TECHNOLOGIES, PRODUCTS & SERVICES for MOLECULAR DIAGNOSTICS, MDx ABA 298

Save this PDF as:
 WORD  PNG  TXT  JPG

Size: px
Start display at page:

Download "TECHNOLOGIES, PRODUCTS & SERVICES for MOLECULAR DIAGNOSTICS, MDx ABA 298"

Transcription

1 DIAGNOSTICS BUSINESS ANALYSIS SERIES: TECHNOLOGIES, PRODUCTS & SERVICES for MOLECULAR DIAGNOSTICS, MDx ABA 298 By ADAMS BUSINESS ASSOCIATES MAY May 2014 ABA 298 1

2 Technologies, Products & Services for Molecular Diagnostics, MDx, May 2014 CONTENTS LIST 1. Introduction & Purpose for Business Analysis of Molecular Diagnostics 1 2. Technology Procedures for Molecular Diagnostics Technology Overview Accessories for DNA Analysis & MDx Technologies for Molecular Diagnostics Descriptions DNA Probes for DNA Analysis & MDx Amplification Methods for DNA Analysis & MDx DNA Sequencing for DNA Analysis & MDx Custom Services for DNA Analysis & MDx BioInformatics for DNA Analysis & MDx Targets for DNA Analysis & Molecular Diagnostics Single Nucleotide Polymorphisms, SNPs RNA Interference, RNAi & sirna & MicroRNA, mirna Whole Genome Targeting or Genome Wide Association Studies, GWAS Epigenetics DNA methylation, Histone Modification Applications of DNA Analysis & Molecular Diagnostics Application Overview Clinical Diagnostics Genomics & Inherited Disease Diagnostics Drug Discovery & Toxicology Personalised Medicine & Companion Diagnostics POCT and Molecular Diagnostics Cytogenetics and Molecular Diagnostics Non-Clinical Applications of Molecular Diagnostics Challenges for Technology & Applications for Molecular Diagnostics 106 2

3 4. Regulatory, Reimbursement & Ethical Impact for Molecular Diagnostics Regulatory Dynamics & Impact Reimbursement Impact for Molecular Diagnostics Ethical Impact for Molecular Diagnostics Market Segments & Quantification for Molecular Diagnostics Total Market & Sector Dynamics Application Markets for Molecular Diagnostic Test Company Profiles & Status for Molecular Diagnostics, 2013/ Company Profile Introduction Established Diagnostic Companies Focussed Molecular Diagnostic Companies Molecular Diagnostic Service Laboratories Life Science Research Molecular Diagnostic Companies Strategic Marketing Implications for Molecular Diagnostics Marketing Philosophy Technology Status Marketing Tools & Generic Strategic Marketing Strategies Applied to MDx 191 3

4 FIGURES 1. Introduction & Purpose for Business Analysis of Molecular Diagnostics 1 Figure Reports for ABA Global Library for Life Science Research & Diagnostics 1 Figure ABA Global Library for Life Science Research Reports Second Edition Figure Biotechnology as a Sector or an Enabling Technology, Figure Basic Features of the Technology S-Curve 6 Figure Technology S-Curve for the IVD Sector in 2013/14 6 Figure Biological Cascade for Life Sciences 9 Figure Healthcare Dynamics for IVDs, Figure Healthcare Dynamics for in vitro Diagnostics & Medical Devices, Figure Genomics and Proteomics Links for in vitro Diagnostics Research 13 Figure Genomic Research & Drug Discovery for MDx Analysis, Technology Procedures for Molecular Diagnostics 17 Figure DNA Analysis Technologies Used in Figure DNA Analysis Product Listings, Figure Microarray Systems & Products, Figure Thermal Cycler Key Features & Importance Rating, Figure DNA Analysis & MDx Accessories Vendor Listing, Figure DNA Analysis Product Listings, Figure DNA Probe Products & Accessory Supplier Examples, Figure DNA Amplification Technology 36 Figure DNA Amplification Technology for Diagnostic Applications 38 Figure Molecular Diagnostics Leading Amplification Technologies, Figure Amplification Method Comparison, Figure qpcr Amplification Systems, Figure Molecular Diagnostics Technology Uses in Pathway Analysis Figure DNA Sequencing Technology Commercial Suppliers Figure Genomics & DNA Analysis & MDx Service Provider Companies, Figure Genomics & Proteomics Bioinformatics Products & Suppliers, Figure Technologies for SNP Determinations 1. MALDI-TOF Mass Spectroscopy 55 Figure Technologies for SNP Determinations 2. Triplex Forming Probes 55 Figure Possible SNP Applications in Gene Analysis 55 Figure Commercial SNP Platforms & Products, Figure microrna Profiling Service Companies, Figure Companies Providing microrna Products,

5 3. Applications of DNA Analysis & Molecular Diagnostics 67 Figure Proposed Major Applications for Molecular Diagnostics as of Figure Technology Application Status for MDx Applications, Figure Technology & Application Status for Molecular Diagnostics, Figure Microarrays & DNA Analysis Applications 73 Figure Cancer Diagnostics Molecular Diagnostics Applications 75 Figure Infectious Disease Molecular Diagnostic Applications 76 Figure Example Genomic Analysis, microrna & Epigenetic Products & Applications 80 Figure Example Next Generation Sequencing Products, Figure MDx Applications & Focus Areas for Drug Discovery, Figure MDx Applications in the Drug Discovery Process, Figure Examples of Major Drug Response Rates 91 Figure Early Examples & Development Diagnostics 93 Figure Benefits & Hurdles for MDx Companion Diagnostics, CDx 94 Figure Potential Impact of Synthetic Biology Involving Molecular Diagnostics Regulatory, Reimbursement & Ethical Impact for Molecular Diagnostics 109 Figure European IVD-MMD Product Classifications, 2013/ Figure Summary of Class Approval Procedures for CE Mark Assignment Market Quantification & Dynamics for Molecular Diagnostics 130 Figure Global Molecular Diagnostics Market Figures & Projections, Figure Molecular Diagnostic Tests & Products from LabMedica May Figure Molecular Diagnostic Test Regional IVD Market Distribution, 2004 & Figure IVD and Molecular Diagnostic Tests Regional Market Distribution, 2013/ Figure Molecular Diagnostic Test Segment Distribution, 2013/ Figure Molecular Diagnostic Test Segment Distribution in Europe, 2013/ Figure Molecular Diagnostic Global Technology Distribution, 2013/ Figure Clinical & Genetic Testing Molecular Diagnostic Product Group Markets, Figure Genetic Testing Molecular Diagnostic Product Group Markets, Figure Regional Clinical Applications of Molecular Diagnostic Product Groups, Figure Regional Clinical Applications of Molecular Diagnostic Product Groups, Figure Clinical Diagnostics Approved in the USA, Figure European Infectious Disease Clinical Diagnostics Markets by Country, Figure Potential Areas for Future Molecular Diagnostics Clinical Application Areas 149 5

6 Figure Research Areas for Molecular Diagnostics Development & Applications, Figure Regional Research & Clinical Research MDx Product Groups, Figure Non-Clinical Molecular Diagnostic Application Markets, Company Profiles & Status for Molecular Diagnostics, 2013/ Figure Company Profile Summary Abbott Diagnostics 155 Figure Company Profile Summary Becton Dickinson 156 Figure Company Profile Summary biomerieux 156 Figure Company Profile Summary Bio Rad Laboratories 157 Figure Company Profile Summary Danaher [Beckman Coulter] 157 Figure Company Profile Summary Grifols 158 Figure Company Profile Summary Roche Molecular Diagnostics 159 Figure Company Profile Summary Siemens 160 Figure Broad Based Diagnostic Company Business Shares, Figure Company Profile Summary Cepheid 162 Figure Company Profile Summary Agilent [Dako, etc] 163 Figure Company Profile Summary Hologic [Gen Probe & Third Wave Technologies] 164 Figure Company Profile Summary Qiagen 165 Figure Company Profile Summary Enigma Diagnostics 166 Figure Molecular Biology Based MDx Company Market Positions, Figure Company Profile Summary Myriad Genetics 168 Figure Company Profile Summary Locus Development Inc. [Genomic Health] 169 Figure Molecular Diagnostic Services for MDx Products, Figure Company Profile Summary Illumina 172 Figure Company Profile Summary Sequenom 173 Figure Company Profile Summary Affymetrix 173 Figure Company Profile Summary Fluidigm 174 Figure Life Science Research Suppliers of MDx Products, Figure Overview of Commercial Molecular Diagnostic Companies, Strategic Marketing Implications for Molecular Diagnostics 186 Figure Typical Key Elements in MDx Basis of Competition Analysis 187 Figure S-Curve Technology Analysis for Molecular Diagnostics,

PERSONALISED MEDICINE & POINT-of-CARE TESTS, POCT ABA 310

PERSONALISED MEDICINE & POINT-of-CARE TESTS, POCT ABA 310 DIAGNOSTICS BUSINESS ANALYSIS SERIES: PERSONALISED MEDICINE & POINT-of-CARE TESTS, POCT ABA 310 By ADAMS BUSINESS ASSOCIATES April 2014. April 2014 ABA 310 1 Personalised Medicine & Point-of-Care Tests,

More information

TECHNOLOGY PATENTS IN THE (CONTINUED)... 16

TECHNOLOGY PATENTS IN THE (CONTINUED)... 16 CHAPTER ONE: INTRODUCTION... 1 STUDY GOALS AND OBJECTIVES... 1 REASONS FOR DOING THIS STUDY... 1 SCOPE AND FORMAT... 1 METHODOLOGY AND INFORMATION SOURCES... 2 INTENDED AUDIENCE... 2 ANALYST CREDENTIALS...

More information

POLYMERASE CHAIN REACTION (PCR) TECHNOLOGIES AND GLOBAL MARKETS

POLYMERASE CHAIN REACTION (PCR) TECHNOLOGIES AND GLOBAL MARKETS POLYMERASE CHAIN REACTION (PCR) TECHNOLOGIES AND GLOBAL MARKETS BIO087C August 2016 Shalini Shahani Dewan Project Analyst ISBN: 1-62296-333-4 BCC Research 49 Walnut Park, Building 2 Wellesley, MA 02481

More information

INTERNATIONAL CONFERENCE ON HARMONISATION OF TECHNICAL REQUIREMENTS FOR REGISTRATION OF PHARMACEUTICALS FOR HUMAN USE E15

INTERNATIONAL CONFERENCE ON HARMONISATION OF TECHNICAL REQUIREMENTS FOR REGISTRATION OF PHARMACEUTICALS FOR HUMAN USE E15 INTERNATIONAL CONFERENCE ON HARMONISATION OF TECHNICAL REQUIREMENTS FOR REGISTRATION OF PHARMACEUTICALS FOR HUMAN USE ICH HARMONISED TRIPARTITE GUIDELINE DEFINITIONS FOR GENOMIC BIOMARKERS, PHARMACOGENOMICS,

More information

CHAPTER FOUR: NEXT GENERATION CANCER DIAGNOSTIC TECHNOLOGIES... 16

CHAPTER FOUR: NEXT GENERATION CANCER DIAGNOSTIC TECHNOLOGIES... 16 CHAPTER ONE: INTRODUCTION... 1 STUDY GOALS AND OBJECTIVES... 1 REASONS FOR DOING THE STUDY... 1 INTENDED AUDIENCE... 2 SCOPE OF REPORT... 2 METHODOLOGY... 3 INFORMATION SOURCES... 3 RELATED BCC REPORTS...

More information

DNA Sequencing and PCR Markets

DNA Sequencing and PCR Markets Brochure More information from http://www.researchandmarkets.com/reports/41864/ DNA Sequencing and PCR Markets Description: DNA sequencing and polymerase chain reaction (PCR) are two major technology platforms

More information

Next Generation Sequencing Informatics Markets

Next Generation Sequencing Informatics Markets Next Generation Sequencing Informatics Markets Greg Caressi SVP Healthcare & Life Sciences November, 2014 Personalization, Communication, Decentralization, Collaboration From... One Size Fits All APPROACH...To

More information

(SAMPLE COPY, NOT FOR RESALE)

(SAMPLE COPY, NOT FOR RESALE) TriMark Publications May 2016 Volume: TMRMDIDT16-0501 MOLECULAR DIAGNOSTICS IN INFECTIOUS DISEASE TESTING (SAMPLE COPY, NOT FOR RESALE) Trends, Industry Participants, Product Overviews and Market Drivers

More information

Global In-vitro Diagnostics Instruments Market

Global In-vitro Diagnostics Instruments Market Global In-vitro Diagnostics Instruments Market 2016-2020 No of Pages 101 Publishing Date - November 14, 2016 Browse detailed TOC, Tables, Figures, Charts in Global In-vitro Diagnostics Instruments Market

More information

SOLUTIONS FOR NEXT-GENERATION SEQUENCING

SOLUTIONS FOR NEXT-GENERATION SEQUENCING SOLUTIONS FOR NEXT-GENERATION SEQUENCING GENOMICS CELL BIOLOGY PROTEOMICS AUTOMATION enabling next-generation research From Samples To Publication, Millennium Science Enables Your Next-Gen Sequencing Workflow

More information

Global Digital PCR Market Research, PCR Reaction Market Insights, Opportunity, Analysis, Market Shares And Forecast

Global Digital PCR Market Research, PCR Reaction Market Insights, Opportunity, Analysis, Market Shares And Forecast Brochure More information from http://www.researchandmarkets.com/reports/3050459/ Global Digital PCR Market Research, PCR Reaction Market Insights, Opportunity, Analysis, Market Shares And Forecast 2016-2022

More information

The Molecular Diagnostic Market and development of personalized molecular tests

The Molecular Diagnostic Market and development of personalized molecular tests The Molecular Diagnostic Market and development of personalized molecular tests Dr. Iris Simon Sr. Director Research & Development, Agendia NV, Amsterdam NL and Irvine CA Agendia - Who are we Molecular

More information

Innovative genetics research and biomarker solutions to advance molecular medicine. Corporate Overview

Innovative genetics research and biomarker solutions to advance molecular medicine. Corporate Overview Innovative genetics research and biomarker solutions to advance molecular medicine Corporate Overview April 2013 1 Oxford Gene Technology (OGT) Advancing molecular medicine Well-established private genomics

More information

Cancer Personalized Medicine

Cancer Personalized Medicine GENReports: Market & Tech Analysis Cancer Personalized Medicine > Enal Razvi, Ph.D. Biotechnology Analyst, Managing Director SELECTBIO US enal@selectbio.us Topics Addressed In this GEN Market & Tech Analysis

More information

Life Sciences Tools Industry Background

Life Sciences Tools Industry Background Life Sciences Tools Industry Background October 2003 This presentation contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking

More information

Molecular diagnostics is now used for a wide range of applications, including:

Molecular diagnostics is now used for a wide range of applications, including: Molecular Diagnostics: A Dynamic and Rapidly Broadening Market Molecular diagnostics is now used for a wide range of applications, including: Human clinical molecular diagnostic testing Veterinary molecular

More information

DNA Sequencing and Personalised Medicine

DNA Sequencing and Personalised Medicine DNA Sequencing and Personalised Medicine Mick Watson Director of ARK-Genomics The Roslin Institute PERSONALISED MEDICINE What is personalised medicine? Personalized Medicine refers to the tailoring of

More information

Russia Genetic Testing Market Outlook to 2021

Russia Genetic Testing Market Outlook to 2021 Russia Genetic Testing Market Outlook to 2021 GlobalData s new report, Russia Genetic Testing Market Outlook to 2021, provides key market data on the Russia Genetic Testing market. The report provides

More information

Core Facility Genomics

Core Facility Genomics Core Facility Genomics versatile genome or transcriptome analyses based on quantifiable highthroughput data ascertainment 1 Topics Collaboration with Harald Binder and Clemens Kreutz Project: Microarray

More information

Genetic testing. The difference diagnostics can make. The British In Vitro Diagnostics Association

Genetic testing. The difference diagnostics can make. The British In Vitro Diagnostics Association 6 Genetic testing The difference diagnostics can make The British In Vitro Diagnostics Association Genetic INTRODUCTION testing The Department of Health published Our Inheritance, Our Future - Realising

More information

AdvaMedDx.org 4 EDMA and its Market Intelligence Activities EDMA Statistics Evolution Up to the late 80 s no harmonized IVD market statistics National trade associations in Europe established their own

More information

School of Nursing. Presented by Yvette Conley, PhD

School of Nursing. Presented by Yvette Conley, PhD Presented by Yvette Conley, PhD What we will cover during this webcast: Briefly discuss the approaches introduced in the paper: Genome Sequencing Genome Wide Association Studies Epigenomics Gene Expression

More information

QIAGEN Management Buyout Synthetic DNA Business Unit Conference Call

QIAGEN Management Buyout Synthetic DNA Business Unit Conference Call QIAGEN Management Buyout Synthetic DNA Business Unit Conference Call July 1, 2004 Welcome to QIAGEN s Conference Call Second Management Quarter Buyout and Synthetic Half Year DNA 2003 Business Conference

More information

The National Institute of Genomic Medicine (INMEGEN) was

The National Institute of Genomic Medicine (INMEGEN) was Genome is...... the complete set of genetic information contained within all of the chromosomes of an organism. It defines the particular phenotype of an individual. What is Genomics? The study of the

More information

Nature of Genetic Material. Nature of Genetic Material

Nature of Genetic Material. Nature of Genetic Material Core Category Nature of Genetic Material Nature of Genetic Material Core Concepts in Genetics (in bold)/example Learning Objectives How is DNA organized? Describe the types of DNA regions that do not encode

More information

Performance Driven Media. 35 Anniversary! Leading The Way in Life Science Technologies. Genetic Engineering & Biotechnology News

Performance Driven Media. 35 Anniversary! Leading The Way in Life Science Technologies. Genetic Engineering & Biotechnology News Performance Driven Media 35 Anniversary! th Leading The Way in Life Science Technologies Genetic Engineering & Biotechnology News January 1 Reservation: 11/30/15 Material: 12/7/15 l Genome Editing l High-Content

More information

WG5: Informatics. Martin Dugas, Jaakko Hollmen. European Genomics and Epigenomics Study on MDS and AML

WG5: Informatics. Martin Dugas, Jaakko Hollmen. European Genomics and Epigenomics Study on MDS and AML WG5: Informatics Martin Dugas, Jaakko Hollmen EuGESMA European Genomics and Epigenomics Study on MDS and AML Presentations from WG5 members Hans Ulrich Klein Detection of Fusion Genes by Targeted Roche

More information

Market Research at the NCBiotech Library

Market Research at the NCBiotech Library Market Research at the NCBiotech Library The library's subscriptions include selected reports from BCC Research and Kalorama Information. Abstracts and Tables of Contents are freely available online from

More information

Roche Diagnostics Driving Personalized Healthcare

Roche Diagnostics Driving Personalized Healthcare r his presentation contains certain forward-looking statements. hese forward-looking statements may be identified by words such as believes, expects, anticipates, projects, intends, should, seeks, estimates,

More information

Biotechnology and Life Science Marketing Services Mailing List and Data Card Order Form

Biotechnology and Life Science Marketing Services Mailing List and Data Card Order Form C H I Cambridge Healthtech Institute s Biotechnology and Life Science Marketing Services Mailing List and Data Card Order Form Over 800,000 names segmented by scientific interest Featuring U.S and International

More information

G E N OM I C S S E RV I C ES

G E N OM I C S S E RV I C ES GENOMICS SERVICES THE NEW YORK GENOME CENTER NYGC is an independent non-profit implementing advanced genomic research to improve diagnosis and treatment of serious diseases. capabilities. N E X T- G E

More information

REAL-TIME PCR KITS FOR DIAGNOSIS

REAL-TIME PCR KITS FOR DIAGNOSIS REAL-TIME PCR KITS FOR DIAGNOSIS 483 Reproducible, Sensitive and Precise Analysis Real Time PCR (qpcr) has revolutionized biological and medical sciences by providing quantitative detection of specific

More information

Molecular Diagnostics in Cancer Testing

Molecular Diagnostics in Cancer Testing Product Sheet More information at http://www.biomarketgroup.com/market-research-report/molecular-diagnostics-in-cancertesting.html Molecular Diagnostics in Cancer Testing Published: 2015-AUG-01 Pages:

More information

Synthetic Biology Market. Future Market Insights. Share, Global Trends, Analysis, Research, Report, Opportunities, Segmentation and Forecast, 2016

Synthetic Biology Market. Future Market Insights. Share, Global Trends, Analysis, Research, Report, Opportunities, Segmentation and Forecast, 2016 Synthetic Biology Market Share, Global Trends, Analysis,, Report, Opportunities, Segmentation and Forecast, 2016 Future Market Insights www.futuremarketinsights.com sales@futuremarketinsights.com Future

More information

Microarray Technology

Microarray Technology Microarrays And Functional Genomics CPSC265 Matt Hudson Microarray Technology Relatively young technology Usually used like a Northern blot can determine the amount of mrna for a particular gene Except

More information

Introduction To Epigenetic Regulation: How Can The Epigenomics Core Services Help Your Research? Maria (Ken) Figueroa, M.D. Core Scientific Director

Introduction To Epigenetic Regulation: How Can The Epigenomics Core Services Help Your Research? Maria (Ken) Figueroa, M.D. Core Scientific Director Introduction To Epigenetic Regulation: How Can The Epigenomics Core Services Help Your Research? Maria (Ken) Figueroa, M.D. Core Scientific Director Gene expression depends upon multiple factors Gene Transcription

More information

Targos Efficient Reliable Flexible

Targos Efficient Reliable Flexible Targos Efficient Reliable Flexible In Business for Personalized Healthcare Targos Molecular Pathology Clinical Biomarker Services Targos Advance Training & Consulting Targos Development Biomarker R&D 1

More information

The Human Genome Project

The Human Genome Project The Human Genome Project Brief History of the Human Genome Project Physical Chromosome Maps Genetic (or Linkage) Maps DNA Markers Sequencing and Annotating Genomic DNA What Have We learned from the HGP?

More information

Regulatory Issues in Genetic Testing and Targeted Drug Development

Regulatory Issues in Genetic Testing and Targeted Drug Development Regulatory Issues in Genetic Testing and Targeted Drug Development Janet Woodcock, M.D. Deputy Commissioner for Operations Food and Drug Administration October 12, 2006 Genetic and Genomic Tests are Types

More information

HUMAN GENETIC TESTING PATENTS : ELIGIBILITY AND ENFORCEMENT

HUMAN GENETIC TESTING PATENTS : ELIGIBILITY AND ENFORCEMENT HUMAN GENETIC TESTING PATENTS : ELIGIBILITY AND ENFORCEMENT FRENCH APPROACH DENISE HIRSCH HEAD OF IP THE ENVIRONNENT Patentability of living organism was a public debate in France focusing on ethical issues

More information

A Cost Effective Way to De Risk Biomarker Clinical Trials: Early Development Considerations

A Cost Effective Way to De Risk Biomarker Clinical Trials: Early Development Considerations A Cost Effective Way to De Risk Biomarker Clinical Trials: Early Development Considerations Ce3, Inc. and Insight Genetics, Inc. Oncology Forum July 15, 2015 Agenda Introductions Definitions Regulations

More information

The Business Model for Test Development

The Business Model for Test Development The Business Model for Test Development Perspective from a reference laboratory National Cancer Policy Forum Workshop: Policy Issues in the Development and Adoption of Molecularly Targeted Therapies for

More information

Course outline. Code: BIM202 Title: Genes in Health and Disease

Course outline. Code: BIM202 Title: Genes in Health and Disease Course outline Code: BIM202 Title: Genes in Health and Disease Faculty of: Science, Health, Education and Engineering Teaching Session: Semester 1 Year: 2015 Course Coordinator: Dr Anna Kuballa Tel: (07)

More information

12/6/12. Dr. Sanjeeva Srivastava. IIT Bombay 2. Genomics Transcriptomics Why proteomics? Proteomics Course NPTEL

12/6/12. Dr. Sanjeeva Srivastava. IIT Bombay 2. Genomics Transcriptomics Why proteomics? Proteomics Course NPTEL Dr. Sanjeeva Srivastava IIT Bombay Genomics Transcriptomics Why proteomics? IIT Bombay 2 1 IIT Bombay 3 Genome: The entire sequence of an organism s hereditary information, including both coding and non-coding

More information

The HEE Genomics Programme

The HEE Genomics Programme The HEE Genomics Programme Genomics Advisory Board Chaired by Ian Cumming Membership from all relevant stakeholders PHE and PHG Genomics England NHSE Patient and public Royal Colleges Educational leaders,

More information

AGILENT S BIOINFORMATICS ANALYSIS SOFTWARE

AGILENT S BIOINFORMATICS ANALYSIS SOFTWARE ACCELERATING PROGRESS IS IN OUR GENES AGILENT S BIOINFORMATICS ANALYSIS SOFTWARE GENESPRING GENE EXPRESSION (GX) MASS PROFILER PROFESSIONAL (MPP) PATHWAY ARCHITECT (PA) See Deeper. Reach Further. BIOINFORMATICS

More information

How many of you have checked out the web site on protein-dna interactions?

How many of you have checked out the web site on protein-dna interactions? How many of you have checked out the web site on protein-dna interactions? Example of an approximately 40,000 probe spotted oligo microarray with enlarged inset to show detail. Find and be ready to discuss

More information

Name Class Date. KEY CONCEPT Mutations are changes in DNA that may or may not affect phenotype. frameshift mutation

Name Class Date. KEY CONCEPT Mutations are changes in DNA that may or may not affect phenotype. frameshift mutation Unit 7 Study Guide Section 8.7: Mutations KEY CONCEPT Mutations are changes in DNA that may or may not affect phenotype. VOCABULARY mutation point mutation frameshift mutation mutagen MAIN IDEA: Some mutations

More information

BIOMARKERS & MOLECULAR TUMOUR CLASSIFICATION FOR NON-GENOTOXIC CARCINOGENESIS

BIOMARKERS & MOLECULAR TUMOUR CLASSIFICATION FOR NON-GENOTOXIC CARCINOGENESIS MARCAR BIOMARKERS & MOLECULAR TUMOUR CLASSIFICATION FOR NON-GENOTOXIC CARCINOGENESIS What patients need What Europe needs Improved drug safety Increased efficiency of drug development Earlier detection

More information

Human Genome Organization: An Update. Genome Organization: An Update

Human Genome Organization: An Update. Genome Organization: An Update Human Genome Organization: An Update Genome Organization: An Update Highlights of Human Genome Project Timetable Proposed in 1990 as 3 billion dollar joint venture between DOE and NIH with 15 year completion

More information

Molecular Diagnostics Market Trends and Outlook Mark D. Hughes, Vice President Enterprise Analysis Corporation

Molecular Diagnostics Market Trends and Outlook Mark D. Hughes, Vice President Enterprise Analysis Corporation Molecular Diagnostics Market Trends and Outlook Mark D. Hughes, Vice President Enterprise Analysis Corporation What this report contains: Overview of current global market size and forecast Examination

More information

Next Generation Sequencing: Technology, Mapping, and Analysis

Next Generation Sequencing: Technology, Mapping, and Analysis Next Generation Sequencing: Technology, Mapping, and Analysis Gary Benson Computer Science, Biology, Bioinformatics Boston University gbenson@bu.edu http://tandem.bu.edu/ The Human Genome Project took

More information

FACULTY OF MEDICAL SCIENCE

FACULTY OF MEDICAL SCIENCE Doctor of Philosophy Program in Microbiology FACULTY OF MEDICAL SCIENCE Naresuan University 171 Doctor of Philosophy Program in Microbiology The time is critical now for graduate education and research

More information

An Introduction to Genomics and SAS Scientific Discovery Solutions

An Introduction to Genomics and SAS Scientific Discovery Solutions An Introduction to Genomics and SAS Scientific Discovery Solutions Dr Karen M Miller Product Manager Bioinformatics SAS EMEA 16.06.03 Copyright 2003, SAS Institute Inc. All rights reserved. 1 Overview!

More information

ONE WORKFLOW. ONE PARTNER. ACTIONABLE INSIGHTS. Sample to Insight

ONE WORKFLOW. ONE PARTNER. ACTIONABLE INSIGHTS. Sample to Insight ONE WORKFLOW. ONE PARTNER. ACTIONABLE INSIGHTS. Sample to Insight (NGS) Nucleic Acid More actionable data and insights in one go. More confidence at one glance. A small step for you, a giant leap for your

More information

Worldwide Markets and Emerging Technologies for Point-of-Care Testing, 2013-2019. February 2015

Worldwide Markets and Emerging Technologies for Point-of-Care Testing, 2013-2019. February 2015 Worldwide Markets and Emerging Technologies for Point-of-Care Testing, 2013-2019 February 2015 INTELAB CORPORATION MARKET AND TECHNOLOGY REPORTS Report 530 Copyright 2015 Worldwide Markets and Emerging

More information

Recombinant DNA and Biotechnology

Recombinant DNA and Biotechnology Recombinant DNA and Biotechnology Chapter 18 Lecture Objectives What Is Recombinant DNA? How Are New Genes Inserted into Cells? What Sources of DNA Are Used in Cloning? What Other Tools Are Used to Study

More information

In vitro Device Regulation

In vitro Device Regulation In vitro Device Regulation Molecular Pathologists Reagent (Analyte) Manufacturers High Complexity Clinical Labs Commercial Academic in Vitro Diagnostics Manufacturers Drug Developers large & small 2 States

More information

MicroRNA: An Insight to mirna-based Microarrays, Diagnostics and Therapeutics

MicroRNA: An Insight to mirna-based Microarrays, Diagnostics and Therapeutics 1 MicroRNA: An Insight to mirna-based Microarrays, Diagnostics and Therapeutics Available Now! Newly Released Report, with expanded focus, coverage and primary data! New to Insight Pharma Reports is: MicroRNA:

More information

A Primer of Genome Science THIRD

A Primer of Genome Science THIRD A Primer of Genome Science THIRD EDITION GREG GIBSON-SPENCER V. MUSE North Carolina State University Sinauer Associates, Inc. Publishers Sunderland, Massachusetts USA Contents Preface xi 1 Genome Projects:

More information

Written test: Analysis of data from high-throughput molecular biology experiments BB2490 (BIO) or DD2399 (CSC)

Written test: Analysis of data from high-throughput molecular biology experiments BB2490 (BIO) or DD2399 (CSC) Written test: Analysis of data from high-throughput molecular biology experiments BB2490 (BIO) or DD2399 (CSC) Name: Pnr: Wednesday the 18th of February, 13.00-15.00, Albanova FB52 Instructions: The test

More information

A leader in the development and application of information technology to prevent and treat disease.

A leader in the development and application of information technology to prevent and treat disease. A leader in the development and application of information technology to prevent and treat disease. About MOLECULAR HEALTH Molecular Health was founded in 2004 with the vision of changing healthcare. Today

More information

FOR TEXTILES. o Kuchipudi-I] textiles. Outdoor Activity Based Courses. Camp

FOR TEXTILES. o Kuchipudi-I] textiles. Outdoor Activity Based Courses. Camp SEMESTER I Basic Sciences Courses o General Chemistry o Biology for Engineers o Fundamentals of Mathematics o Applied Physics-I for Life Science Behavioural Science o Understanding Self for Effectiveness

More information

For More information http://industry-experts.com/verticals/biotechnology/bioinformatics-a-global-marketoverview.html

For More information http://industry-experts.com/verticals/biotechnology/bioinformatics-a-global-marketoverview.html Summary At the beginning of the genomic revolution, Bioinformatics was applied in creating and maintaining a database that stored biological information, such as nucleotide and amino acid sequences. Development

More information

HealthBIO in Helsinki Region 2008 BioSA Workshops in South Africa, 31.3 2.4.2008

HealthBIO in Helsinki Region 2008 BioSA Workshops in South Africa, 31.3 2.4.2008 HealthBIO in Helsinki Region 2008 BioSA Workshops in South Africa, 31.3 2.4.2008 Riikka Paasikivi Program Director Culminatum Ltd Oy Helsinki, Finland Helsinki Region Over 1.2 million inhabitants (population

More information

Top Peer Reviewed Journals Molecular Biology & Genetics

Top Peer Reviewed Journals Molecular Biology & Genetics Top Peer Reviewed Journals Molecular Biology & Genetics Presented to Iowa State University Presented by Thomson Reuters Molecular Biology & Genetics The subject discipline for Molecular Biology & Genetics

More information

ITT Advanced Medical Technologies (Ileri Tip Teknolojileri)

ITT Advanced Medical Technologies (Ileri Tip Teknolojileri) ITT Advanced Medical Technologies (Ileri Tip Teknolojileri) ITT Advanced Medical Technologies (Ileri Tip Teknolojileri) is a biotechnology company (SME) established in Turkey. Its activity area is research,

More information

Cell Discovery 360: Explore more possibilities.

Cell Discovery 360: Explore more possibilities. Cell Discovery 360: Explore more possibilities. Flexible solutions for the BioPharma laboratory Blood Banking Capillary Electrophoresis Centrifugation Flow Cytometry Genomics Lab Automation Lab Tools Particle

More information

SAMPLE. ik Accession Number: ik09- GD0XXXXX

SAMPLE. ik Accession Number: ik09- GD0XXXXX Patient Name: XXXXXXXXX Gender: X Date of Birth: XX/XX/XXXX Specimen Type: 10 unstained slides Submitters Name: XXXXXXXX, MD Submitters Institution: XXXXXXXX ik Accession Number: ik09- GD0XXXXX Date specimen

More information

SEQUENCING. From Sample to Sequence-Ready

SEQUENCING. From Sample to Sequence-Ready SEQUENCING From Sample to Sequence-Ready ACCESS ARRAY SYSTEM HIGH-QUALITY LIBRARIES, NOT ONCE, BUT EVERY TIME The highest-quality amplicons more sensitive, accurate, and specific Full support for all major

More information

Summary of Discussion on Non-clinical Pharmacology Studies on Anticancer Drugs

Summary of Discussion on Non-clinical Pharmacology Studies on Anticancer Drugs Provisional Translation (as of January 27, 2014)* November 15, 2013 Pharmaceuticals and Bio-products Subcommittees, Science Board Summary of Discussion on Non-clinical Pharmacology Studies on Anticancer

More information

Integration of Genetic and Familial Data into. Electronic Medical Records and Healthcare Processes

Integration of Genetic and Familial Data into. Electronic Medical Records and Healthcare Processes Integration of Genetic and Familial Data into Electronic Medical Records and Healthcare Processes By Thomas Kmiecik and Dale Sanders February 2, 2009 Introduction Although our health is certainly impacted

More information

How Can Institutions Foster OMICS Research While Protecting Patients?

How Can Institutions Foster OMICS Research While Protecting Patients? IOM Workshop on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials How Can Institutions Foster OMICS Research While Protecting Patients? E. Albert Reece, MD, PhD, MBA Vice

More information

Certificate of Analysis

Certificate of Analysis Certificate of Analysis SMART-Seq v4 3 DE Kit Components Catalog No(s). Amount Lot Number 635042 (Not sold separately; Sold as a part of 635040) 96 rxns Specified on product label. 635043 (Not sold separately;

More information

Skin Science: The Use of

Skin Science: The Use of Skin Science: The Use of Genomics Tools in Skin Care Genemarkers LLC Anna Langerveld, PhD anna@genemarkersllc.com www.genemarkersllc.com Cosmeceuticals Summit March 9-11, 2009 Orlando, FL What is Skin

More information

CAP BIOINFORMATICS Su-Shing Chen CISE. 10/5/2005 Su-Shing Chen, CISE 1

CAP BIOINFORMATICS Su-Shing Chen CISE. 10/5/2005 Su-Shing Chen, CISE 1 CAP 5510-8 BIOINFORMATICS Su-Shing Chen CISE 10/5/2005 Su-Shing Chen, CISE 1 Genomic Mapping & Mapping Databases High resolution, genome-wide maps of DNA markers. Integrated maps, genome catalogs and comprehensive

More information

Services. Updated 05/31/2016

Services. Updated 05/31/2016 Updated 05/31/2016 Services 1. Whole exome sequencing... 2 2. Whole Genome Sequencing (WGS)... 3 3. 16S rrna sequencing... 4 4. Customized gene panels... 5 5. RNA-Seq... 6 6. qpcr... 7 7. HLA typing...

More information

Department of Biology Sample

Department of Biology Sample Syllabus BIOTECHNOLOGY Spring 2013 Instructor: Atanu Duttaroy, Professor Tel: 202-806-5362 Email: aduttaroy@howard.edu Office: Room 336, Just Hall Teaching Assistant: Mr. Subhas Mukherjee Lecture: Room

More information

About Time To Start a Biotech Business in Singapore? Money No Enough? (I Not Stupid?) (PIMPS; GIRLS) (PAP)

About Time To Start a Biotech Business in Singapore? Money No Enough? (I Not Stupid?) (PIMPS; GIRLS) (PAP) About Time To Start a Biotech Business in Singapore? Money No Enough? (I Not Stupid?) (PIMPS; GIRLS) (PAP) Biotech Stock out perform market 2x Record No of Biotech IPOs globally Major Biotech Companies

More information

MystiCq microrna cdna Synthesis Mix Catalog Number MIRRT Storage Temperature 20 C

MystiCq microrna cdna Synthesis Mix Catalog Number MIRRT Storage Temperature 20 C microrna cdna Synthesis Mix Catalog Number MIRRT Storage Temperature 20 C Product Description The microrna cdna Synthesis Mix has been designed to easily convert micrornas into cdna templates for qpcr

More information

Article 53(c) EPC - therapy

Article 53(c) EPC - therapy Article 53(c) EPC - therapy Compound X is not new, but no medical use (a) (b) (c) (d) (e) (f) (g) (h) (i) (j) (k) compound X for use as a medicament compound X for use in treating disease Y composition

More information

Appendix 2 Molecular Biology Core Curriculum. Websites and Other Resources

Appendix 2 Molecular Biology Core Curriculum. Websites and Other Resources Appendix 2 Molecular Biology Core Curriculum Websites and Other Resources Chapter 1 - The Molecular Basis of Cancer 1. Inside Cancer http://www.insidecancer.org/ From the Dolan DNA Learning Center Cold

More information

Reliable PCR Components for Molecular Diagnostic Assays

Reliable PCR Components for Molecular Diagnostic Assays Reliable PCR Components for Molecular Diagnostic Assays Terri McDonnell, MBA, PMP Senior Program Manager, Molecular Diagnostics March 2014 In this webinar we will: Discuss requirements for amplification

More information

Table 40: Product Profile - MS9 Table 41: MS9 SWOT Analysis, 2013 Table 42: Septin-9 CRC Screening Marketed Laboratory-Developed Tests Table 43:

Table 40: Product Profile - MS9 Table 41: MS9 SWOT Analysis, 2013 Table 42: Septin-9 CRC Screening Marketed Laboratory-Developed Tests Table 43: LIST OF TABLES 1.1 List of Tables Table 1: Initial Presenting Symptoms of Colorectal Cancer Table 2: Guideline Organization Recommendations for Non-Invasive Tests Table 3: TNM Classification System to

More information

Overview of Enabling Technologies in the Life Sciences. Professor Andrew Pitt, Aston University, Birmingham, UK

Overview of Enabling Technologies in the Life Sciences. Professor Andrew Pitt, Aston University, Birmingham, UK Overview of Enabling Technologies in the Life Sciences Professor Andrew Pitt, Aston University, Birmingham, UK Overview of Enabling Technologies in the Life Sciences Convergence Professor Andrew Pitt,

More information

Control of Gene Expression

Control of Gene Expression Control of Gene Expression What is Gene Expression? Gene expression is the process by which informa9on from a gene is used in the synthesis of a func9onal gene product. What is Gene Expression? Figure

More information

Using MATLAB: Bioinformatics Toolbox for Life Sciences

Using MATLAB: Bioinformatics Toolbox for Life Sciences Using MATLAB: Bioinformatics Toolbox for Life Sciences MR. SARAWUT WONGPHAYAK BIOINFORMATICS PROGRAM, SCHOOL OF BIORESOURCES AND TECHNOLOGY, AND SCHOOL OF INFORMATION TECHNOLOGY, KING MONGKUT S UNIVERSITY

More information

Mir-X mirna First-Strand Synthesis Kit User Manual

Mir-X mirna First-Strand Synthesis Kit User Manual User Manual Mir-X mirna First-Strand Synthesis Kit User Manual United States/Canada 800.662.2566 Asia Pacific +1.650.919.7300 Europe +33.(0)1.3904.6880 Japan +81.(0)77.543.6116 Clontech Laboratories, Inc.

More information

Vad är bioinformatik och varför behöver vi det i vården? a bioinformatician's perspectives

Vad är bioinformatik och varför behöver vi det i vården? a bioinformatician's perspectives Vad är bioinformatik och varför behöver vi det i vården? a bioinformatician's perspectives Dirk.Repsilber@oru.se 2015-05-21 Functional Bioinformatics, Örebro University Vad är bioinformatik och varför

More information

Just the Facts: A Basic Introduction to the Science Underlying NCBI Resources

Just the Facts: A Basic Introduction to the Science Underlying NCBI Resources 1 of 8 11/7/2004 11:00 AM National Center for Biotechnology Information About NCBI NCBI at a Glance A Science Primer Human Genome Resources Model Organisms Guide Outreach and Education Databases and Tools

More information

2016 Molecular Pathology Series (ASCPi)

2016 Molecular Pathology Series (ASCPi) Lecture Hall, Federation of Medical Societies of, 4th Floor, Duke of Windsor Social Service Building, 15 Hennessy Road, Wanchai, 12 Apr (TUE) Molecular Science I 1. Nucleic Acid Chemistry 2. Structure

More information

Overview of Next Generation Sequencing platform technologies

Overview of Next Generation Sequencing platform technologies Overview of Next Generation Sequencing platform technologies Dr. Bernd Timmermann Next Generation Sequencing Core Facility Max Planck Institute for Molecular Genetics Berlin, Germany Outline 1. Technologies

More information

ATIP Avenir Program 2014. Applicant s guide

ATIP Avenir Program 2014. Applicant s guide ATIP Avenir Program 2014 Applicant s guide Important dates: - November 29 th 2013: deadline for the online submission, the mailing of the hard copy of the scientific project, and the letters of recommendation

More information

Microarray Data Analysis Using Partek Genomic Suite. Xiaowen Wang Field Application Specialist Partek Inc.

Microarray Data Analysis Using Partek Genomic Suite. Xiaowen Wang Field Application Specialist Partek Inc. Microarray Data Analysis Using Partek Genomic Suite Xiaowen Wang Field Application Specialist Partek Inc. Who is Partek? Founded in 1993 Building tools for statistics & visualization Focused on genomics

More information

Joseph Wagner, Ph.D. Chief Executive Officer OncoCyte Corporation

Joseph Wagner, Ph.D. Chief Executive Officer OncoCyte Corporation Joseph Wagner, Ph.D. Chief Executive Officer OncoCyte Corporation Forward Looking Statements The matters discussed in this presentation include forward looking statements which are subject to various risks,

More information

REGULATIONS FOR THE POSTGRADUATE DIPLOMA IN MOLECULAR AND DIAGNOSTIC PATHOLOGY (PDipMDPath)

REGULATIONS FOR THE POSTGRADUATE DIPLOMA IN MOLECULAR AND DIAGNOSTIC PATHOLOGY (PDipMDPath) REGULATIONS FOR THE POSTGRADUATE DIPLOMA IN MOLECULAR AND DIAGNOSTIC PATHOLOGY (PDipMDPath) (See also General Regulations) M129 Admission requirements To be eligible for admission to the courses leading

More information

AP Biology Review Packet 4: Viruses, Bacteria and Expression & DNA Technology

AP Biology Review Packet 4: Viruses, Bacteria and Expression & DNA Technology AP Biology Review Packet 4: Viruses, Bacteria and Expression & DNA Technology 3A1- DNA, and in some cases RNA, is the primary source of heritable information. 3B1- Gene Regulation results in differential

More information

Complex Systems BioMedicine: Molecules, Signals, Networks, Diseases

Complex Systems BioMedicine: Molecules, Signals, Networks, Diseases The International School of Advanced Molecular BioMedicine Complex Systems BioMedicine: Molecules, Signals, Networks, Diseases AciTrezza (Catania), Italy, October 2nd-6th, 2009 Hieronymus Bosch: Garden

More information

Genomic Analysis Solutions from SAS

Genomic Analysis Solutions from SAS Genomic Analysis Solutions from SAS Russell Wolfinger Gerhard Held Development Director Solutions Manager Genomics Analytical Applications SAS Institute Inc. SAS International Pictures: Human Genome Program

More information