Stem cells: the diverging goals of regenerative medicine and oncology ROME JULY 1-2, 2010 CALL FOR ABSTRACTS

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1 Preliminary Programme INTERNATIONAL CONFERENCE Promoted by: Consiglio Nazionale delle Ricerche In collaboration with Stem cells: the diverging goals of regenerative medicine and oncology CHAIRMEN: KENNETH R. CHIEN (Boston, USA) GIANLUIGI CONDORELLI (Rome, I) LUCA GIANNI (Milan, I) CALL FOR ABSTRACTS

2 Scientific Committee Kenneth R. Chien, Director, MGH Cardiovascular Research Center Charles Addison and Elizabeth Ann Sanders, Professor Department of Cell Biology, Harvard Medical School Harvard Stem Cell Institute, Boston USA Gianluigi Condorelli, Director of Department of Medicine, National Council of Research (CNR), Rome Piero D. Dalerba, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California USA Luca Gianni, Director of Medical Oncology, National Cancer Institute, Milan Preliminary Programme SCIENTIFIC SECRETARIAT Fondazione Michelangelo Via Venezian, Milan I Phone Fax fmichel@istitutotumori.mi.it INTERNATIONAL CONFERENCE

3 Faculty Antonio Baldini, Naples I Thomas Brabletz, Freiburg D Kenneth R. Chien, Boston USA Michael F. Clarke, Stanford USA Francesco Cognetti, Rome I Gianluigi Condorelli, Rome I Giulio Cossu, Milan I Maria Grazia Daidone, Milan I Michele De Luca, Modena I Ruggero De Maria, Rome I Frederic J. De Sauvage, San Francisco USA Kevin Eggan, Cambridge USA Luca Gianni, Milan I Gianni Gromo, Basel CH Keigo Machida, Los Angeles USA Ravindra Majeti, Stanford USA Gerry Melino, Rome I Christine Mummery, Leiden NL Paolo Paoletti, Philadelphia USA Pier Giuseppe Pelicci, Milan I Lee Rubin, Cambridge USA Michael M. Shen, New York USA Andreas Trumpp, Heidelberg D Stem cells: the diverging goals of regenerative medicine and oncology

4 July 1st, SESSION 1 Opening lectures Chairmen: K.R. Chien (Boston, USA), G. Condorelli (Rome, I), L. Gianni (Milan, I) Introductory remarks K.R. Chien, Boston USA ips models of human neurodegenerative diseases K. Eggan, Cambridge USA Stem cells and cancer M.F. Clarke, Stanford USA Preliminary Programme Discussion INTERNATIONAL CONFERENCE

5 SESSION 2 Fostering committed maturation of stem cells Chairmen: K. Eggan (Cambridge, USA), G. Melino (Rome, I) Heart progenitors in development and disease K.R. Chien, Boston USA July 2nd, 2010 Chemical screens to direct reprogramming and differentiation L. Rubin, Cambridge USA Stem cells: the diverging goals of regenerative medicine and oncology

6 SESSION 3 Therapeutic applications in regenerative medicine Chairmen: A. Baldini (Naples, I), M.F. Clarke (Stanford, USA) Coffee break Mesangioblast cell therapy for muscular dystrophy G. Cossu, Milan I Towards heart regenerative therapy: challenges and opportunities C. Mummery, Leiden NL SESSION 3 Therapeutic applications in regenerative medicine Chairmen: A. Baldini (Naples, I), M.F. Clarke (Stanford, USA) Preliminary Programme July 2nd, Lunch Stem cells for corneal tissue repair and genetic skin disorders: clinical challenges M. De Luca, Modena I Stem cells and drug discovery: the road ahead G. Gromo, Basel CH INTERNATIONAL CONFERENCE

7 SESSION 4 Modelling cancer as a stem cells disease Chairmen: F. Cognetti (Rome, I), R. De Maria (Rome, I) Breast cancer initiating cells as drivers of disease and markers of prognosis P.G. Pelicci, Milan I Luminal epithelial origin of prostate cancer stem cells M.M. Shen, NewYork USA Stem cells of hepatocarcinoma K. Machida, Los Angeles USA Coffee break micrornas, EMT and cancer stem cells T. Brabletz, Freiburg D Stem cells: the diverging goals of regenerative medicine and oncology July 2nd, 2010

8 SESSION 5 Therapeutic applications in oncology Chairmen: M.G. Daidone (Milan, I), P. Paoletti (Philadelphia, USA) Monoclonal antibody targeting of cancer stem cells R. Majeti, Stanford USA Shh pathway inhibitors for the treatment of basal cell carcinoma and medulloblastoma F.J. De Sauvage, San Francisco USA Therapeutic implications of awakening quiescent cancer stem cells A.Trumpp, Heidelberg D Preliminary Programme July 2nd, Closing remarks K.R. Chien (Boston, USA), G. Condorelli (Rome, I), L. Gianni (Milan, I) INTERNATIONAL CONFERENCE

9 Conference General Information Conference Venue CNR, Consiglio Nazionale delle Ricerche P.le Aldo Moro, Rome, I Dates of the Conference FromThursday July 1st to Friday July 2nd, 2010 CME accreditation Applications to the competent bodies will be made to obtain approval for CME: EACCME for European and American (AMA) CME accreditation Royal College of Physicians for British CME accreditation Italian CME accreditation for Physicians and non-physicians Visa application - Letter of invitation EU citizens require only passport or national identity card to stay in Italy. Participants from other countries are advised to contact their nearest Italian Embassy or Consulate regardingvisa rules and regulations. Upon request, the Chairmen of the Conference will be happy to send a personal letter of invitation to enable participants to obtain support for Visa to attend the Conference. This announcement cannot be considered as an offer of financial support. Call for abstracts Deadline for receipt: June 11, 2010 DEADLINE WILL NOT BE EXTENDED. Abstracts will only be submitted through the electronic abstract form on the web site at: Registration Fee (Registration fee arevat included) Physicians Up to 35 years old 360,00 euro 120,00 euro Registration fee includes: Participation to all scientific sessions, congress material, coffee breaks, snack lunch and CME credits Cancellation and refund Refund of fee (by written request) with 30% administrative charge deduction, can be applied for until June 15th, After June 16th, 2010 no refund. Organizing Secretariat Effetti srl Via Gallarate, Milan I Phone Fax michelangelo@effetti.it Stem cells: the diverging goals of regenerative medicine and oncology

10 Application form Stem cells: the diverging goals of regenerative medicine and oncology Title: Dr Prof. Mr Ms Family Name First Name Company/Institute Mailing address Postal Code City Country Phone Fax PHYSICIAN 360,00 UP TO 35 YEARS OLD 120,00 Payment details All payment should be in euro and made out to Effetti srl. Methods of payment BANK TRANSFER To Effetti srl - Intesa San Paolo, Ag Via Ripamonti, Milan IBAN: IT68 P Please send a copy of your transfer order with this application form to Effetti srl (Via Gallarate Milan, Italy). CREDIT CARD Visa Eurocard/Mastercard Credit card no Expiry date I already authorized Effetti to debit my credit card for the total registration fee due: Date Signature

11 PRIVACY LAW IN ACCORDANCE WITH ARTICLE 23, ITALIAN LAW 196/03 I give my consent to the treatment and communication of my personal data, and to related usage methods and destination, to subjects performing activities as indicated in said information. I am aware that, by failing to give my consent, registration cannot be completed. IN ACCORDANCE TO ARTICLES 42 AND 43, ITALIAN LAW 196/2003 Lastly, I give my consent for data provided by myself to be transferred to associate, controlled or other companies with commercial relations with Effetti S.r.l., also outside European Union territory. I am aware that, by failing to give my consent, registration cannot be completed. Signature Signature IN ACCORDANCE WITH ARTICLE 7, ITALIAN LAW 196/03 I also give my consent for the data provided by myself to be used for the issue of information and commercial offers, also by third parties, and of advertising and informational material, for the completion of market research studies and the processing of commercial statistics. I am aware that, by failing to give my consent, registration cannot be completed. Signature To be sent to: Effetti srl - Via Gallarate Milan, I fax: michelangelo@effetti.it

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