Universal Data Acquisition (UDA)

Transcription

1 Universal Data Acquisition (UDA) I C P - O P T I C A L E M I S S I O N P R O D U C T N O T E Introduction Historically, Inductively Coupled Plasma (ICP) spectroscopy has been used for multiple analyte analysis with excellent speed, sensitivity and large linear dynamic range. Early ICP instruments used photomultiplier tubes for single wavelength analysis. Introduction of solid state detectors allowed for the acquisition of all wavelengths and background information resulting in data rich analyses. However, even with these advances, most users still only use one wavelength per analyte. Also, the ICP analyst is left with several questions: Did I use the best wavelength? What if I need information for another analyte? How can I achieve the appropriate detection limits or reporting limits? How can I handle all of the interferences in emission spectroscopy and still obtain the correct result? Universal Data Acquisition (UDA) addresses all of these problems by allowing for the simultaneous acquisition of all available wavelengths all of the time with a click of the mouse. UDA does not require a separate mode of analysis and uses a small amount of storage space. The resulting advantages of UDA are: Easy data validation Access to all analytes all the time no reruns necessary Easy to establish reporting limits for any analyte Unmatched interference correction capabilities

2 CASE 1 Is Your Data Validation Time Consuming? One of the most important processes for an analyst is the validation of data. It is critical that the certainty of every reported result be known. With UDA, if any uncertainty in the analysis result exists, it can be verified without ever rerunning the sample. In fact, multiple wavelengths can be reprocessed for each element to determine or confirm the correct result. Let s say you ran a Performance Test (PT) sample and the expected chromium concentration was 20 ppb. You got 14 ppb. This is only 70% recovery and the test would fail. You would normally need to rerun the analysis and include other chromium lines. Mean Data: Nist1643e Analyte Mean Corrected Intensity Calib. Conc. Units Std. Dev. Sample Conc. Units Std. Dev. RSD Y % % Cr mg/l mg/l % With UDA, all you have to do is add the other chromium lines to the method and hit the reprocess button. No reruns are necessary because UDA has already collected all information. You can see below that the Cr line gives 100% recovery without any additional run time. UDA not only saves precious time, but can insure the most accurate results. Mean Data: Nist1643e Analyte Mean Corrected Intensity Calib. Conc. Units Std. Dev. Sample Conc. Units Std. Dev. RSD Y % % Cr mg/l mg/l % Cr mg/l mg/l % Cr mg/l mg/l % Cr mg/l mg/l % Cr mg/l mg/l % Cr mg/l mg/l % 2

3 CASE 2 Tired of rerunning an analysis for additional analytes? Whether a lab is analyzing internal samples or those for an outside client, the potential for additional analyte requests exists. In some cases, the results reported initially may indicate further analytical testing. At other times, changes to regulations may prompt a re-investigation of previous samples for new analytes. These requests may occur hours, days or even years later. UDA and the UDA standards kit provide the capability to reprocess that data to include these new analytes without the need to rerun. Have you ever run a sample for five analytes and been asked to reanalyze the sample for a sixth? There is no need to recalibrate and rerun the sample if you used UDA along with the UDA standards kit! Just add the additional analyte(s) you need to the method and reprocess. The UDA standards contain virtually the entire periodic table, so you have already calibrated for all analytes even if you did not run them initially. If you started with a simple method, just add the additional analytes you would like into the method......and Reprocess Echellogram feature allows you to look at all of the analytes present in a simple way UDA gives you access to over 13,000 different analytical lines UDA Standards Kit 3

4 CASE 3 Determine reporting limits for all wavelengths Another common issue is determining whether or not the wavelength being used has the appropriate reporting limit for the analysis. Once again, most users run one wavelength and establish a reporting limit for that wavelength only. With UDA, the user can determine thousands of reporting limits at once and can simply choose the best one for the analysis. Let s say that you included Mn at nm into your method and then ran your IDL s, MDL s, or reporting limits on three non-consecutive days. That is a lot of time lost if you need to rerun it. With UDA, you don t. Add the other manganese lines into your method, choose your t-factor, reprocess and now you have validated limits for: Mn , Mn , Mn , Mn , Mn , Mn and Mn If the UDA standards kit is used for the calibration, you can have reporting limits and MDLs for thousands of wavelengths. MDL1 MDL2 MDL3 MDL4 MDL5 MDL6 MDL7 STDEV MDL PPB Ba Ca Fe Mg Mn Sr Zn V Ti Cr Ni Cu Pb Mg Ba Fe Zn As Sb Be Ag Cd Co Se Sn Tl Mo

5 CASE 4 Interference correction by Inter-Element Correction (IEC) or Multi-Component Spectral Fitting (MSF) In a typical analysis, the user must contend with perhaps tens of thousands of emission lines that may interfere with the chosen analyte line. Many regulated analyses require interference correction. It is important to confirm that the correct line is being used for the matrix being run. How can the optimal correction model be created? And, if the model being used is not correct, must the entire method development process be repeated? UDA is an easy answer to these questions without requiring reanalysis or new method development. UDA saves an immense amount of set up time and will improve laboratory productivity. Add Lines and Reprocess Interference correction You have already run all of the interference solutions that you need for the calculations and with UDA, you have collected all of the information for all of the wavelengths. Simply use the IEC or MSF tool, choose your alternative correction wavelength or profile and reprocess with the new model. There is no need to start over with method development. 5

6 PerkinElmer, Inc. 940 Winter Street Waltham, MA USA Phone: (800) or (+1) For a complete listing of our global offices, visit /ContactUs 2009 PerkinElmer, Inc. All rights reserved. The PerkinElmer logo and design are registered trademarks of PerkinElmer, Inc. All other trademarks not owned by PerkinElmer, Inc. or its subsidiaries that are depicted herein are the property of their respective owners. PerkinElmer reserves the right to change this document at any time without notice and disclaims liability for editorial, pictorial or typographical errors _01