1. Biodegradable Polymers and Copolymers

Transcription

1 Cotet 1.1 Poly((R)-3-hydroxyalkaoate)s, (PB), atural polyers Low Molecular Weight PBs (LMW PB) PCL, PLA, PLGA polyers ad copolyers PB-b-PEG block copolyers (3-201-) BAB type triblock copolyers PB-b-PEG-b-PB (4-201-) Block copolyers of poly(ethylee glycol) ad poly(ϵ-caprolactoe) (PCL-b-PEG) (5-01-) BAB type triblock copolyers PCL-b-PEG-b-PCL (5-02-) ABA type PCL ad PEG block copolyers (PEG-PCL-PEG) (5-03-) Block copolyers of poly(ethylee glycol) ad poly(lactide) (PLA-b-PEG) (6-01-) BAB type triblock copolyers PLA-b-PEG-b-PLA, (6-02-) ABA type of PLA ad PEG block copolyers (PEG-PLA-PEG) (6-03-) Block copolyers of PEG ad PLGA (PLGA-b-PEG) (6-04-) BAB type of PLGA ad PEG block copolyers (PLGA-PEG-PLGA) (6-05-) ABA type of PLGA ad PEG block copolyers (PEG-PLGA-PEG)(6-06-) PE/PP AB type diblock copolyers (7-01-) PE/PP BAB type triblock copolyer (7-03-) PE/PB AB type diblock copolyers (8-01-) PE/PB BAB type triblock copolyers (8-03-) PE/PS AB type diblock copolyers (9-01-) PE/PS BAB type triblock copolyers (9-03-) Cyclic poly(oxyethylee) with acetal likage (10-01-) Cyclic poly(oxyethylee) large crow ether (10-02-) Cyclic block copolyers of ethylee oxide ad 1,2-butylee oxide (10-03-) 13 5 Fuctioal PCL, PLA, PLGA ad PEG block copolyers 14 6 Block copolyers ade fro aioic polyerizatio techique 19 7 Coductive polyers (P3T) 19 8 ther block copolyers 19 9 Poly(ethylee glycol) ethyl ether, PEGs Multi-ar PEGs Fuctioal PEGs Reactive PEGs 21

2 1. Biodegradable Polyers ad Copolyers 1.1. Poly((R)-3-hydroxyalkaoate)s (PA)s, atural polyers Cat # Product ae Molecular weight (Mw) Cheical Structure Poly((R)-3-hydroxybutyrate) [ ] Poly((R)-3-hydroxybutyrate/valerate) (10ol% V) Poly(3(R)-hydroxybutyrate/valerate) (20ol% V) C 2 5 x y 1.2. Low Molecular Weight Poly((R)-3-hydroxybutyrate) (LMW PB) PB-500 ~ PB-1000 ~ PB-1500 ~ PB-2000 ~ PB-2500 ~ PB-3000 ~ PB-4000 ~ PB-5000 ~ PB-6000 ~ PB-8000 ~ PB ~ The olecular weights (M, Mw, Mp) are deteried for each lot whe a product is produced PCL, PLA, PLGA polyers ad copolyers Poly(ε-caprolactoe)s (PCL) with differet olecular weights oo- ed: PCL-, Cat No.: PCL-XXXX; diols: -PCL-, Cat No.: PCL-XXXX Poly(d,l-lactide)s (PLA) ad poly(l-lactide)s (PLLA) with differet olecular weights oo- ed: PLA-, Cat No.: PLA-XXXX; diols: -PLA-, Cat No.: PLA-XXXX; oo- ed: PLLA-, Cat No.: PLLA-XXXX; diols: -PLLA-, Cat No.: PLLA-XXXX Poly(lactide/glycolide) (PLGA(x/y)) with differet ratios of LA to GA ad with differet olecular weights oo- ed: PLGA-, Cat No.: PLGA-x/y-XXXX; x/y is the olar ratio of LA to GA diols: -PLGA-, Cat No.: PLGA-x/y-XXXX, x/y is the olar ratio of LA to GA where xxxx is the olecular weight. ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 2 [email protected]

3 2. Biodegradable Block Copolyers 2.1. Poly((R)-3-hydroxybutyrate)-b-poly(ethylee glycol) block copolyers (PB-b-PEG) (3-201) /PEG PB(500)-b-PEG PB:500 / PEG: as required /PEG PB(1000)-b-PEG PB:1000 / PEG: as required /PEG PB(2000)-b-PEG PB:2000 / PEG: as required /PEG PB(3000)-b-PEG PB:3000 / PEG: as required /PEG PB(4000)-b-PEG PB:4000 / PEG: as required /PEG PB(5000)-b-PEG PB:5000 / PEG: as required PEG olecular weight could be selected fro 350, 750, 1k, 2k, 3k, 4k, 5k, etc. The olecular weights of a product are deteried for each lot whe it is produced Poly((R)-3-hydroxybutyrate)-b-poly(ethylee glycol)-b-poly((r)-3-hydroxybutyrate) triblock copolyers (PB-b-PEG-b-PB) (4-201-) PB/600/PB PB-b-PEG(600)-b-PB PB: as required / PEG: PB/1000/PB PB-b-PEG(1000)-b-PB PB: as required / PEG: PB/2000/PB PB-b-PEG(2000)-b-PB PB: as required / PEG: PB/4000/PB PB-b-PEG(4000)-b-PB PB: as required / PEG: PB/6000/PB PB-b-PEG(6000)-b-PB PB: as required / PEG: PB/8000/PB PB-b-PEG(8000)-b-PB PB: as required / PEG: PB/10000/PB PB-b-PEG(10K)-b-PB PB: as required / PEG: Block copolyers ca be ordered with specified olecular weight ad olecular weight ratio. ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 3 [email protected]

4 2.3. Block copolyers of poly(ethylee glycol) ad poly(ε-caprolactoe) (PCL-b-PEG or PEG-b-PCL) (5-01-) Me 5-01-PCL/350 PCL-b-PEG(350) PCL: as required /PEG: PCL/750 PCL-b-PEG(750) PCL: as required /PEG: PCL/1000 PCL-b-PEG(1000) PCL: as required /PEG: PCL/2000 PCL-b-PEG(2000) PCL: as required /PEG: PCL/3000 PCL-b-PEG(3000) PCL: as required /PEG: PCL/4000 PCL-b-PEG(4000) PCL: as required /PEG: PCL/5000 PCL-b-PEG(5000) PCL: as required /PEG: PCL/6000 PCL-b-PEG(6000) PCL: as required /PEG: PCL/7500 PCL-b-PEG (7500) PCL: as required /PEG: PCL/10000 PCL-b-PEG(10000) PCL: as required / PEG: PCL/PEG PCL-b-PEG PCL: as required/ PEG: as required rders ca be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 2.4 PCL-b-PEG-b-PCL BAB type triblock copolyers (5-02-) 5-02-PCL/300/PCL PCL-b-PEG(300)-b-PCL PCL: as required / PEG: PCL/600/PCL PCL-b-PEG(600)-b-PCL PCL: as required / PEG: PCL/1000/PCL PCL-b-PEG(1000)-b-PCL PCL: as required / PEG: PCL/1500/PCL PCL-b-PEG(1500)-b-PCL PCL: as required / PEG: PCL/2000/PCL PCL-b-PEG(2000)-b-PCL PCL: as required / PEG: PCL/4000/PCL PCL-b-PEG(4000)-b-PCL PCL: as required / PEG: ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 4 [email protected]

5 5-02-PCL/6000/PCL PCL-b-PEG(6000)-b-PCL PCL: as required / PEG: PCL/8000/PCL PCL-b-PEG(8000)-b-PCL PCL: as required / PEG: PCL/10000/PCL PCL-b-PEG(10000)-b-PCL PCL: as required / PEG: PCL/20000/PCL PCL-b-PEG(20000)-b-PCL PCL: as required / PEG: rders ca be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 2.5 Triblock copolyers of poly(ε-caprolactoe) with ethoxypoly(ethylee glycol) (PEG-PCL-PEG) (5-03-) L Me Me /PCL/1000 PEG(1000)-b-PCL-PEG(1000) PCL: as required / PEG: /PCL/2000 PEG(2000)-b-PCL-PEG(2000) PCL: as required / PEG: /PCL/5000 PEG(5000)-b-PCL-b-PEG(5000) PCL: as required / PEG: rders ca be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 2.6 Diblock copolyers of poly(ethylee glycol) ad poly(lactide) (PEG-b-PLA or PLA-b-PEG) (6-01-) Me 6-01-PLA/350 PLA-b-PEG (350) or PEG(350)-b-PLA PLA: as required/peg: PLA/750 PLA-b-PEG (750) PLA: as required/peg: PLA/1000 PLA-b-PEG (1000) PLA: as required /PEG: PLA/2000 PLA-b-PEG (2000) PLA: as required /PEG: PLA/3000 PLA-b-PEG (3000) PLA: as required /PEG: PLA/4000 PLA-b-PEG (4000) PLA: as required /PEG: PLA/5000 PLA-b-PEG (5000) PLA: as required /PEG: PLA/6000 PLA-b-PEG (6000) PLA: as required /PEG: ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 5 [email protected]

6 6-01-PLA/7500 PLA-b-PEG (7500) PLA: as required /PEG: PLA/10000 PLA-b-PEG (10000) PLA: as required /PEG: PLA/20000 PLA-b-PEG (20000) PLA: as required /PEG: rders ca be placed with specified olecular weight ad olecular ratios, eve for those ot listed. ere PLA eas poly(d,l-lactide) You ca also place a order for poly(l-lactide) block copolyers, for exaple, PLLA(10k)-PEG(5k) Poly(lactide)-b-poly(ethylee glycol)-b-poly(lactide) BAB type triblock copolyers (6-02-) 6-02-PLA/300/PLA PLA-b-PEG(300)-b-PLA PLA: as require / PEG: PLA/600/PLA PLA-b-PEG(600)-b-PLA PLA: as require / PEG: PLA/1000/PLA PLA-b-PEG(1000)-b-PLA PLA: as require / PEG: PLA/1500/PLA PLA-b-PEG(1500)-b-PLA PLA: as require / PEG: PLA/2000/PLA PLA-b-PEG(2000)-b-PLA PLA: as require / PEG: PLA/4000/PLA PLA-b-PEG(4000)-b-PLA PLA: as require / PEG: PLA/6000/PLA PLA-b-PEG(6000)-b-PLA PLA: as require / PEG: PLA/8000/PLA PLA-b-PEG(8000)-b-PLA PLA: as require / PEG: PLA/10000/PLA PLA-b-PEG(10000)-b-PLA PLA: as require / PEG: PLA/20000/PLA PLA-b-PEG(20000)-b-PLA PLA: as require / PEG: rders ca be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 2.8 Triblock copolyers of poly(lactide) with ethoxypoly(ethylee glycol) (PEG-PLA-PEG) (6-03-) Me L Me /PLA/350 PEG(350)-b-PLA-PEG(350) PLA: as required / PEG: ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 6 [email protected]

7 /PLA/750 PEG(750)-b-PLA-PEG(750) PLA: as required / PEG: /PLA/1000 PEG(1000)-b-PLA-PEG(1000) PLA: as required / PEG: /PLA/2000 PEG(2000)-b-PLA-PEG(2000) PLA: as required / PEG: /PLA/3000 PEG(3000)-b-PLA-b-PEG(3000) PLA: as required / PEG: /PLA/4000 PEG(4000)-b-PLA-b-PEG(4000) PLA: as required / PEG: /PLA/5000 PEG(5000)-b-PLA-b-PEG(5000) PLA: as required / PEG: /PLA/7500 PEG(7500)-b-PLA-b-PEG(7500) PLA: as required / PEG: k/PLA/10k PEG(10k)-b-PLA-b-PEG(10k) PLA: as required / PEG: 10k PEG/PLA/PEG PEG-b-PLA-b-PEG PLA: as required / PEG: as required rders ca be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 2.9 Diblock copolyers of poly(ethylee glycol) ad poly(lactide/glycolide) (PEG-b-PLGA or PLGA-b-PEG) (6-04-) Me x y 6-04-x/y-PLGA/350 PLGA(x/y)-b-PEG (350) or PEG(350)-b-PLGA(x/y) PLGA(x/y): as required/peg: x/y-plga /750 PLGA(x/y)-b-PEG (750) PLGA(x/y): as required/peg: x/y-plga /1000 PLGA(x/y)-b-PEG (1000) PLGA(x/y): as required /PEG: x/y-plga /2000 PLGA(x/y)-b-PEG (2000) PLGA(x/y): as required /PEG: x/y-plga /3000 PLGA(x/y)-b-PEG (3000) PLGA(x/y): as required /PEG: x/y-plga /4000 PLGA(x/y)-b-PEG (4000) PLGA(x/y): as required /PEG: x/y-plga /5000 PLGA(x/y)-b-PEG (5000) PLGA(x/y): as required /PEG: x/y-plga /6000 PLGA(x/y)-b-PEG (6000) PLGA(x/y): as required /PEG: x/y-plga /7500 PLGA(x/y)-b-PEG (7500) PLGA(x/y): as required /PEG: x/y-plga /10000 PLGA(x/y)-b-PEG (10000) PLGA(x/y): as required /PEG: x/y-plga /20000 PLGA(x/y)-b-PEG (20000) PLGA(x/y): as required /PEG: ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 7 [email protected]

8 Where x/y is the ratio of LA to GA. For exaple, 85/15, 75/25, 50/50, etc rders ca be placed with specified olecular weight ad olecular ratios, eve for those ot listed Triblock copolyers of poly(ethylee glycol) ad poly(lactide/glycolide) (PLGA-b-PEG-b-PLGA) (6-05-) y x x y 6-05-x/y-PLGA/300/PLGA PLGA(x/y)-b-PEG(300)-b-PLGA(x/y) PLGA(x/y): as require / PEG: x/y-plga/600/plga PLGA(x/y)-b-PEG(600)-b-PLGA(x/y) PLGA(x/y): as require / PEG: x/y-plga/1000/plga PLGA(x/y)-b-PEG(1000)-b-PLGA(x/y) PLGA(x/y): as require / PEG: x/y-plga/1500/plga PLGA(x/y)-b-PEG(1500)-b-PLGA(x/y) PLGA(x/y): as require / PEG: x/y-plga/2000/plga PLGA(x/y)-b-PEG(2000)-b-PLGA(x/y) PLGA(x/y): as require / PEG: x/y-plga/4000/plga PLGA(x/y)-b-PEG(4000)-b-PLGA(x/y) PLGA(x/y): as require / PEG: x/y-plga/6000/plga PLGA(x/y)-b-PEG(6000)-b-PLGA(x/y) PLGA(x/y): as require / PEG: x/y-plga/8000/plga PLGA(x/y)-b-PEG(8000)-b-PLGA(x/y) PLGA(x/y): as require / PEG: x/y-plga/10000/plga PLGA(x/y)-b-PEG(10000)-b-PLGA(x/y) PLGA(x/y): as require / PEG: x/y-plga/20000/plga PLGA(x/y)-b-PEG(20000)-b-PLGA(x/y) PLGA(x/y): as require / PEG: Where x/y is the ratio of LA to GA. For exaple, 85/15, 75/25, 50/50, etc rders ca be placed with specified olecular weight ad olecular ratios, eve for those ot listed Triblock copolyers of poly(lactide/glycolide) with ethoxypoly(ethylee glycol) (PEG-PLGA-PEG) (6-06-) L 3 C y x x y 6-06-x/y-350/PLGA/350 PEG(350)-b-PLGA-PEG(350) PLGA(x/y): as required / PEG: x/y-750/PLGA/750 PEG(750)-b-PLGA-PEG(750) PLGA(x/y): as required / PEG: x/y-1000/PLGA/1000 PEG(1000)-b-PLGA-PEG(1000) PLGA(x/y): as required / PEG: x/y-2000/PLGA/2000 PEG(2000)-b-PLGA-PEG(2000) PLGA(x/y): as required / PEG: x/y-3000/PLGA/3000 PEG(3000)-b-PLGA-b-PEG(3000) PLGA(x/y): as required / PEG: ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 8 [email protected]

9 6-06-x/y-4000/PLGA/4000 PEG(4000)-b-PLGA-b-PEG(4000) PLGA(x/y): as required / PEG: x/y-5000/PLGA/5000 PEG(5000)-b-PLGA-b-PEG(5000) PLGA(x/y): as required / PEG: x/y-7500/PLGA/7500 PEG(7500)-b-PLGA-b-PEG(7500) PLGA(x/y): as required / PEG: x/y-10k/PLGA/10k PEG(10k)-b-PLGA-b-PEG(10k) PLGA(x/y): as required / PEG: 10k x/y-PEG/PLGA/PEG PEG-b-PLGA(x/y)-b-PEG PLGA(x/y): as required / PEG: as required Where x/y is the ratio of LA to GA. For exaple, 85/15, 75/25, 50/50, etc rders ca be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 3. xirae Block Copolyers 3.1. PE/PP AB type diblock copolyers (PE-b-PP or PP-b-PE) (7-01-) / (E) 8 -(P) PE: 350; PP: as required / (E) 17 -(P) PE: 750; PP: as required / (E) 23 -(P) PE: 1000; PP: as required / (E) 45 -(P) PE: 2000; PP: as required / (E) 68 -(P) PE: 3000; PP: as required / (E) 90 -(P) PE: 4000; PP: as required / (E) 114 -(P) PE: 5000; PP: as required / (E) 136 -(P) PE: 6000; PP: as required / (E) 170 -(P) PE: 7500; PP: as required / (E) 227 -(P) PE: 10000; PP: as required / (E) 454 -(P) PE: 20000; PP: as required 1.1 rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed PE/PP BAB type triblock copolyer (7-03-) ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 9 [email protected]

10 7-03-/8/ poly(oxypropylee)-b-poly(oxyethylee)- b-poly(oxypropylee) (P) -(E) 7 -(P) PP: as required /PE: /14/ (P) -(E) 14 -(P) PP: as required /PE: /23/ (P) -(E) 23 -(P) PP: as required / PE: /45/ (P) -(E) 45 -(P) PP: as required / PE: /90/ (P) -(E) 90 -(P) PP: as required / PE: /136/ (P) -(E) 136 -(P) PP: as required / PE: /181/ (P) -(E) 181 -(P) PP: as required / PE: /225/ (P) -(E) 225 -(P) PP: as required / PE: /450/ (P) -(E) 450 -(P) PP: as required / PE: rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed PE/PB AB type diblock copolyers (PE-b-PB or PB-b-PE) (8-01-) C / poly(oxyethylee)-b-poly(oxybutylee) PE: 350; PB: as required 1.1 (E) 8 -(B) / (E) 17 -(B) PE: 750; PB: as required / (E) 23 -(B) PE: 1000; PB: as required / (E) 45 -(B) PE: 2000; PB: as required / (E) 68 -(B) PE: 3000; PB: as required / (E) 90 -(B) PE: 4000; PB: as required / (E) 114 -(B) PE: 5000; PB: as required / (E) 136 -(B) PE: 6000; PB: as required / (E) 170 -(B) PE: 7500; PB: as required / (E) 227 -(B) PE: 10000; PB: as required 1.1 ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 10 [email protected]

11 / (E) 454 -(B) PE: 20000; PB: as required 1.1 rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed PE/PB BAB type triblock copolyers (8-03-) C 2 3 C /8/ poly(oxybutylee)-b-poly(oxyethylee)-bpoly(oxybutylee) PB: as required / PE: or (B) -(E) 7 -(B) 8-03-/17/ (B) -(E) 14 -(B) PB: as required / PE: /23/ (B) -(E) 23 -(B) PB: as required / PE: /45/ (B) -(E) 45 -(B) PB: as required / PE: /90/ (B) -(E) 90 -(B) PB: as required / PE: /136/ (B) -(E) 136 -(B) PB: as required / PE: /181/ (B) -(E) 181 -(B) PB: as required / PE: /225/ (B) -(E) 225 -(B) PB: as required / PE: /450/ (B) -(E) 450 -(B) PB: as required / PE: rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed PE/PS AB type diblock copolyers (PE-b-PS or PS-b-PE) (9-01-) / poly(oxyethylee)-b-poly(oxystylee) PE-b-PS (350/600) or (E) 8 -(S) 5 PE: 350; PS: as required / (E) 17 -(S) PE: 750; PS: as required / (E) 23 -(S) PE: 1000; PS: as required / (E) 45 -(S) PE: 2000; PS: as required / (E) 68 -(S) PE: 3000; PS: as required 1.1 ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 11 [email protected]

12 / (E) 114 -(S) PE: 4000; PS: as required / (E) 114 -(S) PE: 5000; PS: as required / (E) 136 -(S) PE: 6000; PS: as required / (E) 170 -(S) PE: 7500; PS: as required / (E) 227 -(S) PE: 10000; PS: as required / (E) 450 -(S) PE: 20000; PS: as required 1.1 rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed PE/PS BAB type triblock copolyers (9-03-) 9-03-/23/ series poly(oxystylee)-b-poly(oxyethylee)-bpoly(oxystylee) PS-b-PE-b-PS (S) -(E) 23 -(S) PS: as required /PE: /45/ series (S) -(E) 45 -(S) PS: as required /PE: /90/ (S) -(E) 90 -(S) PS: as required /PE: /136/ (S) -(E) 136 -(S) PS: as required /PE: /181/ (S) -(E) 181 -(S) PS: as required /PE: /225/ (S) -(E) 225 -(S) PS: as required /PE: /450/ (S) -(E) 450 -(S) PS: as required /PE: rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 4. Cyclic Polyers ad Copolyers 4.1. Cyclic poly(oxyethylee) with acetal likage (10-01) C 2 C 2 C 2 Cat # Product ae Molecular weight (M) Purity ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 12 [email protected]

13 Cyclo-poly(oxyethylee)-600 PE: 600 >90 % Cyclo-poly(oxyethylee)-1000 PE: 1000 >90 % Cyclo-poly(oxyethylee)-1500 PE: 1500 >90 % Cyclo-poly(oxyethylee)-2000 PE: 2000 >90 % Cyclo-poly(oxyethylee)-4000 PE: 4000 >90 % Cyclo-poly(oxyethylee)-6000 PE: 6000 >90 % Cyclo-poly(oxyethylee)-8000 PE: 8000 >90 % Cyclo-poly(oxyethylee) PE: >90 % Cyclo-poly(oxyethylee) PE: >90 % For quotes, or ay other iquiries, feel free to cotact us at [email protected] 4.2. Cyclic poly(oxyethylee) large crow ether (10-02) C 2 C 2 Cat # Product ae Molecular weight (M) Purity Cyclo-poly(oxyethylee)-600 PE: 600 >90 % Cyclo-poly(oxyethylee)-1000 PE: 1000 >90 % Cyclo-poly(oxyethylee)-1500 PE: 1500 >90 % Cyclo-poly(oxyethylee)-2000 PE: 2000 >90 % Cyclo-poly(oxyethylee)-4000 PE: 4000 >90 % Cyclo-poly(oxyethylee)-6000 PE: 6000 >90 % Cyclo-poly(oxyethylee)-8000 PE: 8000 >90 % Cyclo-poly(oxyethylee) PE: >90 % For quotes, or ay other iquiries, feel free to cotact us at [email protected] 4.3. Cyclic bloc copolyers of poly(ethylee oxide) ad poly(1,2-butylee oxide) (10-03) (E) (B) (E) C 2 Cat # Product ae Molecular weight (M) Purity ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 13 [email protected]

14 / Cyclo-poly(oxyethylee)-bpoly(oxybutylee) (2/) 2/ >90 % Please specify the olecular weight whe you order these cyclics Cyclic bloc copolyers of poly(ethylee oxide) ad poly(propylee oxide) (10-04) (E) (P) (E) C 2 Cat # Product ae Molecular weight (M) Purity / Cyclo-poly(oxyethylee)-bpoly(oxypropylee) (2/) 2/ >90 % Please specify the olecular weight whe you order these cyclics. 5. Fuctioal biodegradable block copolyers 5.1 poly(ε-caprolactoe) with poly(ethylee glycol) with hydroxyl ed (-PEG-b-PCL or PCL-b-PEG-) ( ) PCL/1000 PCL-b-PEG- (1000) PCL: as required/-peg: PCL/2000 PCL-b-PEG- (2000) PCL: as required/-peg: PCL/3000 PCL-b-PEG- (3000) PCL: as required /-PEG: PCL/4000 PCL-b-PEG- (4000) PCL: as required /-PEG: PCL/5000 PCL-b-PEG- (5000) PCL: as required /-PEG: PCL/6000 PCL-b-PEG- (6000) PCL: as required /-PEG: poly(ε-caprolactoe) with poly(ethylee glycol) with carboxylic acid ed (C-PEG-b-PCL or PCL-b- PEG-C) (11-01-CX-) C CX-PCL/1000 PCL-b-PEG-C (1000) PCL: as required/c-peg: ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 14 [email protected]

15 11-01-CX-PCL/2000 PCL-b-PEG-C (2000) PCL: as required/c-peg: CX-PCL/3000 PCL-b-PEG-C (3000) PCL: as required /C-PEG: CX-PCL/4000 PCL-b-PEG-C (4000) PCL: as required /C-PEG: CX-PCL/5000 PCL-b-PEG-C (5000) PCL: as required /C-PEG: CX-PCL/6000 PCL-b-PEG-C (6000) PCL: as required /C-PEG: rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 5.3 poly(ε-caprolactoe) with poly(ethylee glycol) with aleiide ed (MAL-PEG-b-PCL or PCL-b-PEG- MAL) (11-01-MAL-) N C MAL-PCL/1000 PCL-b-PEG-MAL (1000) PCL: as required/mal-peg: MAL-PCL/2000 PCL-b-PEG-MAL (2000) PCL: as required/mal-peg: MAL-PCL/3000 PCL-b-PEG-MAL (3000) PCL: as required /MAL-PEG: MAL-PCL/4000 PCL-b-PEG-MAL (4000) PCL: as required /MAL-PEG: MAL-PCL/5000 PCL-b-PEG-MAL (5000) PCL: as required /MAL-PEG: MAL-PCL/6000 PCL-b-PEG-MAL (6000) PCL: as required /MAL-PEG: rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 5.4 poly(ε-caprolactoe) with poly(ethylee glycol) with aie ed ( 2 N-PEG-b-PCL or PCL-b-PEG-N 2 ) (11-01-N2-) N N2-PCL/2000 PCL-b-PEG-N 2 (2000) PCL: as required/ 2 N-PEG: N2-PCL/3000 PCL-b-PEG-N 2 (3000) PCL: as required / 2 N-PEG: N2-PCL/4000 PCL-b-PEG-N 2 (4000) PCL: as required / 2 N-PEG: N2-PCL/5000 PCL-b-PEG-N 2 (5000) PCL: as required / 2 N-PEG: ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 15 [email protected]

16 11-01-N2-PCL/6000 PCL-b-PEG-N 2 (6000) PCL: as required / 2 N-PEG: rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 5.5 poly(d,l-lactide) with poly(ethylee glycol) with hydroxyl ed (-PEG-b-PLA or PLA-b-PEG-) ( ) PLA/1000 PLA-b-PEG- (1000) PLA: as required/-peg: PLA/2000 PLA-b-PEG- (2000) PLA: as required/-peg: PLA/3000 PLA-b-PEG- (3000) PLA: as required /-PEG: PLA/4000 PLA-b-PEG- (4000) PLA: as required /-PEG: PLA/5000 PLA-b-PEG- (5000) PLA: as required /-PEG: PLA/6000 PLA-b-PEG- (6000) PLA: as required /-PEG: rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 5.6 poly(d,l-lactide) with poly(ethylee glycol) with carboxylic acid ed (C-PEG-b-PLA or PLA-b-PEG- C) (12-01-CX-) C CX-PLA/1000 PLA-b-PEG-C (1000) PLA: as required/c-peg: CX-PLA/2000 PLA-b-PEG-C (2000) PLA: as required/c-peg: CX-PLA/3000 PLA-b-PEG-C (3000) PLA: as required /C-PEG: CX-PLA/4000 PLA-b-PEG-C (4000) PLA: as required /C-PEG: CX-PLA/5000 PLA-b-PEG-C (5000) PLA: as required /C-PEG: CX-PLA/6000 PLA-b-PEG-C (6000) PLA: as required /C-PEG: rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed. ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 16 [email protected]

17 5.7 poly(d,l-lactide) with poly(ethylee glycol) with aleiide ed (MAL-PEG-b-PLA or PLA-b-PEG-MAL) (12-01-MAL-) N C MAL-PLA/2000 PLA-b-PEG-MAL (2000) PLA: as required/mal-peg: MAL-PLA/3000 PLA-b-PEG-MAL (3000) PLA: as required/mal-peg: MAL-PLA/4000 PLA-b-PEG-MAL (4000) PLA: as required /MAL-PEG: MAL-PLA/5000 PLA-b-PEG-MAL (5000) PLA: as required /MAL-PEG: MAL-PLA/6000 PLA-b-PEG-MAL (6000) PLA: as required /MAL-PEG: rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 5.8 Poly(d,l-Lactide) with poly(ethylee glycol) with aie ed ( 2 N-PEG-b-PLA or PLA-b-PEG-N 2 ) (12-01-N2-) N N2-PLA/2000 PLA-b-PEG-N 2 (2000) PLA: as required/ 2 N-PEG: N2-PLA/3000 PLA-b-PEG-N 2 (3000) PLA: as required / 2 N-PEG: N2-PLA/4000 PLA-b-PEG-N 2 (4000) PLA: as required / 2 N-PEG: N2-PLA/5000 PLA-b-PEG-N 2 (5000) PLA: as required / 2 N-PEG: N2-PLA/6000 PLA-b-PEG-N 2 (6000) PLA: as required / 2 N-PEG: rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed. 5.9 Poly(Lactide/glycolide) with poly(ethylee glycol) with -C ed (C-PEG-b-PLGA or PLGA-b- PEG-C) (13-01-CX-) C x y CX-x/y-PLGA / CX-x/y-PLGA /3000 PLGA(x/y)-b-PEG-C (2k) PLGA(x/y): as required/c-peg: 2k PLGA(x/y)-b-PEG-C (3k) PLGA(x/y): as required/c-peg: 3k ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 17 [email protected]

18 13-01-CX-x/y-PLGA / CX-x/y-PLGA /5000 PLGA(x/y)-b-PEG-C (4k) PLGA(x/y): as required /C-PEG: 4k PLGA(x/y)-b-PEG-C (5k) PLGA(x/y): as required /C-PEG: 5k rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed Poly(Lactide/glycolide) with poly(ethylee glycol) with aleiide ed (MAL-PEG-b-PLGA or PLGA-b- PEG-MAL) (13-01-MAL-) MAL-x/y-PLGA / MAL-x/y-PLGA / MAL-x/y-PLGA / MAL-x/y-PLGA /6000 PLGA(x/y)-b-PEG-MAL (2k) PLGA(x/y): as required/mal-peg: 2k PLGA(x/y)-b-PEG-MAL (4k) PLGA(x/y): as required /MAL-PEG: 4k PLGA(x/y)-b-PEG-MAL (5k) PLGA(x/y): as required /MAL-PEG: 5k PLGA(x/y)-b-PEG-MAL (6k) PLGA(x/y): as required /MAL-PEG: 6k rders ay be placed with specified olecular weight ad olecular ratios, eve for those ot listed Poly(Lactide/glycolide) with poly(ethylee glycol) with aie ed ( 2 N-PEG-b-PLGA or PLGA-b-PEG- N2) (13-01-N2-) N2-x/y-PLGA / N2-x/y-PLGA / N2-x/y-PLGA /5000 N N 2 C x x PLGA(x/y)-b-PEG-N 2 (2k) PLGA(x/y): as required/ 2 N-PEG: 2k PLGA(x/y)-b-PEG-N 2 (3k) PLGA(x/y): as required/ 2 N-PEG: 3k PLGA(x/y)-b-PEG-N 2 (5k) PLGA(x/y): as required / 2 N-PEG: 5k y y We do custo sythesis of the fuctioal block copolyers, please specify the olecular weight for each block ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 18 [email protected]

19 6. Block copolyers ade fro aioic polyerizatio techique 6.1 Poly(styree) with poly(ethylee oxide) (PS-b-PE) (14-01-) k/PE PS(10k)-b-PE PS: 10k; PE: as required k/PE PS(50k)-b-PE PS: 50k; PE: as required Poly(ethylethacrylate) with poly(ethylee oxide) (PMMA-b-PE) (15-01-) k/PE PMMA(10k)-b-PE PMMA: 10k; PE: as required k/PE PMMA(50k)-b-PE PMMA: 50k; PE: as required Poly(styree) with Poly(ethyl ethacrylate), PS-b-PMMA (16-01-) k/PMMA PS(50k)-b-PMMA PS: 50k; PMMA: as required k/PMMA PS(100k)-b-PMMA PS: 100k; PMMA: as required Poly(styree) with poly(4-viylpyridie) (PS-b-P4VP) (17-01-) k/P4VP PS(10k)-b-P4VP PS: 10k; P4VP: as required k/P4VP PS(50k)-b-P4VP PS: 50k; P4VP: as required Poly(styree) with poly(acrylic acid) (PS-b-PAA) (18-01-) k/PAA PS(50k)-b-PAA PS: 50k; PAA: as required k/PAA PS(100k)-b-PAA PS: 100k; PAA: as required 1.1 These lists are oly exaples, please specify your olecular weight for each block. 7. Coductive Polyers We supply P3T polyer with differet olecular weights (10k, 20k, 30k, 40k, etc) catalogue uber: P3T-XXXX, where xxxx is the olecular weight. 8. ther polyers We also supply a lot of other polyers such as PMMA-b-PCL; PMMA-b-PLA; PAA-b-PCL; PAA-b-PLA; PE-b-PAA; PE-b-P4VP-b-PS; etc. Please sed your requests to us. ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 19 [email protected]

20 PEG series We supply ethoxy polyethylee glycol with differet olecular weights for your R&D ad productio. Molecular weight rage: 350 to Catalog Nuber: PEG-XXXX, where XXXX stads for uber average olecular weight (M). PEG-350 PEG-550 PEG-750 PEG-1000 PEG-2000 PEG-3000 PEG-4000 PEG-5000 PEG-6000 PEG-7500 PEG PEG PEG PEG Multi-ar PEGs We supply ulti-ar PEGs or brached PEGs, icludig 3-ar PEG, 4-ar PEG, 6-ar PEG with required olecular weights. Catalog Nuber : 3-ar PEG-xxxx, 4-ar PEG-xxxx, 6-ar PEG-xxxx, where xxxx stads for uber average olecular weight (M). Molecular weights rage: 2k up. Fuctioal PEGs We supply fuctioal PEGs with fuctioal groups such as C, -N 2, -S, -S 3, -aleiide, etc. The followig list shows soe exaples. PEG-C Catalogue uber: PEG-CX-XXXX. Molecular weight rage: 350 to PEG-CNS Catalogue uber: PEG-NS-XXXX. Molecular weight rage: 350 to C-PEG-C Catalogue uber: PEG-diCX-XXXX, olecular weight rage 200 to PEG-N 2 Catalogue uber: PEG-N2-XXXX, olecular weight rage: 350 to N-PEG-N 2 Catalogue uber: PEG-diN2-XXXX, olecular weight rage: 200 to PEG-N 3 catalogue uber: PEG-N3-XXXX, olecular weight rage: 350 to N 3 -PEG-N 3 catalogue uber: PEG-diN3-XXXX, olecular weight rage: 200 to PEG-aleiide catalogue uber: PEG-MAL-XXXX, olecular weight rage: 350 to Fuctioal ulti-ar PEGs 3-ar PEG-C, catalogue uber: 3-ar-PEG-CX-XXXX 4-ar PEG-C, catalogue uber: 4-ar-PEG-CX-XXXX 6-ar PEG-C, catalogue uber: 6-ar-PEG-CX-XXXX 3-ar PEG-N 2, catalogue uber: 3-ar-PEG-N2-XXXX 4-ar PEG-N 2, catalogue uber: 4-ar-PEG-N2-XXXX 6-ar PEG-N 2, catalogue uber: 6-ar-PEG-N2-XXXX eterofuctioal PEGs -PEG-C Catalogue uber: PEG-CX-XXXX -PEG-N 2 Catalogue uber: PEG-N2-XXXXX -PEG-S 3 Na Catalogue uber: PEG-S3-XXXX We accept orders for custo-desiged fuctioal PEGs. ADVANCED PLYMER MATERIALS INC. Provides bioaterials ad polyer techologies 20 [email protected]