Advanced Gateway Destination Vectors



Similar documents
NIH Mammalian Gene Collection (MGC)

Bacterial Transformation with Green Fluorescent Protein. Table of Contents Fall 2012

One Shot TOP10 Competent Cells

Transformation Protocol

The Awesome Power of Yeast Genetics: Spontaneous and Induced Mutagenesis and Complementation Analysis using Saccharomyces cerevisiae.

MGC premier Expression-Ready cdna clones TCH1103, TCM1104, TCR1105, TCB1106, TCH1203, TCM1204, TCR1205, TCB1206, TCH1303, TCM1304, TCR1305

Proto col. GoClone Repor ter Construc ts: Sample Protocol for Adherent Cells. Tech support: Luciferase Assay System

Transformation of the bacterium E. coli. using a gene for Green Fluorescent Protein

Frozen-EZ Yeast Transformation II Catalog No. T2001

Molecular Biology. Yeast Transformation. Yeast Plasmids. Gene Disruption, tagging. Cloning by Complementation. Epistasis

Recombinant DNA Technology

Green Fluorescent Protein (GFP): Genetic Transformation, Synthesis and Purification of the Recombinant Protein

Arabidopsis. A Practical Approach. Edited by ZOE A. WILSON Plant Science Division, School of Biological Sciences, University of Nottingham

TransformAid Bacterial Transformation Kit

INTERNATIONAL CONFERENCE ON HARMONISATION OF TECHNICAL REQUIREMENTS FOR REGISTRATION OF PHARMACEUTICALS FOR HUMAN USE Q5B

Cloning GFP into Mammalian cells

BaculoDirect Baculovirus Expression System Free your hands with the BaculoDirect Baculovirus Expression System

Laboratory Biosafty In Molecular Biology and its levels

pcas-guide System Validation in Genome Editing

Molecular Biology Techniques: A Classroom Laboratory Manual THIRD EDITION

Transfection-Transfer of non-viral genetic material into eukaryotic cells. Infection/ Transduction- Transfer of viral genetic material into cells.

2D gel Protocol. 2. Determining Protein Concentration of cell lysates

Recombinant DNA and Biotechnology

Agrobacterium tumefaciens-mediated transformation of Colletotrichum graminicola and Colletotrichum sublineolum

Product: Expression Arrest TM egfp control shrna vector

from Cloned Genes Learning outcomes: By the end of this chapter you will have an understanding of:

European Medicines Agency

Recombinant DNA Unit Exam

Protein Expression. A Practical Approach J. HIGGIN S

Chapter 11. Rapid Screening of Gli2/3 Mutants Using the Flp-In System. Pawel Niewiadomski and Rajat Rohatgi. Abstract.

How To Get Rid Of Small Dna Fragments

Description: Molecular Biology Services and DNA Sequencing

Bio-Reagents Gene synthesis Peptide Synthesis Protein Expression Antibody Production. Life Science Products and Services

Inc. Wuhan. Quantity Pre-coated, ready to use 96-well strip plate 1 Plate sealer for 96 wells 4 Standard (liquid) 2

EXPRESSION ARREST shrna mir GENOME- WIDE LIBRARIES

National Food Safety Standard Food microbiological examination: Aerobic plate count

Medical or Biological Waste: Storage, Treatment, Disposal and Transportation Plan

Genetomic Promototypes

Investigating a Eukaryotic Genome: Cloning and Sequencing a Fragment of Yeast DNA

Transferring a Broth Culture to Fresh Broth

Rat creatine kinase MM isoenzyme (CK-MM) ELISA Kit

FOR REFERENCE PURPOSES

Molecular and Cell Biology Laboratory (BIOL-UA 223) Instructor: Ignatius Tan Phone: Office: 764 Brown

PRODUCT INFORMATION...

DNA Sample preparation and Submission Guidelines

Bacillus Subtilis Expression Vectors. Product Information and Instructions November 2005

Rat creatine kinase MM isoenzyme (CK-MM) ELISA Kit

pmod2-puro A plasmid containing a synthetic Puromycin resistance gene Catalog # pmod2-puro For research use only Version # 11H29-MM

LAB 16 Rapid Colony Transformation of E. coli with Plasmid DNA

Bacterial Transformation and Plasmid Purification. Chapter 5: Background

Gene Cloning. Reference. T.A. Brown, Gene Cloning, Chapman and Hall. S.B. Primrose, Molecular Biotechnology, Blackwell

CHAPTER 6: RECOMBINANT DNA TECHNOLOGY YEAR III PHARM.D DR. V. CHITRA

Biotechnology and Recombinant DNA (Chapter 9) Lecture Materials for Amy Warenda Czura, Ph.D. Suffolk County Community College

Transformation Kit BACTERIAL TRANSFORMATION: GREEN FLUORESCENT PROTEIN. Partnership for Biotechnology and Genomics Education

TECHNIQUES IN MOLECULAR BIOLOGY BASIC E. COLI INFORMATION FOR MOLECULAR BIOLOGY

Effects of Antibiotics on Bacterial Growth and Protein Synthesis: Student Laboratory Manual

LightSwitch Dual Assay System DA010 (100 assays)

UCCS Biosafety Management Policy

Mouse Creatine Kinase MB isoenzyme (CKMB) ELISA

SAMPLE. Bacterial Transformation. Lab 8 BACKGROUND INFORMATION. Neo/SCI Student s Guide Name... Teacher/Section...

Zeocin Selection Reagent

A Guide to Managing Your Biological Waste at the University at Albany

Clones ORFs cdna Proteins Tags Vectors Markers Etc.

Rat Creatine Kinase MB Isoenzyme (CKMB) ELISA

Canine creatine kinase MB isoenzyme (CK-MB)ELISA Kit

DNA CAN BE TRANSFERRED BETWEEN BACTERIA GENETIC ENGINEERING USING RECOMBINANT DNA TECHNOLOGY

LAB 7 DNA RESTRICTION for CLONING

DNA SEQUENCING SANGER: TECHNICALS SOLUTIONS GUIDE

restriction enzymes 350 Home R. Ward: Spring 2001

Policies. Prep Room Policies

HiPer RT-PCR Teaching Kit

Protease Peptide Microarrays Ready-to-use microarrays for protease profiling

GROWING BACTERIA INTRODUCTION

Colorful choices for your bright ideas

MEF Starter Nucleofector Kit

GENETIC TRANSFORMATION OF BACTERIA WITH THE GENE FOR GREEN FLUORESCENT PROTEIN (GFP)

Transfection reagent for visualizing lipofection with DNA. For ordering information, MSDS, publications and application notes see

Integrated Protein Services

SpikeTides TM Peptides for relative and absolute quantification in SRM and MRM Assays

For information regarding shipping specifications, please refer to the following link:

Rat Creatine Kinase MB isoenzyme,ck-mb ELISA Kit

Epitope Tag. Tag Antibodies and Kits. Epitope TAG. Myc-Tag Antibodies. For Research Only. Functional Tag.

Biotechnology: DNA Technology & Genomics

Compiled and/or written by Amy B. Vento and David R. Gillum

HCS Exercise 1 Dr. Jones Spring Recombinant DNA (Molecular Cloning) exercise:

Cell Culture Protocol for Biogelx Peptide Hydrogel 2D and 3D Cell Culture PRO/BGX/001

Chromatin Immunoprecipitation

Computer 6B. Forensic DNA Fingerprinting

Sanger Sequencing. Troubleshooting Guide. Failed sequence

AMES TEST: Bacterial Reverse Mutation Assay

ptune Inducible Vector

Human Free Testosterone(F-TESTO) ELISA Kit

Uscn Life Science Inc. Wuhan

A STUDY ON THE EFFECTIVENESS OF PEER TUTORING AS A TEACHING METHOD IN HIGH SCHOOL BIOTECHNOLOGY LABS. June Camerlengo. Santa Fe High School

University of Colorado at Boulder

Transcription:

Description: The Susan Lindquist laboratory of the Howard Hughes Medical Institute and the Whitehead Institute for Biomedical Research has deposited a set of Gateway destination vectors for highthroughput genetic analysis in S. cerevisiae. The plasmids are divided into three plates. Detailed information can be found at: www.addgene.org/yeast_gateway Reference: A suite of Gateway cloning vectors for high-throughput genetic analysis in Saccharomyces cerevisiae. Simon Alberti, Aaron D. Gitler, and Susan Lindquist. Yeast, 2007. Handling and Storage: Store glycerol stocks at -80 o C and minimize freeze-thaw cycles. To access a plasmid, keep the plate on dry ice to prevent thawing. Using a sterile pipette tip, puncture the seal above an individual well and spread a portion of the glycerol stock onto an agar plate. To patch the hole, use sterile tape or a portion of a fresh aluminum seal. Note: These plasmid constructs are being distributed to non-profit institutions for the purpose of basic research. Please contact Susan Lindquist to determine proper attribution on any publications arising from the use of these plasmids. Please contact Addgene at help@addgene.org with any questions. www.addgene.org help@addgene.org

Plate 3 GAL1 GPD No tag ECFP EGFP EYFP Cerulean Integrating CEN 2 µ attr1 attr2 padvancedgateway Destination Vector No tag ECFP EGFP EYFP DsRed Cerulean HA TAP HIS3 TRP1 LEU2 URA3 Plate 1 Plate 2 Alberti et al., Yeast 2007 The set of padvancedgateway Destination Vectors allows for a choice of: 1. Promoter: constitutive (GPD) or inducible (GAL1) 2. N-terminal protein tag: ECFP, EGFP, EYFP, Cerulean 3. C-terminal protein tag: ECFP, EGFP, EYFP, DsRed, Cerulean, HA, TAP 4. Integrating or extra-chromosomal: Integrating: pag303, 304, 305, 306 Low-copy number (CEN): pag413, 414, 415, 416 High-copy number (2µ): pag423, 424, 425, 426 5. Selectable marker: HIS3: pag303, 413, 423 TRP1: pag304, 414, 424 LEU2: pag305, 415, 425 URA3: pag306, 416, 426 * Please see individual plasmid pages for detailed maps and full sequences.

Plate 1 A 303GAL-ccdB 413GAL-ccdB 423GAL-ccdB 303GAL-ccdB-ECFP 413GAL-ccdB-ECFP 423GAL-ccdB-ECFP B 303GPD-ccdB 413GPD-ccdB 423GPD-ccdB 303GPD-ccdB-ECFP 413GPD-ccdB-ECFP 423GPD-ccdB-ECFP C 304GAL-ccdB 414GAL-ccdB 424GAL-ccdB 304GAL-ccdB-ECFP 414GAL-ccdB-ECFP 424GAL-ccdB-ECFP D 304GPD-ccdB 414GPD-ccdB 424GPD-ccdB 304GPD-ccdB-ECFP 414GPD-ccdB-ECFP 424GPD-ccdB-ECFP E 305GAL-ccdB 415GAL-ccdB 425GAL-ccdB 305GAL-ccdB-ECFP 415GAL-ccdB-ECFP 425GAL-ccdB-ECFP F 305GPD-ccdB 415GPD-ccdB 425GPD-ccdB 305GPD-ccdB-ECFP 415GPD-ccdB-ECFP 425GPD-ccdB-ECFP G 306GAL-ccdB 416GAL-ccdB 426GAL-ccdB 306GAL-ccdB-ECFP 416GAL-ccdB-ECFP 426GAL-ccdB-ECFP H 306GPD-ccdB 416GPD-ccdB 426GPD-ccdB 306GPD-ccdB-ECFP 416GPD-ccdB-ECFP 426GPD-ccdB-ECFP A 303GAL-ccdB-EGFP 413GAL-ccdB-EGFP 423GAL-ccdB-EGFP 303GAL-ccdB-EYFP 413GAL-ccdB-EYFP 423GAL-ccdB-EYFP B 303GPD-ccdB-EGFP 413GPD-ccdB-EGFP 423GPD-ccdB-EGFP 303GPD-ccdB-EYFP 413GPD-ccdB-EYFP 423GPD-ccdB-EYFP C 304GAL-ccdB-EGFP 414GAL-ccdB-EGFP 424GAL-ccdB-EGFP 304GAL-ccdB-EYFP 414GAL-ccdB-EYFP 424GAL-ccdB-EYFP D 304GPD-ccdB-EGFP 414GPD-ccdB-EGFP 424GPD-ccdB-EGFP 304GPD-ccdB-EYFP 414GPD-ccdB-EYFP 424GPD-ccdB-EYFP E 305GAL-ccdB-EGFP 415GAL-ccdB-EGFP 425GAL-ccdB-EGFP 305GAL-ccdB-EYFP 415GAL-ccdB-EYFP 425GAL-ccdB-EYFP F 305GPD-ccdB-EGFP 415GPD-ccdB-EGFP 425GPD-ccdB-EGFP 305GPD-ccdB-EYFP 415GPD-ccdB-EYFP 425GPD-ccdB-EYFP G 306GAL-ccdB-EGFP 416GAL-ccdB-EGFP 426GAL-ccdB-EGFP 306GAL-ccdB-EYFP 416GAL-ccdB-EYFP 426GAL-ccdB-EYFP H 306GPD-ccdB-EGFP 416GPD-ccdB-EGFP 426GPD-ccdB-EGFP 306GPD-ccdB-EYFP 416GPD-ccdB-EYFP 426GPD-ccdB-EYFP

Plate 2 A 303GAL-ccdB-DsRed 413GAL-ccdB-DsRed 423GAL-ccdB-DsRed 303GAL-ccdB-Cer 413GAL-ccdB-Cer 423GAL-ccdB-Cer B 303GPD-ccdB-DsRed 413GPD-ccdB-DsRed 423GPD-ccdB-DsRed 303GPD-ccdB-Cer 413GPD-ccdB-Cer 423GPD-ccdB-Cer C 304GAL-ccdB-DsRed 414GAL-ccdB-DsRed 424GAL-ccdB-DsRed 304GAL-ccdB-Cer 414GAL-ccdB-Cer 424GAL-ccdB-Cer D 304GPD-ccdB-DsRed 414GPD-ccdB-DsRed 424GPD-ccdB-DsRed 304GPD-ccdB-Cer 414GPD-ccdB-Cer 424GPD-ccdB-Cer E 305GAL-ccdB-DsRed 415GAL-ccdB-DsRed 425GAL-ccdB-DsRed 305GAL-ccdB-Cer 415GAL-ccdB-Cer 425GAL-ccdB-Cer F 305GPD-ccdB-DsRed 415GPD-ccdB-DsRed 425GPD-ccdB-DsRed 305GPD-ccdB-Cer 415GPD-ccdB-Cer 425GPD-ccdB-Cer G 306GAL-ccdB-DsRed 416GAL-ccdB-DsRed 426GAL-ccdB-DsRed 306GAL-ccdB-Cer 416GAL-ccdB-Cer 426GAL-ccdB-Cer H 306GPD-ccdB-DsRed 416GPD-ccdB-DsRed 426GPD-ccdB-DsRed 306GPD-ccdB-Cer 416GPD-ccdB-Cer 426GPD-ccdB-Cer A 303GAL-ccdB-HA * 413GAL-ccdB-HA 423GAL-ccdB-HA 303GAL-ccdB-TAP 413GAL-ccdB-TAP 423GAL-ccdB-TAP B 303GPD-ccdB-HA * 413GPD-ccdB-HA 423GPD-ccdB-HA 303GPD-ccdB-TAP 413GPD-ccdB-TAP 423GPD-ccdB-TAP C 304GAL-ccdB-HA * 414GAL-ccdB-HA 424GAL-ccdB-HA 304GAL-ccdB-TAP 414GAL-ccdB-TAP 424GAL-ccdB-TAP D 304GPD-ccdB-HA * 414GPD-ccdB-HA 424GPD-ccdB-HA 304GPD-ccdB-TAP 414GPD-ccdB-TAP 424GPD-ccdB-TAP E 305GAL-ccdB-HA 415GAL-ccdB-HA 425GAL-ccdB-HA 305GAL-ccdB-TAP 415GAL-ccdB-TAP 425GAL-ccdB-TAP F 305GPD-ccdB-HA 415GPD-ccdB-HA 425GPD-ccdB-HA 305GPD-ccdB-TAP 415GPD-ccdB-TAP 425GPD-ccdB-TAP G 306GAL-ccdB-HA * 416GAL-ccdB-HA 426GAL-ccdB-HA 306GAL-ccdB-TAP 416GAL-ccdB-TAP 426GAL-ccdB-TAP H 306GPD-ccdB-HA * 416GPD-ccdB-HA 426GPD-ccdB-HA 306GPD-ccdB-TAP 416GPD-ccdB-TAP 426GPD-ccdB-TAP * : missing CYC1 terminator

Plate 3 A 303GAL-ECFP-ccdB 413GAL-ECFP-ccdB 423GAL-ECFP-ccdB 303GAL-EGFP-ccdB 413GAL-EGFP-ccdB 423GAL-EGFP-ccdB B 303GPD-ECFP-ccdB 413GPD-ECFP-ccdB 423GPD-ECFP-ccdB 303GPD-EGFP-ccdB 413GPD-EGFP-ccdB 423GPD-EGFP-ccdB C 304GAL-ECFP-ccdB 414GAL-ECFP-ccdB 424GAL-ECFP-ccdB 304GAL-EGFP-ccdB 414GAL-EGFP-ccdB 424GAL-EGFP-ccdB D 304GPD-ECFP-ccdB 414GPD-ECFP-ccdB 424GPD-ECFP-ccdB 304GPD-EGFP-ccdB 414GPD-EGFP-ccdB 424GPD-EGFP-ccdB E 305GAL-ECFP-ccdB 415GAL-ECFP-ccdB 425GAL-ECFP-ccdB 305GAL-EGFP-ccdB 415GAL-EGFP-ccdB 425GAL-EGFP-ccdB F 305GPD-ECFP-ccdB 415GPD-ECFP-ccdB 425GPD-ECFP-ccdB 305GPD-EGFP-ccdB 415GPD-EGFP-ccdB 425GPD-EGFP-ccdB G 306GAL-ECFP-ccdB 416GAL-ECFP-ccdB 426GAL-ECFP-ccdB 306GAL-EGFP-ccdB 416GAL-EGFP-ccdB 426GAL-EGFP-ccdB H 306GPD-ECFP-ccdB 416GPD-ECFP-ccdB 426GPD-ECFP-ccdB 306GPD-EGFP-ccdB 416GPD-EGFP-ccdB 426GPD-EGFP-ccdB A 303GAL-EYFP-ccdB 413GAL-EYFP-ccdB 423GAL-EYFP-ccdB 303GAL-Cer-ccdB 413GAL-Cer-ccdB 423GAL-Cer-ccdB B 303GPD-EYFP-ccdB 413GPD-EYFP-ccdB 423GPD-EYFP-ccdB 303GPD-Cer-ccdB 413GPD-Cer-ccdB 423GPD-Cer-ccdB C 304GAL-EYFP-ccdB 414GAL-EYFP-ccdB 424GAL-EYFP-ccdB 304GAL-Cer-ccdB 414GAL-Cer-ccdB 424GAL-Cer-ccdB D 304GPD-EYFP-ccdB 414GPD-EYFP-ccdB 424GPD-EYFP-ccdB 304GPD-Cer-ccdB 414GPD-Cer-ccdB 424GPD-Cer-ccdB E 305GAL-EYFP-ccdB 415GAL-EYFP-ccdB 425GAL-EYFP-ccdB 305GAL-Cer-ccdB 415GAL-Cer-ccdB 425GAL-Cer-ccdB F 305GPD-EYFP-ccdB 415GPD-EYFP-ccdB 425GPD-EYFP-ccdB 305GPD-Cer-ccdB 415GPD-Cer-ccdB 425GPD-Cer-ccdB G 306GAL-EYFP-ccdB 416GAL-EYFP-ccdB 426GAL-EYFP-ccdB 306GAL-Cer-ccdB 416GAL-Cer-ccdB 426GAL-Cer-ccdB H 306GPD-EYFP-ccdB 416GPD-EYFP-ccdB 426GPD-EYFP-ccdB 306GPD-Cer-ccdB 416GPD-Cer-ccdB 426GPD-Cer-ccdB : missing portion of the Gal1 promoter