Modena International Breast Cancer Conference



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Modena International Breast Cancer Conference 6 th meet the professor Modena, 15-17 September 2010 Section of Oncology

http://meettheprofessor.accmed.org

Aims The breast cancer meeting in Modena started six years ago as a Meet the Professor initiative to facilitate the discussion among recognized Experts and physicians involved in breast cancer management. Over the years, the number and the expertise of the attendees has increased as has the scientific content of the meeting. This sixth edition, as can be judged from the title itself, represents the definitive transition to an international conference aimed to gather some of the top scientists and clinicians from all over the word. This 6 th Modena International Breast Cancer Conference will emphasize the progress made in the prevention and management of breast cancer, will allow a fruitful and multidisciplinary discussion of controversial issues and clinical cases and will give insights on the most exciting advances in breast cancer biology and therapy. In order to reward scientific excellence and facilitate international cooperation, the International Scientific Committee of MIBCC 6 th, will award the First International UniMore Prize for Breast Cancer Research to a young scientist who has published a breakthrough paper in the previous year and the Monica Boscolo Research Grant to an Italian scientist willing to pursue a research project in a foreign institution. Medical oncologists, breast surgeons, radiologists, pathologists and basic scientists interested in translational research are welcome to Modena to listen to breast cancer leaders and exchange experience in a friendly atmosphere. Addressed to pier Franco Conte, Gabriel N. Hortobagyi Oncologists, radiologists, breast surgeons ECM Application for ECM credits for Italian participants will be requested to the Italian Ministry of Health. The number of credits will be advised on the Accademia Nazionale di Medicina s web site: www.accmed.org. The credit certification is subject to the accreditation by the Ministry of Health, the full attendance of the meeting, the completion of the meeting evaluation test and the event evaluation form, the correspondance between the participant s profession and the professional categories defined as physicians (specialized in oncology, radiology, breast surgery). ESMO-MORA CREDITS The course has been accredited with 16 Esmo-Mora Points category 1.

Official Language The official language of the Meeting is English. No simoultaneous translation will be provided. Registration The registration fee is 250,00 tax free. It includes the conference bag, the conference book and all coffee breaks and lunches. It does not include hotel accommodation, dinners and travel expenses. To register, please send: registration form duly filled out privacy statement and consent to the use of personal data (as in the back of the form) payment to Accademia Nazionale di Medicina Palazzina CUP II Piano, Via Massarenti 9, 40138 Bologna, fax 0039 051 6364605 e.mail: info.bologna@accmed.org, within July 20 th. Online registration is possible on the website http://meettheprofessor.accmed.org By submitting the form and the payment, your registration is completed with the exception of specific decisions of the Meeting Secretariat. Incomplete registration will NOT be admitted. CANCELLATION If the participants minimum number is not reached, Accademia Nazionale di Medicina will give notice with a written communication and proceed with the total refund of the fee. In order to cancel please give notice with a written communication to Accademia Nazionale di Medicina within September 1 st. A 70% of the registration fee will be returned. Any cancellation after that deadline will not be reimbursed. Social Programme On September 16 th a social dinner will take place at the Military Academy in Modena (Piazza Roma, 15). In order to participate it is necessary to make a reservation within September 1 st paying the quote for the dinner ( 60,00) together with the subscription quote for the course.

Programme Wednesday, September 15 9.30 Lecture 1 Biology of BRCA associated breast cancer Generoso Bevilacqua 10.00 Lecture 2 Hereditary breast cancer not related to BRCA 1/2 Maria Adelaide Caligo 10.30 Discussion and coffee 11.00 Round Table Management of BRCA healthy carriers Chair: Massimo Federico Surveillance - Pierosandro Tagliaferri Surgery - Manuela Roncella Chemoprevention - Andrea De Censi 12.00 Lecture 3 The familial breast cancer clinic Massimo Federico 12.30 From technology advances to patient care 1 Lecture 4 Gene profiling: role in clinical trial design and patient management Lajos Pusztai 13.15 Lunch 14.15 From technology advances to patient care 2 Chair: Pietro Torricelli Controversy 1- MRI the good Christiane Kuhl MRI the bad Monica Morrow 15.15 Lecture 5 PET- Scan for staging and monitoring Norbert Avril 15.45 Discussion and coffee 16.15 Lecture 6 Primary systemic therapy for operable breast cancer: from drug development to clinical practice Luca Gianni 16.45 Clinical case discussions - 1 Genetic counselling and screening Laura Cortesi Management of ADH and DCIS Maria Grazia Lazzaretti Molecular subtypes and gene expression profiles Lucia Del Mastro 17.15 Reports of Clinical cases and open discussion Gianni Tazzioli, Antonio Maiorana 18.00 Adjourn

Thursday, September 16 8.30 Lecture 7 How many breast cancers subtypes for clinicians? Giuseppe Viale 9.00 Controversy 2- Accelerated partial breast irradiation: is it ready as a standard treatment approach? Yes/ No Roberto Orecchia, Silvia Formenti 10.00 Lecture 8 Does breast cancer subtype influence locoregional treatments? Eleuterios Mamounas 10.30 Discussion and coffee 11.00 Lecture 9 Adjuvant treatment of EBC 2010 Gabriel N. Hortobagyi 11.45 Lecture 10 Adjuvant chemotherapy for node negative patients: translating scientific evidence into daily practice Miguel Martin 12.15 Lecture 11 HER2+ EBC: unanswered questions Pier Franco Conte 12.45 Lecture 12 TN disease: from biology to treatment Ana Maria Gonzalez-Angulo 13.15 Lunch 14.15 Clinical case discussions - 2 Sentinel node biopsy and primary systemic therapy Eleuterios Mamounas Adjuvant treatment of T1N0 Her2+ tumors Fabio Puglisi HR+ EBC: criteria to prescribe chemotherapy Anna Maria Molino 15.00 Reports of Clinical cases and open discussion Alberto Bottini, Paolo Pronzato 15.30 Coffee break 16.00 Lecture 13 Inflammatory breast cancer Hussein Khaled 16.30 Lecture 14 Breast cancer stem cells Maria Grazia Daidone 17.00 Ceremony for the presentation of the UniMore Award and the Monica Boscolo Research Grant 17.15 Lecture of the UniMore awardee 17.45 Adjourn

Friday, September 17 8.30 Lecture 15 HR+ disease: from cross-talk to overcome endocrine resistance Stephen Johnston 9.00 Lecture 16 Breast cancer and the bone Antonio Frassoldati 9.20 Lecture 17 Parp inhibition: from synthetic lethality to a new standard for triple negative tumors Stephen Johnston 9.40 Lecture 18 HER2+ breast cancer: new options, new challenges Valentina Guarneri 10.00 Coffee break 10.30 Clinical case discussions - 3 Multidisciplinary management of CNS metastases Claudio Zamagni Multidisciplinary management of oligometastastic disease Carmelo Bengala Multidisciplinary management of bone metastases Roberto Sabbatini 11.10 Reports of Clinical cases and open discussion Ana Maria Gonzalez-Angulo, Christoph Zielienski 11.40 Expert Panel Discussion: Inhibition of angiogenesis: who and when Chair: David Khayat Participants: Pier Franco Conte, Gabriel N. Hortobagyi, Fikri Içli, Hussein Khaled, Sibylle Loibl, Miguel Martin, Stephen Johnston, Christoph Zielienski 12.30 Lecture 19 Emerging therapeutic targets in breast cancer Suzette Delaloge 13.00 Adjourn and final evaluation questionnaire

Directors Pier Franco Conte Gabriel N. Hortobagyi Department of Breast Medical Oncology University of Texas - MD Anderson Cancer Center Houston (USA)

Scientific Committee Fikri Içli Oncology Research and Treatment Center Ankara University (T) Jacek Jassem Department of Oncology and Radiotherapy Medical University of Gdansk (P) Stephen Johnston NIHR Biomedical Research Centre for Cancer Royal Marsden NHS Foundation Trust & Institute of Cancer Research London (UK) Scientific Secretariat Antonio Frassoldati Valentina Guarneri Hussein Khaled Medical Oncology Department - National Cancer Institute Cairo University (Et) David Khayat French Cancer National Institute Paris (F) Sibylle Loibl German Breast Cancer Neu-Isenburg (D) Miguel Martin Medical Oncology Service Hospital Universitario Gregorio Maranon Madrid (E) Christoph Zielinski Clinical Division of Oncology - Medical University - General Hospital Vienna (A)

Speakers Norbert Avril Department of Nuclear Medicine Barts and The London School of Medicine University of London (UK) Carmelo Bengala Generoso Bevilacqua Division of Surgical, Molecular and Ultrastructural Pathology University of Pisa (I) Alberto Bottini Breast Unit Cremona Hospital (I) Maria Adelaide Caligo Section of Oncological Genetics Santa Chiara Hospital Pisa (I) Laura Cortesi Maria Grazia Daidone Department of Experimental Oncology and Molecular Medicine National Cancer Institut Milan (I) Andrea De Censi Division of Medical Oncology EO Ospedali Galliera Genoa (I) Suzette Delaloge Breast Medical Oncology Unit Gustave Roussy Institute of Cancer Villeneuf Cedex (F) Lucia Del Mastro Department of Medical Oncology National Cancer Research Institute Genoa (I)

Massimo Federico Medical Oncology II, Silvia Formenti Departments of Radiation Oncology And Medicine Clinical Cancer Center New York (USA) Antonio Frassoldati Luca Gianni Medical Oncology 1 National Cancer Institut Milan (I) Ana Maria Gonzalez-Angulo Breast Medical Oncology MD Anderson Cancer Center Houston, Texas (USA) Valentina Guarneri Fikri Içli Oncology Research And Treatment Center Ankara University (T) Stephen Johnston NIHR Biomedical Research Centre for Cancer Royal Marsden NHS Foundation Trust & Institute of Cancer Research London (UK) Hussein Khaled Medical Oncology Department - National Cancer Institute Cairo University (ET) David Khayat French Cancer National Institute Paris (F) Christiane Kuhl Department of Radiology University of Bonn (D)

Maria Grazia Lazzaretti Breast Unit Ramazzini Hospital Carpi, Modena (I) Sibylle Loibl German Breast Cancer Neu- Isenburg (D) Antonio Maiorana Anna Maria Molino Breast Unit University Hospital Verona (I) Eleuterios Mamounas Brest Cancer Unit Altman Health Foundation Canton Ohio (USA) Miguel Martin Medical Oncology Service Hospital Universitario Gregorio Maranon Madrid (E) Monica Morrow Breast Service, Department of Surgery Memorial Sloan-Kettering Cancer Center New York (USA) Roberto Orecchia Department of Radiotherapy European Institute of Oncology Milan (I) Paolo Pronzato Department of Medical Oncology National Cancer Research Institute Genoa (I) Fabio Puglisi Department of Oncology University Hospital of Udine (I)

Lajos Puzstai Department Of Breast Medical Oncology The University Of Texas M. D. Anderson Cancer Center Houston, Texas (USA) Manuela Roncella Breast Unit University Hospital S. Chiara Pisa (I) Roberto Sabbatini Pierosandro Tagliaferri Mater Domini University Hospital Magna Græcia University Catanzaro (I) Pietro Torricelli Department of Radiology Giuseppe Viale Department of Pathology European Institute of Oncology University of Milan (I) Claudio Zamagni Medical Oncology Unit Policlinico S.Orsola-Malpighi Hospital Bologna (I) Christoph Zielinski Clinical Division of Oncology Medical University - General Hospital Vienna (A) Giovanni Tazzioli Department of General Surgery and Surgical Specialties

with the patronage of: University of Modena and Reggio Emilia Associazione Italiana di Oncologia Medica Associazione Italiana di Radioterapia Oncologica

Special thanks to (request for authorization to the Ministry of Health) Gold sponsor Silver sponsor bronze sponsor Contributors Abraxis Bioscience Bayer Schering Pharma Pierre Fabre Pharma

Meeting VENUE Aula Magna Centro Didattico A.O.U. Policlinico di Modena Via del Pozzo, 71 Modena How to reach the meeting venue: By car arriving from the North: exit Modena North, follow the signs to City Center-Bologna Strada Statale, then follow directions to the Hospital Policlinico of Modena. By car arriving from the South: exit Modena South, turn right then keep going for 10 Km, at the mandatory turn sign, turn right and follow the street to the end. By train: Modena train station, bus n. 7 By plane: Bologna Airport 40 Km Sponsored by ACCADEMIA NAZIONALE DI MEDICINA www.accmed.org General Manager: Stefania Ledda In a joint collaboration with: Integrated Department of Oncology and Haematology, University of Modena and Reggio Emilia ORGANIZING PARTNER Forum Service Via Martin Piaggio 17/6 16122 Genova Information: http://meettheprofessor.accmed.org Ph. 0039 051 6364898-6360080 Fax 0039 051 6364605 info.bologna@accmed.org Hotel booking: Ph. 0039 010 83794243 Fax 0039 010 83794261 booking@forumservice.net Scholarship Fondazione Federico Calabresi The Scholarship Federico Calabresi includes a reward of 1000,00 the registration fee, travel and accommodation in Modena during the Meeting. The Scholarship will be assigned to the best publication issued on International press during the current year or in press before the date 15 th July, 2010 with a high impact factor ; the main author must be a clinical oncologist younger than 45 years old. Please send the request together with two copies of the work within July 15 th to: Accademia Nazionale di Medicina,Via Martin Piaggio 17/6, 16122 Genova - Subject: MIBCC Monica Boscolo Research Grant See attached form UniMore Award The Scientific Commitee will nominate a young researcher (< 40 years from any country) who has published an article in an International Peer-Reviewed Journal or presented at major international meetings (i.e. ASCO, ESMO) as the main author during the previous 12 months. The research must have contributed to achieve important clinical or biological advances in breast cancer. The awardee will be invited to present the results of her/his research at the Modena International Breast Cancer Conference.