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2 # # # % & # # # 5 ( & % + % " # & 6! #!! / % / / /! / / 7! # +,, + / 0 1 &" & # %! # # % # % & # # #! # #!! % : 1: 9 ; : 9 ; 9 8 #!! ( % )! 8& # 1 $ & & # # % & % 8 9 ; 1: 9 9 < 8 #!! ( % )! & 8& # 1 # % 8=! %! # % 8 ; > >? : #!! ) % / ( % )! & 8& # 1 % / % % % / 8=! %! 6! % / / 86 6! # # 8 ; > > : ; > >? 8 #!! 6 A$ 8& # 1 * / % % 8=! %! *! 86 # #!! #

3 2 - * 6 ( 6 6 ( 3 $#! " *" $#! ( " " $# # ( " " $#! ( " " $#! 6 * $# # 6 * $&$ B $" *& C $ $D & " &! & PUBBLICAZIONI O ABSTRACT $" *& C ) " )$ + $" $" 2 C C ( )&$+ $D 6 " " " & )*&" *$ " )$" &" *$ " " *" 2 & $" 6 " C " &$ &E " )= ( $ $D " + " * $" F $6 G " &" G &" 1) Primary systemic therapy in breast cancer: novel molecular marker concepts Generali D, Berruti A, Cappelletti MR, Forti M, Zanotti L, MIlani M, Ardine M, Strina C, Aguggini S, Gussago F, Zanoni V, Allevi G, Dogliotti L, Fox SB, Harris AL, Bottini A Accepted to J Natl Cancer Inst Monogr2013 2) Increased pathological complete response rate after a long-term neoadjuvant letrozole treatment in postmenopausal estrogen and/or progesterone receptor-positive breast cancer Allevi G, Strina C, Andreis D, Zanoni V, Bazzola L, Bonardi S, Foroni C, Milani M, Cappelletti MR, Gussago F, Aguggini S, Giardini R, Martinotti M, Fox SB, Harris AL, Bottini A, Berruti A, Generali D Br J Cancer 2013 Apr 30;108(8) 3) Predictive immunohistochemical biomarkers in the context of neoadjuvant therapy for breast cancer Daniele Generali, William F Symmans, Maria Rosa Cappelletti, Alfredo Berruti Stephen B Fox Accepted J Nat Cancer Inst ) Gene expression profiling in breast cancer: a clinical perspective Arpino G, Generali D, Sapino A, Lucia del M, Frassoldati A, de Laurentis M, Paolo P, Mustacchi G, Cazzaniga M, De Placido S, Conte P, Cappelletti MR, Zanoni V, Antonelli A, Martinotti M, Puglisi F, Berruti A, Bottini A, Dogliotti L Breast 2013 Apr;22(2):109-20

4 5) Pharmacogenetics of capecitabine-based treatment in advanced breast cancer patients Maria Rosa Cappelletti, Chiara Foroni, Mara Maldotti, Daniele Andreis, Letizia Bazzola, Carla Strina, Piera Bertoglio, Manuela Milani, Alberto Bottini, Daniele Generali XIII Congresso Nazionale Associazione Italiana Oncologia Medica AIOM 5-7 Novembre 2011, Bologna 6) Proof of the anti-tumour effect of zoledronic acid (za) in naive bone-only metastatic and locally advanced breast cancer (LABC): results from the "biological window therapy Chiara Foroni, Daniele Andreis, Mara Maldotti, Carla Cortellazzi, Maria Rosa Cappelletti, Ermenegilda Boni, Daniele Santini, Alfredo Berruti, Giovanna Damia, Alberto Bottini, Daniele Generali XIII Congresso Nazionale Associazione Italiana Oncologia Medica AIOM 5-7 Novembre 2011, Bologna San Antonio Breast Cancer Symposium 6-10 Dicembre ) Newsletter Diatech Pharmacogenetics: Farmacogenetica e carcinoma mammario trattato con Fluoropirimidine Maria Rosa Cappelletti, Daniele Generali, Chiara Foroni, Daniele Andreis, Mara Maldotti Dicembre ) Safety and activity of non-pegylated liposomal doxorubicin (npld) combined with oral metronomic cyclophosphamide (mc) as preoperative treatment for locally advanced breast cancer (BC) patients (pts) Daniele Andreis, Daniele Giulio Generali, Chiara Foroni, Letizia Bazzola, Maria Rosa Cappelletti, Vanessa Zanoni, Manuela Milani, Carla Strina, Giovanni Allevi, Sergio Aguggini, Ermenegilda Boni, Roberto Giardini, Ramona Bertoni, Alberto Bottini 2012 ASCO Annual Meeting June 1-5, ) Genomic predictive factors identifying toxicity in an ACTIVE non-pegylated liposomal doxorubicin (npld) -based treatment FOR locally advanced breast cancer (BC) Maria Rosa Cappelletti, Daniele Andreis, Vanessa Zanoni, Letizia Bazzola, Carla Strina, Manuela Milani, Morena Ferrari, Chiara Foroni, Alberto Bottini, Daniele Generali AIOM Ottobre 2012, Roma 10) Prospective study of positron emission tomography for evaluation of the activity of trastuzumab in HER2 positive patients with locally advanced breast tumors Carla Strina, Chiara Foroni, Daniele Andreis, Vanessa Zanoni, Maria Rosa Cappelletti, Letizia Bazzola, Manuela Milani, Ermenegilda Boni, Giovanni Allevi, Alberto Bottini, Francesco Ferrozzi, Daniele Generali AIOM Ottobre 2012, Roma 11) Neoadjuvant treatment approach: the Rosetta stone for breast cancer? Daniele Generali, Mara Ardine, Carla Strina, Manuela Milani, Maria Rosa Cappelletti, Laura Zanotti, Michela Forti, Francesca Bedussi, Mario Martinotti, Vito Amoroso, Sandra Sigala, Edda Simoncini, Alfredo Berruti, Alberto Bottini JNCI Monograph 2013

5 12) Tumor metabolism/autophagy and effect of trastuzumab on her2+ breast carcinoma in patients treated with pre-operative chemotherapy: results of a prospective study Michael I Koukourakis, Alexanda Giatromanolaki, Alberto Bottini, Maria Rosa Cappelletti, Laura Zanotti, Giovanni Allevi, Carla Strina, Mara Ardine, Manuela Milani, Giulia Brugnoli, Mario Martinotti, Giuseppina Ferrero, Ramona Bertoni, Francesco Ferrozzi, Adrian L Harris, Daniele Generali 3 '! % #! # % # # A 9 > + : 9 ; 9 +! / ) / * % " # $ H / # / #,, A :? : I ) : 9 ; 9 $ $ ) # + J ) A ; 3 # : 9 ; ; * $ / % / #, % 5'!!! K % # 6!! %!! # A : > # : 9 ; ; * 2 % D : " '! A ; 4! % : 9 ; ; $ * / % $/ % # % H! % %, A 49! % ; 6! % : 9 ; ; * $ % 1L G M / # ) % $ ; 3 " : 9 ; ; $ $ %! & % )&$& : 0 :? " : 9 ; : + % 7* $ 9 9 ; E $9 3 A " %, : : *% % : 9 ; 4* )! : 9 ; 4 $ # # 7!! # /, %!!,!! # :? : I! % : 9 ; 4! $ & % * $ ; < : 9 ) : 9 ; 4& + / ) / * % " # $ H / # / #,, A 9 0 9? " : 9 ; 4$

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