IMMUNOCHEMICALS - A Global Strategic Business Report

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1 /wepdwukltuyot IMMUNOCHEMICALS - A Global Strategic Business Report 联 系 购 买 电 话 : 公 司 名 称 : 佐 思 信 息 公 司 地 址 : 北 京 市 海 淀 区 苏 州 街 18 号 院 长 远 天 地 大 厦 A2 座 室 (100080) 出 版 日 期 :April 2011 This report analyzes the worldwide markets for Immunochemicals in US$ million by the following product segments?catalog Antibodies, and Custom Antibodies. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, China and Rest of World. Annual estimates and forecasts are provided for the period 2009 through Also, a six-year historic analysis is provided for these markets. The report profiles 100 companies including many key and niche players such as Abbott Diagnostics, Advanced ImmunoChemical, Beckman Coulter, Inc., BioCat GmbH, BIOTREND Chemikalien GmbH, Bio- Rad Laboratories, Inc., Dako, Life Technologies Corporation, Maine Biotechnology Services, Meridian Life Science? Inc., Millipore Corporation, MitoSciences, Inc., MorphoSys AG, Randox Laboratories Ltd., Roche Group, Rockland Immunochemicals, Sigma-Aldrich Co., And Trinity Biotech, PLC. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources. TABLE OF CONTENTS IMMUNOCHEMICALS (Complete Report) Pages : INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS...14 Study Reliability and Reporting Limitations...1 Disclaimers...2 Data Interpretation & Reporting Level...3 Quantitative Techniques & Analytics...3 Product Definitions and Scope of Study...3 Catalog Antibodies...4

2 Custom Antibodies INDUSTRY OVERVIEW...55 Escalating Demand for Immunochemicals...5 Antibodies: Critical Role in Drug Discovery and Research...51 Animal-Based Technologies Lose Ground to Alternative Approaches...6 Current and Future Analysis...61 Emerging Markets Offer Huge Potential...7 Custom Antibodies: Finding Favor in Research Applications...7 Research Antibodies?Linked to Prospects of Therapeutic Antibody Market...71 Antibody Manufacturers Face Threat from Academics Sector...8 Table 1: Global Immunochemicals Market (2010E): Percentage Share Breakdown of Revenues by Sector for Academia and Pharmaceutical/Biotech...8 Competitive Scenario...81 Factors Affecting Competitiveness of Players in the Global Immunochemicals Market? &nbspranked by Importance for Purchasers AN INTRODUCTION TO IMMUNOCHEMICALS Immunochemicals...10 Types of Immunochemicals...10 Catalog Antibodies...10 Custom Antibodies Applications of Immunochemicals...11 Healthcare...11 Environmental Science...11

3 Crop Protection and Biotechnology...11 Leading Research Areas Table 2: Leading Research Areas in the Global Immunochemicals Market (2010E): Percentage Share Breakdown for Immunology, Neurobiology, Signal Transduction, Developmental Biology, Cardiovascular, Virology, Stem Cells, Microbiology, and Others (includes corresponding Graph/Chart)...12 Common Techniques Used for Research in the Global Immunochemicals Market ANTIBODIES?A PRIMER Introduction to Antibodies...13 Primary and Secondary Antibodies Antibodies in Research Applications Table 3: Antibody Usage in Research Sector (2008): Percentage Share Breakdown of Revenues by Platform for Flow Cytometry, ELISA, Protein Arrays, and Others (includes corresponding Graph/Chart)...15 Monoclonal Antibodies...15 Properties Applications...16 Polyclonal Antibodies...16 Production Process Properties...17 Applications...17 Conjugate Antibodies MONOCLONAL ANTIBODY MARKET? AN OVERVIEW Introduction...18 Asia: A Lucrative Market...18 China?The Fastest Growing mab Market...181

4 Significant Growth in Therapeutic and Diagnostic Applications...19 Shift Towards Humanized and Fully Human Antibodies Advancements & Challenges in Antibody Production Processes...20 Future of mabs?smaller and Inexpensive to Produce...20 Structurally Modified Full-Size mabs?next Type of mabs to Hit the Market MAb Fragments...21 Competitive Scenario PRODUCT INTRODUCTIONS/INNOVATIONS AMSBIO Introduces Rabbit Monoclonal and Polyclonal Antibodies Portfolio...23 Immunocore Initiates Clinical Trials for IMCgp biom 閞 ieux Introduces VIDAS?EBV...24 PerkinElmer Introduces LANCE?Ultra Assay Products Radiometer Introduces NT-proBNP in AQT90 FLEX Immunoassay Analyzer Test Menu...25 Radiometer Introduces C-Reactive Protein in AQT90 FLEX Immunoassay Analyzer...25 Diagnostic Biosystems Introduces IVD Labeled Staining Reagents Range...25 Radiometer Adds bhcg Pregnancy Marker to AQT90 FLEX Immunoassay Analyzer Qualigen Introduces FastPack?hCG Immunoassay...26 Enterix Launches InSure?Quik F I T?Fecal Immunochemical Test...26 Amgen Introduces Vectibix...26 Trevigen Introduces Mouse Monoclonal Antibody RECENT INDUSTRY ACTIVITY

5 Rockland Immunochemicals Receives Grants from NIH...27 Bio-Rad Laboratories Acquires Diagnostic Businesses from Biotest...27 Beckman Coulter Takes Over Diagnostic Business of Olympus Roche Takes Over Genentech...28 GED Capital to Acquire Majority Stake in Diamedix...28 PerkinElmer Enters into Collaboration with BioLegend Abbott Inks Agreement with BG Medicine...29 Ortho Clinical Diagnostics Receives FDA Approval for VITROS?HBsAg Assay Athera Inks Agreements with Oxford Biosystems and Asbach Medical Products...30 CTI Acquires AVANT Immunotherapeutics...30 Clinical Genomics Enters into Global License Agreement with Quest Diagnostics Sigma-Aldrich Obtains Seppro Affinity Depletion Technology from GenWay Biotech Siemens to Merge with Siemens Healthcare Diagnostics...32 Merck Acquires Bangalore Genei...32 Commonwealth Biotechnologies to Purchase GL Biochem...32 Intercell Takes Over Iomai Thermo Fisher Scientific Takes Over Open Biosystems...33 Thermo Fisher Scientific Acquires Affinity BioReagents...33 Daiichi Sankyo Takes Over U3 Pharma IMUC Completes Molecular Antibody Technology Acquisition...34 EUSA Pharma to Take Over Cytogen Access Pharmaceuticals Acquires Somanta Pharmaceuticals...35

6 Genmab Enters into Antibody Research Collaboration with Pepscan...35 BTI Enters into an Agreement with Raven...35 Eusa Sells Antibody Research Business AVANIR Inks Definitive Agreement to Divest Anthrax Antibodies...36 CG Therapeutics and UoW Agree for Joint Monoclonal Antibody Program...36 SDI to Develop mabs for SAIC-F and NCI Morphotek and HMI in Licensing Agreement...37 Amgen Enters into Licensing Agreement with Kyowa Hakko Dyax and Sanofi-Aventis Sign Agreements...38 HGS Enters into Antibody Collaboration Agreement with Xencor Biogen Partners with Genentech and Roche for Development of GA Tecan Commences Operations at Refurbished Facility FOCUS ON SELECT PLAYERS Abbott Diagnostics (UK)...40 Advanced ImmunoChemical (US)...40 Beckman Coulter, Inc. (US) BioCat GmbH (Germany)...41 BIOTREND Chemikalien GmbH (Germany) Bio-Rad Laboratories, Inc. (US)...42 Dako (Denmark)...42 Life Technologies Corporation (US) Maine Biotechnology Services (US)...43 Meridian Life Science? Inc. (US)...43

7 Millipore Corporation (US) MitoSciences, Inc. (US)...44 MorphoSys AG (Germany) Randox Laboratories Ltd. (UK)...45 Roche Group (Switzerland) Rockland Immunochemicals (US) Sigma-Aldrich Co (US)...47 Trinity Biotech, PLC (Ireland) GLOBAL MARKET PERSPECTIVE...48 Table 4: World Recent Past, Current & Future Analysis for Immunochemicals by Geographic Region?US, Canada, Japan, Europe, China and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) Table 5: World Historic Review for Immunochemicals by Geographic Region?US, Canada, Japan, Europe, China and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart) Table 6: World 15-Year Perspective for Immunochemicals by Geographic Region?Percentage Breakdown of Annual Revenues for US, Canada, Japan, Europe, China and Rest of World Markets for Years 2003, 2010 & 2017 (includes corresponding Graph/Chart) Table 7: World Recent Past, Current & Future Analysis for Catalog Antibodies by Geographic Region?US, Canada, Japan, Europe, China and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) Table 8: World Historic Review for Catalog Antibodies by Geographic Region?US, Canada, Japan, Europe, China and Rest of World Markets Independently Analyzed with Annual Revenue

8 Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart) Table 9: World 15-Year Perspective for Catalog Antibodies by Geographic Region?Percentage Breakdown of Annual Revenues for US, Canada, Japan, Europe, China and Rest of World Markets for Years 2003, 2010 & 2017 (includes corresponding Graph/Chart) Table 10: World Recent Past, Current & Future Analysis for Custom Antibodies by Geographic Region?US, Canada, Japan, Europe, China and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) Table 11: World Historic Review for Custom Antibodies by Geographic Region?US, Canada, Japan, Europe, China and Rest of World Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart) Table 12: World 15-Year Perspective for Custom Antibodies by Geographic Region?Percentage Breakdown of Annual Revenues for US, Canada, Japan, Europe, China and Rest of World Markets for Years 2003, 2010 & 2017 (includes corresponding Graph/Chart) THE UNITED STATES Market Analysis...57 Table 13: US Recent Past, Current & Future Analysis for Immunochemicals by Type?Catalog Antibodies and Custom Antibodies Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) Table 14: US Historic Review for Immunochemicals by Type?Catalog Antibodies and Custom Antibodies Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)...58

9 Table 15: US 15-Year Perspective for Immunochemicals by Type?Percentage Breakdown of Annual Revenues for Catalog Antibodies and Custom Antibodies Markets for Years 2003, 2010 & CANADA Market Analysis...59 Table 16: Canadian Recent Past, Current & Future Analysis for Immunochemicals by Type?Catalog Antibodies and Custom Antibodies Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) Table 17: Canadian Historic Review for Immunochemicals by Type?Catalog Antibodies and Custom Antibodies Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)...60 Table 18: Canadian 15-Year Perspective for Immunochemicals by Type?Percentage Breakdown of Annual Revenues for Catalog Antibodies and Custom Antibodies Markets for Years 2003, 2010 & JAPAN Market Analysis...61 Table 19: Japanese Recent Past, Current & Future Analysis for Immunochemicals by Type?Catalog Antibodies and Custom Antibodies Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) Table 20: Japanese Historic Review for Immunochemicals by Type?Catalog Antibodies and Custom Antibodies Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)...62

10 Table 21: Japanese 15-Year Perspective for Immunochemicals by Type?Percentage Breakdown of Annual Revenues for Catalog Antibodies and Custom Antibodies Markets for Years 2003, 2010 & EUROPE Market Analysis...63 Table 22: European Recent Past, Current & Future Analysis for Immunochemicals by Type?Catalog Antibodies and Custom Antibodies Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) Table 23: European Historic Review for Immunochemicals by Type?Catalog Antibodies and Custom Antibodies Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)...64 Table 24: European 15-Year Perspective for Immunochemicals by Type?Percentage Breakdown of Annual Revenues for Catalog Antibodies and Custom Antibodies Markets for Years 2003, 2010 & CHINA A. Market Analysis...65 Outlook...65 A Rapidly Expanding mab Market...65 Strengths and Opportunities...65 Target-Specific Nature of Monoclonal Antibodies...65 Rising Incidence of Cancer & Age-Related Conditions: Potential Opportunity Manufacturing Advancements...66 Less Serious Side-Effects...66 Deep Pipeline...66 High Cost of mab Treatment in the EU and US Challenges Facing mab Market...67

11 High Manufacturing and Development Cost...67 Mode of Administration...67 Strong Competition...67 Expiration of Patents Immunogenicity...68 Regulatory Concerns...68 Financial Limitation...68 Low Reimbursement for mab B. Market Analytics...69 Table 25: Chinese Recent Past, Current & Future Analysis for Immunochemicals by Type?Catalog Antibodies and Custom Antibodies Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) Table 26: Chinese Historic Review for Immunochemicals by Type?Catalog Antibodies and Custom Antibodies Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)...70 Table 27: Chinese 15-Year Perspective for Immunochemicals by Type?Percentage Breakdown of Annual Revenues for Catalog Antibodies and Custom Antibodies Markets for Years 2003, 2010 & REST OF WORLD A. Market Analysis...71 Outlook...71 Asia Offers Enormous Opportunities for mab Market B. Market Analytics...72 Table 28: Rest of World Recent Past, Current & Future Analysis for Immunochemicals by Type?Catalog Antibodies and Custom Antibodies Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart)...721

12 Table 29: Rest of World Historic Review for Immunochemicals by Type?Catalog Antibodies and Custom Antibodies Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart)...73 Table 30: Rest of World 15-Year Perspective for Immunochemicals by Type?Percentage Breakdown of Annual Revenues for Catalog Antibodies and Custom Antibodies Markets for Years 2003, 2010 & COMPETITION344 Total Companies Profiled: 100 (including Divisions/Subsidiaries - 104) Region/Country Players The United States 66 Canada 2Japan 2Europe 31 France 4 Germany 6 The United Kingdom 8 Rest of Europe 13Asia-Pacific (Excluding Japan) 3 Click here to request a full table of contents and more details on this project.

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