Multiple Choice Write the letter that best answers the question or completes the statement on the line provided.

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Name lass Date hapter 12 DN and RN hapter Test Multiple hoice Write the letter that best answers the question or completes the statement on the line provided. Pearson Education, Inc. ll rights reserved. 1. What did riffith observe when he injected into mice a mixture of heat-killed disease-causing bacteria and live harmless bacteria? a. The disease-causing bacteria changed into harmless bacteria. b. The mice developed pneumonia. c. The harmless bacteria died. d. The mice were unaffected. 2. Which of the following is a nucleotide found in DN? a. ribose + phosphate group + thymine b. ribose + phosphate group + uracil c. deoxyribose + phosphate group + uracil d. deoxyribose + phosphate group + cytosine 3. DN replication results in two DN molecules, a. each with two new strands. b. one with two new strands and the other with two original strands. c. each with one new strand and one original strand. d. each with two original strands. 4. During mitosis, the a. DN molecules unwind. b. histones and DN molecules separate. c. DN molecules become more tightly coiled. d. nucleosomes become less tightly packed. 5. nlike DN, RN contains a. adenine. c. phosphate groups. b. uracil. d. thymine. 6. Which type(s) of RN is(are) involved in protein synthesis? a. transfer RN only b. messenger RN only c. ribosomal RN and transfer RN only d. messenger RN, ribosomal RN, and transfer RN 7. During transcription, an RN molecule is formed a. that is complementary to both strands of DN. b. that is complementary to neither strand of DN. c. that is double-stranded. d. inside the nucleus. hapter 12 Test 147

Name lass Date 8. How many codons are needed to specify three amino acids? a. 3 c. 9 b. 6 d. 12 9. Which of the following terms is LEST closely related to the others? a. intron c. polypeptide b. trn d. anticodon 10. Which type of RN functions as a blueprint of the genetic code? a. rrn c. mrn b. trn d. RN polymerase 11. Which of the following is NOT a gene mutation? a. inversion c. deletion b. insertion d. substitution 12. Which of the following statements is true? a. promoter determines whether a gene is expressed. b. n expressed gene is turned off. c. Proteins that bind to regulatory sites on DN determine whether a gene is expressed. d. RN polymerase regulates gene expression. 13. lac repressor turns off the lac genes by binding to a. the promoter. b. trn. c. the operator. d. the lac genes. 14. ene regulation in eukaryotes a. usually involves operons. b. is simpler than in prokaryotes. c. allows for cell specialization. d. includes the action of DN polymerase. 15. Which of the following statements is NOT true? a. Mutations do not occur in hox genes. b. Hox genes that are found in different animals X are very different from each other. c. Hox genes control the normal development of an animal. d. Hox genes occur in clusters. ompletion omplete each statement on the line provided. T Pearson Education, Inc. ll rights reserved. 16. The structure labeled X in Figure 12-1 is a(an). T Figure 12-1 148 hapter 12 Test

Name lass Date 17. The order of nitrogenous bases in DN determines the order of in proteins. 18. There is no that is specified by a stop codon on an mrn molecule. 19. The lac repressor releases the operator in the presence of. 20. In eukaryotes, proteins that attract RN polymerase bind to sequences in DN. Short nswer In complete sentences, write the answers to the questions on the lines provided. 21. t the beginning of DN replication, what two processes unzip the two strands of a DN molecule? B Figure 12-2 Pearson Education, Inc. ll rights reserved. 22. In Figure 12-2, which molecule is trn, and what is its function? 23. ccording to Figure 12-3, what codons specify the amino acid arginine? Valine rginine lanine Serine spartic acid Lysine sparagine lutamic acid Threonine lycine Methionine Isoleucine Phenylalanine rginine Leucine lutamine Serine Histidine Tyrosine Stop Proline ysteine Stop Tryptophan Leucine Figure 12-3 hapter 12 Test 149

Name lass Date 24. What happens to lac repressors in E. coli when lactose is present? 25. Why are hox genes that are found in different animals very similar to one another? sing Science Skills se the diagram below to answer the following questions on the lines provided. Methionine Phenylalanine D B E F Figure 12-4 26. Interpreting raphics What process is illustrated in Figure 12-4? 27. Interpreting raphics Identify structure in Figure 12-4. 28. Interpreting raphics Which labeled structure in Figure 12-4 is a codon? 29. Inferring What is the relationship between the codons and anticodons in Figure 12-4? How is this relationship important? 150 hapter 12 Test Pearson Education, Inc. ll rights reserved.

Name lass Date 30. Predicting In Figure 12-4, what will happen after the ribosome joins the methionine and phenylalanine? Essay Write the answer to each question in the space provided. 31. Describe the Hershey-hase experiment. Why were the results important? 32. Describe the structure of a DN molecule. Pearson Education, Inc. ll rights reserved. hapter 12 Test 151

Name lass Date 33. ontrast the functions of the three main types of RN. 34. Mendel might have been surprised to learn that genes simply contain the instructions for assembling proteins. What do proteins have to do with the phenotype of an organism? 35. Why do some kinds of point mutations cause greater changes in proteins than others? Pearson Education, Inc. ll rights reserved. 152 hapter 12 Test