Alicante, Spain April 23-25, Exhibition Invitation for the Industry

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1 Alicante, Spain April 23-25, Exhibition Invitation for the Industry Last Update: May 30, 2014

2 Dear Friends and Colleagues, Following the success of our 5 previous IVI Congresses, we are pleased to invite you to the 6th IVI International Congress to be held in Alicante, Spain, April 23-25, Our aim is to continue providing top-level reproductive medicine congresses, addressing cutting edge topics in this continuously evolving field of human reproduction and offering the most reputable international speakers available. Alicante is a port city located on the Mediterranean Sea. It is a city of great historical and cultural importance, example of this, the emblematic Santa Barbara Castle, built in the nineteenth century, and from which it is able to see the whole city. Furthermore, Alicante offers superb beaches that make it a perfect place to relax and get the energy that the sun and the sea breeze bring. The Mediterranean climate and regional food offer a wide variety of possibilities to enjoy your stay. We look forward to welcoming you to the 6th IVI International Congress! Sincerely, Prof. Antonio Pellicer Honorary Presidents Prof. José Remohí

reputable international speakers available. Alicante is a port city located on the Mediterranean Sea.

3 Scientific Program THURSDAY, APRIL 23, :00-17:00 Session 1 OVARIAN STIMULATION 15:00-15:30 Ovarian stimulation in 2015: Are we working in the right way? Bart Fauser, The Netherlands 15:30-16:00 Activation of dormant ovarian follicles to generate mature eggs. Hippo signaling disruption and AKT stimulation of ovarian follicles Kazuhiro Kawamura, Japan 16:00-16:30 Single embryo transfer with aneuploidy screening improves outcomes after in vitro fertilization: Obstetrical and neonatal outcomes Richard Scott, USA 16:30-17:00 Changing the paradigms in ovarian stimulation: What can we learn from luteal-phase ovarian simulation? Yanping Kuang, China 17:00-17:30 Coffee Break 17:30-19:45 Session 2 SURGERY 17:30-18:00 New aspects of uterine fibroid treatment in human reproduction Daniela Galliano, Spain 18:00-18:30 Endometriosis relates infertility: is it always necessary to operate endometriomas? Charles Chapron, France 18:30-19:00 Routine diagnostic hysteroscopy in 2015 Stefano Bettocchi, Italy 19:00-19:45 Debate: Is there a place for autoimmunity-thrombophilia testing in infertility patients? Yes: Diana Alecsandru, Spain No: Nicholas S. Macklon, UK 19:45-21:00 Welcome Reception

Hippo signaling disruption and AKT stimulation of ovarian follicles Kazuhiro Kawamura, Japan 16:00-16:30 Single embryo transfer with aneuploidy screening improves outcomes after in vitro

4 Scientific Program FRIDAY, APRIL 24, 2015 Parallel Sessions 08:30-10:30 Session 3a ENDOMETRIOSIS 08:30-09:00 Diagnosis of endometriosis in the 21 st Century Linda Giudice, USA 09:00-09:30 Medical treatment of symptoms: what have we learned? Paolo Vercellini, Italy 09:30-10:00 Is the endometrium of women with endometriosis different? Thomas D'Hooghe, Belgium 10:00-10:30 Does endometriosis affect ART results? Pedro Barri, Spain Hall B Parallel Sessions 08:30-10:30 Session 3b TOWARDS 100% SAFE ART LABS 08:30-09:00 Basic concepts of risk management and risk assessment applied to assisted reproduction laboratories Dominique de Ziegler, France 09:00-09:30 Protocols for tracking and witnessing samples and patients in ART María José de los Santos, Spain 09:30-10:00 Risk and risk management in the cryopreservation of reproductive cells and tissues Mathew Tomlinson, UK 10:00-10:30 Preconceptional genetic testing: Towards newborns free of genetic diseases? Nicolás Garrido, Spain 10:30-11:00 Coffee Break

Thomas D'Hooghe, Belgium 10:00-10:30 Does endometriosis affect ART results?

5 Scientific Program FRIDAY, APRIL 24, 2015 Parallel Sessions 11:00-13:00 Session 4a REGENERATIVE MEDICINE 11:00-11:30 Spermatogonial stem cell transplantation for male fertility preservation Kyle Orwig, USA 11:30-12:00 Mechanism and reconstitution in vitro of germ cell development in mammals Mitinori Saitou, Japan 12:00-12:30 Endometrial regeneration: Stem cell therapy in Asherman Syndrome and Atrophic Endometrium Xavier Santamaria, Spain 12:30-13:00 Uterine transplantation: Mats Brännström, Sweden Hall B Parallel Sessions 11:00-13:30 Session 4b PROCEDURES IN ANDROLOGY AND IVF LABS WHICH INFLUENCE THE ART SUCCESS 11:00-11:30 Biomarkers of embryo viability David Gardner, Australia 11:30-12:00 Evidence-based embryo selection techniques and methodologies Markus Montag, Germany 12:00-12:30 Nurturing and improving quality of oocytes in the IVF laboratory Laura Rienzi, Italy 12:30-13:00 Ways of selecting the right sperm for ART Con Mallidis, Germany 13:00-13:30 Micro-TESE to improve ART outcomes in severe male factor Craig Niederberger, USA 13:00-14:00 Lunch Break 14:00-16:00 Session 5 HOW TO IMPROVE OUR CLINICAL RESULTS IN IVF 14:00-14:30 Complete chromosome screening (CCS) of embryos: How, when & to whom? Carmen Rubio, Spain 14:30-15:00 Diagnosis and improvement of the endometrial factor: Facts and fallacies Carlos Simón, Spain 15:00-15:30 Fresh Embryo Transfer, Deferred Embryo Transfer or Personalized Embryo Transfer... That is the question Nicholas S. Macklon, UK 15:30-16:00 Embryo Vitrification: clinical state of the art Ana Cobo, Spain 16:00-16:30 Coffee Break 16:30-17:30 Clinical & Basic Research Awards Ceremony

and Atrophic Endometrium Xavier Santamaria, Spain 12:30-13:00 Uterine transplantation: Mats Brännström, Sweden Hall B Parallel Sessions 11:00-13:30 Session 4b PROCEDURES IN ANDROLOGY AND IVF LABS

6 Scientific Program SATURDAY, APRIL 26, :30-10:30 Session 6 FERTILITY PRESERVATION 08:30-09:00 Current status of fertility preservation in clinical setting Juan Antonio García-Velasco, Spain 09:00-09:30 New insights in ovarian stimulation and its application in infertility preservation Dror Meirow, Israel 09:30-10:00 Ovarian tissue freezing: state of the ART Claus Yding Andersen, Denmark 10:00-10:30 Debate: All women beyond 38 years of age should freeze their oocytes Yes: Linda Giudice, USA No: Yanping Kuang, China 10:30-11:00 Coffee Break 11:00-13:00 Session 7 FUTURE PERSPECTIVE 11:00-11:30 New infertility treatments of patients with primary ovarian insufficiency Kazuhiro Kawamura, Japan 11:30-12:00 Bioengineering the human uterus Irene Cervelló, Spain 12:00-12:30 The maternal origins of adult disease - The womb may be more important than the home Felipe Vilella, Spain 12:30-13:00 Preventing genetic diseases Julio Martín, Spain

10:00-10:30 Debate: All women beyond 38 years of age should freeze their oocytes Yes: Linda Giudice, USA No: Yanping Kuang, China 10:30-11:00 Coffee Break 11:00-13:00 Session 7 FUTURE PERSPECTIVE

7 Exhibition An exhibition will be held in conjunction with the Congress. The exhibition floorplan is designed to maximize exposure to the participants. All lunches and coffee breaks will be held in the exhibition area. Exhibition space will be available on a first-come, first-served basis. Exhibition space will be available at 420 per sq.m. The minimum booth size is 2x3 sq.m. Please visit to view the exhibition floorplan. Exhibition space rental is priced according to size (per sq.m) and includes: Net stand area Company profile in Supporters' Booklet Company logo in Supporters' Booklet Two exhibitor registrations Exhibitors Manual General cleaning of public areas Venue security Stand equipment and additional services may be ordered by means of the forms in the Exhibitors Manual: Furniture, partition walls, carpets, telephone and data lines, electricity, stand cleaning, exhibitors' insurance, logistics, etc. General Information Venue Auditorio de la Diputación de Alicante ADDA Paseo de Campoamor s/n Alicante Tel Language English is the official language of the Congress Simultaneous translation will be available in Spanish Congress Organizer and Sponsorship / Exhibition Contact: 53, Rothschild Boulevard, PO Box 68 Tel Aviv, 61000, Israel Tel: Fax: Elda@comtecmed.com

m. Please visit www.comtecmed.com/ivi to view the exhibition floorplan. Exhibition space rental is priced according to size (per sq.

8 General Information Liability and Insurance The Congress Organizer cannot accept liability for personal accidents loss of or damage of private property of participants, either during or indirectly arising from the IVI Congress. Participants are advised to issue their own personal travel and health insurance for their trip. Terms and Conditions Support items are allocated on a first-come, first-served basis All support and exhibition prices quoted are in and are subject to VAT All payments must be received before the beginning of the Congress. Should the company fail to make the payment prior to the commencement of the Congress, the Organizer saves the right to cancel the company s participation and benefits. Time slot allocation will be based on level of support and approval from the Organizing Committee It is the responsibility of the supporters and exhibitors to comply with the regulations of the local authorities, EFPIA (European Federation of Pharmaceutical Industries & Associations) org and IFMPA (International Federation of Pharmaceutical Manufacturers & Associations) www. ifpma.org Code of Practice on the Promotion of Medicines. The Congress Organizer reserves the right to accept or decline offers of support and application for exhibition space The Congress Organizer reserves the right to amend the published floorplan should it be deemed necessary for the benefit of the exhibition and the Congress as a whole Please note that the Congress Organizer must approve all exhibition stand designs All benefits: (logo, profile, insert, advertisement and registration) that are mentioned as part of the Supporter /Exhibitor packages are to be provided as per Comtec specifications and deadlines to ensure maximum exposure at the Congress. Hermes & Merkur is the sole logistic supplier for the IVI Congress. All materials sent directly to the venue (not via our logistic agent AKA Hermes) will not be under COMTECMED's responsibility. We are not liable if the shipment does not arrive due to costumes clearness issues or any other delays that might occur.

Terms and Conditions Support items are allocated on a first-come, first-served basis All support and exhibition prices quoted are in and are subject to VAT All payments must be received before the

PROGRAM GENETIC AND EPIGENETIC ANALYSES OF HUMAN EMBRYOS: PAST, PRESENT AND FUTURE

PROGRAM GENETIC AND EPIGENETIC ANALYSES OF HUMAN EMBRYOS: PAST, PRESENT AND FUTURE PROGRAM Thursday, September 17 h 15.00 I SESSION GENETIC AND EPIGENETIC ANALYSES OF HUMAN EMBRYOS: PAST, PRESENT AND FUTURE Chairmen: Carlo Flamigni (Bologna, Italy) - Sebastiano Bianca (Catania, Italy)