Roche Position on Human Stem Cells
|
|
- Bruce Glenn
- 8 years ago
- Views:
Transcription
1 Roche Position on Human Stem Cells Background Stem cells and treating diseases. Stem cells and their applications offer an enormous potential for the treatment and even the cure of diseases, along with enhancing and extending the quality of life. Roche is highly interested in scientific developments in stem cell research and its related applications both as a discovery tool and as a potential therapeutic modality. Roche is also fully aware of the important societal and ethical questions raised with regard to stem cell research and its potential applications. As in all our activities, we follow applicable law and we are open to dialogue with all stakeholders surrounding this area of research. About stem cells. Stem cells are particular cells that have the unique capability to renew themselves and to give rise to all specialized cell types such as heart cells or blood cells. Stem cells can be classified as follows: Adult stem cells are derived from tissues like bone marrow or cord blood. They are already successfully used for the treatment of patients with e.g. leukemia. The treatment of further diseases with adult stem cells is currently under evaluation. However, those cells only develop into a limited number of cell types. Hence the need remains for concomitant research with embryonic stem cells for specific applications. Embryonic stem cells are isolated from embryos. These cells are pluripotent, which means that they can develop into any fetal or adult cell type (blood, heart, brain cells, etc.), but they cannot develop into a complete organism. Induced pluripotent stem cells (ips) are derived from adult cells, such as skin cells, and are being re-programmed to a pluripotent stage: once re-programmed, they exhibit similar properties as embryonic stem cells. If ips cell technology develops as expected, it may eventually replace the need to derive stem cells from embryos. Stakeholders Concerns and Expectations 1
2 Expectations and hopes within this area of research are high: stem cells and their applications may eventually enable researchers to find successful treatments for severe diseases for which we can offer few, if any, effective therapies today. Diseases or indications often mentioned in this context include Alzheimer s, multiple sclerosis, paraplegia, diabetes, Parkinson s and heart failure. Ethical considerations on the use of stem cells vary widely and depend, to some extent, on an individual s cultural and religious background. The discussion centres on the following topics: The use of blastocysts (a blastocyst is a human embryo in a very early, preimplantation stage of development from which embryonic stem cells can be isolated). Whether human embryonic stem cells should be used for research and/or as potential treatments for various diseases. Whether and how society should accommodate these diverse views in regulating the use of stem cells, with due consideration of the effect of such regulation on freedom of research and benefit for patients. Roche s Position Stem cell research is necessary. Worldwide progress in stem cell research over the past years has shown that scientific developments in pluripotent stem cell biology (i.e. the reprogramming of adult stem cells or somatic cells into pluripotent ones) provides a promising opportunity for the future and Roche is also engaged in using these technologies. However, the scientific understanding of these technologies is still at an early stage. Therefore, parallel research using both adult and embryonic stem cells is necessary to increase the understanding of diseases and develop treatments. Roche conducts stem cell research, in-house as well as in cooperation with external partners, to become technically enabled in this research area, and with the ultimate aim to develop treatment strategies for incurable or inadequately treated severe diseases. Roche is aware of the ethical concerns related to stem cell research. However, we believe that the vast potential and hope that stem cells might bring to patients to treat, prevent or diagnose a disease justifies this research, provided it is done responsibly, in compliance with laws and regulations, in dialogue with stakeholders, and with the ultimate aim of 2
3 developing new and more effective therapies for diseases that can currently not, or only partly, be treated. Principles for using Human Stem Cells in research. Roche is committed to a responsible and transparent approach to stem cell research. For this reason, clear principles for the Use of Human Stem Cells in research have been developed. The following principles apply to all research projects involving human stem cells, which Roche undertakes. They include: projects using stem cell research as a discovery tool projects looking into potential therapeutic modalities. All Roche employees involved in human stem cell research are subject to these principles, which are designed to be applicable worldwide, subject to national laws and regulations. General Principles for Human Stem Cells for Research Principles 1-7 apply to research on all human stem cells. 1) The ultimate aim of Roche s research using stem cells is to increase the understanding of serious diseases and to develop effective diagnostic tools and treatments. 2) Each research project must have clear scientific objectives and design, in particular in accordance with good clinical practice. 3) Prior written, voluntary informed consent of the donor 1 of the genetic material 2 must be obtained before human stem cell research is carried out. 4) Roche will not offer any inducements, financial or otherwise, to donors. 5) Roche will comply with all applicable national laws and regulations on stem cell research, which may differ from country to country. 6) Roche is committed to an open dialogue with stakeholders in this area of research. 1 The term donor is generally understood as an individual who donates biological material, and, in the case of human embryo donation (in jurisdictions where applicable), the individual or couple for whose reproductive use embryos were created. 2 Examples of genetic material: tissue, gametes (=eggs or sperm), embryos. 3
4 7) Roche will proactively encourage all its external contractors, who perform stem cell research for Roche, to abide by the same principles and conduct their research with the same high standards as Roche. In addition to principles 1-7, principles 8-10 apply to research on human embryonic stem cells. 8) Roche intends to move increasingly toward using technologies such as induced Pluripotent Stem Cells (ipscs) that could one day replace the need to derive stem cells from embryos. Until such technologies are fully developed, parallel research using both embryonic stem cells and ipscs will remain necessary. 9) In the case of stem cell lines derived from embryos, Roche uses only embryos that have been created through in vitro fertilisation for reproductive purposes, that are no longer needed for those purposes, and that have been donated for research (with voluntary and informed consent). 10) Roche will not engage in human reproductive cloning. Current engagement, initiatives and guidelines Examples of Roche s current engagement, initiatives and guidelines can be found in Appendix 1. Outlook The Roche Science and Ethics Advisory Group (SEAG) offers advice and counsel on a broad range of ethical matters. It is a panel made up of independent external experts in bioethics and philosophy, and provides consultative feedback on ethical approaches to biomedical and clinical research, in particular on topics that are perceived as particularly sensitive or controversial by the public at large in order to take into account as many perspectives as possible. SEAG has also provided feedback to this Position Paper. This updated position paper was proposed by the Corporate Sustainability Committee and adopted by the Corporate Executive Committee on 13 May, 2013 and entered into force the same day. It replaces the version from May 12, 2009 and was reviewed in May
5 Appendix 1 Current engagement, initiatives and guidelines Roche Principles for Use of Human Stem Cells In 2011, Roche adopted principles governing the use of human stem cells for research, which have been developed in consultation with the Roche SEAG. They apply to all research projects involving human stem cells that Roche or its contractors undertake. Roche s in-house activities Roche s in-house stem cell research includes the use of human stem cells both as a discovery tool and as a potential therapeutic modality. Roche is developing expertise to become technically enabled in this research area and to conduct research on human stem cells and their use in drug discovery. The aim is to develop treatment strategies for incurable or inadequately treated severe diseases, for example, Central Nervous System disorders. Roche has also started research and pre-clinical feasibility projects on the use of adult stem cells also in devastating diseases. Roche s external collaborations Roche provides our external partners with compounds from our drug library for toxicological and safety tests and screening in various human stem cell lines in an effort to improve drug development whilst reducing animal testing and potential Serious Adverse Events in human trials. Massachusetts General Hospital (Boston, USA) and Harvard University (Cambridge, USA). In 2010, Roche commenced a three-to-five year joint research collaboration with Massachusetts General Hospital (Boston, USA) and Harvard University (Cambridge, USA). In this collaboration stem cell technologies are used to advance drug discovery in areas of high unmet medical need with an initial focus on metabolic disorders and cardiovascular disease. The aim is to develop cellular models of diseases based on human stem cell lines and to investigate the potential efficacy, safety and toxicology profile of new drug candidates 5
6 from Roche s compound library. Cell lines will be derived from the tissues of healthy volunteers and from patients with various diseases. In January 2012, Roche entered a research and development agreement together with the Harvard Stem Cell Institute, Harvard Medical School, and Children s Hospital Boston, to create in-vitro drug screening assays for the modelling of autism spectrum disorder (ASD) with the ultimate aim is to screen and identify new drugs for the treatment of the condition. In this unique partnership, skin biopsies from suitable individuals, after genetic screening of patients with specific genetic conditions causing ASDs, will be provided for fibroblast isolation and reprogramming into induced pluripotent stem cells (ipscs). These stem cells will be differentiated into lines of functional neurons that will be used to identify potential therapeutic targets and for a variety of drug screening assays. UK Stem Cell Consortium (SC4SM -Stem Cells 4 Safer Medicines). The objective of this consortium is to create a repository of stem cells suitable for toxicology testing in high-throughput platforms. The initiative is mainly supported by the UK government with Roche and two other pharmaceutical companies contributing. Activities are coordinated by a Board of Directors and a Scientific Advisory Board. Roche is represented on the steering bodies of this initiative and funded this initiative for the pilot phase. UCLA. In June 2011, Roche entered into a collaboration agreement with UCLA to access its technologies to support the research conducted by the Eli and Edythe Borad Center of Regenerative Medicine and Stem Cell Research and UCLA's Jonsson Comprehensive Cancer Center. Roche will provide UCLA with advanced reagents, technologies and bioinformatics support to further understand complex diseases and discover new predictive biomarkers that will be used as targets for future therapeutics. University Medical Center Utrecht in Netherlands/Bioscience Department of AstraZeneca R&D. In February 2012, Roche's xcelligence Cardio Instrument was used to detect beating rhythm and proarrhythmic effect of drug compounds in cardiomyocytes, obtained by differentiating human induced pluripotent stem cells (hipsc) or mouse embryonic stem cells (mesc). The study was conducted by scientists from the University Medical Center Utrecht in Netherlands and the Bioscience Department of AstraZeneca R&D in Sweden. According to the company's website, Roche's xcelligence Cardio systems can be used in combination with stem cell-derived cardiomyocytes as an assay system to support screening of compound toxicity and risk 6
7 assessment. The system can be used to directly measure drug effect on beating of cardiomyocytes derived from mescs, hipsc, and human embryonic stem cells. Comprehensive Pulmonary Center, Helmholtz Association, Munich, Germany. Since October 2010, Roche supports a research group of the Comprehensive Pneumology Center (CPC) and the institute of Lung Biology and Disease (ilbd) with its department of pharmaceutical research. The group will do research on new cell therapy methods with adult mesenchymal stromal-type cells for chronic lung diseases such as idiopathic lung fibrosis (IPF), diseases with a high unmet medical need. Lung fibrosis leads amongst other symptoms to considerable breathing troubles contributing to a severe loss of quality of life and has a poor prognosis of only a few years life expectancy after diagnosis. 7
Guidance For Research Involving Human Embryonic Stem Cells, Germ Cells, And Cells Obtained From Cord Blood
Guidance For Research Involving Human Embryonic Stem Cells, Germ Cells, And Cells Obtained From Cord Blood Supreme Council of Health Department of Research Guidance Regarding Research Involving Human Embryonic
More informationBackground Information
Background Information 1. What are stem cells? 2. What might stem cell research achieve? 3. Why we need to continue research using embryonic stem cells? 4. Time taken for discoveries 5. Examples of stem
More informationWhat are Stem Cells? How can they be used in medicine?
What are Stem Cells? How can they be used in medicine? What is a stem cell????... What is a stem cell????......a cell with the ability to differentiate into specialized cells and renew to become more stem
More informationStem Cell Quick Guide: Stem Cell Basics
Stem Cell Quick Guide: Stem Cell Basics What is a Stem Cell? Stem cells are the starting point from which the rest of the body grows. The adult human body is made up of hundreds of millions of different
More informationHuman stem cell research: a novel technology that will benefit patients Information and Position Paper
October 2003 Human stem cell research: a novel technology that will benefit patients Information and Position Paper EuropaBio, the European Association for Bio-industries, has 35 corporate members operating
More informationSTEM CELL FACTS. The ISSCR is an independent, nonproft organization providing a global forum for stem cell research and regenerative medicine.
STEM CELL FACTS The ISSCR is an independent, nonproft organization providing a global forum for stem cell research and regenerative medicine. WHAT ARE STEM CELLS? Stem cells are the foundation cells for
More information15 Stem Cell Research
15 Stem Cell Research t a l k it o v e r 1 c l a s s se s s i o n Overview Students read about current scientific research on and the social controversy over embryonic stem cells. On a KWL literacy strategy
More informationguides BIOLOGY OF AGING STEM CELLS An introduction to aging science brought to you by the American Federation for Aging Research
infoaging guides BIOLOGY OF AGING STEM CELLS An introduction to aging science brought to you by the American Federation for Aging Research WHAT ARE STEM CELLS? Stem cells are cells that, in cell cultures
More informationBriefing on the second reading of the Human Fertilisation and Embryology Bill, Monday 19 November 2007.
Briefing on the second reading of the Human Fertilisation and Embryology Bill, Monday 19 November 2007. Prepared by the Medical Research Council, Royal Society and Wellcome Trust The Medical Research Council,
More informationStem Cells and Inner Ear Cell Regeneration. Stefan Heller Stanford University School of Medicine
Stem Cells and Inner Ear Cell Regeneration Stefan Heller Stanford University School of Medicine Embryonic stem cells Induced pluripotent stem cells Somatic stem cells 50 µm Derived from the inner cell
More information5 Frequently Asked Questions About Adult Stem Cell Research
5 Frequently Asked Questions About Adult Stem Cell Research Stem cells are often referred to in the sociopolitical realm with some level of controversy and beyond that, some level of confusion. Many researchers
More informationStem Cells and Hope for Patients
Stem Cells and Hope for Patients by Maureen Condic, Ph.D. Most Americans know someone afflicted with an incurable medical condition. The possibility of stem cell cures has given hope to many who face such
More informationStem cells and motor neurone disease
Stem cells and motor neurone disease F Stem cell research has fuelled hope of a treatment for a variety of conditions. This information sheet explains what these cells are and includes details of the current
More informationStem Cell Research: Adult or Somatic Stem Cells
Chiang 1 Stem Cell Research: Adult or Somatic Stem Cells Abstract Kelly Chiang Cluster 7 Dr. LeFebvre 07/26/10 Over the past few decades, stem cells have been a controversial topic in the scientific field.
More informationPART I. SECTION 1. The legislature finds that an estimated. 128,000,000 Americans suffer from the crippling economic and
HOUSE OF REPRESENTATIVES TWENTY-FOURTH LEGISLATURE, 2007 STATE OF HAWAII A BILL FOR AN ACT RELATING TO MEDICAL RESEARCH. BE IT ENACTED BY THE LEGISLATURE OF THE STATE OF HAWAII: PART I SECTION 1. The legislature
More informationDifferentiation = Making specialized cells
Differentiation = Making specialized cells What is a stem cell? Screws: JM www.logodesignweb.com/stockphoto Differentiation = Making specialized cells What is a stem cell? What the photo shows A lump of
More informationStem cell research ACADEMY STATEMENT. progress, hopes and concerns ACADEMY STATEMENT 16 JANUARY 2013
ACADEMY STATEMENT 16 JANUARY 2013 ACADEMY STATEMENT Stem cell research progress, hopes and concerns KUNGL. VETENSKAPSAKADEMIEN, BOX 50005, SE-104 05 STOCKHOLM, SWEDEN TEL +46 8 673 95 00, FAX +46 8 15
More informationStem cells and motor neurone disease
Stem cells and motor neurone disease F Stem cell research has fuelled hope of a treatment for a variety of conditions. This information sheet explains what these cells are and how they may be used to create
More informationPolicy statement. Stem cell research
Policy statement Stem cell research Introduction For some people who survive a heart attack, the damage to their heart muscle can lead to debilitating heart failure, for which there is no cure. Nearly
More informationTHE PROMISE OF STEM CELL RESEARCH
THE PROMISE OF STEM CELL RESEARCH MALIGNANT OSTEOPETROSIS AUTOSOMAL RECESSIVE DENSE SCLEROTIC SKELETON HEMATOLOGIC ABNORMALITIES NEUROLOGIC ABNOMALITIES DEATH IN INFANCY OR EARLY CHILDHOOD SUCCESS RATE
More informationThe ethics of stem cell research and treatment
The ethics of stem cell research and treatment Bernard Lo, M.D. March 12, 2009 1 hesc: ethical controversies Moral status of embryo? Clearly a potential person Some believe a person with rights Is hesc
More informationtem ells /background /information Stem cell research Copyright 2007 MRC Centre for Regenerative Medicine, Institute for Stem Cell Research
tem ells /background /information Stem cell research Copyright 2007 MRC Centre for Regenerative Medicine, Institute for Stem Cell Research /02 /information Table of contents Page 01. What are stem cells?
More information34 Stem Cell Research and Applications: Monitoring the Frontiers of Biomedical Research
34 Stem Cell Research and Applications: Monitoring the Frontiers of Biomedical Research Audrey R. Chapman, Mark S. Frankel and Michele S. Garfinkel In the face of extraordinary advances in the prevention,
More informationDebate Motion. This house proposes that the procurement and use of embryonic stem cells for scientific research is unethical. Stem Cell Research
Stem Cell Research Debate Motion Stem Cell Research This house proposes that the procurement and use of embryonic stem cells for scientific research is unethical. The dominant view in the scientific community
More informationChapter 16 Reproductive Technology, Gene Therapy, and Stem Cells (modified)
Chapter 16 Reproductive Technology, Gene Therapy, and Stem Cells (modified) Assisted Reproductive Technologies (ART) Artificial insemination (AI) In vitro fertilization (IVF) Gamete intrafallopian transfer
More informationPatient Handbook on Stem Cell Therapies
Patient Handbook on Stem Cell Therapies Appendix I of the Guidelines for the Clinical Translation of Stem Cells www.isscr.org 2008, International Society for Stem Cell Research 2 Introduction We have all
More informationStem Cell Research. Debate motion
Stem Cell Research Debate motion This house proposes that the potential benefits of using embryonic stem cells to develop new medical treatments mean we have a moral obligation to support this type of
More informationThe Types of stem cells: Totipotent Pluripotent Multipotent
Stem Cells is the main material for building and regeneration of the body Stem cells are not differentiated and can transform to any cell of organism Stem cells are capable of indefinite renewal through
More informationSupport structure for genetic material
Support structure for genetic material 1 Making proteins in the RER Making copies of humans 2 Making copies of cells Making copies of genetic material 3 Making copies of genetic material Making copies
More informationElena Bryzgalina. Bioethical and Legal Regulation of the Use of Stem Cells and Stem Cell Technologies in Modern Russia
Bioethical and Legal Regulation of the Use of Stem Cells and Stem Cell Technologies in Modern Russia Elena Bryzgalina PhD, Member of the committee on bioethics of the Lomonosov s Moscow State University,
More informationPlease visit this site for the current GESCR procedures info: http://www.research.ucsf.edu/chr/stemcell/scprocedures.asp
GESCR PROCEDURES: REVIEW PROCESS AND LEVELS OF REVIEW Office of Origin: Human Research Protection Program Effective Date: January 2012 I. Introduction The Human Gamete, Embryo and Stem Cell Research (GESCR)
More informationAn Introduction to Stem Cells
By Kirstin Matthews, Ph.D. An Introduction to Stem Cells Overview Stem cells are cells that have the potential to replicate themselves for indefinite periods and to divide, producing one of themselves
More informationSTEM CELL FELLOWSHIP
Module I: The Basic Principles of Stem Cells 1. Basics of Stem Cells a. Understanding the development of embryonic stem cells i. Embryonic stem cells ii. Embryonic germ cells iii. Differentiated stem cell
More informationCONSENT FORM TEMPLATE. Derivation and Distribution of Induced Pluripotent Stem (ips) Cell Lines Created from Donor Specimens
CONSENT FORM TEMPLATE Derivation and Distribution of Induced Pluripotent Stem (ips) Cell Lines Created from Donor Specimens INTRODUCTION We invite you to take part in a research study at [name of research
More informationHow To Treat Leukaemia With Cord Blood Stem Cell
Cord blood for the treatment of acute lymphoblastic leukemia in young children By Caitlin McGreevy Kiara Paramjothy Pass with Merit RESEARCH PAPER BASED ON PATHOLOGY LECTURES AT MEDLINK 2011 1 Abstract:
More informationStem cell research and Parkinson's
Parkinson's research Stem cell research and Parkinson's T his information sheet looks at what stem cells are and why they are important for research into a cure for Parkinson s. It also discusses where
More informationStem cells possess 2 main characteristics: Sources of pluripotent stem cells: -Long-term self renewal. -The inner cell mass of the blastocyst.
Stem cells possess 2 main characteristics: -Long-term self renewal. - They give rise to all types of differentiate cells. Sources of pluripotent stem cells: -The inner cell mass of the blastocyst. - Fetal
More informationInternational Stem Cell Registry
International Stem Cell Registry Importance of Stem Cells Stem cells are model systems for the study of development and disease. Pluripotent stem cells offer new tools for drug design and discovery. Pluripotent
More informationNew Issues in Stem cells and Regenerative Medicine
New Issues in Stem cells and Regenerative Medicine Bioethics and Biological Sciences Working Group Conference of European Churches Church and Society Commission 8, rue du Fossé des Treize, FR - 67000 Strasbourg,
More informationyour complete stem cell bank
your complete stem cell bank HYDERABAD - 88985 000 888, WARANGAL - 8297 256 777 VISAKHAPATNAM - 7799 990 774 VIJAYAWADA AND GUNTUR - 7799 990 771 NELLORE - 7799 990 772, KADAPA - 8297 256 700 RAJAHMUNDRY
More informationStem Cells: Scientific Progress and Future Research Directions
2001 Terese Winslow Stem Cells: Scientific Progress and Future Research Directions STEM CELLS: SCIENTIFIC PROGRESS AND FUTURE RESEARCH DIRECTIONS June 2001 This page intentionally left blank TABLE OF CONTENTS
More informationAct of 5 December 2003 No. 100 relating to the application of biotechnology in human medicine, etc
Act of 5 December 2003 No. 100 relating to the application of biotechnology in human medicine, etc Cf. earlier Acts of 5 August 1994 No. 56 and 12 June 1987 No. 68 Chapter 1. Purpose and scope 1-1. Purpose
More informationIt s not something you want to think about, but it s something you want to prepare for.
It s not something you want to think about, but it s something you want to prepare for. StemCyte cord blood banking offers your family a new lifesaving treatment alternative Why Bank Take the once-in-alifetime
More informationBrochure More information from http://www.researchandmarkets.com/reports/2860999/
Brochure More information from http://www.researchandmarkets.com/reports/2860999/ Stem Cells: Worldwide Markets for Transplantation and Cord Blood Banking (Projections for Stem Cell Use in Cancer, Alzheimer
More informationShould Stem Cells Be Used To Treat Human Diseases?
SAMPLE ESSAY C Should Stem Cells Be Used To Treat Human Diseases? Stem cells can be defined as undifferentiated cells that are generated during the development of the embryo. There are two functions ascribed
More informationSTEM CELLS FROM THE UMBLICAL CORD BLOOD AND UMBLICAL CORD TISSUE
STEM CELLS FROM THE UMBLICAL CORD BLOOD AND UMBLICAL CORD TISSUE What are Stem Cells? Stem cells are the basic building blocks of all the cells, tissues and organs in the human body. The role of the stem
More informationCONSULTATION RESPONSE
CONSULTATION RESPONSE Department for Business, Innovation and Skills (BIS): Regenerative Medicine Call for Evidence Response by the Wellcome Trust Introduction 1. The Wellcome Trust is pleased to have
More informationBiobanking Pluripotent Stem Cell Lines: UK and EU regulations Glyn Stacey, UK Stem Cell Bank, NIBSC
Biobanking Pluripotent Stem Cell Lines: UK and EU regulations Glyn Stacey, UK Stem Cell Bank, NIBSC ISCT Conference, New Zealand, April 2013 April 1 st 2013 NIBSC will become part of the Medicines and
More informationHow To Support Umbilical Cord Blood Stem Cell Research
Cauley O. Gieb Advanced Health Law HLP Article Umbilical Cord Blood Stem Cell Research: The Proof is in the Cord Today advances in science seem to gain the most recognition and support when the subject
More information4. All cord blood banks should be subject to the same standards, regulations and accreditation requirements.
WMDA Policy Statement on the Utility of Autologous or Family Cord Blood Unit Storage The WMDA Board adopted this policy on 25 th of May 2006. Policy updated _April 2011 The Cord Blood Working Group and
More informationEBiSC the first European bank for induced pluripotent stem cells
Press Release EBiSC the first European bank for induced pluripotent stem cells Pharmaceutical companies who are members of the European Federation of Pharmaceutical Industries and Associations (EFPIA)
More informationIntroducing stem cells Stem cells in the news
Introducing stem cells Stem cells in the news Stem cells: Therapeutic Value 16+ year olds February 2010, updated 2012 Objective: Understand the therapeutic value of stem cells About tissue stem cells Stem
More informationRESEARCH PAPER BASED ON PATHOLOGY LECTURES AT MEDLINK 2014
THE DEVELOPMENT OF STEM CELL RESEARCH AND TREATMENTS WITHIN MEDICINE BY JENNA BUXTON Grade awarded: Pass with Merit RESEARCH PAPER BASED ON PATHOLOGY LECTURES AT MEDLINK 2014 ABSTRACT This paper discusses
More informationThe Prospect of Stem Cell Therapy in Multiple Sclerosis. Multiple sclerosis is a multifocal inflammatory disease of the central
The Prospect of Stem Cell Therapy in Multiple Sclerosis Multiple sclerosis is a multifocal inflammatory disease of the central nervous system that generally affects young individuals, causing paralysis
More informationGenetics, Ethics &Meaning. Module 4
Genetics, Ethics &Meaning INItiative (GEMINI) Life Sciences and Society @University of Michigan Module 4 Myths versus Facts The University of Michigan s Stem Cell Research Environment A Case Study MYTH:
More informationDifferentiation = Making specialized cells. Your body needs stem cells. What is a stem cell?
Differentiation = Making specialized cells What is a stem cell? What the photo shows A lump of metal and lots of different kinds of screws. Things to think about Lumps of metal that start off the same
More informationCOLUMBIA UNIVERSITY POLICY ON THE CONDUCT OF RESEARCH WITH HUMAN EMBRYOS AND HUMAN EMBRYONIC STEM CELLS*
July 7, 2014 COLUMBIA UNIVERSITY POLICY ON THE CONDUCT OF RESEARCH WITH HUMAN EMBRYOS AND HUMAN EMBRYONIC STEM CELLS* A. INTRODUCTION Columbia University believes that human embryonic and human stem cell
More informationInformation for patients and the public and patient information about DNA / Biobanking across Europe
Information for patients and the public and patient information about DNA / Biobanking across Europe BIOBANKING / DNA BANKING SUMMARY: A biobank is a store of human biological material, used for the purposes
More informationStem Cells. Part 1: What is a Stem Cell?
Stem Cells Part 1: What is a Stem Cell? Stem cells differ from other kinds of cells in the body. When a stem cell divides by mitosis, each new cell has the potential to either remain a stem cell or become
More informationUnit 1 Higher Human Biology Summary Notes
Unit 1 Higher Human Biology Summary Notes a. Cells tissues organs body systems Division of labour occurs in multicellular organisms (rather than each cell carrying out every function) Most cells become
More information5. All cord blood banks should be subject to the same standards, regulations and accreditation requirements.
WMDA Policy Statement for the Utility of Autologous or Family Cord Blood Unit Storage (This policy statement has been approved and adopted by the WMDA board on the 25 th of May 2006) The Cord Blood Registries
More informationStem Cell Information
Stem Cell Information The official National Institutes of Health resource for stem cell research Stem Cell Basics Stem cells have the remarkable potential to develop into many different cell types in the
More information47/CNECV/05 STEM CELL RESEARCH
CONSELHO NACIONAL DE ÉTICA PARA AS CIÊNCIAS DA VIDA NATIONAL COUNCIL OF ETHICS FOR THE LIFE SCIENCES 47/CNECV/05 OPINION Nº 47 OF THE NATIONAL COUNCIL OF ETHICS FOR THE LIFE SCIENCES STEM CELL RESEARCH
More informationStem Cells. What Are Stem Cells? Sources for Stem Cells. Stem cells. Medical Ethics 1. Cells able to develop into nearly any other type of cell.
Stem Cells What Are Stem Cells? Cells able to develop into nearly any other type of cell. Adult stem cells found in skin, gut, blood Embryonic stem cells found in very early development of embryo (when
More informationAbortion and Stem Cell Debate Background Information
Abortion and Stem Cell Debate Background Information 1 Fetal Development 2 Terms Syngamy: fusion of two gametes in fertilization Zygote: name of the cell resulting from fertilization until it implants
More informationTop Ten Things to Know About Stem Cell Treatments
Top Ten Things to Know About Stem Cell Treatments Many clinics that are offering stem cell treatments make claims about what stem cells can and cannot do that are not supported by our understanding of
More informationTestimony of. Before The Subcommittee on Labor, Health and Human Services and Education of the Committee on Appropriations United States Senate
Testimony of James F. Childress, Ph.D. Commissioner, National Bioethics Advisory Commission and Kyle Professor of Religious Studies Professor of Medical Education University of Virginia Charlottesville,
More informationChapter 2 The different types of stem cells
Chapter 2 The different types of stem cells This chapter investigates the two main types of stem cells, each with their own subcategories: 1. Pluripotent stem cells can become any cell type in the body.
More informationRITMIR024 - STEM CELL RESEARCH IN CARDIOLOGY
1. SCOPE AND METHODOLOGY 2. REPORT SYNOPSIS 2.1 General Definitions Myoblasts Pluripotent Cells Multipotent Cells Progenitor Cells Role of Stem Cells in Repairing the Heart Stem Cell Therapy Stem Cells
More informationA cluster of 150 to 200 cells the typical number of cells comprising an embryo
Emma Roller J.404 jlb 10/6/10 A cluster of 150 to 200 cells the typical number of cells comprising an embryo used in stem-cell research may tip the scales to determine this fall s gubernatorial race. Like
More information[Indian Stem Cell Banking Market: Trends & Opportunities (2012-2017)]
[Indian Stem Cell Banking Market: Trends & Opportunities (2012-2017)] Executive Summary Stem Cells have a remarkable ability to develop in various body cells of a human. These occur in the earliest stages
More informationPharmacology skills for drug discovery. Why is pharmacology important?
skills for drug discovery Why is pharmacology important?, the science underlying the interaction between chemicals and living systems, emerged as a distinct discipline allied to medicine in the mid-19th
More informationNational Academy of Sciences National Academy of Engineering Institute of Medicine National Research Council
National Academy of Sciences National Academy of Engineering Institute of Medicine National Research Council IN THIS BOOKLET... WHAT IS A STEM CELL? 3 TYPES OF STEM CELLS 4 WORKING WITH STEM CELLS 9 WHY
More informationInternational Policies on Stem Cell Research
International Policies on Stem Cell Research Prof. Reza Nassiri Director, Institute of International Health Associate Dean of Global Health Programs College of Osteopathic Medicine Michigan State University
More informationCord blood banking: information for parents
Cord blood banking: information for parents Published August 2006 by the RCOG Contents Page number Key points 1 About this information 2 What is cord blood? 2 Why is cord blood useful? 3 How is cord blood
More informationEthical issues in stem cell research and application
Ethical issues in stem cell research and application Dr. Jeff Blackmer MD MHSc FRCPC Vice President Medical Professionalism Canadian Medical Association Ottawa, ON May 2016 Outline Ethics and stem cells
More informationDepartment of Legislative Services
Department of Legislative Services Maryland General Assembly 2006 Session HB 136 FISCAL AND POLICY NOTE House Bill 136 (Delegate Shewell, et al.) Health and Government Operations and Appropriations Public
More informationAre Muslims into stem cell research? Review of current available literature
Are Muslims into stem cell research? Review of current available literature Maysa Al-Hussaini and Linda Kateb King Hussein Cancer Center Amman Jordan No Disclosure What are the types of human stem cells?
More informationRationale: Revisions enhanced current content by shortening it through deletions of language
Total Number of Pages: 1 of 4 Rationale: Revisions enhanced current content by shortening it through deletions of language that occurs in other resolutions, such as 3182 Human Cloning. Amend Delete last
More informationHow To Change Medicine
P4 Medicine: Personalized, Predictive, Preventive, Participatory A Change of View that Changes Everything Leroy E. Hood Institute for Systems Biology David J. Galas Battelle Memorial Institute Version
More informationAP BIOLOGY 2012 SCORING GUIDELINES
AP BIOLOGY 2012 SCORING GUIDELINES Question 1 Note: At least 1 point must be earned from each of parts (a), (b), (c), and (d) in order to earn a maximum score of 10. The ability to reproduce is a characteristic
More informationEBiSC: The European Bank for induced pluripotent Stem Cells
EBiSC: The European Bank for induced pluripotent Stem Cells Sadallah Fatiha 30.10.2014 Japan Health Sciences Foundation Visit IMI JU Office, Brussels, Belgium EBiSC Establish a European repository for
More informationThe Ethics of Stem Cell Research and Prenatal Genetic Alteration
The Ethics of Stem Cell Research and Prenatal Genetic Alteration Blake Rodgers, Brandon Peterson Introduction Technological advancements associated with the medical industry create opportunities to conduct
More information1. Do Zombies have rights? 2. Do voodoo Zombies have different rights than virus Zombies? 5. Should Zombies be covered by universal health plans?
Exercise Nov. 22. Exam Nov. 29. Reproductive ethics No electronics PHIL 226 Biomedical Ethics Week 11 1 Zombie Ethics 1. Do Zombies have rights? 2. Do voodoo Zombies have different rights than virus Zombies?
More informationCORD BLOOD TRANSPLANTATION STUDY EXPANDED ACCESS PROTOCOL APPENDIX A SAMPLE CONSENT FORM
APPENDIX A SAMPLE CONSENT FORM CORD BLOOD TRANSPLANTATION (COBLT) STUDY SAMPLE CONSENT FORM FOR THE EXPANDED ACCESS PROTOCOL You (your child) are being asked to take part in a clinical research study.
More informationBiotechnology. Srivatsan Kidambi, Ph.D.
Stem Stem Cell Cell Engineering-What, Biology and it Application Why, How?? to Biotechnology Srivatsan Kidambi, Ph.D. Assistant Professor Department of Chemical & Biomolecular Engineering University of
More informationHUMAN FERTILISATION AND EMBRYOLOGY AUTHORITY REPORT:
HUMAN FERTILISATION AND EMBRYOLOGY AUTHORITY REPORT: Introduction 1. Preimplantation tissue typing is a new technique which allows the selection of embryos in order to bring about the birth of a child
More informationAlexander Smolyaninov,
«German-Russian Forum Biotechnology and Life Sciences» September, 2006 St. Petersburg Center of Cell and Gene Therapy «CRYOCENTER SAINT PETERSBURG» Stem Cell Bank «POKROVSKI» Alexander Smolyaninov, M.D.,Ph.D.,
More informationRegulatory Issues in Genetic Testing and Targeted Drug Development
Regulatory Issues in Genetic Testing and Targeted Drug Development Janet Woodcock, M.D. Deputy Commissioner for Operations Food and Drug Administration October 12, 2006 Genetic and Genomic Tests are Types
More informationInterstate Alliance on Stem Cell Research April 9-10, 2008 National Academy of Sciences Washington, D.C. Meeting Summary
April 9-10, 2008 National Academy of Sciences Washington, D.C. Meeting Summary Participants: States California Connecticut Illinois Massachusetts Maryland New Jersey New York Rhode Island Countries Canada
More informationA leader in the development and application of information technology to prevent and treat disease.
A leader in the development and application of information technology to prevent and treat disease. About MOLECULAR HEALTH Molecular Health was founded in 2004 with the vision of changing healthcare. Today
More informationCDRD and the MSSC Seek Collaborative Projects to Discover and Develop New Treatments for Progressive Multiple Sclerosis
CDRD and the MSSC Seek Collaborative Projects to Discover and Develop New Treatments for Progressive Multiple Sclerosis The Centre for Drug Research and Development (CDRD) and the Multiple Sclerosis Society
More informationRecent Developments in Governmental Regulation of Biomedicine in Japan. Eiji Maruyama Kobe University Graduate School of Law Kobe, Japan
Recent Developments in Governmental Regulation of Biomedicine in Japan Eiji Maruyama Kobe University Graduate School of Law Kobe, Japan A Law and Several Sets of Ethical Guidelines for Biomedicine in Japan
More informationCerebral Palsy. Information for patients. Cerebral Palsy Treatment With Stem Cells from your own Bone Marrow / Adipose Tissue
Information for patients Cerebral Palsy Treatment With Stem Cells from your own Bone Marrow / Adipose Tissue Cerebral Palsy Cerebral palsy is a neurological impairment principally causing loss or limitation
More informationDonating brain and spinal cord tissue for research
Donating brain and spinal cord tissue for research Thank you for taking the time to consider the donation of brain tissue for research into neurological diseases. Your interest in helping this research
More informationMarc Welc. Y1 Writes: A Collection of Student Essays 270
Y1 Writes: A Collection of Student Essays 270 Marc Welc Marc Welc graduated from Hiawatha High School, where he was actively involved in basketball, student council, National Honors Society, yearbook,
More information06 LC 14 9480S A BILL TO BE ENTITLED AN ACT
0 LC 0S The House Committee on Health and Human Services offers the following substitute to SB : A BILL TO BE ENTITLED AN ACT 0 To amend Title of the Official Code of Georgia Annotated, relating to health,
More informationIntroduction. Materials
Lesson 2 Techniques for Obtaining Stem Cells Objectives Students will be able to: Describe scientific techniques (IVF, therapeutic cloning, using cord blood and bone marrow, inducing pluripotent stem cells)
More informationSan Diego Stem Cell Treatment Center Frequently Asked Questions
San Diego Stem Cell Treatment Center Frequently Asked Questions What is a Stem Cell? A stem cell is basically any cell that can replicate and differentiate. This means the cell can not only multiply, but
More informationRegistries and Biobanks for Human Stem Cell Lines Glyn Stacey, UK Stem Cell Bank, NIBSC ESHRE Course, Valencia, 8 th November 2010
Registries and Biobanks for Human Stem Cell Lines Glyn Stacey, UK Stem Cell Bank, NIBSC ESHRE Course, Valencia, 8 th November 2010 National Institute for Biological Standards and Control Assuring the quality
More information