Pancreatic masses: What is there besides cancer

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1 Pancreatic masses: What is there besides cancer Poster No.: C-0201 Congress: ECR 2010 Type: Educational Exhibit Topic: Abdominal Viscera (Solid Organs) Authors: M. A. Portilha, C. Ruivo, I. Santiago, M. Armas, B. Graça, F Alves, F. Caseiro-Alves ; Coimbra/PT, Aveiro/PT, Funchal/PT Keywords: pancreatic, mass, mimic DOI: /ecr2010/C-0201 Any information contained in this pdf file is automatically generated from digital material submitted to EPOS by third parties in the form of scientific presentations. References to any names, marks, products, or services of third parties or hypertext links to thirdparty sites or information are provided solely as a convenience to you and do not in any way constitute or imply ECR's endorsement, sponsorship or recommendation of the third party, information, product or service. ECR is not responsible for the content of these pages and does not make any representations regarding the content or accuracy of material in this file. As per copyright regulations, any unauthorised use of the material or parts thereof as well as commercial reproduction or multiple distribution by any traditional or electronically based reproduction/publication method ist strictly prohibited. You agree to defend, indemnify, and hold ECR harmless from and against any and all claims, damages, costs, and expenses, including attorneys' fees, arising from or related to your use of these pages. Please note: Links to movies, ppt slideshows and any other multimedia files are not available in the pdf version of presentations. Page 1 of 52

2 Learning objectives To illustrate the radiological features of the most frequent pseudotumoral pancreatic conditions. To describe the characteristics that may be useful in the differential diagnosis with primary pancreatic cancer. Background Although the advances in imaging have increased the diagnosis of pancreatic masses, their correct identification as a nonneoplastic process is still difficult. Approximately 5% to 10% of pancreatectomies performed with the clinical diagnosis of pancreatic cancer prove on microscopic evaluation to be pseudotumors. Pancreatic pseudotumors represent multiple distinct categories of lesions characterized by a benign enlargement of the gland, which clinically resembles a true neoplasm so closely as to often be mistaken for such. Imaging findings OR Procedure details Page 2 of 52

3 Fig.: 16 References: M. A. Portilha; Radiology, Hospitais da Universidade de Coimbra, Coimbra, PORTUGAL Page 3 of 52

4 Fig.: fig.1. References: M. A. Portilha; Radiology, Hospitais da Universidade de Coimbra, Coimbra, PORTUGAL Page 4 of 52

5 Fig.: fig6 References: M. A. Portilha; Radiology, Hospitais da Universidade de Coimbra, Coimbra, PORTUGAL Page 5 of 52

6 Fig.: fig.4 References: M. A. Portilha; Radiology, Hospitais da Universidade de Coimbra, Coimbra, PORTUGAL Page 6 of 52

7 Fig.: fig.5 References: M. A. Portilha; Radiology, Hospitais da Universidade de Coimbra, Coimbra, PORTUGAL D Page 7 of 52

8 Fig.: fig.1. References: M. A. Portilha; Radiology, Hospitais da Universidade de Coimbra, Coimbra, PORTUGAL Page 8 of 52

9 Fig.: fig.2 References: M. A. Portilha; Radiology, Hospitais da Universidade de Coimbra, Coimbra, PORTUGAL Page 9 of 52

10 Fig.: fig.1. References: M. A. Portilha; Radiology, Hospitais da Universidade de Coimbra, Coimbra, PORTUGAL Page 10 of 52

11 Fig.: fig.3 References: M. A. Portilha; Radiology, Hospitais da Universidade de Coimbra, Coimbra, PORTUGAL Discuss the broad array of entities that may mimic primary pancreatic neoplasia, including normal anatomic variants, inflammatory and infectious diseases of the pancreas, vascular lesions and disease in surrounding structures. Images for this section: Page 11 of 52

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51 Conclusion Pancreatic pseudotumors are a polymorphous category of lesions in which a correct preoperative diagnosis is sometimes difficult to achieve. Awareness of the imaging spectrum of pseudotumoral pancreatic conditions is very important, in order to initiate the appropriate lesion-specific work-up and treatment, as well as to avoid unnecessary tests or procedures, including surgery. Pncreatic pseudotumors are a polymorphous category of lesions in which a correct preoperative diagnosis is sometimes difficult to achieve. Awareness of the imaging spectrum of pseudotumoral pancreatic conditions is very important, in order to initiate the appropriate lesion-specific work-up and treatment, as well as to avoid unnecessary tests or procedures, including surgery. Personal Information Maria Antónia Portilha Hospitais da Universidade de Coimbra Coimbra / PORTUGAL References Brasca LE, Zanello A, De Gaspari A, et al. Intrapancreatic accessory spleen mimicking a neuroendocrine tumor: magnetic resonance findings and possible diagnostic role of different nuclear medicine tests. Eur Radiol 2004;14: Hayward I, Mindelzun RE, Jeffrey RB. Intrapancreatic accessory spleen mimicking pancreatic mass on CT. J Comput Assist Tomogr 1992; 16: Grand DJ, Sobin LH, Fishman EK. Enteric duplication cyst of the pancreas: CT findings. Crit RevComput Tomogr 2004; 45: McCullough KM. Duodenal diverticulum simulating a pancreatic mass on computed tomography. Australas Radiol 1991; 35: Page 51 of 52

52 Macari M, Lazarus D, Israel G, Megibow A. Duodenal diverticula mimicking cystic neoplasms of the pancreas: CT and MR imaging findings in seven patients. AJR Am J Roentgenol 2003; 180: Berrocal T, Torres I, Gutierrez J, Prieto C, del Hoyo ML, Lamas M. Congenital anomalies of the upper gastrointestinal tract. RadioGraphics 1999; 19: Johnson PT, Outwater EK. Pancreatic carcinoma versus chronic pancreatitis: dynamic MR imaging. Radiology 1999; 212: Ichikawa T, Sou H, Araki T, et al. Duct-penetrating sign at MRCP: usefulness for differentiating inflammatory pancreatic mass from pancreatic carcinomas. Radiology 2001; 221: Hayashi H, Matsuyama S, Edakuni G, et al. Focal pancreatic hemorrhage mimicking pancreas carcinoma with lymph node metastasis. J Hepatobiliary Pancreat Surg 2002; 9: Herman P, Machado MC, Salem MZ, Jukemura J, Montagnini AL, Pinotti HW. Mesenteric artery aneurysm simulating a tumor in the head of the pancreas: report of a case. Pancreas 1996; 13: LeVan TA, Clifford S, Staren ED. Castleman's tumor masquerading as a pancreatic neoplasm. Surgery 1989; 106: Page 52 of 52

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