassware and jewellery are also choices for buying, along with works of ceramics and the famous Turkish meerschaum. In the Covered Bazaar bargaining over the sale price with shop traders is expected. Public boats which depart from Besiktas, Eminonu, Karakoy on the European Side and Kadikoy, Uskudar, Bostanci on the Asian Side. Please refer to the hotel concierge for more information while planning your trip within the city. First and foremost, we recommend purchasing an stanbul Kart to save you money on public transportation. The stanbul Kart is a card that discounts your fare and now on many of the transportation methods including on ferries, metro and buses, you can only pay electronically which means that you have to use one of the approved passes, not a credit or debit card. If you don t have one, you are going to have to ask people on the bus if they have enough money preloaded onto their card and if a nice and willing person does, they can swipe their card for you and can pay them the fare amount. The stanbul Kart is only 6 TL plus whatever amount you wish to load onto the card. When you use the card you get a 10% discount off the normal fare. The way it works is that you pre-load it at one of the OMS reloading machines which can be found around the city at metro stations or you can load it at various newspaper stands. You only need to buy one card even if your traveling with a few people (up to 5 passengers), just as long as you load it with enough TL for everyone s ride and make sure to swipe it as each person goes through the turnstile. Metro + Funicular The Metro and Funicular in stanbul are clean, modern and efficient. Each ride on the metro is 1.50 TL with an option to ride on 2 metro lines, 5 tram lines and 2 funiculars. Using the metro you can get to most popular areas within the city, including Topkapisaray, Taksim, and the Ataturk Int Airport. Even if the metro doesn t stop exactly where you need it to, you re likely to be dropped off within a short walking distance. The funicular is particularly convenient to get to Kabatas because walking would involve a painfully steep climb up the hill. 11

12 Link Here are the different train lines Dolmus The Aksaray-Airport (Havaliman ) Metro Line (M1) The fiiflhane-atatürk Oto Sanayii Metro Line (M2) The Zeytinburnu-Kabatafl Tram Line (T1) The Taksim-Kabatafl Funicular (F1) Dolmuses are private minibuses that wait until all the seats are filled up before taking off. While the driver does have designated stops, if you want to get off somewhere else along the route, they can drop you off there too. Especially if you don t know the area or what the stop looks like, tell the driver ahead of time where you would like to be dropped off, because if no one says anything the driver will continue driving to the next stop. On a dolmus you cannot use the stanbul Kart and drivers prefer exact change, so be sure to carry small bills and coins. A dolmus ride can be anywhere from 3TL to 5TL, but make sure to ask the driver to clarify the cost. 12

13 Ferry (Vapur) You will love taking the ferry (or vapur in Turkish) because it is one of the best ways to see the city. In stanbul, the ferry is a very common mode of transportation and depending on where you are going can be the quickest way across the city. Ferries in stanbul cost between 1.5TL and 5 TL depending on the distance. You purchase a cup of tea or coffee and sip it with a beautiful view of the cityscape from the sea! Most ferry lines take off from Eminonu, which is walking distance to Topkapi Saray. Another popular ferry route in the summer/winter is to the Prince Islands, the most popular being Kinaliada, Buyukada and Burgazada. You can spent a majority free day on Kinaliada, we highly recommend the trip. Taxis Both airports in stanbul have taxi stations. When in the city you may contact your hotel reception to request one. There is only one tariff in use and an initial starting fee of 2.95 Turkish Liras and a charge 2.83 Turkish Liras per kilometer is applied in stanbul. Airport The easiest and quickest way to get to and from either Ataturk Airport or Sabiha Gokcen Airport in stanbul is by the Havatas airport bus. According to their website, The Havatas waiting area is in(european side, for Ataturk Airport) Taksim near the metro station, (Asian side, for Sabiha Gokcen Airport) Kad köy near the dock and bus stops making it convenient to get to the Havatas, but it s also easy to get to wherever you want to go if you have arrived with the Havatas from the airport. 13

14 Public airport shuttle buses (HAVATAS) run between the airport and the city center (Taksim Square) from 5.00 a.m. to p.m. every half hour. It takes about 40 min from airport to the city centre. Transportation within the city centre is by bus or by taxi. All taxis have taximeters, and the rates are reasonable. Taking a Havatas Public Bus to Taksim Square might be more recommendable for a trip to/from airport. The quickiest and comfortable way to cross Bosphorus, the water channel between Asia and Europe, could be considered as taking public boats which depart from Besiktas, Eminonu, Karakoy on the European Side and Kadikoy, Uskudar, Bostanci on the Asian Side. Please refer to the hotel concierge for more information while planning your trip within the city. One way transfer (from Sabiha Gökçen airport Hilton Kozyata hotel - airport) is 85.-Euro including VAT per person. The type of vehicles are bus & midibus. For private vehicle, please kindly contact with meeting organization secreteriat. Useful Telephone Ambulance : 112 Numbers Fire : 110 Police : 155 Country Code : 90 City Code For European section of the city : 212 For Asian section of the city :

15 Welcome Home Welcome Home The ancient churches, synagogues, the mosques, the mausoleums, the palaces the bazaars and the baths are standing today as the period of all civilizations lived on the land. The city which bridges two continents It seems to be that while other cities are mortal, this one will endure as long as there are men on the earth Pierre Gilles stanbul, which was known as the capital of the capital cities, and created huge peace geographies with reigning to first Roman, and then Eastern Roman (Byzantium) Empire and continents, and was the capital city of Ottoman Empire, is going to a modern future with preserving magnificence of history with proud. Variety in stanbul is really charming the visitors. It is serving infinite nuances with its museums, churches, palaces, mosques, bazaar places and natural beauties. 15

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