DWI: Physics and its applications in non-stroke brain pathologies

Transcription

1 DWI: Physics and its applications in non-stroke brain pathologies Poster No.: C-2752 Congress: ECR 2010 Type: Educational Exhibit Topic: Neuro Authors: S. Kanekar; Hershey, PA/US Keywords: DWI, Physics, Non-stroke applications DOI: /ecr2010/C-2752 Any information contained in this pdf file is automatically generated from digital material submitted to EPOS by third parties in the form of scientific presentations. References to any names, marks, products, or services of third parties or hypertext links to thirdparty sites or information are provided solely as a convenience to you and do not in any way constitute or imply ECR's endorsement, sponsorship or recommendation of the third party, information, product or service. ECR is not responsible for the content of these pages and does not make any representations regarding the content or accuracy of material in this file. As per copyright regulations, any unauthorised use of the material or parts thereof as well as commercial reproduction or multiple distribution by any traditional or electronically based reproduction/publication method ist strictly prohibited. You agree to defend, indemnify, and hold ECR harmless from and against any and all claims, damages, costs, and expenses, including attorneys' fees, arising from or related to your use of these pages. Please note: Links to movies, ppt slideshows and any other multimedia files are not available in the pdf version of presentations. Page 1 of 5

2 Learning objectives 1. To understand the relevant physical principles of the diffusion-weighted imaging (DWI) for the radiologist. 2. To highlight the applications and usefulness of DWI in non-stroke pathologies of the brain. Images for this section: Page 2 of 5

3 Fig. 1: DWI---Physics and its applications in non-stroke brain pathologies. Page 3 of 5

4 Background DWI provides the viability information of the brain. Role of DWI in stroke has been well established due to its capability to diagnose stroke as early as mts From its introduction from mid 1990's, clinical application have been widespread. Last few years DWI has found to be increasingly useful in diagnoses of various non-stroke intra/ extraaxial pathologies of brain. Restricted diffusion though once considered specific for stroke, can also be seen in various other pathologies ranging from infection, neoplasms, trauma, blood products to demyelinating condition. Imaging findings OR Procedure details To understand application and usefulness of DWI sequence, knowledge of physics and principle behind this sequence is mandatory. In the first half of this exhibit we simplify the physics and the principle of DWI. In the second half, we show various pathologies where DWI can aid in reaching the specific diagnosis. We categorize these pathologies into: hemorrhagic and non-hemorrhagic stroke, infection, trauma, hemorrhage, demyelination, and extra and intra-axial neoplasm. Conclusion 1. We make understand the relevant physics and principles of the DWI to the practicing radiologist. 2. DWI has an established role in imaging of stroke. In this exhibit we highlight its importance in diagnosis of non-stroke pathologies of brain. We highlight this concept with illustrations. 3. This exhibit will be core learning tool for DWI sequence. Personal Information References Page 4 of 5

5 1. Diffusion-weighted MR Imaging of the Brain Radiology 2000; 217: 331. Pamela W. Schaefer, P. Ellen Grant, and R. Gilberto Gonzalez 2. Diffusion MRI: precision, accuracy and flow effects. NMR Biomed 1995; 8: Conturo TE, McKinstry RC, Aronovitz JA, Neil JJ. 3. MR imaging of high-grade cerebral gliomas: value of diffusion-weighted echoplanar pulse sequences. AJR Am J Roentgenol 1994; 162: Tien R, Felsberg G, Friedman H, Brown M, MacFall J 4. Diffusion and perfusion magnetic resonance imaging: applications to functional MRI New York, NY: Raven, Le Bihan D 5. Basic principles of diffusion-weighted imaging European Journal of Radiology 45 (2003) Roland Bammer Page 5 of 5