Resources for Modern Methods
|
|
|
- Georgia Augusta Hubbard
- 8 years ago
- Views:
Transcription
1 Resources for Modern Methods Experiences and Results Department for Environment and Energy Basel-City (AUE) Steffen Ruppe*, Dorrit Griesshaber*, Ingrid Langlois*, Jan Mazacek*, Matthias Ruff #, Martin Loos #, Heinz Singer # *Department for Environment and Energy Basel-City, Switzerland # Eawag: Swiss Federal Institute of Aquatic Science and Technology, Switzerland Kanton Basel-Stadt
2 Department for Environment and Energy Basel (AUE) The first out of seven Rhine monitoring stations is located near Basel, in Weil am Rhein. operated by AUE funded by the Federal Office for Environment (BAFU), Switzerland and the Ministry of the Environment, Sector Climate and Energy, Germany, Baden- Württemberg All samples from this station were analyzed by the AUE laboratory. Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 2
3 Resources for Modern Methods What do we need? LCMS-method measuring relevant targets at very low concentration ranges and detecting non-target substances How do we get there? In July 2009 a project started with the Eawag as scientific partner. 2011: approximately 300 substances were measured 2012: introduction of software EnviMass 1 (Martin Loos, Eawag) 2014: implementation of software EnviMass 2 method development took almost 4 years, primarily due to the missing software link Detection method and analysis software are critical factors for optimal use of resources. Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 3
4 Daily Analytical Strategy Using LC/MS-Orbitrap SPE (multiphase cartridges), 140 internal standards, measurements with a mass resolution of (+MS/MS-fragments) Target List (310) EnviMass Non-Target Priority Substances 50 Targets Manually integrated Semiquan. procedure Screening for relevant masses Trend detection Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 4
5 Priority Substance - obvious application periods in the spring and fall - daily measurements are important to detect violations of alarm limits and to enable estimations of chemical loads in the Rhine in this example, two days contributed 25 % of the annual Isoproturon load in 2013 Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 5
6 Priority Substance Aliskiren: originates from human usage (background level) and industrial production (peaks) dilution effects due to higher discharge can be observed Tizanidin: origin from industrial discharge was verified Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 6
7 Daily Analytical Strategy Using LC/MS-Orbitrap EnviMass Priority substances 50 Targets Target-List (310) Non-Target x calibration x semi-quantification x automated processing peak picking recalibration/alignment componentization prioritization EnviMass2 Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 7
8 Non-Target Screening: Mass (M+H + ) EnviMass2 computes a time series analysis comparing a current sample with last year s data set prioritization is based on a statistical method highlighting mass traces with increasing intensity EnviMass2 (July February 2014, including incident on ) ChemSpider search resulted in nearly 2000 suggestions for possible molecular formulas Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 8
9 Non-Target Screening: 2-Phenyl-2-(2-piperidin)acetamid The compound was identified knowing who discarded the substance and in cooperation with the company in question. 600 kg of the Ritalin reagent were discharged Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 9
10 Non-Target Screening: Mass (M-H - ) 13 C => 7 Carbon 15 N => 4 Nitrogen Mass resolution provide isotop distribution C7H2N4? mass accuracy < 2 ppm ChemSpider search resulted in only two suggestions due to the unusual elemental composition Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 10
11 Non-Target Screening: Mass (M-H - ) 13 C => 7 Carbon BW- 15 Holidays N => 4 Nitrogen taking the intensity profile and the timing of summer holidays in Switzerland and Germany into account, one potential pollution region is singled out discharging company was identified and provided the AUE laboratory with their reference standard Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 11
12 Non-Target Screening: Tetracarbonitrilpropen - nonessential by-product - not further monitored it poses a permanent pollution - concentration ranges from 0.2 µg/l to 1 µg/l - in December 2014 a load of 820 kg was estimated - Tetracarbonitrilpropen is stable Tetracarbonitrilpropen can be detected in samples from along the entire Rhine samples taken in 2013 at Maas-Luis showed nearly the same load It took 2 months from finding the unknown mass to identifying the compound. Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 12
13 Non-Target Screening: AMPS - initially, the concentration was estimated to be 150 ng/l using the internal standard Bentazon-D6 - the molecular structure was identified within one week!!! - the concentration was underestimated by 30-fold!!! Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 13
14 Non-Target Screening: AMPS - due to its polarity AMPS resides predominantly in the water phase - it cannot be completely removed by drinking water treatment detection of AMPS in drinking water It is necessary to pay special attention to polar substances! Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 14
15 15 LCMS-Rhine Alarms from AUE-BASEL in 2014 Substance Use Alarms 2014 Detection Load 2014 (kg) Paracetamol analgetic Feb 2014/ Nov 14 Semi-Quan 320 Aliskiren beta blocker Feb / March / April 14 Priority list 1400 Indometacin 2-Phenyl-2-(2- piperidin)acetamid analgetic beginning and end March 14 Semi-Quan 170 (in 2 weeks) Industrial chemical Feb - March 14 Nontarget 600 Toluol-4-sulfonic acid Industrial chemical Dez 14 Priority list 1500 Unknown_252 Sep 14 Nontarget 1300* Unknown_325 May 14 Nontarget 5000* Tizanidin Muscle relexant Jun 14 Priority list 150 Mecoprop Pesticide Jun 14 Priority list 320 Unknown_139 Jul 14 Nontarget 70* Tetracarbonitrilpropen Industrial chemical Nov 2014 (Info in Basel) Nontarget 14000* * load-estimation red marked substances = permanent pollutions Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 15
16 Rhine Monitoring in Basel 2010 FOCUS 2014 GCMS shifted LCMS Results Alarms 7 19 Load targets 15 t 90 t Load non-targets ca. 3 t (only GCMS) > 25 t Human resources + one full-time position Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 16
17 Summary new LC/MS technologies greatly enhance the analytical spectrum cooperation with scientific partners is necessary a daily target-analysis of nearly 300 relevant compounds is possible observed target-loads were multiplied by factor six daily non-target screening is important, using LC/MS and GC/MS techniques LC/MS non-target screening delivers relevant compounds with high loads personal statement: the benefit of the information gain greatly outweighs the cost of the additional human resources necessary Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 17
18 THANK YOU for your attention! Thanks also to: Anna Brunnert, Steffi Schreiber, Reto Dolf, Paul Svoboda and the entire AUE-Team Kanton Basel-Stadt Workshop IKSR, Steffen Ruppe, Folie 18
Unique Software Tools to Enable Quick Screening and Identification of Residues and Contaminants in Food Samples using Accurate Mass LC-MS/MS
Unique Software Tools to Enable Quick Screening and Identification of Residues and Contaminants in Food Samples using Accurate Mass LC-MS/MS Using PeakView Software with the XIC Manager to Get the Answers
AT&T Global Network Client for Windows Product Support Matrix January 29, 2015
AT&T Global Network Client for Windows Product Support Matrix January 29, 2015 Product Support Matrix Following is the Product Support Matrix for the AT&T Global Network Client. See the AT&T Global Network
Accurate Mass Screening Workflows for the Analysis of Novel Psychoactive Substances
Accurate Mass Screening Workflows for the Analysis of Novel Psychoactive Substances TripleTOF 5600 + LC/MS/MS System with MasterView Software Adrian M. Taylor AB Sciex Concord, Ontario (Canada) Overview
# LCMS-35 esquire series. Application of LC/APCI Ion Trap Tandem Mass Spectrometry for the Multiresidue Analysis of Pesticides in Water
Application Notes # LCMS-35 esquire series Application of LC/APCI Ion Trap Tandem Mass Spectrometry for the Multiresidue Analysis of Pesticides in Water An LC-APCI-MS/MS method using an ion trap system
Metabolomic Profiling of Accurate Mass LC-MS/MS Data to Identify Unexpected Environmental Pollutants
Metabolomic Profiling of Accurate Mass LC- Data to Identify Unexpected Environmental Pollutants André Schreiber 1, David Cox 1, Nadia Pace 1, Christopher Borton 2 1 AB SCIEX, Concord, ntario, Canada; 2
Pesticide residue analysis: New Trends. Michal Godula, Ph.D. EU Marketing Manager Food Safety & Environmental Thermo Fisher Scientific
Pesticide residue analysis: New Trends Michal Godula, Ph.D. EU Marketing Manager Food Safety & Environmental Thermo Fisher Scientific Why pesticide analysis? Extensively used in agriculture to control
COMPARISON OF FIXED & VARIABLE RATES (25 YEARS) CHARTERED BANK ADMINISTERED INTEREST RATES - PRIME BUSINESS*
COMPARISON OF FIXED & VARIABLE RATES (25 YEARS) 2 Fixed Rates Variable Rates FIXED RATES OF THE PAST 25 YEARS AVERAGE RESIDENTIAL MORTGAGE LENDING RATE - 5 YEAR* (Per cent) Year Jan Feb Mar Apr May Jun
COMPARISON OF FIXED & VARIABLE RATES (25 YEARS) CHARTERED BANK ADMINISTERED INTEREST RATES - PRIME BUSINESS*
COMPARISON OF FIXED & VARIABLE RATES (25 YEARS) 2 Fixed Rates Variable Rates FIXED RATES OF THE PAST 25 YEARS AVERAGE RESIDENTIAL MORTGAGE LENDING RATE - 5 YEAR* (Per cent) Year Jan Feb Mar Apr May Jun
Calculation of Molar Masses. Molar Mass. Solutions. Solutions
Molar Mass Molar mass = Mass in grams of one mole of any element, numerically equal to its atomic weight Molar mass of molecules can be determined from the chemical formula and molar masses of elements
How To Test For Contamination In Large Volume Water
Automated Solid Phase Extraction (SPE) of EPA Method 1694 for Pharmaceuticals and Personal Care Products in Large Volume Water Samples Keywords Application Note ENV0212 This collaboration study was performed
CARBON THROUGH THE SEASONS
DESCRIPTION In this lesson plan, students learn about the carbon cycle and understand how concentrations of carbon dioxide (CO 2 ) in the Earth s atmosphere vary as the seasons change. Students also learn
Element of same atomic number, but different atomic mass o Example: Hydrogen
Atomic mass: p + = protons; e - = electrons; n 0 = neutrons p + + n 0 = atomic mass o For carbon-12, 6p + + 6n 0 = atomic mass of 12.0 o For chlorine-35, 17p + + 18n 0 = atomic mass of 35.0 atomic mass
Unit 2: Quantities in Chemistry
Mass, Moles, & Molar Mass Relative quantities of isotopes in a natural occurring element (%) E.g. Carbon has 2 isotopes C-12 and C-13. Of Carbon s two isotopes, there is 98.9% C-12 and 11.1% C-13. Find
Determination of Pesticide Residues in Drinking Water Using Automated Solid-Phase Extraction and Gas Chromatography with Nitrogen Phosphorus Detection
Determination of Pesticide Residues in Drinking Water Using Automated Solid-Phase Extraction and Gas Chromatography with Nitrogen Phosphorus Detection Application Note 1097 Liu Qian, Zheng Hongguo and
STANDARD OPERATING PROCEDURES
PAGE: 1 of 33 CONTENTS 1.0 SCOPE AND APPLICATION 2.0 METHOD SUMMARY 3.0 SAMPLE PRESERVATION, CONTAINERS, HANDLING, AND STORAGE 4.0 INTERFERENCES AND POTENTIAL PROBLEMS 5.0 EQUIPMENT/APPARATUS 6.0 REAGENTS
Thermo Scientific ExactFinder Software
mass spectrometry Thermo Scientific ExactFinder Software Workflow software for routine targeted and general unknown screening Unifies qualitative and quantitative high-resolution accurate mass workflows
Case 2:08-cv-02463-ABC-E Document 1-4 Filed 04/15/2008 Page 1 of 138. Exhibit 8
Case 2:08-cv-02463-ABC-E Document 1-4 Filed 04/15/2008 Page 1 of 138 Exhibit 8 Case 2:08-cv-02463-ABC-E Document 1-4 Filed 04/15/2008 Page 2 of 138 Domain Name: CELLULARVERISON.COM Updated Date: 12-dec-2007
Analysis of Free Bromate Ions in Tap Water using an ACQUITY UPLC BEH Amide Column
Analysis of Free Bromate Ions in Tap Water using an ACQUITY UPLC BEH Amide Column Sachiki Shimizu, FUJIFILM Fine Chemicals Co., Ltd., Kanagawa, Japan Kenneth J. Fountain, Kevin Jenkins, and Yoko Tsuda,
Mass Spectrometry. Overview
Mass Spectrometry Overview Mass Spectrometry is an analytic technique that utilizes the degree of deflection of charged particles by a magnetic field to find the relative masses of molecular ions and fragments.2
CALL VOLUME FORECASTING FOR SERVICE DESKS
CALL VOLUME FORECASTING FOR SERVICE DESKS Krishna Murthy Dasari Satyam Computer Services Ltd. This paper discusses the practical role of forecasting for Service Desk call volumes. Although there are many
Daniel M. Mueller, Katharina M. Rentsch Institut für Klinische Chemie, Universitätsspital Zürich, CH-8091 Zürich, Schweiz
Toxichem Krimtech 211;78(Special Issue):324 Online extraction LC-MS n method for the detection of drugs in urine, serum and heparinized plasma Daniel M. Mueller, Katharina M. Rentsch Institut für Klinische
2014 Aamjiwnaang Air Monitoring Station Results. Ministry of the Environment and Climate Change April 19, 2016
2014 Aamjiwnaang Air Monitoring Station Results Ministry of the Environment and Climate Change April 19, 2016 Outline Key Results Parameters Measured Benchmarks 2014 Report Results Mobile Monitoring Results
Metabolomics Software Tools. Xiuxia Du, Paul Benton, Stephen Barnes
Metabolomics Software Tools Xiuxia Du, Paul Benton, Stephen Barnes Outline 2 Introduction Software Tools for LC-MS metabolomics Software Tools for GC-MS metabolomics Software Tools for Statistical Analysis
Coordination and air quality monitoring during emergencies. Colin Powlesland Environment Agency
Coordination and air quality monitoring during emergencies Colin Powlesland Environment Agency Contents h Introduction h What do we want to achieve? h Implementation programme h Incident timeline h Proposed
List the 3 main types of subatomic particles and indicate the mass and electrical charge of each.
Basic Chemistry Why do we study chemistry in a biology course? All living organisms are composed of chemicals. To understand life, we must understand the structure, function, and properties of the chemicals
Enhanced Vessel Traffic Management System Booking Slots Available and Vessels Booked per Day From 12-JAN-2016 To 30-JUN-2017
From -JAN- To -JUN- -JAN- VIRP Page Period Period Period -JAN- 8 -JAN- 8 9 -JAN- 8 8 -JAN- -JAN- -JAN- 8-JAN- 9-JAN- -JAN- -JAN- -JAN- -JAN- -JAN- -JAN- -JAN- -JAN- 8-JAN- 9-JAN- -JAN- -JAN- -FEB- : days
Finokalia Station - University of Crete (Greece) ECPL
Finokalia Station - University of Crete (Greece) ECPL Institution information The Environmental Chemical Processes Laboratory (ECPL) was established in 1997 by the Department of Chemistry and the Senate
Climatography of the United States No. 20 1971-2000
Climate Division: CA 4 NWS Call Sign: Month (1) Min (2) Month(1) Extremes Lowest (2) Temperature ( F) Lowest Month(1) Degree s (1) Base Temp 65 Heating Cooling 1 Number of s (3) Jan 59.3 41.7 5.5 79 1962
Biocides main groups
Analytical challenges for the analysis of biocides in aqueous and solid environmental matrices Arne Wick, Kathrin Broeder, Michael Schluesener, Thomas Ternes Federal Institute of Hydrology (BfG), Koblenz,
The Mole Concept. The Mole. Masses of molecules
The Mole Concept Ron Robertson r2 c:\files\courses\1110-20\2010 final slides for web\mole concept.docx The Mole The mole is a unit of measurement equal to 6.022 x 10 23 things (to 4 sf) just like there
Deployment of networks of innovative water quality sensors for distribution network monitoring Joep van den Broeke (Ph.D.)
AWWA Water Infrastructure Conference Deployment of networks of innovative water quality sensors for distribution network monitoring Joep van den Broeke (Ph.D.) 28 October 2014 Challenges for Water Utilities
Climatography of the United States No. 20 1971-2000
Climate Division: CA 6 NWS Call Sign: SAN Month (1) Min (2) Month(1) Extremes Lowest (2) Temperature ( F) Lowest Month(1) Degree s (1) Base Temp 65 Heating Cooling 100 Number of s (3) Jan 65.8 49.7 57.8
Unity Lab Services Training Courses
Unity Lab Services Training Courses the key to your laboratory s success 2015 North America Training Course Calendar LC-MS COURSE JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV DEC LTQ Family Operations 26-29
Chemical Proportions in Compounds
Chapter 6 Chemical Proportions in Compounds Solutions for Practice Problems Student Textbook page 201 1. Problem A sample of a compound is analyzed and found to contain 0.90 g of calcium and 1.60 g of
Chemical Composition Review Mole Calculations Percent Composition. Copyright Cengage Learning. All rights reserved. 8 1
Chemical Composition Review Mole Calculations Percent Composition Copyright Cengage Learning. All rights reserved. 8 1 QUESTION Suppose you work in a hardware store and a customer wants to purchase 500
The Empirical Formula of a Compound
The Empirical Formula of a Compound Lab #5 Introduction A look at the mass relationships in chemistry reveals little order or sense. The ratio of the masses of the elements in a compound, while constant,
Strategies for analysis of unknown samples Non targeted screening with LC TOF Examples from the Swedish National Food Agency
Strategies for analysis of unknown samples Non targeted screening with LC TOF Examples from the Swedish National Food Agency Johan Rosén Chemist Science department, Chemistry Division National Food Agency,
AMD Analysis & Technology AG
AMD Analysis & Technology AG Application Note 120419 Author: Karl-Heinz Maurer APCI-MS Trace Analysis of volatile organic compounds in ambient air A) Introduction Trace analysis of volatile organic compounds
Analysis One Code Desc. Transaction Amount. Fiscal Period
Analysis One Code Desc Transaction Amount Fiscal Period 57.63 Oct-12 12.13 Oct-12-38.90 Oct-12-773.00 Oct-12-800.00 Oct-12-187.00 Oct-12-82.00 Oct-12-82.00 Oct-12-110.00 Oct-12-1115.25 Oct-12-71.00 Oct-12-41.00
State Water Resources Control Board Environmental Laboratory Accreditation Program
State Water Resources Control Board Environmental Laboratory Accreditation Program P.O. Box 100, Floor 24 850 Marina Bay Parkway, Build. P 500 N Central Ave, Suite 500 Sacramento, CA 95812-0100 Richmond,
Chemical Calculations: The Mole Concept and Chemical Formulas. AW Atomic weight (mass of the atom of an element) was determined by relative weights.
1 Introduction to Chemistry Atomic Weights (Definitions) Chemical Calculations: The Mole Concept and Chemical Formulas AW Atomic weight (mass of the atom of an element) was determined by relative weights.
MassHunter for Agilent GC/MS & GC/MS/MS
MassHunter for Agilent GC/MS & GC/MS/MS Next Generation Data Analysis Software Presented by : Terry Harper GC/MS Product Specialist 1 Outline of Topics Topic 1: Introduction to MassHunter Topic 2: Data
Performance and advantages of qnmr measurements
Return to Web Version This is the first of a series of articles related to the launch of new organic CRMs certified by quantitative NMR under double accreditation. In this issue, we focus on CRMs intended
Micropollutants in the aquatic environment: The Swiss strategy
Micropollutants in the aquatic environment: The Swiss strategy Adriano Joss, Hansruedi Siegrist (eawag), Michael Schärer, Christian Abegglen (Bafu, VSA) Hilversum, 21 November 2013 Overview The Swiss strategy
Formulas, Equations and Moles
Chapter 3 Formulas, Equations and Moles Interpreting Chemical Equations You can interpret a balanced chemical equation in many ways. On a microscopic level, two molecules of H 2 react with one molecule
UHPLC/MS: An Efficient Tool for Determination of Illicit Drugs
Application Note: 439 UHPLC/MS: An Efficient Tool for Determination of Illicit Drugs Guifeng Jiang, Thermo Fisher Scientific, San Jose, CA, USA Key Words Accela UHPLC System MSQ Plus MS Detector Drugs
Agilent LCMS products and the application strategies in veterinary drug analysis
Agilent LCMS products and the application strategies in veterinary drug analysis Experience A New Level of Confidence Ma Xin 马 鑫 LCMS Application Engineer Internal Sales Training - The new 6495 QQQ LC/MS
Pesticide Analysis by Mass Spectrometry
Pesticide Analysis by Mass Spectrometry Purpose: The purpose of this assignment is to introduce concepts of mass spectrometry (MS) as they pertain to the qualitative and quantitative analysis of organochlorine
2015-16 BCOE Payroll Calendar. Monday Tuesday Wednesday Thursday Friday Jun 29 30 Jul 1 2 3. Full Force Calc
July 2015 CM Period 1501075 July 2015 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 August 2015 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Thermo Scientific GC-MS Data Acquisition Instructions for Cerno Bioscience MassWorks Software
Thermo Scientific GC-MS Data Acquisition Instructions for Cerno Bioscience MassWorks Software Mark Belmont and Alexander N. Semyonov, Thermo Fisher Scientific, Austin, TX, USA Ming Gu, Cerno Bioscience,
PosterREPRINT AN LC/MS ORTHOGONAL TOF (TIME OF FLIGHT) MASS SPECTROMETER WITH INCREASED TRANSMISSION, RESOLUTION, AND DYNAMIC RANGE OVERVIEW
OVERVIEW Exact mass LC/MS analysis using an orthogonal acceleration time of flight (oa-tof) mass spectrometer is a well-established technique with a broad range of applications. These include elemental
2013-2014. oct 03 / 2013 nov 12 / 2013. oct 05 / 2013. oct 07 / 2013. oct 21 / 2013. oct 24 / 2013. nov 07 / 2013 nov 14 / 2013.
2013- ACADEMIC CALENDARS SOUTH UNIVERSITY 2013- ACADEMIC CALENDAR Fall 2013 Winter Spring Summer New Student Orientation Session II (Mid ) oct 03 / 2013 nov 12 / 2013 jan 09 / feb 18 / apr 03 / may 13
AS1 MOLES. oxygen molecules have the formula O 2 the relative mass will be 2 x 16 = 32 so the molar mass will be 32g mol -1
Moles 1 MOLES The mole the standard unit of amount of a substance the number of particles in a mole is known as Avogadro s constant (L) Avogadro s constant has a value of 6.023 x 10 23 mol -1. Example
S olid Ph ase Extraction (SP E) Method:
Solid Phase Extraction of US EPA 535 for Chloroacetanilide and Acetamide Degradates in Drinking Water Samples Prior to Liquid Chromatography/ Tandem Mass Spectrometry Toni Hofhine, Horizon Technology,
Atomic Masses. Chapter 3. Stoichiometry. Chemical Stoichiometry. Mass and Moles of a Substance. Average Atomic Mass
Atomic Masses Chapter 3 Stoichiometry 1 atomic mass unit (amu) = 1/12 of the mass of a 12 C atom so one 12 C atom has a mass of 12 amu (exact number). From mass spectrometry: 13 C/ 12 C = 1.0836129 amu
F321 THE STRUCTURE OF ATOMS. ATOMS Atoms consist of a number of fundamental particles, the most important are... in the nucleus of an atom
Atomic Structure F32 TE STRUCTURE OF ATOMS ATOMS Atoms consist of a number of fundamental particles, the most important are... Mass / kg Charge / C Relative mass Relative Charge PROTON NEUTRON ELECTRON
Environmental Water Testing: Surface Water, Groundwater, Hard Water, Wastewater, & Seawater
Document: AND Sol Env 08 2013 Environmental Water Testing: Surface Water, Groundwater, Hard Water, Wastewater, & Seawater Matrix specific sample preparation and testing methods for environmental waters
Computing & Telecommunications Services Monthly Report March 2015
March 215 Monthly Report Computing & Telecommunications Services Monthly Report March 215 CaTS Help Desk (937) 775-4827 1-888-775-4827 25 Library Annex helpdesk@wright.edu www.wright.edu/cats/ Last Modified
Part One: Mass and Moles of Substance. Molecular Mass = sum of the Atomic Masses in a molecule
CHAPTER THREE: CALCULATIONS WITH CHEMICAL FORMULAS AND EQUATIONS Part One: Mass and Moles of Substance A. Molecular Mass and Formula Mass. (Section 3.1) 1. Just as we can talk about mass of one atom of
Using Natural Products Application Solution with UNIFI for the Identification of Chemical Ingredients of Green Tea Extract
Using Natural Products Application Solution with UNIFI for the Identification of Chemical Ingredients of Green Tea Extract Lirui Qiao, 1 Rob Lewis, 2 Alex Hooper, 2 James Morphet, 2 Xiaojie Tan, 1 Kate
F321 MOLES. Example If 1 atom has a mass of 1.241 x 10-23 g 1 mole of atoms will have a mass of 1.241 x 10-23 g x 6.02 x 10 23 = 7.
Moles 1 MOLES The mole the standard unit of amount of a substance (mol) the number of particles in a mole is known as Avogadro s constant (N A ) Avogadro s constant has a value of 6.02 x 10 23 mol -1.
For example: (Example is from page 50 of the Thinkbook)
SOLVING COMBINED SPECTROSCOPY PROBLEMS: Lecture Supplement: page 50-53 in Thinkbook CFQ s and PP s: page 216 241 in Thinkbook Introduction: The structure of an unknown molecule can be determined using
TargetQuan 3 Software. Leading the way in regulatory. POPs quantification. Bullet Bullet Bullet
TargetQuan 3 Software Leading the way in regulatory POPs quantification Bullet Bullet Bullet Leading the way in regulatory POPs quantification Analyse Samples Open Sequence Process Sequence Analyse Samples
Organic Chemistry Calculations
Organic Chemistry Calculations There are three basic units for measurement in the organic laboratory mass, volume, and number, measured in moles. Most of the other types of measurements are combinations
Chemistry 65 Chapter 6 THE MOLE CONCEPT
THE MOLE CONCEPT Chemists find it more convenient to use mass relationships in the laboratory, while chemical reactions depend on the number of atoms present. In order to relate the mass and number of
Performing Calculatons
Performing Calculatons There are three basic units for measurement in the organic laboratory mass, volume, and number, measured in moles. Most of the other types of measurements are combinations of them,
Technical Report. Automatic Identification and Semi-quantitative Analysis of Psychotropic Drugs in Serum Using GC/MS Forensic Toxicological Database
C146-E175A Technical Report Automatic Identification and Semi-quantitative Analysis of Psychotropic Drugs in Serum Using GC/MS Forensic Toxicological Database Hitoshi Tsuchihashi 1 Abstract: A sample consisting
Problem Solving. Empirical Formulas
Skills Worksheet Problem Solving Empirical Formulas Suppose you analyze an unknown compound that is a white powder and find that it is composed of 36.5% sodium, 38.1% oxygen, and 25.4% sulfur. You can
B i o s o l u t i o n s
B i o s o l u t i o n s Implementation of pharmatracker TM : A case study Prepared by Ocimum Biosolutions Ocimumbio Solutions August 2006 All rights reserved. 2 B i o s o l u t i o n s an ISO 9001:2000
Reisevertrieb unter der Lupe: Was buchen die Deutschen wirklich? 1. Travel Sales with a fine-toothed comb: What are Germans actually booking?
GfK Gruppe Reisevertrieb unter der Lupe: Was buchen die Deutschen wirklich? 1 Travel Sales with a fine-toothed comb: What are Germans actually booking? ITB Marketing & Sales Day Hery-Charles Eckert GfK
NITRIC OXIDE and NITROGEN DIOXIDE 6014
NITRIC OXIDE and NITROGEN DIOXIDE 6014 NO MW: 30.01 CAS: 10102-43-9 RTECS: QX0525000 46.01 10102-44-0 QW9800000 METHOD: 6014, Issue 1 EVALUATION: FULL Issue 1: 15 August 1994 OSHA : 25 ppm NO; C 1 ppm
Analysis of the Vitamin B Complex in Infant Formula Samples by LC-MS/MS
Analysis of the Vitamin B Complex in Infant Formula Samples by LC-MS/MS Stephen Lock 1 and Matthew Noestheden 2 1 AB SCIEX Warrington, Cheshire (UK), 2 AB SCIEX Concord, Ontario (Canada) Overview A rapid,
7-5.5. Translate chemical symbols and the chemical formulas of common substances to show the component parts of the substances including:
7-5.5 Translate chemical symbols and the chemical formulas of common substances to show the component parts of the substances including: NaCl [salt], H 2 O [water], C 6 H 12 O 6 [simple sugar], O 2 [oxygen
Getting the most from this book...4 About this book...5
Contents Getting the most from this book...4 About this book....5 Content Guidance Topic 1 Atomic structure and the periodic table...8 Topic 2 Bonding and structure...14 Topic 2A Bonding....14 Topic 2B
Simple vs. True. Simple vs. True. Calculating Empirical and Molecular Formulas
Calculating Empirical and Molecular Formulas Formula writing is a key component for success in chemistry. How do scientists really know what the true formula for a compound might be? In this lesson we
The Mole and Molar Mass
The Mole and Molar Mass 1 Molar mass is the mass of one mole of a substance. Molar mass is numerically equal to atomic mass, molecular mass, or formula mass. However the units of molar mass are g/mol.
Job posting. other. Fourteen Research Positions in bio-diagnosis and chemical structure elucidation (13 PhD students and 1 postdoc)
Job posting Type of position scientific administrative Target group graduates post docs other Title Institution Fourteen Research Positions in bio-diagnosis and chemical structure elucidation (13 PhD students
Proficiency Testing In A Global Analytical Environment Benefits & Challenges. AOAC September 2007
Proficiency Testing In A Global Analytical Environment Benefits & Challenges AOAC September 2007 1 The Coca-Cola Company The Coca-Cola Company is the largest manufacturer, distributor and marketer of nonalcoholic
Interest Rates. Countrywide Building Society. Savings Growth Data Sheet. Gross (% per annum)
Interest Rates (% per annum) Countrywide Building Society This is the rate of simple interest earned in a year (before deducting tax). Dividing by 12 gives the monthly rate of interest. Annual Equivalent
Overview. Introduction. AB SCIEX MPX -2 High Throughput TripleTOF 4600 LC/MS/MS System
Investigating the use of the AB SCIEX TripleTOF 4600 LC/MS/MS System for High Throughput Screening of Synthetic Cannabinoids/Metabolites in Human Urine AB SCIEX MPX -2 High Throughput TripleTOF 4600 LC/MS/MS
HP ArcSight User Behavior Analytics
Insider Threat HP ArcSight User Behavior Analytics Application Misuse Sensitive Data Access Hakan Durgut ArcSight Specialist Nordics/Baltics 1 The insider threat challenge IT Security focus in on the external
Increasing Quality While Maintaining Efficiency in Drug Chemistry with DART-TOF MS Screening
Increasing Quality While Maintaining Efficiency in Drug Chemistry with DART-TOF MS Screening Application Note Forensics Author Erin Shonsey Director of Research Alabama Department of Forensic Science Abstract
How To Calculate Mass In Chemical Reactions
We have used the mole concept to calculate mass relationships in chemical formulas Molar mass of ethanol (C 2 H 5 OH)? Molar mass = 2 x 12.011 + 6 x 1.008 + 1 x15.999 = 46.069 g/mol Mass percentage of
A new concept for isotope ratio monitoring LC/MS. A Wide Range of Applications
A new concept for isotope ratio monitoring LC/MS A Wide Range of Applications Andreas Hilkert, Dieter Juchelka, Michael Krummen Thermo Electron (Bremen) GmbH Overview Introduction in Isotope Ratio Monitoring-LC/MS
Chemistry 321, Experiment 8: Quantitation of caffeine from a beverage using gas chromatography
Chemistry 321, Experiment 8: Quantitation of caffeine from a beverage using gas chromatography INTRODUCTION The analysis of soft drinks for caffeine was able to be performed using UV-Vis. The complex sample
EPA Radionuclides Rule and the RadNet Program
EPA Radionuclides Rule and the RadNet Program Kelly Moran (215) 814-2331 moran.kelly@epa.gov 7/20/2011 U.S. Environmental Protection Agency 1 What is a radionuclide (radioisotope)? element - any one of
Beware that Low Urine Creatinine! by Vera F. Dolan MSPH FALU, Michael Fulks MD, Robert L. Stout PhD
1 Beware that Low Urine Creatinine! by Vera F. Dolan MSPH FALU, Michael Fulks MD, Robert L. Stout PhD Executive Summary: The presence of low urine creatinine at insurance testing is associated with increased
Overview. Triple quadrupole (MS/MS) systems provide in comparison to single quadrupole (MS) systems: Introduction
Advantages of Using Triple Quadrupole over Single Quadrupole Mass Spectrometry to Quantify and Identify the Presence of Pesticides in Water and Soil Samples André Schreiber AB SCIEX Concord, Ontario (Canada)
Prozessautomatisierung mit SAP Netweaver BPM bei Boehringer Ingelheim 20. Mai 2014
Prozessautomatisierung mit SAP Netweaver BPM bei Boehringer Ingelheim 20. Mai 2014 Dr. Torsten Grünewald Global Business Services / Process Management Boehringer Ingelheim Pharma GmbH&Co KG Boehringer
Prentice Hall. Chemistry (Wilbraham) 2008, National Student Edition - South Carolina Teacher s Edition. High School. High School
Prentice Hall Chemistry (Wilbraham) 2008, National Student Edition - South Carolina Teacher s Edition High School C O R R E L A T E D T O High School C-1.1 Apply established rules for significant digits,
CHAPTER 8: CHEMICAL COMPOSITION
CHAPTER 8: CHEMICAL COMPOSITION Active Learning: 1-4, 6-8, 12, 18-25; End-of-Chapter Problems: 3-4, 9-82, 84-85, 87-92, 94-104, 107-109, 111, 113, 119, 125-126 8.2 ATOMIC MASSES: COUNTING ATOMS BY WEIGHING
How much does a single atom weigh? Different elements weigh different amounts related to what makes them unique.
How much does a single atom weigh? Different elements weigh different amounts related to what makes them unique. What units do we use to define the weight of an atom? amu units of atomic weight. (atomic
Chemical Profiling and Differential Analysis of Whiskies Using Orbitrap GC-MS
Chemical Profiling and Differential Analysis of Whiskies Using Orbitrap GC-MS Dominic Roberts, 1 Jana Hajslova, 2 Jana Pulkrabova, 2 and Paul Silcock 1 1 Thermo Fisher Scientific, Runcorn, UK 2 University
Chapter 3: Stoichiometry
Chapter 3: Stoichiometry Key Skills: Balance chemical equations Predict the products of simple combination, decomposition, and combustion reactions. Calculate formula weights Convert grams to moles and
P/T 2B: 2 nd Half of Term (8 weeks) Start: 26-AUG-2013 End: 20-OCT-2013 Start: 21-OCT-2013 End: 15-DEC-2013
2013-2014 SPECIAL TERM ACADEMIC CALENDAR FOR SCRANTON EDUCATION ONLINE (SEOL), MBA ONLINE, HUMAN RESOURCES ONLINE, NURSE ANESTHESIA and ERP PROGRAMS SPECIAL FALL 2013 TERM Key: P/T = Part of Term P/T Description
P/T 2B: 2 nd Half of Term (8 weeks) Start: 25-AUG-2014 End: 19-OCT-2014 Start: 20-OCT-2014 End: 14-DEC-2014
2014-2015 SPECIAL TERM ACADEMIC CALENDAR FOR SCRANTON EDUCATION ONLINE (SEOL), MBA ONLINE, HUMAN RESOURCES ONLINE, NURSE ANESTHESIA and ERP PROGRAMS SPECIAL FALL 2014 TERM Key: P/T = Part of Term P/T Description
Climatography of the United States No. 20 1971-2000
Climate Division: CA 2 NWS Call Sign: SAC Month (1) Min (2) Month(1) Extremes Lowest (2) Temperature ( F) Lowest Month(1) Degree s (1) Base Temp 65 Heating Cooling 100 Number of s (3) Jan 53.8 38.8 46.3
Micromass LCT User s Guide
Micromass LCT User s Guide 1) Log on to MassLynx with your username & password. 2) After you have logged in, the MassLynx software will automatically run. 3) After MassLynx has come up, open your project