IBS BOLOGNA DAYS 2016 New insights for a better management of irritable bowel syndrome 8-10 June 2016 Bologna, Italy

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1 IBS BOLOGNA DAYS 2016 New insights for a better management of irritable bowel syndrome 8-10 June 2016 Bologna, Italy Dear Colleagues, I am delighted to welcome you to IBS Bologna Days The purpose of the meeting is to provide an interactive forum and presentation of up to date Lectures on IBS. The Scientific Committee chaired by Professor Vincenzo Stanghellini, has prepared an exciting program covering all aspects of IBS, including the newly released Rome IV criteria, algorithms, epidemiology, overlap with comorbid conditions, the role of genetic factors, diet, microbiota, inflammation and infection, diagnosis and biomarkers, as well as current and future therapeutic approaches. Our aim is to provide the current views as well as a look to the future in the rapidly advancing field of IBS. To do so, we have designed a format based on State of the Art and Keynote Lectures given by internationally renowned leading experts as well as Hot of the Press papers on original data presented by young investigators. We hope that the meeting will promote friendship, exchange of ideas, opinions, discussion of cases and development of research projects that would ultimately advance the field and improve the management of our patients. I hope you will enjoy IBS Bologna Days 2016 program as well as the city of Bologna with its ancient University (A.D. 1088), a long history and excellent cusine. Giovanni Barbara Chair, IBS Bologna Days 2016 Scientific Committee: Vincenzo Stanghellini, (Chair) Enrico Corazziari, Maura Corsetti, Cesare Cremon Wednesday June 8 th Opening Ceremony Welcome Giovanni Barbara and Vincenzo Stanghellini, University of Bologna, Italy Francesco Ubertini, Rector, University of Bologna, Italy Fabrizio De Ponti, President, School of Medicine, University of Bologna, Italy Mario Cavalli, General Director, St. Orsola-Malpighi Hospital, Bologna Italy Marco Zoli, Director, Department of Medical and Surgical Sciences, University of Bologna, Italy Franco Bazzoli, Director Department of Gastroenterology, University of Bologna, Italy Why centenarians are centenarians? and what about their offspring and family members? Claudio Franceschi (Italy) Choral perfomance Welcome cocktail

2 ADVANCED PRELIMINARY PROGRAM Thursday June 9 th 7.30 Registration Royal Carlton Hotel Session I - Rome IV Criteria and Clinical Scenarios Chairs: Robin Spiller (UK), Franco Bazzoli (Italy) Rome IV Symposium Rome IV Criteria: what s new? Douglas Drossmann (USA) IBS-C and chronic constipation: marriage or divorce? Enrico Corazziari (Italy) Rome IV diagnostic algorithms for IBS Jan Tack (Belgium) IBS symptoms in IBD in remission: is inflammation the key? Thierry Piche (France) Geographical, cultural and environmental factors Kok Ann Gwee (Singapore) Break Session II - Pathophysiology Chairs: Michael Camilleri (USA), Gabrio Bassotti (Italy) Psyche in IBS: all in the brain after all? Lukas Van Oudenhove (Belgium) Is IBS written in the genes? Mauro D Amato (Spain) Sensory-motor function and IBS: What s new Maura Corsetti (Belgium) Gas bloating and distension: a diet, microbiota, sensory-motor interplay? Fernando Azpiroz (Spain) Lunch Session III Microenvironment Factors Chairs: Antonio Gasbarrini (Italy), Giovanni Barbara (Italy) Gut microbiota: what the clinician should know? Patrizia Brigidi (Italy)

3 14.55 Microbiota and IBS: what is new? Uday Ghoshal (India) Keynote Lecture Gut microbiota - brain interactions: from basic to clinical science Stephen M. Collins (Canada) New insights on serotonin Robin Spiller (UK) Neuro-immune interactions Guy Boeckxtaens (Belgium) Break Session IV Hot Off the Press Chairs: Guido Basilisco (Italy), Massimo Bellini (Italy) Link between microbiota signatures and IBS severity Julien Tap (Sweden) Zonulin, permeability and IBS Maria Raffaella Barbaro (Italy) Epithelial barrier dysfunction in IBS Cristina Martinez (Spain)

4 Friday June 10 th Session V Management I: Diet, Probiotics and Biomarkers Chairs: Jan Tack (Belgium), Rosario Cuomo (Italy) Tandem Talk on FODMAPS PRO: Robin Spiller (UK) CON: Hans Tornblom (Sweden) Gluten Sensitivity: starting to tease apart a different entity? Umberto Volta (Italy) Keynote Lecture Experimental and diagnostic value of novel biomarkers Michael Camilleri (USA Probiotics: plural activities for a multifaceted pathogenesis TBD Probiotics and child functional gut disorders Annamaria Staiano (Italy) Break Session VI Management II: Pharmacological Agents Chairs: TBD, Carmelo Scarpignato (Italy) Placebo, precebo and nocebo? Paul Enck, (Germany) Secretagogues: secretion, pain modulation and beyond TBD Non-absorbable antibiotics: targeting dysbiosis and beyond Herbert DuPont (USA) Therapeutic targeting of bile acids Michael Camilleri (USA) New therapeutic perspectives Jan Tack (Belgium) Lunch Session VII Hot Off the Press and Pilot data from RCTs Chairs: Giuseppe Chiarioni (Italy), Roberto De Giorgio (Italy) Low FODMAP diet is better than low FODMAP gluten free diet in IBS Daria Piacentino (Italy) B. longum NCC: a RCT shows improvement of depression and emotional reactivity in IBS Maria Inès Pinto-Sanchez (Canada)

5 15.10 Kiwi fruit and IBS-C: rationale and evidence Juliet Ansell (New Zealand) L. casei DG: a RCT on IBS symptoms and microbiota Cesare Cremon (Italy) Concluding remarks Giovanni Barbara (Italy)

6 Endorsed by Supported by PLATINUM SPONSOR Alfa Wassermann GOLD SPONSOR Allergan Zespri SILVER SPONSOR Sofar SPONSOR Norgine Pegaso Yakult Zambon

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