CURRICULUM VITAE. Michel Kranendonk

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1 CURRICULUM VITAE Michel Kranendonk

2 Personal Details Name Michel Kranendonk Nationality Dutch Place and Date of Birth Wormerveer (Netherlands), October 17 th, 1960 Affiliation: Universidade Nova de Lisboa NOVA Medical School/Faculty of Medical Sciences Department of Genetics Address Edifício CEDOC II, Rua Câmara Pestana nº 6, room Lisbon Portugal Telephone , Ext: (office), Ext: (Lab) Fax Address Academic Qualifications 1999 Ph.D. in Molecular Toxicology, Leiden/Amsterdam Centre for Drug Research, Vrije Universiteit Amsterdam, Amsterdam, Netherlands 1987 M.Sc. in Biochemistry and Pharmacochemistry, Vrije Universiteit Amsterdam, Amsterdam, Netherlands 1987 Teaching Certificate in Chemistry, Vrije Universiteit Amsterdam, Amsterdam, Netherlands 1983 B.Sc. in the areas of Mathematics, Physics and Basic Disciplines in Medicine, Vrije Universiteit Amsterdam, Amsterdam, Netherlands Current and Former Academic Positions Member of the Coordination Board of the Center for Toxicogenomics and Health (ToxOmics), Universidade Nova de Lisboa Integrated Member of the Center for Toxicogenomics and Health (ToxOmics), Universidade Nova de Lisboa Member of the Scientific Council of the NOVA Medical School/Faculty of Principal Investigator (Investigador Principal), NOVA Medical School/Faculty of Senior Researcher (Investigador Auxiliar), NOVA Medical School/Faculty of Integrated Member of the Human Molecular Genetics Research Centre (CIGMH), Universidade Nova de Lisboa 2

3 Funded Research Projects As PI/Coordinator: "Domain Dynamics and Control of Electron flux"; Agency Portuguese Foundation for Science and Technology (Fundação para a Ciência e para Tecnologia; FCT-ANR/MHC-CED/0002/2013); Period: 01/05/ /04/2017 The study of Antley-Bixler Syndrome related mutations of cytochrome P450 oxidoreductase: CYPOR polymorphism and the human cytochrome P450 enzyme complex"; Agency: Portuguese Foundation for Science and Technology (Fundação para a Ciência e para Tecnologia; PTDC/SAU-GMG/71911/2006); Period: 03/01/ /29/2012 As Integrated member: Molecular and Cellular Effects of Human Mutations in Cytochrome P450 Reductase ; Agency: National Institute of General Medical Sciences; Type: 1-R01 (GM ); Period: 04/01/ /31/2018 Bioactivation routes of the anti-hiv drug Nevirapine: identification of reactive metabolites and mutagenic potential; Agency: Portuguese Foundation for Science and Technology (Fundação para a Ciência e para Tecnologia; (PTDC/QUI-QUI/113910/2009); Period: 01/02/ /29/2013 Molecular and Cellular Effects of Human Mutations in Cytochrome P450 Reductase ; Agency: National Institute of General Medical Sciences; Type: 1-R01 (GM ); Period: 04/01/ /31/

4 Teaching and Research - Trainees Supervision Research-Trainee Supervisor of in total 31 students (13 pre-graduation students ( Licenciatura ), 5 post-graduation (MSc) students, one MSc (pre- Bologne) student, 5 MSc (post-bologne) student, 3 PhD students, two short-term PhD training students and 3 post-doc students) Lecturer of the post-graduation (M.Sc.) course Genotoxicology and Toxicogenomics, of the Human Molecular Genetics Research Centre (CIGMH), UNL 2009 Lecturer of the post-graduation (M.Sc.) course Genotoxicology and Toxicogenomics, of the Human Molecular Genetics Research Centre (CIGMH), UNL Lecturer of the course Advanced Genetics, part of the PhD training program of the Faculty of Medical Sciences, UNL Lecturer of the MSc course Biochemistry in Health, UNL Lecturer of the MSc course Oncobiology, University of Algarve Lecturer of the PhD course Human Genetics and Infectious Disease; UNL Editorial Board Memberships and Reviewer of International Scientific Journals Associate Editor Frontiers in Pharmacogenetics and Pharmacogenomics Reviewer - Basic and Clinical Pharmacology and Toxicology - Biochimica et Biophysica Acta - Drug Metabolism and Disposition - Drug Metabolism Letters - Environmental Toxicology and Pharmacology - Food and Chemical Toxicity - International Journal of Cancer - Mutation Research - Open Drug Metabolism Journal - Toxicology in Vitro - Toxicology Letters - Xenobiotica 4

5 Grant Evaluation 2012 Evaluator for the Discovery Grant Program of the Natural Sciences and Engineering Research Council, Canada 2009 Evaluator of the Personal Projects Program, Czech Science Foundation, Czech Republic 5