E UROPEAN CURRICULUM VITAE FORMAT

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1 E UROPEAN CURRICULUM VITAE FORMAT PERSONAL INFORMATION Name Address VALENTINA GUARNERI University of Padova Dipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologiche Istituto Oncologico Veneto IRCCS Oncologia Medica 2 Via Gattamelata Padova Nationality Italian WORK EXPERIENCE Dates (from to) Name and address of the employer Occupation or position held 01/04/2013-onwards Università di Padova Dipartimento di Scienze Chirurgiche, Oncologiche e Gastroenterologiche Istituto Oncologico Veneto IRCCS Oncologia Medica 2 Assistant Professor Dates (from to) 11/ /03/2013 Name and address of the employer Division of Medical Oncology, University Hospital, Modena Occupation or position held Assistant Professor Dates (from to) 05/ /03/2013 Name and address of the employer Division of Medical Oncology, University Hospital, Modena Occupation or position held Coordinator of the Breast Unit Dates (from to) 09-12/2009 Name and address of the employer University of Texas MD Anderson Cancer Center, Dept of Breast Medical Oncology Occupation or position held Visiting Assistant Professor Dates (from to) 01-07/2005 Name and address of the employer University of Texas MD Anderson Cancer Center, Dept of Breast Medical Oncology Occupation or position held Observer Dates (from to) Name and address of the employer Modena University Hospital Division of Oncology Page 1 - Curriculum vitae of

2 Occupation or position held Attending Physician Dates (from to) Name and adress of the employer Pisa University Hospital Occupation or position held Post-graduate Specialization, Medical Oncology ACCADEMIC POSITION Dates (from - to) 11/ /03/2013 Name and type of organisation Modena School of Medicine Principal subjects/occupational Clinical Oncology Title of qualification awarded Assistant Professor Dates (from - to) 11/ /2005 Name and type of organisation Modena School of Medicine Principal subjects/occupational Clinical Oncology Title of qualification awarded Adjunct Professor EDUCATION AND TRAINING Dates Name and type of organisation University of Modena and Reggio Emilia, Modena, Italy Title of qualification awarded post-graduation degree on "Statistics applied to clinical problems" Dates Name and type of organisation University of Modena and Reggio Emilia, Modena, Italy Principal subjects/occupational Breast cancer clinical trials with biomarker evaluation Title of qualification awarded Ph.D. Clinical and Experimental Oncology Dates Name and type of organisation Pisa University, Italy Title of qualification awarded Specialty Clinical Oncology, graduated 110/110 cum laude Date 2000 Title of qualification awarded Italian Medical Licensure Dates Name and type of organisation Pisa University, italy Title of qualification awarded M.D. degree 110/110 cum laude Page 2 - Curriculum vitae of

3 Date 1993 Name and type of organisation Liceo-Ginnasio GB Niccolini-FD Guerrazzi, Livorno,ITALY Title of qualification awarded Humanistic Bachelor Degree 60/60 MOTHER TONGUE Italian OTHER LANGUAGES Reading skills Writing skills Verbal skills English ANNEXES Formal Teaching Research Grants Committee Awards Scientific Affiliations Editorial Reviewer Board Scientific Publications Formal Teaching - Clinical Oncology, School of Medicine, University of Modena and Reggio Emilia - Clinical Oncology Speciality School, University of Modena and Reggio Emilia - Clinical Biochemistry Speciality School, University of Modena and Reggio Emilia - General Surgery Specialty School, University of Modena and Reggio Emilia - Post Doctoral Fellowship in Clinical and Experimental Oncology, University of Modena and Reggio Emilia Research Grants -Co-investigator and member of the steering committee: project Short-HER: multicentric randomised phase III trial of 2 different adjuvant chemotherapy regimens plus 3 vs 12 months of trastuzumab in HER2 positive breast cancer patients. Research grant from Agenzia Italiana del Farmaco (AIFA , extended 2010) (PI Prof Conte) - Co-Investigator: Primary systemic therapy for early breast cancer: clinical, biological and molecular outputs (PRIN , project # ). - Co-investigator and member of the steering committee: project Chemotherapy plus lapatinib or trastuzumab or both in HER2 + primary breast cancer. A randomized phase IIb study with biomarker evaluation. (PI Prof Conte) -Co-investigator and member of the steering committee: project Letrozole versus letrozole plus lapatinib in hormone-sensitive, HER2-2 negative operable breast cancer. A double blind randomized phase II study with biomarker evaluation (PI Prof Conte) -Co-investigator: Proteomic, genomic and biomarker expression as predictor of response to chemotherapy and molecularly targeted agents in breast cancer patients treated with preoperative therapy. Progetti Integrati Oncologia 2006 (project 04/07). Page 3 - Curriculum vitae of

4 International collaborations: - cooperation with Military institute of Medicine in Varsaw, to develop a gene expression profile able to predict the risk of developing brain metastases in HER2 + breast cancer patients (project coordinated by Dr Renata Duchnowska) -Collaboration with prof A. Lipton, Penn State University, Pennsylvenia, USA, in the evaluation of HER2 dimers expression from primary tumor to metastases in breast cancer patients -Cooperation with UT MD Anderson cancer center for the evaluation of the prognostic role of post-therapy Ki67 in breast cancer patients treated with neoadjuvant chemotherapy (Prof. AM Gonzalez-Angulo) Commitee - ESMO Young Oncologists Committee , renewed ESMO E-learning and CME Working Group: since 2010: member of the International Congress on Anticancer Treatment (ICACT) Scientific Committee - AIOM National Congress Scientific Committee: 2008; 2012: referee for breast cancer Awards Award from Ordine dei Medici di Livorno for the best MD degree thesis : Research grant from Komen foundation Italy- Università Cattolica del Sacro Cuore di Roma for research project to be completed at the University of Texas, MD Anderson Cancer Center, Houston, Texas (Prof GN Hortobagyi) : Research award from Lega Italiana per la Lotta contro i Tumori : Young Researcher Award from Associazione Malati Oncologici : Young Researcher Award from voluntary association Cestodiciliege : Young Researcher Award from voluntary association Cestodiciliege -2009: Travel Grant from Fondazione Komen ( Prognostic role of Ki67 following preoperative chemotherapy -MD Anderson Cancer Center, Houston, Texas) : Awardee of the Unimore Monica Boscolo Research Grant (Residual tumor after preoperative chemotherapy in breast cancer as a model to study resistant micrometastatic disease) -2013: Young Researcher Award, Fondazione Guido Berlucchi Scientific Affiliations - Italian Association Medical Oncology (AIOM) - European Society Medical Oncology (ESMO) - American Society Clinical Oncology (ASCO) - EBMT (European Bone Marrow Transplantation) Editorial Reviewer Board - Annals of Oncology - Clinical Cancer Research - The Oncologist - Breast Cancer Research - British Journal of Cancer - Clinical Breast Cancer - Annals of Surgical Oncology - American Journal of Clinical Oncology - Cancer Letters Page 4 - Curriculum vitae of

5 - Expert Opinion on Drug Safety - Expert Review of Anticancer Therapy - Expert opinion on Pharmacotherapy - Cancer Chemotherapy and Pharmacology - International Journal of Biomedical Science - Chemotherapy - Oncology - Journal of Oncology Publications: Author or co-author of 62 full-text paper in peer-reviewed. Total Impact Factor:262, IF as first or last author: 152 (JCR-ISI WEB 2012). H Index : 22 (Anne-Wil Harzing) She is author of 4 book chapters, and co-author of 2 book chapters. Page 5 - Curriculum vitae of