Chromosome Conference



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ANNOUNCING The Fiftieth Annual Great Lakes DATES: May 17-18, 2012 LOCATION: 89 Chestnut Street, University of Toronto ACCOMMODATION: Conference rates are not available at the Metropolitan Hotel or at the University of Toronto Residences. Please make your reservations early! The Metropolitan Hotel: University of Toronto Residences: 108 Chestnut Street, Toronto Telephone: 1 (800) 668-6600 or 1 (416) 599-0555 Room Rate: ~ $200.00 89 Chestnut Street, Toronto Telephone: 1 (416) 977-0707 press 0 Room Rate ~ $99.00 single or double plus taxes (basic accommodation no TV/no room service full breakfast buffet included) GLCC REGISTRATION FEES 1. Advance registration (by April 30, 2012) Regular: $120 (CDN or USD) Student: $70 (CDN or USD) 2. Late registration (After April 30, 2012) Regular: $150 (CDN or USD) Student: $100 (CDN or USD) One Day: $80 (CDN or USD) One Day: $40 (CDN or USD) One Day: $100 (CDN or USD) One Day: $70 (CDN or USD) PLEASE NOTE THAT PAYMENT MUST ACCOMPANY ALL REGISTRATIONS. IF PAYMENT IS NOT RECEIVED BY APRIL 30, THE LATE REGISTRATION FEE WILL APPLY AT THE DESK UPON CHECK-IN. A continental breakfast and lunch for both days of the meeting, as well as a wine and cheese after Thursday s sessions, are included in the registration fee. A Thursday evening social dinner is scheduled, but this is NOT included in the registration fee. Please budget ~ $80 (CDN) for this event.

Please mail cheque, payable to The Great Lakes, with your registration to: Ellen Mak-Tam, GLCC Registrar North York General Hospital Genetics Program 4001 Leslie St. 3SE Toronto, ON M2K 1E1 A receipt will be issued at the meeting. WE ARE SORRY WE CANNOT ACCEPT CREDIT CARDS HIGHLIGHTS OF THE 2012 GREAT LAKES CHROMOSOME CONFERENCE Here is a sampling of topics this year: Vincenzo Cirigliano, Head of Molecular Genetics, Labco Diagnostics, Barcelona, Spain Rapid Aneuploidy screening by QF-PCR and the changing scene in prenatal diagnosis Suzanne Kamel-Reid, Head, Laboratory Genetics, University Health Network, Toronto, Ontario Targeted mutation analysis in oncology: personalized medicine at work Josée Lavoie, Associate Director, Cytogenetics Laboratory, Montreal Children s Hospital, Montreal, Quebec Group presentation on interesting cases or lab-related problems Darrell Tompkins, Professor Emeritus of Medical Genetics, University of Alberta, Edmonton, Alberta The Roberts Syndrome Story, 1978-2008 Tanya Gillan, Clinical Cytogeneticist and Molecular Geneticist, Cytogenetics Laboratory, Vancouver General Hospital, Vancouver, British Columbia My cut-off is bigger than yours! Experience from the BC inter-laboratory FISH validation study Georges Maire, Cytogeneticist, Mount Sinai Hospital, Toronto, Ontario Genetics of dermatofibrosarcoma protuberans family of tumors: from ring chromosomes to tyrosine kinase inhibitor treatment

Judy Chernos, Director, Cytogenetics Laboratory, Genetic Laboratory Services, Alberta Children's Hospital, Alberta Health Services, Calgary, Alberta Array CGH Coming of Age in the Diagnostic Laboratory AnneMarie Block, Director, Clinical Cytogenetics Laboratory, Roswell Park Cancer Institute, Buffalo, New York The Role of FLT3 in Sole Trisomy 8 Acute Myeloid Leukemia Marsha Speevak, Laboratory Geneticist, Credit Valley Hospital, Mississauga, Ontario 50 th GLCC: historical perspective in pictures The H. Allen Gardner Memorial Lecturer: Dr. Janet Rowley, MD, Blum-Reise Distinguished Service Professor of Medicine, Molecular Genetics, Cell Biology and Human Genetics, University of Chicago The Philadelphia Chromosome Story

CALL FOR PAPERS SESSIONS The GLCC is divided into three sessions: Session I: Cancer Cytogenetics; Session II: Clinical Problems; Session III: New Technologies. The meeting closes with the annual Allen H. Gardner Memorial Lecture. The following guidelines are suggested: 1. Please email title/abstract to mary.shago@sickkids.ca or fax to: 416-813-4956 Attn: Dr. Mary Shago. Please include authors names and addresses and the email address of the presenting/corresponding author (underlined). The abstract should be limited in length to 250 words or less for publication to the web. 2. Titles and abstracts are accepted on a first come basis, until timeslots are filled. An email confirmation will be sent acknowledging receipt of the abstract. Presenters will be informed of the assigned timeslot approximately two weeks prior to the meeting. 3. Presentations should be no more than 20 minutes, which includes a 5-minute question and discussion period. 4. The following media are acceptable: PowerPoint presentations on CD or USB drive. A PC notebook will be available. Please note: 35 mm slides and overheads will not be accepted. 5. Early Submission Prizes: Abstracts received by April 30 will be eligible for 3 random draws of $100.00 CDN each to be held at the meeting. 6. We are a friendly, receptive crowd, so you have nothing to lose by participating. We rely on you to make the meeting a success! So please select your cases now. RULES FOR EARLY SUBMISSION PRIZE 1. Abstracts/titles must be received by the advance registration deadline, April 30, in order to be included for the draw. Everyone is eligible except meeting organizers. 2. A random draw of the titles from each session will be performed and a cash prize awarded to each presenter that is drawn.

DECLARATION OF POTENTIAL CONFLICT OF INTEREST Please note, as required by the Faculty of Medicine, University of Toronto, all speakers will be requested to disclose to the audience, any real or apparent conflict of interest that may have a direct bearing on the subject matter of this program. Please include a PowerPoint slide (second slide after the title/topic slide) declaring any apparent conflicts(s) of interest that may have a direct bearing on the subject matter of this program. INFORMATION We look forward to your suggestions and to seeing you in May. For more information please feel free to call Dr. Kathy Chun at (416) 756-6438; Fax # (416) 756-4729; email kathy.chun@nygh.on.ca.

PRELIMINARY PROGRAM All events to be held on the 2 nd floor, at University of Toronto, 89 Chestnut Thursday, May 17 0815-0845 Registration and morning wake-up (coffee, muffins) Centre Room, 2 nd Floor 0845-0900 Introductory Remarks Session I: Cancer Cytogenetics Chair: AnneMarie Block 0900-0920 The Role of FLT3 in Sole Trisomy 8 Acute Myeloid Leukemia AnneMarie Block (Roswell Park Cancer Institute, Buffalo, NY) 0920-0940 Genetics of dermatofibrosarcoma protuberans family of tumors: from ring chromosomes to tyrosine kinase inhibitor treatment Georges Maire (Mount Sinai Hospital, Toronto, ON) 0940-1020 Short Presentations 1020-1050 Break 1050-1200 Short Presentations 1200-1330 Lunch Provided Session II: Clinical Problems Chair: Tanya Gillan 1330-1350 My cut-off is bigger than yours! Experience from the BC interlaboratory FISH validation study Tanya Gillan (Vancouver General Hospital, Vancouver, BC) 1350-1450 Group presentation on interesting cases or lab-related problems Josée Lavoie (Montreal Children s Hospital, Montreal, QC) 1450-1520 Break 1520-1600 The Roberts Syndrome Story, 1978-2008 Darrell Tompkins (Professor Emeritus, University of Alberta, Edmonton, AB)

1600-1700 Short Presentations 1700-1800 Wine & Cheese Reception Terrace (3 rd Floor) Friday, May 18 0830-0900 Registration and morning wake up Centre Room, 2 nd Floor Session III: New Technologies Chair: Judy Chernos 0900-0920 Array CGH Coming of Age in the Diagnostic Laboratory Judy Chernos (Alberta Children s Hospital, Calgary, AB) 0920-0950 Targeted mutation analysis in oncology: personalized medicine at work Suzanne Kamel-Reid (University Health Network, Toronto, ON) 0950-1030 Short Presentations 1030-1100 Break 1100-1140 Rapid Aneuploidy screening by QF-PCR and the changing scene in prenatal diagnosis Vincenzo Cirigliano (General Lab, Barcelona, Spain) 1140-1200 Short Presentation 1200-1330 Lunch Provided 1330-1345 50 th GLCC: historical perspective in pictures Marsha Speevak (Credit Valley Hospital, Mississauga, ON) 1345-1445 H. Allen Gardner Memorial Lecture: The Philadelphia Chromosome Story Dr. Janet Rowley (University of Chicago, Chicago, Il) 1445-1500 Conclusion and Adjournment of GLCC