Magnetic Resonance Techniques in Multiple Sclerosis

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1 Università Vita-Salute San Raffaele Neuroimaging Research Unit Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute and Vita - Salute San Raffaele University Magnetic Resonance Techniques in Multiple Sclerosis Eighteenth Advanced Course SCIENTIFIC PROGRAM CME ACCREDITED COURSE San Raffaele Scientific Institute Via Olgettina, Milano, Italy

2 ORGANIZING SECRETARIAT Biomedia srl Monica Arosio Via L. Temolo Milano Tel. 02/ Fax 02/ Biomedia utilizza un Sistema di Gestione Qualità Certificato per progettazione ed erogazione di eventi di formazione residenziale e a distanza e di servizi organizzativi per corsi e convegni

3 MAGNETIC RESONANCE TECHNIQUES IN MULTIPLE SCLEROSIS Eighteenth Advanced Course SCIENTIFIC DIRECTION: M. Filippi G. Comi SCIENTIFIC SECRETARIAT: M.A. Rocca ORGANIZING SECRETARIAT: G. Nyitrai L. Zonca FACULTY MEMBERS Maria P. Amato (Firenze, Italy) John Ashburner (London, UK) Marco Battaglini (Siena, Italy) Ralph Benedict (Buffalo, USA) Giancarlo Comi (Milan, Italy) John De Luca (West Orange, USA) Nicola De Stefano (Siena, Italy) Christian Enzinger (Graz, Austria) Arman Eshaghi (Teheran, Iran) Monica Falautano (Milan, Italy) Massimo Filippi (Milan, Italy) Jeroen J. Geurts (Amsterdam, Netherlands) Roland Henry (San Francisco, USA) Mark A. Horsfield (Leicester, UK) Mark Jenkinson (Oxford, UK) Carsten Lukas (Bochum, Germany) Maria A. Rocca (Milan, Italy) James Sumowski (West Orange, USA) Koen Van Leemput (Boston, USA) Alex P. Zijdenbos (Montreal, Canada) 1

4 Programme 19 March Welcome, introductory remarks G. Comi Program overview M. Filippi Atrophy quantification in MS: from clinical needs to methodological pitfalls. Towards the identification of the best method? SESSION I - THE CLINICAL PERSPECTIVE Chairs: M. Filippi, G. Comi What structures should be measured? Whole brain vs WM/GM segmentation? N. De Stefano Deep GM nuclei: a simple, clinically meaningful measure? R. Benedict Spinal cord atrophy: the missing measure? C. Lukas Coffee break SESSION II - METHODOLOGICAL CONSIDERATIONS Chairs: N. De Stefano, R. Henry How to measure: accuracy, reproducibility, sensitivity to changes M.A. Horsfield T1 lesion refilling: how and why? M. Battaglini Lunch 2

5 Programme SESSION III - METHODS AND SOFTWARES: CROSS-SECTIONAL AND LONGITUDINAL APPLICATIONS, PROS AND CONS I Chairs: M.A. Rocca, A. Eshaghi FSL: SIENA, SIENAx, FIRST M. Jenkinson SPM J. Ashburner Freesurfer K.V. Leemput Afternoon tea CIVET A.P. Zijdenbos ANTs A. Eshaghi SESSION IV - METHODS AND SOFTWARES: CROSS-SECTIONAL AND LONGITUDINAL APPLICATIONS, PROS AND CONS II Chairs: R. Benedict, M.A. Horsfield How to choose a method and its implementation R. Henry SESSION V - ROUND TABLE SUMMING UP AND CONCLUSIONS Chair: M. Filippi Discussants: N. De Stefano, R. Benedict, C. Lukas, M.A. Horsfield, R. Henry 3

6 Programme 20 March Introduction G. Comi Imaging cognitive dysfunction in MS SESSION VI - THE CLINICAL PERSPECTIVE Chairs: M. Falautano, J. Sumowski Neuropsychological profiles in MS: from cognitive relapse to dementia J. De Luca Cognitive assessment: towards a unified evaluation M.P. Amato Coffee break SESSION VII - THE IMAGING PERSPECTIVE Chairs: J. De Luca, M.P. Amato WM lesions and damage: just a disconnection syndrome? C. Enzinger GM lesions and damage: do they explain the whole story? J.J. Geurts Plasticity: what is the evidence? M.A. Rocca Brain reserve and cognitive reserve: where are we going? J. Sumowski Concluding remarks M. Filippi Farewell cocktail 4

7 General Information REGISTRATION Registration is free and includes admission to scientific sessions, conference materials, coffee breaks, lunch and certificate of attendance. HOW TO REGISTER All participants are kindly recommended to register via the online registration form at CONTINUING MEDICAL EDUCATION (ECM only for Italian participants) The event addresses to the disciplines of Neurology, Neurophysiopathology, Neuroradiology. In order to obtain credits, participants must attend the full educational programme (100% of the meeting) and pass the final learning test available on line on the site CERTIFICATE OF ATTENDANCE A certificate of attendance will be available to each participant at the end of the meeting OFFICIAL LANGUAGE English. Simultaneous translation service is not provided. HOTEL ACCOMMODATION In case of accomodation please contact: Biomedia Travel di Biomedia srl Via L. Temolo, Milano Tel.: 02/ Fax: 02/ CONGRESS VENUE San Raffaele Scientific Institute - Aula San Raffaele (c/o Direzione Sanitaria) Via Olgettina, Milano, Italy HOW TO REACH THE VENUE Motorways: San Raffaele Congress Centre can be reached by all motorways, following the direction "Tangenziale Est" (East ring road) till Cascina Gobba exit. Subway: San Raffaele Congress Centre is connected to Milan by green subway line. The subway stop is Cascina Gobba. Railway: Milano Central Railway Station is connected to San Raffaele Congress Centre by subway (green line). Airports: Malpensa Airport (50 km) and Linate Airport (5km) are connected to San Raffaele Congress Centre by railway, bus or taxi. 5

8 Magnetic Resonance Techniques in Multiple Sclerosis Eighteenth Advanced Course Unrestricted Educational Grant

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