BIOCITY COMBINING BIOSCIENCES OF TWO UNIVERSITIES

Transcription

1 BIOCITY COMBINING BIOSCIENCES OF TWO UNIVERSITIES John E. Eriksson Turku Centre for Biotechnology University of Turku & Åbo Akademi University

2 THE CITY OF TURKU (ÅBO), FINLAND The oldest town in Finland (since 1229), the main city of the South-West part of the country, inhabitants The home of the first university in Finland, Åbo Akademi (est. 1640)

3 BioCity Turku is an umbrella organization supporting and coordinating life science and molecular medicine related research in the University of Turku and Åbo Akademi University University of Turku Åbo Akademi University Turku University Central Hospital

4 Provides state-of-the-art research facilities and develops technologies Turku Centre for Biotechnology DNA microarrays Proteomics Bioinformatics Turku BioImaging Turku Centre for Disease Modeling

5 TURKU SCIENCE PARK AREA AN INTEGRAL 5 KM² CAMPUS AREA WITH A WALKING DISTANCE FROM THE CITY CENTRE The existence of one compact, multidisciplinary campus area is the major strength of science in Turku. The geographical structure of the campus is unique in Finland and an optimal platform for interdisciplinary collaboration and the integration of science. BioCity Turku

6 Turku Bioimaging Turku Bioimaging From atoms to anatomy

7 Turku Bioimaging From atoms to anatomy NANOSCALE IMAGING Latest instruments and best expertise Latest probes and methods Latest image analysis tools in vivo IMAGING OF HUMANS AND ANIMALS CELL AND TISSUE IMAGING

8 8 Stefan W. Hell

9 Stefan Hell and STED microscopy Hell did his post-doctoral training in Turku and discovered several key principles: MP, 4Pi, STED STED microscopy the fundamental diffraction barrier of light can be broken Confocal STED

10 Biomedical in vivo Imaging infrastruture in the Turku PET Centre Imaging Platform Optical imaging system 3T MRI/PET Philips 1,5 T MRI GE VCT PET/CT 64-slice CT Micro-CT Animal US Animal/human PET HRRT GE D690 PET/CT Fuji FLA-7000 Phosphor imaging device Siemens Inveon multimodality Animal PET/CT Human Digital US SIEMENS PET HR+ Ex vivo In vivo non-clinical Clinical

11 Master s Degree Programme in Biomedical Imaging Jointly administered by University of Turku and Åbo Akademi University Open to students with BSc Degree in biomedical or medical sciences, physics, engineering, chemistry etc. Duration 2 years No tuition fees Language of instruction: English quota max. 25 students/year Åbo Akademi University Domkyrkotorget Åbo

12 TURKU BIOIMAGING Impacts, effects, and possibilities Prominent publications Recognition and visibility External funding Jobs, services, and industry

13 Euro-Bioimaging - The global gate to the forefront of European biological and medical maging A project on the ESFRI Roadmap for Research Infrastructures John E. Eriksson Turku Center for Biotechnology University of Turku and Åbo Akademi University

14 A Revolution in Bioimaging Technologies Transcripts Genomes Nucleotides Tissues and organs Biobanks Human populations Complexes Therapies Proteins Disease prevention Domains Pathways Structures Small molecules Cells Human individuals Early Diagnosis

15 Participate in the Revolution in Bioimaging Technologies Transcripts Genomes Nucleotides Tissues and organs Biobanks Human populations Complexes Therapies Proteins Disease prevention Domains Pathways Structures Small molecules Cells Human individuals Early Diagnosis

16 Introduction European Strategy Forum on Research Infrastructures (ESFRI) Optimize use & development of Research Infrastructures (RI) Support a coherent approach to policy-making on RI s Strengthen the European Research Area Facilitate multilateral initiatives Mobilize scientific communities in Europe Foster Europe s international outreach

17 Group of 13 ESFRI BMS RIs ANAEE ISBE MIRRI BMS RI Strategy Paper

18 Enabling Excellent Research Imaging Technologies Technology Development drives Excellent Research

19 Imaging is the most requested research infrastructure Source: Biocenter Finland Survey 2012 Source: Biocenter Finland Survey 2015

20 Mission & Scope

21 Europe s Research Infrastructure for Imaging Technologies Services to be provided Access to cutting-edge biological & medical imaging technologies with high-level user support by expert technical staff Image data repositories and analysis tools Advanced training for users and providers of imaging technologies by Hub and Nodes Euro-BioImaging HUB Coordination & support of access, data, training European infrastructure management Flagship Technology NODES Access to unique imaging technology in Europe Multimodal Technology NODES Integrated access to multiple imaging technologies

22 European nodes for open access imaging infrastructres Euro- BioImaging access Increased capacity for European access National imaging centers Established national excellence in open access imaging infrastructures

23 By modest additional funding for EuBI access, the future nodes will provide an amazing imaging platform for European researchers Platform of European imaging excellence open to all researchers Established national centers for open access imaging

24 FLAGSHIP NODE FLAGSHIP NODE FLAGSHIP NODE FLAGSHIP NODE Imaging Infrastructure with physical open user access HUB NODES Provides: - STAFF TRAINING - USER TRAINING Multimodal Technology NODE Multimodal Technology NODE Data storage and analysis infrastructure User goes home with results for publication

25 Identification of new technologies

26 Operation From Construction Phase to Operation Interim=>Construction phase Main tasks: Hub operation, preparation for node construction Upgrades of operational facilities to best meet the national and international needs for imaging services Node construction Setting up communication and quality control procedures between the hub and nodes Setting up training procedures and routines Evaluation structure of the users applying for access to different infrastructures Securing a funding structure

27 Approved Hub Proposal ERIC Statutory Seat Web access portal User Access Director General Director s office External relations Administration & Legal affairs Data services Quality control & Research infrastructure evaluation Identification of novel technologies EuBI Board & SAB Secretariat Finland User Access Training coordination Support of bio-eubi Nodes Support national bio imaging initiatives Bio- Hub Training coordination Support of med-eubi Nodes Support national med imaging initiatives Med-Hub Italy

28 EuBI Node Candidates Nominations for 1 st generation of Euro- BioImaging Nodes: Call for nominations was open until 1 July Nodes were nominated by 11 IB members 29 Nodes ratified 28 Node Candidates offering services during the Interim Operation

29 Web Access Portal

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31 User access: Web Access Portal Submission and review of access applications Objective and transparent 2- step review process Other features: Access portal to image data repository, processing tools and cloud services Management of training activities (information, application submission, evaluations) Management of quality control Multi-level online communication platform Tools for identifying and assessing new imaging technologies Tools for real-time data collection of all EuBI activities

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