Assist. Prof. Dr. Hikmet KELEŞ Faculty: Afyon Kocatepe University, Faculty of Veterinary Medicine, Department of Pathology Birth date: 03 February 1972 Foreign language: English Address: Afyon Kocatepe University, Faculty of Veterinary Medicine, Department of Pathology, 03200, ANS Campus, Afyonkarahisar Tel: +90 272 2281312-153 EDUCATION: Faculty (M.Sc.): Istanbul University, Faculty of Veterinary Medicine (1991-1996) Master of Science Thesis: Pathological studies on inflammatory changes of testes and epididymides from bulls slaughtered in the region of Van. Yuzuncu Yil University, Graduate School of Health Sciences, Department of Pathology, Van, Turkey. 2002. (in Turkish, with English abstract). PhD Thesis: Pathological and immunohistochemical techniques for detection of Marek s Disesase in the chicken. Ankara University, Graduate School of Health Sciences. Ankara, Turkey. 2007. (in Turkish, with English abstract). AWARDS: IV. National Veterinary Biochemistry and Clinical Biochemistry Congress, 2-4 July 2009, Istanbul. Poster Award. XI. National Veterinary Surgery Congress, 26-28 June 2008, KuĢadası. Poster Award. 40th Voorjaarsdagen European Veterinary Conference, 26-30 April 2007. Amsterdam, Netherland. Golden Sticker Award by Boehringer Ingelheim. RESEARCH INTEREST: Animal tumours and experimental tumour models Wound healing Oxidative stress Toxic Pathology
UNDERGRADUATE LECTURES: General Pathology Animal Oncology GRADUATE AND POSTGRADUATE LECTURE: Pathology of Laboratory Animals Disease Pathology of Muscle Disease JOB/ACADEMİCAL CAREER: Assist. Prof. Dr., Afyon Kocatepe Univ., Faculty of Veterinary Medicine, 2009- Dr., Afyon Kocatepe Univ., Faculty of Veterinary Medicine, 2007-2009. MSc, Ankara Univ., Graduate School of Health Sciences, 2002-2007. Research Assistant, Yuzuncu Yil Univ., Graduate School of Health Sciences, 1999-2002. Reserve Officer (Food hygienist), 1997-1998 Veterinarian, 1996-1997 MEMBERSHIPS: - The European Association for Cancer Research (EACR), 2009- - Moleküler Kanser AraĢtırma Derneği -MOKAD (Molecular Cancer Research Association), 2009- - Veteriner Patoloji Derneği (Veterinary Pathology Association), 2002- - Ġstanbul Veteriner Hekimler Odası (Istanbul Veterinary Association), 1996- PUBLICATION A- Articles Articles reviewed by SCI, SSCI and AHCI index 1. PESIN, I., KOCA, U., KELES, H., KUPELI-AKKOL, E. (2009). Wound Healing Activity of Rubus sanctus schreber (Rosaceae): Preclinical Study in Animal Models. ecam. September 15, 2009; doi:10.1093/ecam/nep137. 2. YUKSEL, H., KARADAS, E., KELES, H. and DEMIREL, HH. (2009). The Effects of Hexachlorocyclohexane (HCH- γ-isomer, Lindane) Toxication on the Proliferative Activity and Apoptosis in Rat Testes. Acta Veterinaria BRNO. 78:615-620. 3. KELES, H., FIDAN, A.F, CIGERCI, I.H., KUCUKKURT, I., KARADAS, E., DUNDAR, Y. (2009). Increased DNA Damage and Oxidative Stress in Chickens with Natural Marek's Disease. Vet Immunol Immunopathol. 133(1):51-58. 4. KOCA, U., SÜNTAR, I.P., KELES, H., YESĠLADA, E., AKKOL, E.K. (2009). In Vivo Anti- Inflammatory and Wound Healing Activities of Centaurea iberica Trev. ex spreng. J Ethnopharmacol., 126(3): 551-556. 5. AKKOL, E.K., AVCI, G., KUCUKKURT, I., KELES, H., TAMER, U., INCE, S., YESĠLADA, E. (2009). Cholesterol-reducer, Antioxidant and Liver Protective Effects of Thymbra spicata L. var. spicata. J Ethnopharmacol., 126(2): 314-319. 6. OZKUL, I.A., SEPICI-DINCEL, A., KELES, H., VURAL, S.A. (2008). Immunohistochemistry of Bovine Urinary Bladder Mucosal Hyperplasia and Neoplasia. Bull Vet Inst Pulawy, 52:643-647 7. FIDAN, A.F., CIGERCI, I.H., BAYSU-SOZBILIR, N., KUCUKKURT, I., YUKSEL, H., KELES, H. (2008). The Effects of the Dose-dependent (n-hexachlorocyclohexane (Lindane) on Blood and Tissue
Antioxidant Defense Systems, Lipid Peroxidation and Histopathological Changes in Rats. J Anim Vet Adv., 7: 1480-1488. 8. VURAL, S.A., KAPAKIN, K.A.T., KELES, H., OZKUL, I.A. (2007). Adverse Effects of Salmonella enterica serovar enteritidis Vaccine in Chickens. Bull Vet Inst Pulawy, 51:497-501. 9. ÖZYILDIZ, Z., KELEŞ, H., ALÇIĞIR, M.E., AYDIN, Y. (2007). Sertoli Cell Tumor Metastazis in Skin and Visceral Organs of a Dog. Kafkas Üniv Vet Fak Derg., 13: 87-91. (article in Turkish with English abstract) 10. VURAL, S.A., KELEŞ, H., ÖZSOY, ġ., ÖZKUL, Ġ.A. (2007). Oropharyngeal tumors between 1977 to 2005 at dog and cats: a retrospective study. Ankara Üniv Vet Fak Derg., 54:197-203. (article in Turkish with English abstract) 11. VURAL, S.A., HALIGUR, M., BESALTI, O., KELES, H., BILGIHAN, S.E. (2006). Ocular Squamous Cell Carcinoma In a Cow. Indian Vet J., 83:331-332. 12. VURAL, S.A., SAGLAM, M., KELES, H., BOZKURT, MF. (2006). Magenadenokarzinom bei einem Hund. (Gastric adenocarcinoma in a dog). Kleintierpraxis, 51:326-330. 13. VURAL, S.A., KUTSAL, O., KELES, H., HALIGUR, M. (2005). Metastasierendes Rhabdomyosarkom bei einem Hund. (Metastatic Rhabdomyosarcoma in a Dog). Kleinterpraxis, 50:45-50. 14. YENER, Z., SAGLAM, Y.S., TEMUR, A., KELES, H. (2004). Immunohistochemical Detection of Peste des petits ruminants Viral Antigens in Tissues from Cases of Naturally Occurring Pneumonia in Goats. Small Ruminant Res., 51:273-277. 15. YENER, Z., KELES, H. (2001). Immunoperoxidase and Histopathological Studies on Leptospiral Nephritis in Cattle. J. Vet. Med. A, 48: 441-447. Articles reviewed by the other index 1. KELES, I., DEDE, S., KELES, H., DEGER, Y., ALTUG, N. (2000). Studies on Some Antioxidant Vitamin Concentrations in Lambs with Stiff-Lamb Disease. Y.Y.Ü. Vet Fak Derg., 11:79-82. 2. VURAL, S.A., KELES, H., HALIGUR, M. (2005). Unilocular Splenic Hydatidosis In A Sheep. ISSN 1937-8165. The Internet Journal of Veterinary Medicine. Volume 2 Number 1. http://www.ispub.com/ostia/index.php?xmlfilepath=journals/ijvm/vol2n1/cyst.xml. Articles in the peer reviewed journal 1. VURAL, S.A., SAGLAM, M., HALIGUR, M., KELES, H. (2005). Rhabdomyosarcoma in a Dog: Clinical and Pathological Findings. Vet On-Line -The International Journal of Veterinary Medicine ISSN 1360-1962. http://www.priory.com/vet/rhabdomyosarcoma.htm. B- Proceedings International proceedings 1. PESIN, I., KOCA, U., YESILADA, E., KELES, H., KUPELI AKKOL, E. (2009). Wound healing and anti-inflammatory activities of Centaurea iberica Trev. ex Spreng. by in vivo models. 8th International Symposium on the Chemistry of Natural Compounds (8th SCNC). 15-17 June 2009 EskiĢehir, Turkey, (Oral 2. KUTSAL, O., KELES, H., YUMUSAK, N. and SAGLAM, M. (2007). A case of Multiple Tumours in a Dog. International Science Conference, 07-08 June 2007, Stara Zagora, Bulgaria. (Poster 3. KELES, H., VURAL, S.A., SENEL, O.O. and BESALTI, O. (2007). Choroid plexus carcinoma in a horse. 40th Voorjaarsdagen European Veterinary Conference, 26-30 April 2007. Netherland- Amsterdam. (Poster 4. ERGIN, I., VURAL, S.A., SIRIN, Y.S., PEKCAN, Z., KELES, H. and BESALTI, O. (2007). Perinanal neoplasia in Dogs: 33 cases. 40th Voorjaarsdagen European Veterinary Conference, 26-30 April 2007. Netherland -Amsterdam. (Oral 5. VURAL, S.A., SAGLAM, M., HALIGUR, M. and KELES, H. (2006). Rhabdomyosarcoma in A Dog: Clinical and Pathological Findings. International Science Conference, 01-02 June, Stara Zagora, Bulgaria. (Poster 6. VURAL, S.A., KAPAKIN, K., KELES, H. and OZKUL, I.A. (2006). Adverse Effect of Salmonella Enterica Serotype Enteritidis Vaccine in Chickens, International Science Conference, 01-02 June, Stara Zagora, Bulgaria. (Poster National proceedings 1. KELEŞ, H., FĠDAN, A.F., CĠGERCĠ, Ġ.H., KÜÇÜKKURT, Ġ., KARADAġ, E. ve DÜNDAR, Y. (2009). Increased DNA damage and oxidative stress in chickens with Natural Marek's Disease. IV.
National Veterinary Biochemistry and Clinical Biochemistry Congress, 2-4 July 2009, Ġstanbul, 2. FĠDAN, A.F., CĠGERCĠ, Ġ.H., BAYġU-SÖZBĠLĠR, N., KÜÇÜKKURT, Ġ., YÜKSEL, H. and KELEŞ, H. (2009). The Effects of the Dose-dependent (n-hexachlorocyclohexane (Lindane) on Blood and Tissue Antioxidant Defense Systems, Lipid Peroxidation and Histopathological Changes in Rats. IV. National Veterinary Biochemistry and Clinical Biochemistry Congres, 2-4 July, Ġstanbul, Turkey. (Poster 3. ġġrġn, Y.S., KELEŞ, H., BEġALTI, Ö. (2008). Comparison of ATP-MgCl2 and methylprednisolone in experimentally induced spinal cord trauma. XI. National Veterinary Surgery Congress, 26-28 June, KuĢadası, 4. KELEġ, H., ÖZYILDIZ, Z., ALÇIĞIR, M.E., AYDIN, Y. (2006). Sertoli Cell Tumor Metastazis in Skin and Visceral Organs of a Dog. III. Veterinary Pathology Congress, 06-09 September, Elazığ, 5. ÖZYILDIZ, Z., KELEŞ, H., HANEDAN, B., YARDIMCI, B., AYDIN, Y. (2006). Hemangiosarcoma in a dog. III. Veterinary Pathology Congress, 06-09 September, Elazığ, 6. HALIGÜR, M., VURAL, S.A., KELEŞ, H. (2006). Metastatic granulose cell tumour in a dog. III. Veterinary Pathology Congress, 06-09 September, Elazığ, 7. KARADAġ, E., KELEġ, H., BOZKURT, M.F. (2004). Peritoneal and ovarial tuberculosis in a cow, II. Veterinary Pathology Congress, 06-10 September, Kapadokya-NevĢehir, Turkey. (Poster 8. VURAL, S.A., KUTSAL, O., KELEŞ, H., HALIGÜR, M. (2004). Metastatic myofibrosarcoma in a dog. II. Veterinary Pathology Congress, 06-10 September, Kapadokya-NevĢehir, Turkey. (Poster 9. VURAL, SA., HALIGÜR, M, BEġALTI, Ö., KELEŞ, H., BĠLGĠHAN, SE. (2004). Ocular Squamous Cell Carcinoma In a Cow. II. Veterinary Pathology Congress, 06-10 September, Kapadokya-NevĢehir, 10. VURAL, S.A., SAĞLAM, M., KELES, H., BOZKURT, M.F. (2004). Gastic adenocarcinoma in a dog. II. Veterinary Pathology Congress, 06-10 September, Kapadokya-NevĢehir, Turkey. (Oral 11. KELES, H., GÜL, Y. (2002). Pathological Studies on Inflammatory Changes of Testes and Epididymides from Bulls Slaughtered in the Region of Van. I. Veterinary Pathology Congress, 12-13 September, Konya, D- Translations Book chapter translation 1. VURAL, S.A. and KELEŞ, H. (2007). Pratik Klinik Patoloji. Klinik Pratikte At Hekimliği (Manual of Equine Practice), 2nd Ed., Editor: R.J.Rose and D.R. Hodgson. Translation editors: Sancak, A. and Sağlam, M. pp: 551-572. F- Cited articles (cite number) 1. PESIN, I., KOCA, U., KELES, H., KUPELI-AKKOL, E. (2009). Wound healing activity of Rubus sanctus Schreber (Rosaceae): preclinical study in animal models. ecam. September 15, 2009; doi:10.1093/ecam/nep137. (1 time) 2. YENER, Z., SAGLAM, Y.S., TEMUR, A. and KELES, H. (2004). Immunohistochemical Detection of Peste des petits ruminants Viral Antigens in Tissues from Cases of Naturally Occurring Pneumonia in Goats. Small Ruminant Res., 51:273-277. (3 time) 3. FIDAN, A.F., CIGERCI, I.H., BAYSU-SOZBILIR, N., KUCUKKURT, I., YUKSEL, H. and KELES, H. (2008). The Effects of the Dose-dependent (n-hexachlorocyclohexane (Lindane) on Blood and Tissue Antioxidant Defense Systems, Lipid Peroxidation and Histopathological Changes in Rats. J Anim Vet Adv., 7: 1480-1488. (2 time) 4. YENER, Z. and KELES, H. (2001). Immunoperoxidase and Histopathological Studies on Leptospiral Nephritis in Cattle. J. Vet. Med. A, 48: 441-447. (12 time) 5. KELES, I., DEDE, S., KELES, H., DEGER, Y. and ALTUG, N. (2000). Studies on Some Antioxidant Vitamin Concentrations in Lambs with Stiff-Lamb Disease. Y.Y.Ü. Vet Fak Derg., 11:79-82. (3 time)
Research Project Finished Project 1. YÜKSEL, H., KARADAġ, E., SEVĠMLĠ, A., KELEŞ, H. and DEMĠREL, H.H. The Effects of the Dose-dependent (n-hexachlorocyclohexane (Lindane) on Blood and Tissue Antioxidant Defense Systems, Lipid Peroxidation and Histopathological Changes in Rats. AKÜBAPK, 06.VF.19, 2008. (Researcher) 2. ÖZKUL, Ġ.A., VURAL, S.A., HĠÇYILMAZ, Z., KELEŞ, H. Pathomorphological and Immunohistochemical Studies of Tumors of the Urinary Bladder in Cattle in the Black Sea Region of Turkey. AÜBAP. 2004-0810-067, 2008. (Researcher) 3. KARADAġ, E., KELEŞ, H., Pathological and Immunohistochemical Techniques for Detection of Marek s Disesase in the Chicken. AKÜBAPK, 041.VF.03, 2008. (Researcher) 4. GÜL, Y., KELES, H.: Pathological Studies on Inflammatory Changes of Testes and Epididymides from Bulls Slaughtered in the Region of Van, YYÜAF, 00-VF-040, 2002. (Researcher) 5. YENER, Z., KELES, H.: Immunoperoxidase and Histopathological Studies on Leptospiral Nephritis in Cattle, YYÜAF, 00-VF-018, 2001. (Researcher) Continued Project 1- DEMĠRKAN, Ġ., ERTEKĠN T., PAMUK, ġ., ÖZDEMĠR, M., YÜKSEL, H., KELEŞ, H., (2009). Comparison of protective and therapeutic effects of probiotic yogurt and kefir on colo-rectal cancer in mice, TOVAG, 109O306. (Researcher) 2- KELEġ, H., ÖZKUL, Ġ.A., KARADAġ, E. and DEMĠREL, H.H. (2008). Investigation Of The Role Of Nitric Oxide (NO) With Immunohistochemical Techniques In Bovine Enzootic Haematuria-Associated Urinary Bladder Tumors. AKÜBAPK, 08.VF.15. (Head of project) 3- ÇĠÇEK, H., ÇĠÇEK, H., KELEŞ, H., TANDOĞAN, M. and ESER, M. (2008). A study on the coccidiosis-associated economical lost in the commercial egg production. AKÜBAPK, 08.VF.10. (Researcher) 4- TÜLÜCE., Y., KELEŞ, H. (2007). Studies on the serum antioxidant and lipid peroxidation of chicken with Marek s Disease, HÜBAK, 757. (Researcher)