Introduction LABORATORY ANIMAL SCIENCE MODULE 1 IN FELASA C COURSE / MEDVET1
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1 LABORATORY ANIMAL SCIENCE MODULE 1 IN FELASA C COURSE / MEDVET1 JANUAR ! Aurora Brønstad, Chief veterinarian, The Animal Facilities of, University of Bergen Introduction Practical information about the course Definition of laboratory animal science Use of animal in Science in Norway Lab animals and ethics Lab animals and media AIM 1!
2 Practical information Dyreavdelingenes web site Information to participant on Compendium: You do not need it for the first module 1 You need it for the exam in march MEDVET 1 (master students): Exam after the course FELASA-C/B Exam in march Pract inf. cont. FELASA C course Lectures march 2009 Exam (Written exam) hjemme eksamen finished end of the course Practical part: 3 days within March !
3 WHY DO YOU HAVE TO TAKE THIS COURSE??? 13 Planning and conducting an experiment. Persons who conduct or plan experiments must have received a form of training approved by the Mattilsynet (Regulation on Animal Experimentation)! Compulsory training The approved competent person ( ansvarshavende ) is responsible for ensuring that all personnel have the necessary training. 3!
4 FELASA categories A Animal care personnel* B Research technicians C Researchers/scientists D Laboratory animal specialists* *profesionals: life-long learning program Compulsory education - researchers FELASA C Theoretical part: 5 days/35 hours Practical training: 3 days/ 21 hours Self study and exam: 24 hours MEDVET1 Covers 12 of 35 hours theoretical part FEDERATION OF EUROPEAN LABORATORY ANIMAL SCIENCE ASSOCIATIONS! 4!
5 UoB concept based on modules Practical part - 3 days Aimed to be suited to the species Relevant techniques you work with Signed praksisattest by manager/supervisor Start now finalize before exam Can also be obtained at Dyreavdelingene, contact post@viv.uib.no 5!
6 dyreavd/kurs-jan-09.htm Handouts All handouts can be downloaded from 6!
7 Lunch You can have lunch in the cantina on the hospital or in the BBB building. Laboratory animal science Definition: Multidisciplinary branch of science, contributing to the humane use of animals in biomedical research and to the collection of informative unbiased and reproducible data. (Principles of laboratory animal science, L.F.M. van Zutphen, 2001) 7!
8 Laboratory animal science (LAS) Includes: Laws, regulations and laboratory animal ethics. Characteristics of animals: anatomy, physiology, genetics and biochemistry. Influence of environmental factors on experimental results. Laboratory animal procedures and research design. The three R s Reduction Refinement Replacement (Russel & Burch, 1959) Implemented in! planning &! performing! experiments! using animals! 8!
9 Russel & Burch the greatest scientific achievements have alway been the most humane and the most aesthetically attractive, conveying that sense of beauty and elegance which is the essence of science at its most successful The principal of humane experimental techniques Animals used in Norway Mice and rats fish 9!
10 Animals used in Norway mice & rats pigs fish Animals used at Vivarium mice 299 rats 104 pigs 10!
11 Lab animals (ex fish) Ca i i 2006 Fish Ca 0 i in in 2006 Mice Ca in in 2006 Rats Ca in in !
12 Is it ethical to use animals in research? Is it ethical not to use animals in research? 12!
13 Animal experiments and media Ethical guidelines Shows direction and ethical solutions Humans are personally responsible actors 13!
14 Carrols Corporate Social Responsibility (CRP) - pyramid Ethics vs moral When you have a problem and do not know what to do - then you have an ethical problem If you have a problem and know what you should do, but don't do it, then you have a moral problem 14!
15 Summary 1/2 Knowledge on regulatory demands for education of personnel involved in laboratory animal research (theory part, practical part and exam) Know the different FELASA categories for education of lab animal personnel Practical information where to find handouts and teaching material Summary 2/2 Know the definitions of Laboratory animal science Knowledge of the 3R Knowledge of number of animals used in research in Norway Reflection on Ethical questions Reflection on public relations and media 15!
16 Some milestones using animals 1902 understanding of malaria life cycle 1905 study of mechanism of tuberculosis 1936 understanding of chemical signal transmission in nerved pigeon cow, sheep cat, frog, bird 1943 understanding of the role of Vitamin K rat, mice, dog chicken 1945 understanding of the curative effect of penicillium in infectious disease mice 1954 polio vaccine virus and development of vaccine 1966 tumor inducing virus and hormonal treatment of cancer 1990 organ transplantation techniques monkey, mice rat, rabbit, chicken dog Laboratory animal science Definition: Multidisciplinary branch of science, contributing to the humane use of animals in biomedical research and to the collection of informative unbiased and reproducible data. (Principles of laboratory animal science, L.F.M. van Zutphen, 2001) 16!
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