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1 Photo by Riccardo Pellegrini Program Stazione Leopolda Pisa, Italy January 27-28, 2011

2 PATRONAGES Con il Patrocino dell Associazione Nazionale Medici Cardiologi Ospedalieri (ANMCO) SUPREMÆ DIGNITATIS IN Università di Pisa CHAIR Prof. Anna Sonia Petronio MD, FESC Head of Cardiac Catheterization Laboratory Cardiothoracic and Vascular Department University of Pisa Pisa, Italy Phone Fax [email protected] SCIENTIFIC SECRETARIAT Dr. Piersilvio Chella [email protected] Dr. Marco De Carlo [email protected] Dr. Cristina Giannini [email protected] Dr. Andrea Pieroni [email protected] Cardiothoracic and Vascular Department University of Pisa, Italy

3 WELCOME MESSAGE The meeting is motivated by the increasing interest in the new techniques for the transcatheter treatment of degenerative aortic stenosis and of mitral insufficiency. The ageing of population in the developed countries leads to an increase in the prevalence of these valvular diseases. Elderly patients are at higher risk for cardiac surgery, and are often denied conventional surgical treatment. In order to put a transcatheter valve programs into effect, it is necessary that all the different specialists involved in the management of these patients collaborate with one another: clinical cardiologists, echocardiographers, interventional cardiologists, cardiac surgeons and cardio-anesthesiologists. Knowledge of the various cardiovascular imaging techniques is also of paramount importance. Furthermore, with the increasing number of percutaneous valve procedures, clinical cardiologists need to know how to screen and follow-up these patients. Primary aim To broaden knowledge on the new transcatheter treatments for valvular diseases, with particular attention to patient selection, imaging techniques, and short- and long term patient care. I am looking forward to meeting you in Pisa

4 Scientific Program JANUARY, Thursday 27 TH Registration Congress Presentation A. S. Petronio 14.00/ st symposium - TAVI: which patients? Chairmen: S. Klugmann; L. Martinelli Risk evaluation: old and new scores F. Ettori The concept of patient fragility J. Bosmans Bicuspid aorta, degenerated bioprostheses: what else? J.C. Laborde Discussion 15.00/ nd symposium - Percutaneous Mitral Valve Repair: which patients? Chairmen: M. Emdin; R. Mariotti Surgical risk evaluation M. Glauber Eligibility for percutaneous treatment W. Schillinger Current and future percutaneous solutions F. Maisano Discussion Coffee break - Meet the Experts Lecture - Introduction by A. S. Petronio Evidence Based Medicine about percutaneous mitral valve repair S. Kar

5 17.00/ rd symposium - TAVI: management of comorbidities Chairmen: A. Marzocchi; G. Santoro How to deal with severe LV dysfunction A. B. Ramondo Coronary artery disease: problems and solutions R. Violini PAD: when to face it and when to get around it M. De Carlo Discussion JANUARY, Friday 28 TH / th symposium - Imaging of the mitral valve Chairmen: A. Balbarini; V. Di Bello Pre-operative Echocardiography G. La Canna Pre-operative MRI G. D. Aquaro Intra-procedural TEE F. Guarracino Discussion 09.30/ th symposium - Controversies about Mitral Regurgitation Chairmen: G. Minzioni; M.G. Bongiorni Epidemiology and prognosis of functional mitral regurgitation in chronic heart failure M. Metra

6 09.45 Advanced chronic heart failure: is correction of mitral regurgitation a further option? M. Senni MitraClip for Degenerative or Functional MR? G. P. Ussia Discussion Coffee break - Meet the Experts Lecture - Introduction by A. S. Petronio Evidence Based Medicine about percutaneous aortic valves P. De Jaegere 11.30/ th symposium - Teamwork! Chairmen: M. Marzilli; P. Presbitero When I propose for TAVI: the point of view of the Cardiologist U. Gerckens When I choose TAVI: the point of view of the Cardiac Surgeon A. Jönsson The choice of sedation and anaesthesia B. Eberle Discussion 12.30/14.15 Lunch session - 30 minutes vis-à-vis session Abbott Vascular Edwards Medtronic For more details please see the Scientific Information.

7 14.15/15.00 ROUND TABLE - Managing Technological Innovation in healthcare: current state of the art and future challenges for the Italian NHS Speaker: R. Tarricone Discussants: L. Anselmi; L. Bolognese; F. M. Bovenzi; G. F. Gensini 15.00/ th symposium - Imaging of the aortic valve Chairmen: P. Marraccini; C. Pierli Echo is enough! E. Brochet CT is mandatory! G. Ballerini New angiographic tools S. Berti Discussion 16.00/ th symposium - Controversies about TAVI Chairmen: D. Antoniucci; U. Bortolotti Durability of percutaneous valves N. Piazza Post-TAVI conduction abnormalities F. Bedogni Paravalvular leak post TAVI- assessment and clinical implications G. Mikhail Discussion Take home message A.S. Petronio

8 FACULTY Aquaro Giovanni Donato PISA (ITALY) Anselmi Luca PISA (ITALY) Antoniucci David FIRENZE (ITALY) Balbarini Alberto PISA (ITALY) Ballerini Giovanni MILANO (ITALY) Bedogni Francesco MILANO (ITALY) Berti Sergio MASSA (ITALY) Bolognese Leonardo AREZZO (ITALY) Bongiorni Maria Grazia PISA (ITALY) Bortolotti Uberto PISA (ITALY) Bosmans Johan ANTWERPEN (BELGIUM) Bovenzi Francesco Maria LUCCA (ITALY) Brochet Eric PARIS (FRANCE) De Carlo Marco PISA (ITALY) De Jaegere Peter ROTTERDAM (THE NETHERLANDS) Di Bello Vitantonio PISA (ITALY) Eberle Balthasar BERN (SWITZERLAND) Emdin Michele PISA (ITALY) Ettori Federica BRESCIA (ITALY) Gensini Gian Franco FIRENZE (ITALY) Gerckens Ulrich SIEGBURG (GERMANY) Glauber Mattia MASSA (ITALY) Guarracino Fabio PISA (ITALY) Jönsson Anders STOCKHOLM (SWEDEN) Kar Saibal LOS ANGELES (USA) Klugmann Silvio MILANO (ITALY) La Canna Giovanni MILANO (ITALY) Laborde Jean-Claude LONDON (UK) Maisano Francesco MILANO (ITALY) Mariotti Rita PISA (ITALY) Marraccini Paolo PISA (ITALY) Martinelli Luigi MILANO (ITALY) Marzilli Mario PISA (ITALY) Marzocchi Antonio BOLOGNA (ITALY) Metra Marco BRESCIA (ITALY) Mikhail Ghada LONDON (UK) Minzioni Gaetano PISA (ITALY) Petronio Anna Sonia PISA (ITALY) Piazza Nicolò MUNICH (GERMANY) Pierli Carlo SIENA (ITALY) Presbitero Patrizia MILANO (ITALY) Ramondo Angelo Bruno VICENZA (ITALY) Santoro Gennaro FIRENZE (ITALY) Schillinger Wolfgang GOTTINGEN (GERMANY) Senni Michele BERGAMO (ITALY) Tarricone Rosanna MILANO (ITALY) Ussia Gian Paolo CATANIA (ITALY) Violini Roberto ROMA (ITALY)

9 SCIENTIFIC INFORMATION Presentations Presentations will be projected through a personal computer which will be provided by the Conference Secretariat. The use of personal laptop is not permitted. The presentation must be provided in PowerPoint and must be submitted at least 1 hour before the beginning of the session to the Slides Center on a CD-Rom or a Pen Drive. Please remember that WINDOWS will be the only accepted Operating System. Continuing Medical Education C.M.E. credits has been requested to the Italian Accreditation Council for Continuing Medical Education (E.C.M.) for the following medical specialities: cardiology, geriatrics, internal medicine, heart surgery, anaesthesia and resuscitation, radio-diagnostics. C.M.E. certificates will be sent out to all delegates (by ) who will attend the meeting and who will successful complete the C.M.E. questionnaire and evaluation form. Lunch Session - Face-to-Face Appointments During the lunch session (Jan. 28) participants may wish to attend the 3 face-to-face meetings scheduled every 30 minutes at the following meeting rooms: ABBOTT, EDWARDS and MEDTRONIC. Packet lunch will be delivered to attendants at the entrance of the meeting rooms. Cult 2011 Expo An Exhibition on Laboratory & Scientific Products will be open to attendants at the Exhibit Hall during the conference time. Participants will gain an understanding of the latest advances in pharmaceuticals, imaging, devices and the services that they might need to help them provide high quality patient care. The CULT 2011 Expo will feature innovative cardiovascular products and services being shown by outstanding exhibiting companies. Official Languages Italian and english will be spoken during the conference. Simultaneous translation will be provided.

10 GENERAL INFORMATION Congress Venue Stazione Leopolda Piazza Francesco Domenico Guerrazzi, Pisa, Italy Phone Fax Secretariat The Secretariat will be open at the Congress Venue starting from pm on January 27th, throughout the event. Certificate of Attendance Certificate of attendance will be provided to all registered delegates on-site at finishing time of the conference. Registrations REGISTRATION FEE (20% V.A.T included) 2 Days conference 1 Day conference After October 30, 2010 E 300,00 E 250,00 On site E 360,00 E 310,00 The fee includes: taxes, access to the conference, conference kit. Lunch and coffee breaks for the attendance on the 28th. Payment You may choose to pay through one of the following methods: PAYMENT BY CREDIT CARD (Visa, Mastercard) by filling the specific box in the registration form PAYMENT BY BANK TRANSFER with the following details: Bank Name: Monte dei Paschi di Siena Agenzia n. 3 Bank Address: Via Scornigiana Loc. Ospedaletto Pisa Italy Account Name: Meridiana Events & Education srl Bank Account number: ABI CODE: CAB CODE: IBAN CODE: IT 42 Z BIC SWIFT CODE: PASCITM1PI3. Bank transfer must detailed by REGISTRATION (in case of 1 day attendance please specify the date) + NAME OF PARTICIPANT + CULT2011 Sender must pay for bank fees. In case bank fees are charged to the conference account, Meridiana will invoice the sender with the bank fees plus 20% handling fee + taxes. Pre-registration will be accepted until January 20, After this date only on site registration will be accepted. REGISTRATION FEE INCLUDES: Access to the education sessions and conference kit. Lunch and coffee breaks are included only for the attendance on the 28th. CANCELLATION POLICY: any cancellation must be sent in writing by letter, fax or , not by phone. Cancellations received before November 15, 2010 are refundable less a cancellation fee of E 60,00 (including 20% vat) per person. No refunds can be made after November 15, 2010 at any circumstances. REFUNDS: all refunds will be issued by bank transfer within 60 days of the conference s conclusion. DISCLAIMER: Meridiana Events & Education will not accept liability for any losses and/or damages participants may suffer on account of alteration or cancellation for any reason including ill health. Participants are advised to arrange adequate travel and health insurance. NAME SUBSTITUTIONS: can be made at any time for an administration fee of Eur 50,00 (including 20%) per person. Hotel Reservation For hotel reservation please contact Meridiana Events & Education: [email protected] Phone:

11 The Organizing Committee wishes to thank: PLATINUM SPONSOR

12 ORGANIZING SECRETARIAT Meridiana Events & Education srl Paola Benedetti Via A. Cocchi trav A n Pisa Italy Phone Fax [email protected]

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