Epimed Would Like To Congratulate The 20th Annual Budapest Conference The New Shape of Pain Relief SmalleST. ThiNNeST. CoNTouRed design. Precision Novi is the world s smallest, thinnest 16 contact primary cell SCS device with a unique contoured shape. We d like to congratulate the Budapest Conference along with the WIP for 20 years of service and contributions to pain management. Epimed is honored to continue it s support of the WIP and pain physicians around the world. CAUTION: The law restricts these devices to sale by or on the order of a physician. Indications, contraindications, warnings and instructions for use can be found in the product labeling supplied with each device. Information for the use only in countries with applicable health authority product registrations Boston Scientific Precision Novi : Indications, contraindications and Instructions for use are included in the Instructions for Use contained in the product package. Precision Novi is a registered trademark of Boston Scientific Corporation or its affiliates. Images courtesy of Boston Scientific Corporation. All cited trademarks are the property of their respective owners. All Statements have been validated as of February 2015. Reference: Precision Novi Directions for Use (2015). Medtronic Prime Advanced Implant Manual (2006) St. Jude Eon C Sell Sheet (2009) NM-300006-AA_FEB2015 2015 Boston Scientific Corporation or its affiliates. All rights reserved. LT-169 Rev. 0

PERSONALISE PAIN MANAGEMENT ALL THE TIME. ANYTIME. AdaptiveStim HD Responds automatically by adjusting stimulation to your patient s preferred setting at any density. Learn more at professional.medtronic.com Note: Medtronic does not have clinical data on the efficacy of its devices when set at High Density Programming. www.medtronic.eu NEUROSTIMULATION SYSTEMS FOR PAIN THERAPY Brief Summary: Product manuals must be reviewed prior to use for detailed disclosure. Indication Neurostimulation for Spinal Cord Stimulation (SCS) Medtronic SCS neurostimulation system is indicated for SCS as an aid in the management of chronic, intractable pain of the trunk and/or limbs, peripheral vascular disease, or intractable angina pectoris. Neurostimulation for Peripheral Nerve Stimulation (PNS) using percutaneous leads - A Medtronic PNS neurostimulation system is indicated for PNS as an aid in the management of chronic, intractable pain of the posterior trunk. Neurostimulation for Peripheral Nerve Stimulation (PNS) using surgical leads A Medtronic PNS neurostimulation system is indicated for PNS as an aid in the management of chronic, intractable pain of the trunk and/or limbs. Contraindications Diathermy Do not use shortwave diathermy, microwave or therapeutic ultrasound diathermy (all now referred to as diathermy) on patients implanted with a neurostimulation system. Energy from diathermy can be transferred through the implanted system and cause tissue damage at the locations of the implanted electrodes, resulting in severe injury or death. Warnings Sources of strong electromagnetic interference (eg, defibrillation, diathermy, electrocautery, MRI, RF ablation, and therapeutic ultrasound) can interact with the neurostimulation system, resulting in serious patient injury or death. These and other sources of EMI can also result in system damage, operational changes to the neurostimulator or unexpected changes in stimulation. Rupture or piercing of the neurostimulator can result in severe burns. An implanted cardiac device (eg, pacemaker, defibrillator) may damage a neurostimulator, and the electrical pulses from the neurostimulator may result in an inappropriate response of the cardiac device. Patients treated for intractable angina pectoris should be educated on the signs and symptoms of myocardial infarction and should seek medical attention immediately if signs and symptoms develop. Precautions The safety and effectiveness of this therapy has not been established for pediatric use (patients under the age of 18), pregnancy, unborn fetus, or delivery. Patients should be detoxified from narcotics prior to lead placement. Clinicians and patients should follow programming guidelines and precautions provided in product manuals. Patients should avoid activities that may put undue stress on the implanted neurostimulation system components. Patients should not scuba dive below 10 meters of water or enter hyperbaric chambers above 2.0 atmosphere absolute (ATA). Electromagnetic interference, postural changes, and other activities may cause shocking or jolting. Patients using a rechargeable neurostimulator should check for skin irritation or redness near the neurostimulator during or after recharging. Adverse Events Adverse events may include: undesirable change in stimulation described by some patients as uncomfortable, jolting or shocking; hematoma, epidural hemorrhage, paralysis, seroma, CSF leakage, infection, erosion, allergic response, hardware malfunction or migration, pain at implant site, loss of pain relief, chest wall stimulation, and surgical risks. UC201503922EE 2015 Medtronic, Inc. All rights reserved. Printed in Europe. Not for distribution in France. When HAPPINESS leaves her speechless, the results say it all. 94% more patients achieved a back pain score of 2.5 with HF10 therapy vs. traditional SCS at 12 months. Source: Kapural, Leonardo et al. Novel 10-kHz High-frequency Therapy (HF10 Therapy) Is Superior to Traditional Low-frequency Spinal Cord Stimulation for the Treatment of Chronic Back and Leg Pain. Anesthesiology 123, no. 4 (2015). 2015106 Rev. A

wireless pain relief freedom Spinal Cord Stimulators INNOVATION. NOT IMITATION. Innovation means nothing without results. So while others may try to replicate the St. Jude Medical Burst waveform, ours is being supported by a growing body of evidence* and rigorous product development. At St. Jude Medical, we don t just advertise our innovation we prove it. The Most Versatile System: + + + MR 4 or 8 Electrodes, Polarity Select Low-Frequency, Adaptive Power High-Frequency, to 10 khz Spike Waveform Programming DRG Placements IPG-Free Percutaneous Procedure 1.5T & 3T MRI Full Body Conditional BURST STIMULATION ACCEPT. NO SUBSTITUTES. *Learn more at SJM.com/Burst Full Body MRI-Use under specific conditions for both 1.5T & 3T MRI scans. Refer to approved labeling for conditions. Indications for Use. The Freedom Spinal Cord Stimulator (SCS) System is intended as the sole mitigating agent, or as an adjunct to other modes of therapy used in a multidisciplinary approach for chronic, intractable pain of the trunk and/or lower limbs, including unilateral or bilateral pain. The Freedom System is contraindicated for patients who: are unable to operate the Freedom System, are poor surgical risks, are pregnant, have an occupational exposure to high non-ionizaing radiation, are implanted with cardiac system, or diathermy. Refer to the Instructions for Use provided with the Freedom SCS System or Stimwave.com for potential adverse effects, warnings, and precautions prior to using this product. Rx Only. Wireless Pain Relief is a registered trademark of Stimwave. 2015 Stimwave Technologies Incorporated. Unless otherwise noted, indicates that the name is a trademark of, or licensed to, St. Jude Medical or one of its subsidiaries. ST. JUDE MEDICAL and the nine-squares symbol are trademarks and service marks of St. Jude Medical, Inc. and its related companies. 2015 St. Jude Medical, Inc. All Rights Reserved. SJM-CPG-0515-0012(1) Item approved for global use.

Big things come in small packages. With its all-in-one design, Ziehm Solo is one of the most compact and versatile C-arms for crowded treatment scenarios. Equipped with state-of-the-art imaging technology, this C-arm delivers great performance for orthopedics, traumatology, pain management and other applications. Made in Germany. www.ziehm.com