Corporate support will be acknowledged both verbally and in future printed materials. AACE will be the accredited provider for this CME program

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2 COURSE DESCRIPTION The Advances in Medical and Surgical Management of Thyroid Cancer course will provide an evidence-based update on the contemporary management of thyroid cancer from diagnosis to treatment. A diverse faculty of endocrinologists and surgeons will cover epidemiology, microcancer, nodule evaluation, selective I-131 use, risk stratification, initial and repeat surgical interventions as well as management of advanced disease and other timely topics. Individual cases will be presented in an interactive format with the panel experts. The utility of ultrasound will be highlighted in the lectures as well as in patient demonstrations. TARGET AUDIENCE The target audience for this activity is endocrine surgeons, ENT and head and neck surgeons, radiologists, thyroidologists and endocrinologists, nuclear medicine physicians, nurse practitioners, physician assistants, and sonographers. NEEDS ASSESSMENT Care of patients with thyroid nodules varies widely, and differentiating benign nodules from malignancy requiring management remains a clinical challenge. Patients with thyroid nodules may be over- or under-treated for their disease. Clinicians need education on the latest updates to clinical practice guidelines to understand treatment algorithms for patients with thyroid cancer. Clinicians need additional information about recently published clinical results, including advances in diagnosis, imaging, staging, and surveillance as well as surgical and systemic management of thyroid cancer. The application of the current clinical practice guidelines, including recent updates is necessary to improve overall patient care. OVERALL LEARNING OBJECTIVES Upon successful completion of the activity, participants should be better able to: Discuss evidence-based practices and current guidelines for the management of thyroid nodules and cancer Evaluate recent advances in imaging and surveillance in thyroid cancer Discuss clinical decision-making and the latest evidence for surgical and systemic management of thyroid cancer Corporate support will be acknowledged both verbally and in future printed materials. AACE will be the accredited provider for this CME program

3 PROGRAM AGENDA SATURDAY, JANUARY 14, :30 7:00 REGISTRATION / BREAKFAST 7:00 7:30 THYROID CANCER EPIDEMIOLOGY AND THE MICROCANCER CONUNDRUM Daniel Duick, MD, FACP, MACE, ECNU 7:30 8:00 THYROID NODULE RISK STRATIFICATION AND FNA GUIDELINES Mark A. Lupo, MD, FACE, ECNU 8:00 8:45 MOLECULAR GENETIC TESTING IN CLINICAL THYROIDOLOGY PRACTICE Steven P. Hodak, MD 8:45 9:15 COFFEE BREAK & EXHIBITS 9:15 10:00 THYROID FINE NEEDLE ASPIRATION: DIAGNOSIS, CHALLENGES AND SOLUTIONS Zubair W. Baloch, MD 10:00 10:45 PRE-OPERATIVE ULTRASOUND IN THYROID CANCER Robert A. Levine, MD, FACE, ECNU 10:45 11:30 INITIAL SURGERY FOR DIFFERENTIATED THYROID CANCER WHAT IS THE APPROPRIATE EXTENT AND ATTENDANT RISKS AND BENEFITS? Julie Ann Sosa, MD, MA, FACS 11:30 12:30 PANEL DISCUSSION Moderator: Mark A. Lupo, MD, FACE, ECNU 12:30 1:30 LUNCH 1:30 2:45 SCAN PATIENTS IN GENERAL SESSION AUDIENCE AND PANEL DISCUSSION Mark Lupo, MD, FACE, ECNU; Bob Levine, MD, FACE, ECNU; Dev Abraham, MD, MRCP, FACE, ECNU 2:45 3:15 COFFEE BREAK & EXHIBITS 3:15 4:00 DYNAMIC RISK STRATIFICATION: USING RISK ESTIMATES TO GUIDE INITIAL MANAGEMENT R. Michael Tuttle, MD

4 4:00 4:45 THYROID CANCER I 131 DOSING AND TREATMENT: AN UPDATE ON RISK STRATIFICATION, RAI THERAPY OPTIMIZATION AND RADIATION RISK REDUCTION Stephanie Lee, MD, PhD, FACE, ECNU 4:45 5:45 PANEL DISCUSSION Moderator: Robert A. Levine, MD, FACE, ECNU 5:45 ADJOURN 7:00 7:30 BREAKFAST SUNDAY, JANUARY 15, :30 8:15 MANAGEMENT OF LYMPH NODES IN THE SETTING OF A NEW DIAGNOSIS OF DIFFERENTIATED THYROID CANCER Julie Ann Sosa, MD, MA, FACS 8:15 9:00 PRACTICAL APPLICATION OF US AND TG FOR POST-OP SURVEILLANCE Dev Abraham, MD, MRCP(UK), FACE, ECNU 9:00 9:45 RISK ADAPTED FOLLOW UP: INDIVIDUALIZING FOLLOW UP STRATEGIES R. Michael Tuttle, MD 9:45 10:15 COFFEE BREAK & EXHIBITS 10:15 11:00 SURGERY FOR RECURRENCE AND LOCALLY ADVANCED DISEASE Gary Clayman, DMD, MD, FACS 11:00 11:45 SYSTEMIC TREATMENT FOR DIFFERENTIATED AND MEDULLARY THYROID CARCINOMA WHAT, WHY, WHEN AND HOW? Mimi Hu, MD 11:45 12:00 LUNCH BREAK (CHECK OUT OF ROOM PICK UP BOXED LUNCH, GS FOR CASE DISCUSSION) lunch, GS for case discussion) 12:00 1:30 ADVANCED CASE DISCUSSIONS Moderator: Dev Abraham, MD, MRCP(UK), FACE, ECNU 1:30pm ADJOURN

5 PROGRAM FACULTY *Devaprabu Abraham, MD, MRCP (UK), FACE, ECNU PROGRAM CO-CHAIR PROFESSOR OF CLINICAL MEDICINE, SURGERY AND PATHOLOGY DIRECTOR OF UTAH DIABETES AND ENDOCRINE CENTER UNIVERSITY OF UTAH SALT LAKE CITY, UT Zubair W. Blaloch, MD PHILADELPHIA, PA Gary L. Clayman, DMD, MD, FACS DIRECTOR, CLAYMAN THYROID CANCER CENTER TAMPA GENERAL HOSPITAL TAMPA, FL * Daniel S. Duick, MD, FACP, MACE, ECNU PROGRAM CO-CHAIR CLINICAL PROFESSOR OF MEDICINE UNIVERSITY OF ARIZONA HEALTH SCIENCES CENTER ENDOCRINOLOGY ASSOCIATES, PA PHOENIX, AZ Steven Hodak, MD PROFESSOR OF MEDICINE AND ENDOCRINOLOGY ASSOCIATE DIRECTOR: DIVISION OF DIABETES AND ENDOCRINOLOGY NYU SCHOOL OF MEDICINE NEW YORK, NY Mimi Hu, MD ASSOCIATE PROFESSOR DEPARTMENT OF ENDOCRINE NEOPLASIA AND HORMONAL DISORDERS UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER HOUSTON, TX Stephanie Lee, MD, PhD, FACE, ECNU ASSOCIATE PROFESSOR OF MEDICINE DIRECTOR OF THE THYROID HEALTH CENTER BOSTON UNIVERSITY SCHOOL OF MEDICINE BOSTON MEDICAL CENTER BOSTON, MA

6 Robert A. Levine, MD, FACE, ECNU ADJUNCT ASSISTANT PROFESSOR OF MEDICINE GEISEL SCHOOL OF MEDICINE DARTMOUTH MEDICAL SCHOOL THYROID CENTER OF NEW HAMPSHIRE ST. JOSEPH HOSPITAL ENDOCRINOLOGY NASHUA NH * Mark A. Lupo, MD, FACE, ECNU PROGRAM CO-CHAIR THYROID & ENDOCRINE CENTER OF FLORIDA ASSISTANT CLINICAL PROFESSOR OF MEDICINE FLORIDA STATE UNIVERSITY, COLLEGE OF MEDICINE SARASOTA, FLORIDA Julie Ann Sosa, MD, MA, FACS PROFESSOR OF SURGERY AND MEDICINE (ONCOLOGY) CHIEF, SECTION OF ENDOCRINE SURGERY DIRECTOR, SURGICAL CENTER FOR OUTCOMES RESEARCH LEADER, ENDOCRINE NEOPLASIA DISEASES GROUP, DUKE CANCER INSTITUTE AND DUKE CLINICAL RESEARCH INSTITUTE DUKE UNIVERSITY MEDICAL CENTER DURHAM, NC R. Michael Tuttle, MD PROFESSOR OF MEDICINE MEMORIAL SLOAN-KETTERING CANCER CENTER NEW YORK, NY * Indicates Program Committee REGISTRATION INFORMATION TO REGISTER ONLINE OR FOR MORE INFORMATION $795...(AACE Member MD or DO) $ (Nonmember MD, DO) $ (Non-Physicians or Fellow-in- Training) Cancellation Policy: All Course cancellations must be received in writing in the AACE office 30 days prior to the first day of the course to receive a full refund less a $50 processing fee. Cancellations or no shows received after that date will not be refunded, except in extenuating circumstances. In this case, a request must be made in writing, and such requests for refund will be at the discretion of the program chair(s).

7 AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS Advances in Medical and Surgical Management of Thyroid CancerTM Tampa, Florida COURSE LOCATION Renaissance Tampa International Plaza Hotel 4200 Jim Walter Blvd. Tampa, FL Hotel Reservations: or Refer to the AACE Thyroid Meeting on or before Tuesday, December 20, 2016 to receive the group rate of $ Book online at: Staying for a couple extra days? For tourist information on the Tampa Bay area: For tourist information on Florida:

8 AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS 245 Riverside Avenue, Suite 200 Jacksonville, FL PRESORT STANDARD US POSTAGE PAID JACKSONVILLE, FL PERMIT #4346

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