INVITATION. Prof. Dr. Ayfer Haydaroğlu. Dear Colleagues,

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2 INVITATION Dear Colleagues, The International Symposium on Cancer Nanomedicine will be held in Ege University, School of Medicine, Izmir, Turkey between 7-9 November 2013, with the contributions of Ege University, Izmir Institute of Technology, Katip Celebi University, Dokuz Eylul University and Gediz University. During this event, contributions of nanotechnology in the field of oncology including the current status of nanomedicine in oncology and the importance of targeted imaging and therapy strategies will be discussed. Internationally renowned scientists will share their research and perspectives on nanomedicine. Multidisciplinary interactions and discussions will be further stimulated through oral and poster presentations of original research. Medical technologies today have been reduced to nanoscales, and nanotechnology has been applied in various fields of medicine. Reflections of this progress can be observed in the field of cancer diagnosis and treatment. Aforementioned Symposium aims to gather scientists and engineers, from the field of nanotechnology, with medical doctors and pharmaceutical scientists, working on diagnosis and treatment of cancer, and facilitate a mean for collaborations and novel project ideas. Within the events, "The Best Poster" and "The Best Hypothesis" competitions will be also held. "The Best Poster" will receive an award. "The Best Hypothesis" award will be limited to graduate and undergraduate students. The organization of the symposium has been led by Ege University Cancer Reseach and Practice Center and supported by Ege University School of Medicine, School of Pharmacy and Department of Bioengineering, Izmir Institute of Technology Faculty of Science and Faculty of Engineering, Dokuz Eylul University School of Medicine, Katip Celebi University School of Engineering and Gediz University School of Engineering. As the chair of The International Symposium on Cancer Nanomedicine, it is my belief that this event will serve to the prospects of researchers, both oncologists and scientists/engineers, interested in the field of nanomedicine, especially providing means for the conception of novel multidisciplinary studies. Prof. Dr. Ayfer Haydaroğlu

During this event, contributions of nanotechnology in the field of oncology including the current status of nanomedicine in oncology and the importance of targeted imaging and therapy strategies will

3 ORGANIZING COMMITTEE Honorary President Candeger Yilmaz President Ayfer Haydaroglu Scientific Secretariat Volga Bulmus Members Aylin Sendemir Bulent Karabulut Engin Özcivici Gül Kitapçıoğlu Hadi Zareie Kemal Baysal Mehmet Sengün Ozsoz Ozgur Omur Scientific Committee Senem Alanyali Yusuf Baran A. Filiz Oner Adil Denizli Ahmet Ozet Ali Ugur Ural Ali Tuncel Arlin Kiremitci Aysel Yurtsever Aysegül Akgun Berrin Erdag Beste Atasoy Bulent Karabulut Can Ozen Candan Tamerler Cumhur Gunduz Dicle Guc Emin Kansu Emir Baki Denkbas Engin Umut Akkaya Engin Ulukaya Ercument Karasulu Erdal Bedir Erdem Goker Erhan Biskin Erhan Gökmen Eylem Guven Faruk Zorlu Ferda Ozkinay Funda Tihminlioglu Funda Yagci Acar Gul Basaran Gul Kitapcioğlu Guray Saydam Gurer Budak Hakan Akbulut Hakan Aydin Hatice Durak Isİk Tuglular Ismet D. Gurhan Kamil Kumanlioglu Kemal Korkmaz Kevser Piskin Kezban Ulubayram Mehmet Ali Ozguven Mehmet Kantar Mehmet Sarikaya Murat Argon Murat Tombuloglu Mustafa Culha Mustafa Ozen Mustafa Selman Yavuz *Names are listed alphabetically. Nazan Cetingul Necdet Saglam Nezih Hekim Nezih Meydan Omer Ugur Perihan Unak Remziye Deveci Sabire Karacali Sacide Alsoy Altinkaya Savas Kansoy Seckin Cagirgan Serdar Ozcelik Serdar Turhal Serra A Kamer Suna Erdogan Suleyman Ali Tuncel S. Burcak Karaca Turkan Eldem Ufuk Gunduz Ulkem Yararbas Varol Pabuccuoglu Yavuz Anacak Yilmaz Capan Zehra Ozcan Zeynep Burak

Filiz Oner Adil Denizli Ahmet Ozet Ali Ugur Ural Ali Tuncel Arlin Kiremitci Aysel Yurtsever Aysegül Akgun Berrin Erdag Beste Atasoy Bulent Karabulut Can Ozen Candan Tamerler Cumhur Gunduz Dicle Guc

4 INVITED SPEAKERS Ruth Duncan (Cardiff University, UK) Simion Astilean (Babes - Bolyai University, Romania) Hayat Önyüksel (University of Illinois, Chicago, USA) Patrick Couvreur (Université Paris-Sud, France) Jorg Kreuter(Goethe Universitat Frankfurt, Germany) Francois Rossi (JRC, Italy) Bülent Özpolat (University of Texas, USA) Candan Tamerler (University of Washington, USA) David M. Goldenberg (Center for Molecular Medicine and Immunology, New Jersey, USA) Alexander Drzezga (Technische Universität München, Germany) Utkan Demirci (Harvard University and Massachusetts Institute of Technology) Mehmet Sarıkaya (USA) Hasan Korkaya (University of Michigan, USA) SCIENTIFIC PROGRAMME 7 th November, Thursday: International Symposium on Cancer Nanomedicine (ISCN) 15:00-17:00 Registration 17:00-18:00 ISCN Opening Ceremony 18:00-19:00 Plenary Lecture: Anticancer Nanomedicines: Opportunities and Challenges for Clinical Use Dr. Ruth Duncan (Cardiff University, UK) 19:00-20:00 Opening Cocktail 8 th November, Friday: International Symposium on Cancer Nanomedicine (ISCN) 8:45-10:30 Nanomedicine in Cancer Therapy Strategies Moderators: Dr. Erhan Gokmen, Dr. Volga Bulmus Anticancer Nanomedicine and Nanotheranostics Dr. Patrick Couvreur (Université Paris-Sud, FRANCE) Nanosystems for Overcoming Drug Resistance Dr. Hayat Onyuksel (University of Illinois, Chicago, USA) Nanovectors and sirna-based Gene Therapy of Cancer Dr. Bulent Ozpolat (University of Texas, USA) 10: Coffee Break :10 Challenges in Cancer Nanomedicine Moderators: Dr. Ruchan Uslu, Dr. Gurer Budak Drug Delivery to the Brain Accros the Blood-Brain Barrier Using Nanoparticles Dr. Jorg Kreuter (Goethe Universitat Frankfurt, GERMANY) Nanotoxicology Dr. Francois Rossi (European Comission Joint Research Centre, ITALIA) 12:10-13:30 Lunch Break Satellite Symposium

Goldenberg (Center for Molecular Medicine and Immunology, New Jersey, USA) Alexander Drzezga (Technische Universität München, Germany) Utkan Demirci (Harvard University and Massachusetts Institute of

5 SCIENTIFIC PROGRAMME 13:30-15:15 Targeted Nanosystems Moderators: Dr Kemal Baysal, TBA Advances in Antibody - Based Cancer Therapeutics Dr. David M. Goldenberg (Center for Molecular Medicine and Immunology, New Jersey, USA) Targeted Bioimaging Dr. Alexander Drzezga (Technische Universität München, Germany) Treatment of Acute Promyelocytic Leukemia by ATRA-based Targeted Therapy: The Prototype of Targeted Therapy in Cancer Dr. Bulent Ozpolat (University of TEXAS, USA) 15:15-15:45 Coffee Break 15:45-17:30 Nanotechnology for Detection and Therapy Moderators: Dr. Hakan Aydin, Dr. Burcak Karaca Plasmonic nanoparticles with multiple functionalities in nanomedicine (from Sensing to CancerTherapy) 17:30-18:30 20:00-24:00 Gala Dinner Dr. Simion Astilean (Babes - Bolyai University, ROMANIA) Nanoparticles for Theranostics Dr. Candan Tamerler (University of Washington, USA) Cancer Stem Cell Imaging and Targeting Dr. Hasan Korkaya (University of Michigan, USA) "Meet The Professor" Interactive Meetings 9 th November, Saturday: International Symposium on Cancer Nanomedicine ( ISCN) 09:00-10:10 Cancer Nanomedicine: Current Status and Future Expectations Moderator: Dr. Erdem Goker Targeted cancer therapies: Current status and future Expectations Dr. Bulent Karabulut (Ege University) Micro and Nano-scale Technologies for Applications in Medicine Dr. Utkan Demirci (Harvard University and Massachusetts Institute of Technology) 10:10-10:30 Coffee Break 10:30-12:00 Open Discussion Forum: Problems and Solutions in Cancer Medicine Moderators: Dr. Nezih Hekim, Dr. Ahmet Özet Expectations of Oncologists from Nanotechnology Dr. Hakan Akbulut, Dr. Gul Basaran, Dr. Ayfer Haydaroglu Expectations of Nanotechnologs from Oncology Dr. Mehmet Sarikaya, Dr. Hayat Onyuksel, Dr. Utkan Demirci 12:00-13:30 Lunch Break "Meet The Proffesor" Interactive Meetings Dr. Mehmet Sarikaya, Dr. Utkan Demirci, Dr. Bulent Ozpolat Dr. Candan Tamerler, Dr. Hasan Korkaya

Alexander Drzezga (Technische Universität München, Germany) Treatment of Acute Promyelocytic Leukemia by ATRA-based Targeted Therapy: The Prototype of Targeted Therapy in Cancer Dr.

6 SCIENTIFIC PROGRAMME 13:30-15:00 Hall A: Invited Oral Presentations Moderators: Dr. Volga Bulmus, Dr. Senem Demirci Chemistry and Physics of Nanoparticles for Medical Applications Dr. Serdar Ozcelik (Izmir Institute of Technology) 2.Design of MicroRNA Loaded Polymeric Nanoparticles for Treatment of Leukemia Dr. Ipek Ozcan (Ege University) 3. Tissue Engineered In Vitro 3D Tumor Models Dr. Aylin Sendemir-Urkmez (Bilkent University) 4. Nanoliposomes for Cancer Therapy: Preparation and Functionalization Dr. Rukan Genc (Bilkent University) 5. Nanosensing of Cancer Cell Receptors Dr. Memed Duman (Hacettepe University) 6. Development of anti-angiogenic antibodies for nanomedicine Dr. Berrin Erdag (TUBITAK, MAM) Hall B: Turkish Oncology Group (TOG) Meeting Moderators: Dr. Hakan Akbulut, Dr. Gul Basaran, Dr. Engin Ulukaya Project discussions 15:00-15:15 Coffee Break 15:15-17:00 Poster and Project Presentations Moderators: Dr. M. Sengun Ozsoz, Dr. Aysel Yurtsever 17:00-17:30 Coffee Break 17:30-18:00 Poster and Project Awards Closing Ceremony CONTACT Scientific Secreteriat Izmir Institute of Technology Department of Chemical Engineering Dr. Volga Bulmus Phone: Organization Secreteriat Dalya Tourism Congress & Organization Phone: Ext: 131 Fax: Address: 1427 Sok. No:19/B Kahramanlar / Izmir - TURKEY

Tissue Engineered In Vitro 3D Tumor Models Dr. Aylin Sendemir-Urkmez (Bilkent University) 4. Nanoliposomes for Cancer Therapy: Preparation and Functionalization Dr. Rukan Genc (Bilkent University) 5.

FINAL AND PERMANENT VERSION THURSDAY, FEBRUARY 17, 2011 DAY 1 (FRIDAY, MAY 6, 2011): Chairpersons: E. Özer (TR) - S.A.Raptis (GR)

FINAL AND PERMANENT VERSION THURSDAY, FEBRUARY 17, 2011 1 st TURKISH-HELLENIC POSTGRADUATE CONTINUOUS MEDICAL EDUCATION MEETING MAY 6-9, 2011, IZMIR, TURKEY DAY 1 (FRIDAY, MAY 6, 2011): Chairpersons: E.