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Combat Casualty Care Lessons Learned from OEF and OIF Edited by Eric Savitsky, MD Colonel Brian Eastridge, MD Pelagique, LLC Los Angeles, California University of California at Los Angeles Los Angeles, California Office of The Surgeon General United States Army, Falls Church, Virginia AMEDD Center & School Fort Sam Houston, Texas Borden Institute Fort Detrick, Maryland

Combat Casualty Care Lessons Learned from OEF and OIF Published by the Office of the Surgeon General Department of the Army, United States of America Editor in Chief Martha K. Lenhart, MD, PhD Colonel, MC, US Army Director, Borden Institute Assistant Professor of Surgery F. Edward Hébert School of Medicine Uniformed Services University of the Health Sciences Medical Content Editor Eric Savitsky, MD UCLA Professor of Emergency Medicine/Pediatric Emergency Medicine Executive Director, UCLA Center for International Medicine Director, UCLA EMC Trauma Services and Education Military Editor Brian Eastridge, MD, FACS Colonel, MC, US Army Trauma and Surgical Critical Care Director, Joint Trauma System Program Trauma Consultant, US Army Surgeon General

Combat Casualty Care Lessons Learned from OEF and OIF Editors Eric Savitsky, MD Colonel Brian Eastridge, MD Associate Editors Dan Katz, MD Richelle Cooper, MD Office of The Surgeon General United States Army Falls Church, Virginia AMEDD Center & School Fort Sam Houston, Texas Borden Institute Fort Detrick, Maryland 2012 Weapons Effects iii

Editorial Staff: borden institute pelagique, llc Vivian Mason Dan Katz, MD Technical Editor Associate Medical Editor Douglas Wise Senior Layout Editor Bruce Maston Visual Information Specialist UCLA Richelle Cooper, MD Research Methodology Editor pelagique, llc Nicole Durden, MPP Digital Media Editor pelagique, llc Koren Bertolli, MIA Copy Editor This volume was prepared for military medical educational use. The focus of the information is to foster discussion that may form the basis of doctrine and policy. The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense. Dosage Selection: The authors and publisher have made every effort to ensure the accuracy of dosages cited herein. However, it is the responsibility of every practitioner to consult appropriate information sources to ascertain correct dosages for each clinical situation, especially for new or unfamiliar drugs and procedures. The authors, editors, publisher, and the Department of Defense cannot be held responsible for any errors found in this book. Use of Trade or Brand Names: Use of trade or brand names in this publication is for illustrative purposes only and does not imply endorsement by the Department of Defense. Neutral Language: Unless this publication states otherwise, masculine nouns and pronouns do not refer exclusively to men. certain parts of this publication pertain to copyright restrictions. all rights reserved. no copyrighted parts of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical (including photocopy, recording, or any information storage and retrieval system), without permission in writing from the publisher or copyright owner. Published by the Office of The Surgeon General Borden Institute Fort Detrick, MD 21702-5000 Library of Congress Cataloging-in-Publication Data Combat casualty care : lessons learned from OEF and OIF / editor-in-chief, Martha K. Lenhart; medical editor, Eric Savitsky; military editor, Brian Eastridge. p. ; cm. Includes bibliographical references and index. I. Lenhart, Martha K. II. Savitsky, Eric. III. Eastridge, Brian. IV. United States. Dept. of the Army. Office of the Surgeon General. V. Borden Institute (U.S.) [DNLM: 1. Military Medicine--methods. 2. Wounds and Injuries--surgery. 3. Afghan Campaign 2001-. 4. Iraq War, 2003-2011. 5. War. WO 800] 616.9 8023--dc23 2011032530 PRINTED IN THE UNITED STATES OF AMERICA iv 19, Combat 18, 17, 16, Casualty 15, 14, 13, 12 Care 5 4 3 2 1

Contents Contributors...vii Photo Contributors...viii Acknowledgments...ix Preface...xi Prologue...xiii Chapter 1 Chapter 2 Chapter 3 Chapter 4 Chapter 5 Chapter 6 Chapter 7 Chapter 8 Chapter 9 Modern Warfare...1 Alec C. Beekley, Harold Bohman, and Danielle Schindler Weapons Effects...39 Sidney B. Brevard, Howard Champion, and Dan Katz Fundamentals of Combat Casualty Care...85 Robert T. Gerhardt, Robert L. Mabry, Robert A. De Lorenzo, and Frank K. Butler Damage Control Resuscitation...121 Jeremy G. Perkins and Alec C. Beekley Damage Control Surgery...165 Brian J. Eastridge, Lorne H. Blackbourne, Todd Rasmussen, Henry Cryer, and Alan Murdock Maxillofacial and Neck Trauma...225 Robert G. Hale, David K. Hayes, George Orloff, Kyle Peterson, David B. Powers, and Swaminatha Mahadevan Ocular Trauma...299 Raymond I. Cho and Eric Savitsky Traumatic Brain Injury...343 Scott A. Marshall, Randy Bell, Rocco A. Armonda, Eric Savitsky, and Geoffrey S. F. Ling Extremity Injury...393 John F. Kragh, Jr., Jess M. Kirby, and James R. Ficke Chapter 10 Spinal Trauma...485 Raymond F. Topp, Eric Savitsky, and William P. Cranston Chapter 11 Pediatric Trauma...529 Philip C. Spinella, Jonathan Martin, and Kenneth S. Azarow Weapons Contents Effects v

Chapter 12 Acute Burn Care...593 Evan M. Renz and Leopoldo C. Cancio Chapter 13 Critical Care...639 David Norton, Phillip Mason, and Jay Johannigman Abbreviations and Acronyms...xv Index...xxi vi Combat Casualty Care

Contributors Rocco A. Armonda, MD, LTC, MC, US Army Kenneth S. Azarow, MD, FACS, FAAP, COL (Ret), MC, US Army Alec C. Beekley, MD, FACS, LTC, MC, US Army Randy Bell, MD John Belperio, MD Lorne H. Blackbourne, MD, COL, MC, US Army Harold Bohman, MD, CAPT, MC, US Navy Sidney B. Brevard, MD, MPH, FACS, COL, US Air Force Frank K. Butler, MD, FACS, CAPT (Ret), US Navy Leopoldo C. Cancio, MD, FACS, COL, MC, US Army Howard Champion, MD, FRCS, FACS Raymond I. Cho, MD, LTC, MC, US Army William P. Cranston, PA, CPT, SP, US Army Henry Cryer, MD Robert A. De Lorenzo, MD, MSM, FACEP, COL, US Army Brian J. Eastridge, MD, COL, MC, US Army James R. Ficke, MD, COL, MC, US Army Gelareh Gabayan, MD Robert T. Gerhardt, MD, MPH, FACEP, FAAEM, LTC, US Army Robert G. Hale, DDS, COL, US Army David K. Hayes, MD, COL, US Army John Hiatt, MD Jay Johannigman, MD, COL, US Air Force Reserve Dan Katz, MD Jess M. Kirby, MD, MAJ, MC, US Army John F. Kragh, Jr., MD, COL, MC, US Army Geoffrey S. F. Ling, MD, PhD, COL, US Army Robert L. Mabry, MD, FACEP, MAJ(P), US Army Swaminatha Mahadevan, MD Scott A. Marshall, MD Jonathan Martin, MD Phillip Mason, MD, MAJ, US Air Force Alan Murdock, MD, LTC, US Air Force David Norton, MD, LTC, MC, US Air Force George Orloff, MD Jeremy G. Perkins, MD, FACP, LTC, MC, US Army Kyle Peterson, DO, CDR, US Navy David B. Powers, DMD, MD, COL, US Air Force Todd Rasmussen, MD, LTC, US Air Force Evan M. Renz, MD, FACS, LTC(P), MC, US Army Eric Savitsky, MD Danielle Schindler, MD Philip C. Spinella, MD Areti Tillou, MD, MsED, FACS Raymond F. Topp, MD, LTC, MC, US Army Lee Ann Young, BSME, MA Weapons Contributors Effects vii

Photo Contributors We thank the following individuals and organizations for providing some of the images used in this book. American Academy of Neurology Practice Parameter on Management of Concussions Applied Research Associates, Inc. Harold Bohman, MD, CAPT, MC, US Navy Borden Institute, Office of The Surgeon General, Washington, DC David Burris, MD, COL, MC, US Army Leopoldo C. Cancio, MD, FACS, COL, MC, US Army David Carmack, MD Center for Sustainment of Trauma and Readiness Skills (C-STARS) Combat Medical Systems Composite Resources, Inc. Subrato Deb, MD, CDR Defense Imagery Management Operations Center (DIMOC) Defense-Update.com Delfi Medical Innovations, Inc. Robert H. Demling, MD, Harvard Medical School DJO, LLC Brian J. Eastridge, MD, FACS, COL, US Army Elsevier James R. Ficke, MD, COL, MC, US Army J. Christian Fox, MD, University of California Irvine Aletta Frazier, MD, Illustrator GlobalSecurity.org Mitchell Goff, MD Tamer Goksel, DDS, MD, COL, US Army Chris Gralapp, Illustrator Robert R. Granville, MD, COL, MC, US Army Kurt W. Grathwohl, MD, COL, MC, US Army Timothy Hain, MD, Northwestern University Robert G. Hale, DDS, COL, US Army John B. Holcomb, MD, COL (Ret), MC, US Army icasualties.org Joint Combat Trauma Management Course, 2007 Joint Theater Trauma Registry Joint Theater Trauma Systems Program, US Army Institute of Surgical Research Dan Katz, MD Glenn J. Kerr, MD, MAJ, MC, US Army John F. Kragh, Jr., MD, COL, MC, US Army Donald C. Kowalewski, LTC, MC, US Air Force LearningRadiology.com Gene Liu, MD, Cedars-Sinai Medical Center Michael Shaun Machen, MD, COL, MC, US Army Swaminatha V. Mahadevan, MD, Stanford University Jonathan Martin, MD, Connecticut Children s Medical Center Massachusetts Medical Society Bruce Maston, Illustrator Alan Murdock, MD, LTC, US Air Force Juan D. Nava, Medical Illustrator, Brooke Army Medical Center Joel Nichols, MD North American Rescue, LLC David Norton, MD, LTC, MC, US Air Force Pelagique, LLC Pelvic Binder, Inc. David B. Powers, DMD, MD, COL, US Air Force Rady Rahban, MD Todd Rasmussen, MD, LTC, US Air Force Reichert Technologies Evan M. Renz, MD, FACS, LTC(P), MC, US Army Jessica Shull, Illustrator Philip C. Spinella, MD Stryker Instruments Raymond F. Topp, MD, LTC, MC, US Army Trauma.org UCLA Center for International Medicine United Nations Mine Action Service University of Michigan Kellogg Eye Center Eric D. Weichel, MD Wikimedia Commons viii Combat Casualty Care

Acknowledgments We extend our gratitude to Robert (Bob) Foster, Director of Biosystems (Ret), Office of the Director, Defense Research and Engineering; and Colonel (Ret) John Holcomb for their vision and guidance in support of this project. This educational effort was made possible through the Defense Health Program Small Business Innovation Research (SBIR) Program and Telemedicine and Advanced Technology and Research Center (TATRC). A special thanks to Colonel Lorne Blackbourne (USAISR), Colonel Karl Friedl (TATRC), and Jessica Kenyon (TATRC) for their support and guidance throughout this effort. Acknowledgments Weapons Effects ix

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Preface To enhance combat casualty care (CCC) pre-deployment education for all healthcare providers, this contemporary educational program was developed through the Small Business Innovative Research Program in partnership with civilian industry and the Office of the Secretary of Defense for Health Affairs. This military medicine textbook is designed to deliver CCC information that will facilitate transition from a continental United States (CONUS) or civilian practice to the combat care environment. Establishment of the Joint Theater Trauma System (JTTS) and the Joint Theater Trauma Registry (JTTR), coupled with the efforts of the authors, has resulted in the creation of the most comprehensive, evidence-based depiction of the latest advances in CCC. Lessons learned in Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) have been fortified with evidence-based recommendations with the intent of improving casualty care. The chapters specifically discuss differences between CCC and civilian sector care, particularly in the scheme of echelonized care. Overall, the educational curriculum was designed to address the leading causes of preventable death and disability in OEF and OIF. Specifically, the generalist CCC provider is presented requisite information for optimal care of US combat casualties in the first 72 to 96 hours after injury. The specialist CCC provider is afforded similar information, which is supplemented by lessons learned for definitive care of host nation patients. These thirteen peer-reviewed and well-referenced chapters were authored by military subject matter experts with extensive hands-on experience providing CCC during the course of OEF and OIF, and were edited by an experienced team of physicians and research methodologists. Together they will provide readers with a solid understanding of the latest advances in OEF and OIF CCC. This information provides an excellent supplement to pre-deployment CCC training and education. Ideally, readers will aptly apply the newly acquired knowledge toward improving CCC. Los Angeles, CA June 2011 Eric Savitsky, MD UCLA Professor of Emergency Medicine/Pediatric Emergency Medicine Executive Director, UCLA Center for International Medicine Director, UCLA EMC Trauma Services and Education Weapons Preface Effects xi

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Prologue War is Hell. William Tecumseh Sherman The battlefield will challenge your medical skills, knowledge, personal courage, and perseverance. However, in the end, you and the Wounded Warrior will be better for it. It is 0200. You are on a forward operating base in the high desert somewhere in southwest Asia. The radio in the TOC (Tactical Operations Center) crackles to life, breaking the silence of the night: This is Whiskey Foxtrot Tango Niner. Inbound in six mikes with two urgent surgicals from an IED. Requesting a hot offload TIC in progress more casualties to pick up. Over. Outside of the resuscitation area, over the whisper of the cold wind, you hear the whir of the rotor blades of the approaching MEDEVAC Blackhawks. Setting down on the landing zone with a deafening roar, all you can see is the static electrical discharge from the spinning rotors. Appearing from the darkness are wheeled litter carriers bearing casualties and teams of attendants racing alongside. Now, it s your turn. This is our calling, the reason we are here for the Warrior. The content of this book was composed for you by those who have been in your boots. Similar situations have played out over 47,000 times for US military combat casualties. Survival from injury on the modern battlefield is unprecedented; the current case fatality rate is 11%. This is even more astonishing, considering the complexity of injury and evacuation of casualties through multiple levels of care across the globe. Throughout history, armed conflict has shaped advances in medicine and surgery. These conflicts are no different. However, with the progress of technology and communication, we are better able to potentiate and disseminate recent lessons learned. The paradigm of tactical combat casualty care has dramatically altered pre-hospital management of the combat casualty. Tourniquets have saved countless lives. The novel concept of damage control resuscitation was born on these battlefields and has reduced the mortality rate of casualties requiring massive transfusion from 40% to less than 20%. The Joint Theater Trauma System (JTTS) was implemented to enhance injury care performance and to improve provider communication and dissemination of lessons learned across the vast continuum of care. Efforts of the trauma system have lead to the development of more than 30 evidence-based battlefield relevant clinical practice guidelines, and decreased morbidity and mortality from combat injury. The legacy of this conflict will not only be what we have learned, but also how rapidly we were able to disseminate, educate, and change practice on the battlefield in nearly real-time, and to translate many combat lessons learned into trauma care in the civilian environment. This text is a natural complement of our efforts contributing to evolution of casualty care on the battlefield. Brian Eastridge, MD, FACS Colonel, MC, US Army Trauma Consultant, US Army Surgeon General San Antonio, TX June 2011 Weapons Prologue Effects xiii

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