Summer School 2011 Berlin SFB Transregio 19

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1 Summer School 2011 Berlin SFB Transregio 19 27th October 29th October 2011 Molecular Mechanisms and Consequences of Inflammatory Cardiomyopathy: State of the Art and Future Challenges

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3 Welcome Address Dear Colleagues and Friends Since nearly 8 years it is a sound tradition of the SFB/TR 19 to hold the international Summer School symposium with great success and popularity at one of the three locations Berlin, Greifswald and Tübingen of the SFB Transregio 19. It s now a great pleasure to invite you to attend the 2011 Summer School of the Sonderforschungsbereich Transregio 19: Inflammatory Cardiomyopathy Molecular Pathogenesis and Treatment. The SFB/TR 19 comprises a consortium of scientists from the Universities of Berlin, Greifswald and Tübingen. A special focus of the Summer School 2011 will be on Molecular Mechanisms and Consequences of Inflammatory Cardiomyopathy: State of the Art and Future Challenges. A characteristic feature of the SFB/TR 19 is the investigation of basic aspects of inflammatory cardiomyopathy (DCMi) in close connection with clinical questions. Leslie Cooper has highlighted in his recent report in the New England Journal of Medicine that viral and postviral myocarditis remain major causes of acute and chronic dilated cardiomyopathy leading to a substantial disease burden in the community. Accordingly and with respect to the major topic of the SFB/TR19 new aspects of the etiology and basic research of the mechanisms leading to inflammatory cardiomyopathy will be presented during the Summer School by international approved scientists. The SFB/TR19 Summer School is primarily intended for young scientists to encourage their interest and enthusiasm for research. We are looking very forward with great pleasure to this translational meeting within the exciting city of Berlin and to lively discussions promoting future research in this field. Thomas Bock and Reinhard Kandolf

4 Program of the Summer School 2011 at the RKI Thursday, :00 21:00 Get together at the RKI and Registration Berlin, Nordufer 20 Friday, :00 08:30 Registration 08:30 08:40 Opening Thomas Bock and Reinhard Kandolf Berlin und Tübingen 08:40 08:55 Address of Welcome of the Vice President of the Robert Koch Institute Lars Schaade, Vice President of the RKI RKI Session 1 Chair: Carsten Tschöpe and Paolo Di Nardo 09:00 09:30 Immunobiology of acute and chronic myocarditis 09:30 10:00 The cardiac fibroblast regulation of extracellular matrix production and cardiac inflammation Karin Klingel Diana Lindner 10:00 10:30 Risk factors of heart diseases Christa Scheidt Nave RKI UK Tübingen Charite Berlin 10:30 11:00 Break

5 Session 2 Chair: Blanche Schroen and Wolfgang Poller 11:00 11:30 Zoonotic infectious disease: implications for biodiversity conservation and global health 11:30 12:00 Novel therapeutic option in autoimmune cardiomyopathy 12:00 12:30 Engineered tissue strategies to mend the post inflammatory heart 12:30 14:15 Lunch Fabian Leendertz Gabriela Kania Paolo Di Nardo RKI Zürich, Swizerland Uni Tor Vergata Rome, Italy Session 3 Chair: Peter Michael Kloetzel and Maria Söderlund Venermo 14:15 15:00 Key Note 1: Viral myocarditis: State of the art and future challenges 15:00 15:30 Molecular genetic tools in diagnosis of cardiomyopathies H. Peter Schultheiss Hanns Georg Klein Charite Berlin München 15:30 15:45 Break 15:45 16:30 Visit of the Robert Koch Museum Session 4 Chair: Thomas Bock and Uwe Völker 16:30 17:00 Lifelong persistence of variant parvovirus DNA genomes 17:00 17:30 micrornas in cardiac inflammation and failure vis à vis of the great lecture hall Maria Söderlund Venermo Blanche Schroen University of Helsinki UK Maastricht 17:45 18:30 Key Note 2: NO ONE IS NAIVE: The relevance of heterologous immunity for viral infections Markus Cornberg MH Hannover 18:30 20:00 Transfer to Dinner 20:00 23:00 Dinner

6 Saturday, Session 5 Chair: Stephan Felix and Reinhard Kandolf 09:00 09:30 Magnetic resonance imaging (MRI) of inflamed myocardium using iron oxide nanoparticles 09:30 10:00 Significance of echocardiography for the diagnosis of inflammatory heart muscle diseases 10:00 10:30 Cardiovascular relevant Gi protein dependent functions Ali Yilmaz Mario Kasner Bernd Nürnberg Robert Bosch Stuttgart Charite Berlin UK Tübingen 10:30 11:00 Break Session 6 Chair: Carmen Scheibenbogen and H. Peter Schultheiss 11:00 11:30 Fishing for the genetic basis of cardiovascular disease Wolfgang Rottbauer UK Ulm 11:30 12:00 Cardiac Z disc signaling network Norbert Frey UK Kiel 12:00 12:20 Remarks for the members of the SFB TR19 H. Peter Schultheiss/ Wolfgang Poller 12:20 12:30 Closing Remarks Thomas Bock ca. 13:00 End of Summer School

7 Speakers and Chairs PD Dr. Lars Schaade, Vice President of the Robert Koch Institue, Berlin, Germany PD Dr. Markus Cornberg, Hannover Medical School, Germany Prof. Dr. Paolo, Di Nardo, University of Rome, Italy Prof. Dr. Stephan Felix, University of Greifswald, Germany Prof. Dr. Norbert Frey, University Medical Center Schleswig Holstein, Germany Prof. Reinhard Kandolf, University of Tuebingen, Germany Prof. Dr. Gabriela Kania, University of Zurich, Switzerland Dr. Mario Kasner, Charité Universitätsmedizin Berlin, Germany Dr. Hanns Georg Klein, Munich, Germany Prof. Karin Klingel, University of Tuebingen, Germany Prof. Dr. Peter Michael Kloetzel, Charité Universitätsmedizin Berlin, Germany Dr. Fabian Leendertz, Robert Koch Institue, Berlin, Germany Dr. Diana Lindner, Charité Universitätsmedizin Berlin, Germany Prof. Dr. Bernd Nürnberg, University of Tuebingen, Germany Prof. Dr. Wolfgang Poller, Charité Universitätsmedizin Berlin, Germany Prof. Dr. Wolfgang Rottbauer, University of Ulm, Germany Prof. Dr. Carmen Scheibenbogen, Charité Universitätsmedizin Berlin, Germany Dr. Christa Scheidt Nave, Robert Koch Institute, Berlin, Germany Prof. Dr. Blanche Schroen, University of Maastricht, Netherlands Prof. Dr. H. Peter Schultheiss, Charité Universitätsmedizin Berlin, Germany Prof. Dr. Maria Söderlund Venermo, University of Helsinki, Finland Prof. Dr. Carsten Tschöpe, Charité Universitätsmedizin Berlin, Germany Prof. Dr. Uwe Völker, University of Greifswald, Germany Dr. Ali Yilmaz, Robert Bosch Hospital Prof. Dr. Thomas Bock, Robert Koch Institue, Berlin, Germany

8 General Information Scientific and Organizing Committee: Prof. Dr. Thomas Bock, Robert Koch Institute, Berlin, Germany and Prof. Dr. Reinhard Kandolf, Molekulare Pathologie University of Tuebingen, Germany Phone +49 (0) Summer School Secretariat: Mrs. Francesca Smolinski Phone: +49 (0) Summer School Venue: Robert Koch Institute Nordufer Berlin, Germany Lecture Hall Summer School Organizing: Dr. Boris Ratsch Agnes Bryniok Maria Martin Francesca Smolinski Conference language is English The Summer School is sponsored by the Deutsche Forschungsgemeinschaft (DFG) and the Robert Koch Institute The Summer School is certified with 12 CME credits by the Ärztekammer Berlin

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