Lugano Stem Cell Meeting Cardiocentro Ticino Lugano Switzerland 1 st -2 nd July 2008 PRELIMINARY PROGRAM UNDER THE PATRONAGE OF
Lugano Stem Cell Meeting In this first edition of the Lugano Stem Cell Meeting we would like to offer the opportunity to interact with the most important key opinion-leaders on stem cells. The first day focuses on GMP regulation of stem cell therapies and process manufacturing by listening to people directly involved in this field. Stem cell biology and regenerative medicine will also be widely discussed during the meeting. The second day is dedicated to the latest benchmarking and some ongoing clinical trials focusing on cellular therapy after acute STEMI and in chronic ischemic diseases. The meeting concludes with a discussion regarding present controversies and future challenges. Excellent talks and live cases from our cath-lab will improve the knowledge of these exciting topics. SCM can be followed entirely (from Tuesday 1 st July 9:50 a.m. to Wednesday 2 nd July 3:15 p.m.) or one day only. Learning objectives Update on current EU regulation on human cell-based medicinal products GMP translation of cell processing Critical discussions over the most debated topics of regenerative medicine Knowledge on ongoing clinical trials in patients after STEMI and with chronic ischemic diseases Understand and face current controversies and learn more about defining the optimal patient that could profit from cellular therapy Targeted audience Biologists Biotechnologists People involved in GMP processing (QA, QC, RA) Cardiologists Internists General practitioners On 2 nd July at 2:00 p.m. will start MTE 2008, 5 th Interventional Symposium on High Risk Coronary Intervention (common part until 3:15 p.m.). Please clearly tick in the registration form the sessions you will attend. We look forward to welcoming you in Lugano. With best regards Giuseppe Astori, Tiziano Moccetti, Gianni Soldati, Daniel Sürder
PRELIMINARY PROGRAM TUESDAY 1 S T JULY 2008 STEM CELLS FROM THE BENCHTOP TO THE CLINIC 09:20 09:50 Registration 09:50 10:00 Welcome address - T. Moccetti 10:00 10:10 Introduction - G. Soldati SESSION 1 Process Manufacturing and Regulation of Cell-Based Medical Products Chairmen: G. Astori, R. Giordano 10:10 10:35 The new Swiss regulation - C. Schärer 10:35 10:55 GMP regulation - P. Sanesi 10:55 11:15 The EU regulation on cell-based medicinal products(cbmp) - F. Bambi 11:15 11:25 Discussion 11:25 11:45 Coffee break SESSION 2 GMP Transfer of Clinical Protocols Chairmen: G. Soldati, K.C. Wollert 11:45 12:05 GMP cell processing of bone-marrow derived stem cells - G. Astori 12.05 12:25 Stem cell- based treatment for acute myocardial infarction: first experience from a controlled pilot phase I/II clinical trial - R. Giordano 12:25 12:45 Cardiac progenitor cells therapy of cardiovascular diseases - S. Bardelli 12:45 12:55 Discussion 13:20 14:00 Lunch - Satellite Symposium SESSION 3 Stem Cells Differentiation Potential Chairmen: M. Dominici, J. Hill 14:00 14:10 Introduction - M. Dominici 14:10 14:30 Molecular regulation of cardiac stem cell commitment - A. Leri 14:30 14:50 Cardiac stem cells and diabetic cardiomyopathy - J. Kajstura 14:50 15:10 Pim-1 kinase modulates cardiac stem cell growth and survival - M. Sussman 15:10 15:30 Discussion 15:30 15:45 Coffee break 15:45 16:05 Microenvironment changes and differentiation potential of bone marrow derived cells: the bone paradigm - M. Dominici 16:05 16:25 Epicardial Stem cells and cardiac regeneration - M. Capogrossi 16:25 16:45 Trafficking and homing of stem cells to repair the cardiovascular system. How to track the destiny of cells after therapeutic intravascular or intramyocardial delivery - J. Hill 16:45 16:55 Discussion 16:55 17.40 Closing Lecture: Human Cardiac Stem Cells - P. Anversa
PRELIMINARY PROGRAM WEDNESDAY 2 ND JULY 2008 STEM CELL THERAPY FOR CARDIOVASCULAR DISEASES 8:00 8:20 Registration 8:20 8:30 Introduction - T. Moccetti / P. Anversa SESSION 4 Chronic Ischemic Diseases Chairmen: G. Vassalli, J. Bartunek, F. Siclari 08:30 08:45 Surgical treatment of LV-dysfunction with CD133+ cells - G. Steinhoff 08:45 09:00 Adipose-Derived Cells for Chronic Myocardial Ischemia - F. Fernandez-Aviles 09:00 09:15 Ongoing Studies -Bone Marrow MSC for Repair of Chronically Infarcted Myocardium, FIH - J. Bartunek - Bone Marrow derived Cell Therapy in the Stable Phase of Chronic Ischemic Heart Disease - T. Moccetti / D. Sürder -YNSTEM trial - T. Torre 09:15 09:35 Second generation guided mesenchymal stem cells and heart repair - A. Terzic 09:35 09:55 Discussion 09:55 10:25 Coffee break SESSION 5 STEMI Chairmen: R. Corti, J. Hill, R. Giordano 10:25 10:40 Intracoronary infusion of bone marrow cells in patients after acute myocardial infarction from BOOST to BOOST 2; what have we learned? What can we expect? - K. Wollert 10:40 10:55 Selected, Enriched Hematopoitic Cells in STEMI - J. Bartunek 10:55 11:10 Apollo Trial - E.H.J. Duckers 11:10 11:20 SWISS-AMI - D. Sürder 11:20 11:35 Demonstration of cell processing in the cell laboratory 11:35 11.50 Discussion 11:50 12:15 Live case from the cath lab / operating room SESSION 6 Present Controversies and Future Challenges Chairman: Th. Lüscher - Panel: Whole Faculty 12:15 12:45 Main Lecture: From the Cell to the Muscle - Th. Lüscher 12:45 13:15 Round Table 13:15 14:00 Lunch Common part with 5 th INTERVENTIONAL SYMPOSIUM ON HIGH RISK CORONARY INTERVENTIONS MEET THE EXPERTS MTE2008 14:00 14:30 Welcome address - T. Moccetti / G. Pedrazzini 14:30 15:15 Special Guest Lecture 15:15 15:45 Coffee-breack - END OF THE LUGANO STEM CELL MEETING
FINAL PROGRAMME GENERAL INFORMATION Location The Lugano Stem Cell Meeting (SCM 2008) will take place in Lugano, the most important city in the Italianspeaking part of Switzerland. This region is considered to be one of the most beautiful spots in Europe. Venue The Meeting will take place at the Cardiocentro Ticino, which is located on the hill dominating the west of the city, less than 10 minutes walking distance from the central railway station and 10 minutes by taxi from the local airport (Lugano- Agno). The Milan Malpensa Airport is 1 hour by shuttle-bus from Lugano. By car: motorway exit Lugano Nord. Climate July often presents a warm temperature (23-27 C), with possible rain-showers. Certificate of Attendance A Certificate of Attendance will be given to the participants attending all sessions of the Meeting. Accreditation, CME Credits This Meeting is recognised by the following medical societies as accredited continuous education: EBAC, European Board for Accreditation in Cardiology: 11 CME credits. Swiss Society of Cardiology: 5 credits, category 1A. Under the patronage of the Working Community Regio Insubrica. Under the patronage of the Swiss Federal Office of Public Health. will only be granted if notification of cancellation has reached the conference secretariat before 9 th June 2008. Hotel Accommodation Participants are responsible for their own hotel booking. For assistance please contact: Letizia Bettoli Cardiocentro Ticino Via Tesserete 48-6900 Lugano, Switzerland Phone: +41 91 805 38 82 - Fax: +41 91 805 31 67 letizia.bettoli@cardiocentro.org Web Site On the web site of the Cardiocentro Ticino www.cardiocentro.org information is available about: Cardiocentro Ticino Venue Scientific program Conference secretariat contact details Conference Secretariat Please contact the secretariat in case of any query. Kindly send the registration forms to the secretariat at the following address: Ufficio Congressi Cardiocentro Ticino Via Tesserete 48-6900 Lugano Phone: +41 91 805 31 92 Fax: +41 91 805 31 67 congressi@cardiocentro.org LUGANO NORD motorway exit Conference Language The conference language is English for all sessions. No translation is provided. Vezia Crocifisso Savosa Pregassona Registration Fees 200 for the entire SCM, from Tuesday 1 st July 9:50 a.m. to Wednesday 2 nd July 3:45 p.m. 100 for single days. The deadline for registration is 9 th June 2008. The registration includes access to the scientific sessions and exhibition, all lunches and refreshment breaks of the sessions for which you are registered. Please see the enclosed registration form. Registration Cancellations Name changes or cancellations will only be accepted in writing. Refund of the registration fee (less 10%) AGNO airport Muzzano Noranco Breganzona Stazione FFS Sorengo Gentilino Paradiso LUGANO SUD motorway exit Ospedale Civico Via Tesserete Lugano
COURSE DIRECTORS - FACULTY COURSE DIRECTORS P. Anversa, Boston - USA G. Astori, Lugano - Switzerland T. Moccetti, Lugano - Switzerland G. Soldati, Lugano - Switzerland D. Sürder, Lugano - Switzerland FACULTY F. Bambi, Firenze - Italy S. Bardelli, Lugano - Switzlerland J. Bartunek, Aalst - Belgium M. Capogrossi, Milano - Italy R. Corti, Zürich - Switzerland M. Dominici, Modena - Italy E.H.J. Duckers, Rotterdam - The Netherlands F. Fernandez-Aviles, Madrid - Spain (contacted) R. Giordano, Milano - Italy J. Hill, London - UK J. Kajstura, Boston - USA A. Leri, Boston - USA Th. Lüscher, Zürich - Switzerland P. Pesenti, Bellinzona - Switzerland P. Sanesi, Poggibonsi - Italy C. Schärer, Bern - Switzerland F. Siclari, Lugano - Switzlerland G. Steinhoff, Rostock - Deutschland M. Sussman, San Diego - USA A. Terzic, Rochester - USA G. Vassalli, Lausanne - Switzerland K.C. Wollert, Hannover - Deutschland SPONSORS
Lugano Stem Cell Meeting 1 st -2 nd July 2008 Cardiocentro Ticino Lugano - Switzerland Family name First name Institute Department Institute Address Institute Postal code (int. Code: ++) e-mail Registration fees City Tel. Euro 200 for the entire SCM, from Tuesday 1 st July 9:50 a.m. to Wednesday 2 nd July 3:45 p.m. Country Fax Euro 100 for single days. Please tick as appropriate: Tuesday 1 st July 2008 Wednesday 2 nd July 2008 Payment I have instructed my bank to transfer the amount due with no costs to the beneficiary to Banca della Svizzera Italiana, account n. A339092F, Fondazione Cardiocentro, Congressi, 6900 Lugano Switzerland, with reference (participant s name) and enclosed is a copy of the transfer. SWIFT CODE: BSILCH22 - IBAN CODE: CH84084650000A339092F I would like assistance for hotel accomodation, please contact me: by phone: by fax: I would like to receive the brochure of the 5th Interventional Symposium on High Risk Coronary Intervention Meet the Experts 2008 REGISTRATION FORM For individual participant DEADLINE FOR REGISTRATION 9 TH JUNE 2008 TO BE RETURNED WITH ENCLOSURES TO Cardiocentro Ticino Congress Management Via Tesserete 48 - CH-6900 Lugano Phone +41 91 805 31 92 - Fax +41 91 805 31 67 congressi@cardiocentro.org