High Throughput Screening (HTS) - Global Strategic Business Report

Transcription

1 Brochure More information from High Throughput Screening (HTS) - Global Strategic Business Report Description: This report analyzes the worldwide markets for High Throughput Screening (HTS) in US$ Million. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, and Rest of World. Annual estimates and forecasts are provided for the period 2009 through A six-year historic analysis is also provided for these markets. The report profiles 103 companies including many key and niche players such as Agilent Technologies Inc., Aurora Biomed Inc., Axxam SpA, Beckman Coulter, Inc., BioFocus DPI Ltd., Bio-Rad Laboratories, Inc., BMG LABTECH GmbH, Caliper Life Sciences, Inc., Corning Inc., DiscoveRx Corporation, EVOTEC BioSystems, ForteBio, Inc., Genedata AG, IntelliCyt Corporation, Life Technologies Corporation, Luminex Corporation, Molecular Devices Inc., PerkinElmer Inc., Roche Applied Sciences, Sigma-Aldrich Corporation, and Tecan Group Ltd. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based upon search engine sources in the public domain. Please note: Reports are sold as single-site single-user licenses. Electronic versions require hours as each copy is customized to the client with digital controls and custom watermarks. For information on site licence pricing please click on Enquire before buying. Contents: HIGH THROUGHPUT SCREENING (HTS) A GLOBAL STRATEGIC BUSINESS REPORT CONTENTS I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS Study Reliability and Reporting Limitations I-1 Disclaimers I-2 Data Interpretation & Reporting Level I-3 Quantitative Techniques & Analytics I-3 Product Definitions and Scope of Study I-3 II. Executive Summary 1. INDUSTRY OVERVIEW II-1 A Prelude II-1 Market Scenario II-1 How Far Has HTS Been Successful - A Case for and Against HTS II-2 Market Share Findings II-4 Table 1: World Liquid Handling Market (2010): Percentage Market Share Breakdown of Leading Players (includes corresponding Graph/Chart) II-4 Table 2: World Robotics Market (2010): Percentage Market Share Breakdown of Leading Players (includes corresponding Graph/Chart) II-4 Table 3: World Microplate Readers Market (2010): Percentage Market Share Breakdown of Leading Players (includes corresponding Graph/Chart) II-4 2. MARKET TRENDS & ISSUES II-5 HTS Adapts to Varied Lead Discovery Needs II-5

2 Compound Library and Target Selection Equally Important as Screening II-5 Cell-based Assays Represent the Primary Drug Discovery Tool in HTS Labs II-5 Smaller Companies and Academia Can Now Afford HTS II-5 Innovation in Screening Guarantees Success for Drug Discovery Programs II-6 HTS Advancements Promise a Bright Future for Stem Cell Research II-6 HTS in the Discovery of Drug for Alzheimer's disease II-7 Need for Stringent QA System to Keep Failures at Bay II-7 HTS Used in Identification of Kinase Inhibitors II-8 3. HTS TECHNOLOGY OVERVIEW II-9 What Drives HTS Labs towards New Technologies II-9 Major HTS Technologies II-9 Miniaturization II-9 HTS Miniaturization - Technology Developments II-10 IVC - A Miniaturized, Powerful HTS Technology II-10 Target Selection II-10 Label-free Technologies II-11 High-Content Screening (HCS) II-11 Innovations in Cell Culture II-11 Compound Libraries Expansion II-12 HTS - A Historical Perspective II PRODUCT OVERVIEW II-14 High Throughput Research (HTR) II-14 High Throughput - An Advanced Materials Research Approach II-14 Pharmaceutical Industry Leads the Way II-14 High Throughput Improves R&D Efficiency II-15 High Throughput Screening (HTS) II-15 The Equipment II-15 The Process II-16 HTS Robotics Supports Miniaturization II-17 HTS and uhts II-17 Functional and Non-Functional - Two Types of High Throughput Assays II-17 Setting up HTS Facilities - An Expensive Affair II-17 Important Components of HTS II-18 Few popular Chemical Libraries Used in Chemical Biology and Drug Discovery II-18 Table 4: Screening Throughput of Plates (includes corresponding Graph/Chart) II-18 Distinctions Between Bench Top and HTS Assays II HTS AND THE PHARMA INDUSTRY II-20 Impact of HTS on the Pharmaceutical Industry II-20 The Underlying Technology and Market Factors II-20 High Costs Involved with Sophistication - A Matter of Concern II-20 The HTS Business in Pharma Industry II-21 What Lies Ahead for HTS II-21 Hit and Lead Generation Strategies II-22 Different Stages in Hit and Lead Generation II-22 From Hit' to Lead' in HTS - A Complex Endeavor II DRUG DISCOVERY - AN OVERVIEW II-24 Drug Discovery - Definition II-24 Drug Discovery Process II-24 Drug Discovery Technologies II COMPUTER AIDED DRUG DISCOVERY (CADD) II-26 The Evolution of Computer Aided Drug Discovery (CADD) Processes II-26 CADD II-26

3 High Throughput Screening II-26 Virtual Screening II-27 Cloud Computing II PRODUCT INTRODUCTIONS/ INNOVATIONS II-28 Tox21 Launches Novel Robotic High Speed Screening System II-28 Life Technologies Introduces TaqMan OpenArray MicroRNA Panels II-28 Zyleris Introduces Screening Service for Drug Development II-28 Genosphere Introduces PepLib Custom Peptide Library Synthesis II-29 PerkinElmer Launches Lance Ultra camp Detection Kit for Profiling GPCRs II-29 PerkinElmer Introduces Epigenetics Detection Reagents for HTS of New Drug Candidates II-29 Agilent and BIOCIUS Introduce RF360 High Resolution System II-29 High Throughput Genomics and Luminex Introduce qbead Assay II-30 IntelliCyt Launches HTFCTM Screening System II-30 Luminex Corporation Launches FLEXMAP 3D, a High-Throughput System II-30 ForteBio Introduces Advanced Instruments for Life Science Research Industry II-31 BioTrove Introduces RapidFire 300 System for HTS of ADME Assays II-31 Sigma-Aldrich Launches PrecisioTM Kinases for High Througput Profiling II-32 Genedata Launches Genedata Screener 7.0 for HCS and HTS Analysis II-32 Roche Diagnostics Introduces RTCA HT Instrument II-32 Axxam and CyBio Introduce An Advanced Screening Station II-33 BMG LABTECH Unveils PHERAstar FS Reader for HTS Applications II-33 PharmaDiagnostics Unveils SoPRano CA1 Assay Kit II-33 SwitchGear Genomics Introduces High Throughput Screening Tools II-34 PerkinElmer Launches Upgraded MicroBeta 2 Microplate Counter Platform II-34 Intellicyt Launches Hypercyt Based Application, Flowtox Screening II RECENT INDUSTRY ACTIVITY II-35 Danaher Acquires Beckman Coulter II-35 Pall Acquires ForteBio II-35 Agilent Technologies Takes Over BIOCIUS Life Sciences II-35 EVOTEC BioSystems Takes Over Kinaxo Biotech II-35 Beckman Coulter and Vitrology Ink Biologics Testing Partnership Agreement II-36 Sigma Life Sciences and King's College Co-develop Target Identification Technology II-36 Lundbeck and Compound Focus Ink Compound Management Agreement II-36 Ligand to Divest Combinatorial Library and Certain Technologies to Venenum II-37 DiscoveRx Corp Acquires Kinase Screening Service Division of Ambit Biosciences II-37 Omeros Takes Over GPCR Assay Technology from Patabios II-37 TGS Collaborates with CarnaBio for Providing Drug Discovery Services II-37 AstraZeneca and MRC Technology Team Up for Drug Discovery, Share Compound Libraries II-38 Evotec and Biotech Partner for Small Molecule Modulator Identification II-38 ForteBio and Tecan Team Up to Provide Automated Label-Free Assays II-38 Protein Attachment and Blue Sky Biotech Ink Licensing Agreement II-39 BioAtla and Halozyme Team Up II-39 Jubilant Biosys and DiscoveRx Enter into an Co-marketing Agreement II-39 Plasticell Inks Partnership Agreement with Sigma-Aldrich II-40 Redpoint Bio Receives US Patent for its HTS Assay for TRPm5 Ion Channel II-40 Corning Takes Over Axygen BioScience II-40 ChanTest Takes over Applied Cell Sciences II-41

4 Nexus Biosystems Takes over Aurora Biotechnologies II-41 PerkinElmer Acquires Assets of GE Healthcare II-41 Cellectis and Laboratoires Servier Ink Licensing Agreement II-41 BioFocus to Integrate TET Technology in HTS Services II-42 BioFocus DPI Upgrades High-Throughput Screening Library II-42 Ono Pharmaceutical and Evotec Extend Research Collaboration II-42 Randox Labs and Seegene Enter into Agreement II-42 BioFocus DPI and Cellectricon Enter into Collaboration II-42 Evotec and DiscoveRx Ink Agreement to Support HTS Services II-43 Corning Announces a Major Milestone in Label- Free High Throughput Screening II FOCUS ON SELECT GLOBAL PLAYERS II-44 Agilent Technologies Inc. (US) II-44 Aurora Biomed Inc. (Canada) II-44 Axxam SpA (Italy) II-45 Beckman Coulter, Inc (US) II-45 BioFocus DPI Ltd (UK) II-46 Bio-Rad Laboratories, Inc. (US) II-46 BMG LABTECH GmbH (Germany) II-47 Caliper Life Sciences, Inc (US) II-47 Corning Inc (US) II-48 DiscoveRx Corporation (US) II-48 EVOTEC BioSystems (Germany) II-48 ForteBio (US) II-49 Genedata AG (Switzerland) II-49 IntelliCyt Corporation (US) II-49 Life Technologies Corporation (US) II-50 Luminex Corporation (US) II-50 Molecular Devices Inc. (US) II-50 PerkinElmer Inc (US) II-51 Roche Applied Sciences (Germany) II-51 Sigma-Aldrich Corporation (US) II-52 Tecan Group Ltd. (Switzerland) II GLOBAL MARKET PERSPECTIVE II-53 Table 5: World Recent Past, Current & Future Analysis for High Throughput Screening by Geographic Region - US, Canada, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Revenues in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) II-53 Table 6: World Historic Review for High Throughput Screening by Geographic Region - US, Canada, Japan, Europe and Rest of World Markets Independently Analyzed with Annual Revenues in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart) II-54 Table 7: World 15-Year Perspective for High Throughput Screening by Geographic Region - Percentage Breakdown of Dollar Revenues for US, Japan, Europe, and Rest of World Markets for Years 2003, 2011 & 2017 (includes corresponding Graph/Chart) II-55 III. MARKET 1. THE UNITED STATES III-1 A.Market Analysis III-1 Factors Driving Growth in the US HTS Market III-1 Government Providing a Helping Hand III-1 Product Introductions III-2 Strategic Corporate Developments III-5

5 Key Players III-8 B.Market Analytics III-16 Table 8: US Recent Past, Current & Future Analysis for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) III-16 Table 9: US Historic Review for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart) III CANADA III-18 A.Market Analysis III-18 Key Players III-18 B.Market Analytics III-19 Table 10: Canadian Recent Past, Current & Future Analysis for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) III-19 Table 11: Canadian Historic Review for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart) III JAPAN III-21 A.Market Analysis III-21 Strategic Corporate Development III-21 B.Market Analytics III-22 Table 12: Japanese Recent Past, Current & Future Analysis for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) III-22 Table 13: Japanese Historic Review for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart) III EUROPE III-24 A.Market Analysis III-24 Market Shifts Towards Maturity - Technological Innovations Come to the Rescue III-24 Product Introductions III-24 Strategic Corporate Developments III-26 Key Players III-28 B.Market Analytics III-31 Table 14: European Recent Past, Current & Future Analysis for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) III-31 Table 15: European Historic Review for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart) III REST OF WORLD III-33 A.Market Analysis III-33 Regional Overview III-33 HTS Gaining Ground in APAC III-33 China III-33

6 China Emerges as the Major Outsourcer for Drug Discovery III-33 Few Problem Areas Exist III-34 What Outsourcers Need to Look Forward to III-34 Life Sciences Market in China Continues to Thrive Despite Recession III-34 B.Market Analytics III-35 Table 16: Rest of World Recent Past, Current & Future Analysis for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2009 through 2017 (includes corresponding Graph/Chart) III-35 Table 17: Rest of World Historic Review for High Throughput Screening Market Independently Analyzed with Annual Revenues in US$ Million for Years 2003 through 2008 (includes corresponding Graph/Chart) III-36 IV. COMPETITIVE LANDSCAPE Total Companies Profiled: 103 (including Divisions/Subsidiaries - 107) Region/Country Players The United States 65 Canada 1 Japan 2 Europe 35 France 4 Germany 10 The United Kingdom 12 Italy 1 Rest of Europe 8 Asia-Pacific (Excluding Japan) Ordering: Order Online - Order by Fax - using the form below Order by Post - print the order form below and send to Research and Markets, Guinness Centre, Taylors Lane, Dublin 8, Ireland.

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