SÁNCHEZ MARGALLO, Francisco Miguel

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SÁNCHEZ MARGALLO, Francisco Miguel Dr. Sánchez is the Scientific Director at the Jesús Usón Minimally Invasive Surgery Centre (JUMISC) located in Cáceres, Spain. The JUMISC is a multidisciplinary institution delivering excellence in research and training of minimally invasive surgical techniques. It promotes technological development and innovation applied to medicine and health, in close collaboration with companies around the world. Project Manager for minimally invasive techniques with particular responsibility regarding biomaterials, medical devices, new techniques, preclinical trials and imaging diagnosis in laparoscopic, endoscopic and other minimally invasive procedures and surgical technologies. EDUCATION and TRAINING DR. SÁNCHEZ MARGALLO 1992 University of Extremadura. Degree in Veterinary Medicine. 1992 Univ. Extremadura. Chair of Surgery. Resident. 1994 University of Extremadura. FPI Scholarship. Chair of Surgery. 1999 University of Extremadura. PhD. (National Prize 2001) 1999 Official College of Technical Architects and Surveyors (Málaga). Master s Degree in Consultancy and Environmental Verification. 2000 East Carolina University. Postgraduate stay in the Telemedicine Center of the Brody School of Medicine. North Carolina University. USA. PROFESSIONAL CERTIFICATIONS 1992-1997 Minimally Invasive Surgery Centre. Coordinator of the Endoscopy Unit. 1997-2007 Minimally Invasive Surgery Centre. Director of the Surgical Area and Coordinator of the Laparoscopy Unit. 2000- Director of the Quality Assurance System (ISO 9001:2008) 2007- Director of the Contract Research Organization CRO- (under GLP certification) for preclinical trials 2014- Director of the Centre attached to the University of Extremadura (Fundación Centro de Cirugía de Minima Invasión Jesús Usón) 2014- Director of the Large Singular Spanish Scientific and Technological Infrastructure (ICTS- Nanbiosis-) CURRENT RESEARCH PROJECTS New approaches for MIS: NOTES and Laparoendoscopic Single-site Surgery (LESS) New devices for Minimally Invasive Surgery Minimally Invasive Surgical pedagogical model based on video Technology Enhanced Learning Online vocational Training on laparoscopy's ergonomics for

DR. SÁNCHEZ MARGALLO surgeons and laparoscopic instruments' designers. Testing validation of innovative surgical training concepts New osteoinductive biomaterials for bone regeneration Evaluation of bioactive dressing for treating skin ulcers Immunomodulatory Role of Exoxomes Secreted From hascs: An in vitro Analysis Development of new technologies to improve embryo implantation in IVF Physicochemical characterization in vivo of the oviductal environment by minimally invasive approaches Cardiovascular research (stem cell therapy and MIS in cardiovascular diseases) System for improving the diagnosis and monitoring of neuropathic pain in patients with spinal cord injury: biometric records, questionnaires of pain and validation techniques e-learning serious game for surgical skills training MIS in uterine transplantation Participation in more than 80 research projects financed by public and private entities. TRAINING and EDUCATION ACTIVITIES Director and lecturer of more than 600 Hands-on Courses on Minimally Invasive Techniques (/training) Director of certified EAES Courses on Laparoscopic Colorectal Surgery and Laparoscopic ERGE Surgery. Director of University Specialist Courses on Minimally Invasive Surgery (University of Extremadura) Lecturer of Universitary Masters (Universidad Complutense of Madrid-Gynecology and Bioengineering-, Universidad of Murcia-Reproduction-). Director of the Centre attached to the University of Extremadura (Fundación Centro de Cirugía de Minima Invasión Jesús Usón) PUBLICATIONS Author of 103 scientific articles published in journals with Impact Factor, and author of 148 articles related to Minimally Invasive Surgery. (h index: 14)(References: 797) Author and co-author of 15 books, author and co-author of 47 chapters of books. Author and co-author of 19 copyrights. Author of 10 Utility Models, 8 Patents and 18 Community Industrial Designs. Author of more than 220 scientific posters, more than 400 invited communications and free communications presented at National and International Congresses, 83 scientific videos

and 13 interactive CD and DVD. Author of 3 app related to Minimally Invasive Surgery and Health (for IOS and Android) (store.ccmijesususon.com) MEMBERSHIPS and AFFILIATIONS DR. SÁNCHEZ MARGALLO Member of numerous International Scientific Committees such as the First Medical Engineering Meeting, I Simposium of Cell Theraphy and Renegerative Medicine, I Iberian International Course on Laparoscopic and Thoracoscopic Surgery, Conference of the Society for Medical Innovation and Technology (SMIT) 2012, 3rd International Symposium on Minimally Invasive Surgery in Veterinary and MEDICON 2013. Member of the National Scientific Committee of the 1 st, 2 nd and 3 rd Symposiums on Training Upgrading in Laparoscopic and Robotic surgery, across a multidisciplinary scope SECLA 2012-2013-2014. Member of CEBA (Spanish National Animal Welfare and Ethics Committee) at the JUMISC. Member of the Expert Committee of the Health Plan for Extremadura. Regional Autonomous Government of Extremadura. Lecturer on Official Universitary Masters on Biology and Technology of the Reproduction of Murcia University, on Endoscopic Gyneacology Surgery of the Autonomous University of Madrid and on Telemedicine and Bioengineering of the Polytechnics University of Madrid. Director of the Master on Podology Surgery of the University of Seville. Member of the Honor Committee of the VII National Congress on Informatics and Pharmacy and the XVIII National Congress of Blood Donors. Honorary Member of the Sociedade Portuguesa de Cirurgia Minimamente Invasiva (2008). Full Membership of the Society for Medical Innovation and Technology (SMIT), of the European Association for Endoscopic Surgery and other interventional techniques (EAES), of the Spanish Urology Association (AEU) Spanish Society of Surgeons (AEC), Spqanish Society of Surgical Research (SEIQ) and of the Spanish Society of Laparoscopic and Robotic Surgery (SECLA). Member of the Board of Directors of the Spanish Association for Surgical Research (SEIQ). Member of the Technological Committee of the European Association of Endoscopic Surgeons (EAES).

AWARDS AND HONORS 28 national and international prizes related to research. Prize of the Royal Academy of Spanish Doctors (2001). President of the Organizing Committee of the XXIX Annual Congress of the Spanish Society of Biomedical Engineering. CASEIB2011. Reviewer for scientific international journals: o Open Access Surgery Journal o Research in Veterinary Science o Journal of Minimal Access Surgery o Catheterization and Cardiovascular Interventions o American Journal of Veterinary Research o Archives of Clinical and Experimental Surgery (ACES) o Surgical Endoscopy o PLOS ONE o Hindawi Publishing Corporation o Contrast Media and Molecular Imaging o Journal of the American Veterinary Medical Association (JAVMA). Reviewer for International Conferences: the International Conference on Information and Communication Technologies and Applications and the International Conference on Complexity, Cybernetics, and Informing Science and Engineering. Member of the International Advisory Board of ScopeMed and of the Editorial Board of ISRN Minimally Invasive Surgery, Science and Education Publishing (SciEP), Edorium Journal of Robotic Surgery and of Archives of Clinical and Experimental Surgery. Contributor to Research Networks and Platforms: o Cross-border network Extremadura Centro Alentejo (RITECA) o Managing bodies of Hospital and Biosanitary Clinical Research spanish network (REGIC) o Plataform of Biotechnological Markets o European and Spanish Plataform on Biomedical and Nanomedicine Research (NANOTECHNOLOGY & NANOMED) o Spanish Technological Plataforms for Animal Healthcare (Vet+i), for Integrated Intelligence Systems (PROMETEO-ARTEMIS) and robotics (HISPAROB) o Platform ITEMAS, for Innovation on Healtcare and Medical Innovation of the ISCIII o Cardiovascular Network(RIC)

o Centre for Biomedical Cooperative Research: Bioengineering, Biomaterials and Nanomedicine (CIBER BBN) o Spanish Technological Plataform on Advanced Materials and Nanomaterials (MATERPLAT). POSTGRADUATE COURSES AND THESIS Director of 18 Doctoral Thesis and 398 postgraduate courses. University Expert tutor and Director of 6 Master s Degrees.