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An t i b 00% SATISFACTION An t i Epitomics Product List The New Generation of Antibodies - RabMAbs The high affinity of rabbit antibodies combined with the specificity of a monoclonal. Every RabMAb is tested in multiple applications before being released, IHC, ICC, IP and Flow Cytometry. Ideal for use with mouse or rat tissues. RabMAbs combine the advantage of high affinity, attributable to their rabbit origin with high specificity due to their monoclonal nature. The high affinity and low background of RabMAbs makes them ideal affinity reagents for demanding applications such as the detection of antigens in formalin fixed paraffin embedded tissue sections. The availability of the first suitable rabbit fusion partner cell line, created in 1995 by Dr. Katherine Knight (1), enabled the generation of stable rabbit hybridomas. Epitomics further developed this cell line and established a robust system allowing for the creation of rabbit monoclonal antibodies on a larger scale. Using this proprietary rabbit monoclonal antibody (RabMAb) technology, Epitomics has developed a large number of antibodies which perform well in a variety of immunoassays (Fig.1). References 1. Spieker-Polet et al., (1995) PNAS 92, 9348-524. 2. Rossi, S. et al., (2005) Am J Clin Pathol 124, 0. 3. Ramos-Vara (2005) Vet. Pathol. 42, 405-426. Learn More at www.epitomics.com Figure 1. General procedure Epitomics uses for making rabbit monoclonal antibodies. Epitomics Antibody Guarantee - We ve got your back! Quality Antibodies Epitomics is committed to producing quality antibodies utilizing our proprietary rabbit fusion partner technology which produces antibodies with high affinity and specificity. Extensive Product Characterization Every Epitomics antibody is always tested in five different assays (, IHC, ICC/IF, FC, and IP) and in multiple species (Human, Mouse, and Rat). For more information, please visit www.epitomics.com. B e t t e r B e t t e r An t i b o d i e s 100% SATISFACTION GUARANTEE S c i e n c e 100% Satisfaction Guarantee We guarantee every antibody to work as described on the product datasheet. If any product purchased from Epitomics does not perform as indicated please contact us and we ll try and help you to get it working. We ll replace or refund any product that doesn t perform as indicated on our datasheet. B e t t e r B e t t e r An t i b o d i e s 100% SATISFACTION GUARANTEE 100% SATISFACTION GUARANTEE S c i e n c e Epitomics, Better Antibody, Better Science UALITY ASSURANCE Visit www.epitomics.com for new products and promotions

Spring 2010 Contents 4 New Epitomics website Epitomics Online Updated website featuring easy online ordering Ordering Information 4 4 International Distributors 5 Product References 6-7 Latest published articles citing Epitomics products and services 9 Human Akt1 ELISA Kit Rabbit vs. Mouse MAb Product Spotlight: 8 Human Akt1 ELISA Kit 9 Thiophosphate Ester RabMAb 10 BioActive RabMAbs 11 Products Primary Antibodies 12 New RabMAbs Over 1600 antibodies including 200+ new antibodies made using Epitomics RabMAb technology Antibodies # - D 12-26 Antibodies E - K 26-36 Antibodies L - Q 36-47 Antibodies R - Z 47-56 Support Products 57-58 Services 63 Custom Antibodies Kits (ELISA, IHC, Purification) Custom Antibody Services Epitomics is dedicated to providing a superior, highly customized service to fulfill your antibody needs. We can help with any or all stages of your project 59-62 63 Custom Polyclonal Antibody Production Services Custom Monoclonal Antibody Production Services Antigen Design Services Antibody Production and Purification Services Assay Development 3

International Distributors Epitomics Online Relaunched! Discover anything to everything related to Epitomics proprietary technology and latest offerings on our comprehensive web site. Convenient With Epitomics Online you have access to Epitomics products, services, and protocols at your finger tip - 24 hours, 7 days a week. Easy and secure 24 hour online ordering system Easy online access to latest products and services from Epitomics Real-time pricing and availability information Comprehensive Over 1600 Rabbit Monoclonals online with complete product information All recommended protocols available for download on technical support page Each product page provides in-depth product information including protein background information, confirmed assays with images (, IHC, ICC, IP, FC) and species cross-reactivity (Human, Mouse, Rat) information. Recommended protocols and technical support guides are also available on our technical support page. Multiple Online Tools Portals - IHC, Antibody Kits, Custom Antibodies and more Fully interactive pathway maps to popular cellular pathways Find all things RabMAbs at www.epitomics.com Ordering Information Ordering: Please place order by Phone, Fax, E-mail or Web site Phone: 877-772-2622 (Toll Free) or 650-583-6688 Monday through Friday from 9AM to 5PM Pacific Standard Time (excluding holidays). Fax: 650-583-6680 E-mail: orders@epitomics.com On-line: www.epitomics.com When placing your order please be prepared to provide the following information: Purchaser s name and telephone number End user s name and telephone number Shipping address Billing address Purchase order number or credit card (VISA and MASTER CARD only) Catalog number and product description Size and quantity of product desired Please note: A Credit Application may be required to be filled out before PO s can be accepted. Payment Terms We accept payments using VISA and MASTER CARD We also accept purchase orders from credit approved institutions. For More Information on Ordering, Please Visit www.epitomics.com Over 1600 Product pages with comprehensive product information Shipping: Epitomics, Inc. attempts to ship all orders within 24 hours following the order placement. All orders are shipped F.O.B. Burlingame, CA. Shipping and handling charges are prepaid and added to your invoice. Orders are shipped via Federal Express. Handling fees may include fee for dry or blue ice when applicable. At the time of order we will provide shipping and delivery estimates based on the availability of the items. Applicable shipping and handling fees will also be provided at the time of order. Order Cancellations: Orders for catalog products can be cancelled at no charge provided that the notice of cancellation is made before the order is shipped. Cancellations received after the order has shipped may be subject to a 20% return and re-stocking fee. For products that are temperature sensitive, order cancellations may not be available. Returns: To return improper or incomplete products please call our customer service department within 72 hours after receipt of the order to obtain a return authorization. Argentina AntibodyBcn S.L. Tel: (+34) 902 220 246 Email: info@antibodybcn.ar Web: www.antibodybcn.com.ar Australia Australian Biosearch Tel: +61 (0)8 9240 5999 Fax: +61 (0)8 9345 1259 Email: customerservice@austbiosearch.com.au Web: www.aust-biosearch. com.au Austria BIOMOL GMBH Tel: (49)-40-853 260-0 Fax: (49)-40-853 260-22 Email: info@biomol.de Website: www.biomol.de Baltic States BIOMOL GMBH Tel: (49)-40-853 260-0 Fax: (49)-40-853 260-22 Email: info@biomol.de Website: www.biomol.de Belgium Bio-Connect B.V. Tel: +31 (0)26 326 4450 FAX: +31 (0)26 326 4451 Email: info@bio-connect.nl Website: www.bio-connect.nl Brazil Life Sciences - Ltda Tel/Fax: 11-3675-7561 Email: sac@life-sciences.com.br Website: www.life-sciences. com.br Canada CedarLane Laboratories Ltd. Toll Free: 1-800-268-5058 Tel: 289-288-0001 Fax: 289-288-0020 Email: general@cedarlanelabs. com Website: www.cedarlanelabs.com Chile AntibodyBcn S.L. Tel: (+34) 902 220 246 Email: info@antibodybcn.ar Web: www.antibodybcn.com.ar China Hangzhou HuaAn Biotech Co. Ltd Tel: 0571-88062880 Fax: 0571-88062876 Email: sales@huabio.com Website: www.huabio.com NeoBioscience Technology Co., Ltd Tel: 0755-26755892, 8008306982 Fax: 00755-26755877 Email: info@neobioscience.com Web: www.neobioscience.com Czech Republic BIOMOL GMBH Tel: (49)-40-853 260-0 Fax: (49)-40-853 260-22 Email: info@biomol.de Website: www.biomol.de Denmark Nordic BioSite AB Free Phone: 800 10595 Fax: +46 (0)8 756 94 90 Email: info@nordicbiosite.dk Website: www.nordicbiosite.dk Finland Nordic BioSite AB Free Phone: 0800 111333 Fax: +46 (0)8 756 94 90 Email: finland@biosite.se Website: www.nordicbiosite.com France EUROMEDEX Tel: +33 3 88 18 07 27 Fax: +33 3 88 18 07 28 Website: www.euromedex.com Germany BIOMOL GMBH Tel: (49)-40-853 260-0 Fax: (49)-40-853 260-22 Freecall (Germany only): 0800-24 666 51 Freefax (Germany only): 0800-24 666 52 Email: info@biomol.de Website: www.biomol.de Greece Biodynamics S.A. Tel: 0030 210 6449421 Fax: 0030 210 6442266 Email: Biodynamics.S.A@ biodynamics.gr Hungary BIOMOL GMBH Tel: (49)-40-853 260-0 Fax: (49)-40-853 260-22 Email: info@biomol.de Website: www.biomol.de India GUARAV ENTERPRISE Tel: 0562-2883724 Fax: 0562-2881414 Email: girish640@yahoo.co.in GeneX Phone: +91 44 6566 3944 Fax: +91 44 2436 2638 E-mail: info@genexindia.net Website: www.genexindia.net Ireland Insight Biotechnology Ltd Tel: +44 (0) 20 8385 0303 Fax: +44 (0) 20 8385 0302 Email: info@insightbio.com Website: www.insightbio.com Israel Almog Diagnostic Tel: +972 3 9773390 Fax: +972 3 9773391 Email: info@almog.co.il Website: www.almog.co.il Italy DBA Italia s.r.l. Tel: +39 02 26922300 Fax: +39 02 26923535 Email: info@dbaitalia.it Website: www.dbaitalia.it Histoline Phone: +39 0255230061 Fax: +39 0255213764 Email: histoline@histoline.com Website: http://www.histoline.com Japan COSMO BIO Co., Ltd. Tel: +81-3-5632-9605 Fax: +81-3-5632-9914 Email: mail@cosmobio.co.jp Website: www.cosmobio.co.jp Korea Essence Medical, Inc. Tel: +82-31-707-1544 Fax: +82-31-707-1999 Email: info@essencemedical.com Website: www.essencemedical.com Luxembourg Bio-Connect B.V. Tel: +31 (0)26 326 4450 Fax: +31 (0)26 326 4451 Email: info@bio-connect.nl Website: www.bio-connect.nl Malaysia Biomarketing Services Sdn. Bhd. Tel: (+603) 6273 3068 Tel: (+603) 6273 6068 Fax: (+603) 6272 0093 Email: info@biomarketing.com.my Website: www.biomarketing.com.my Mexico Biosistemas Avanzados S.A. de C.V. Tel: +52 (55) 5559_6852 FAX: +52 (55) 5559_6987 Email: biosis@biosis.com.mx Website: www.biosis.com.mx Netherlands Bio-Connect B.V. Tel: +31 (0)26 326 4450 FAX: +31 (0)26 326 4451 Email: info@bio-connect.nl Website: www.bio-connect.nl Norway Nordic BioSite AB Tel: 800 10301 Fax: +46 (0)8 756 94 90 Email: info@biosite.se Website: www.biosite.as New Zealand Australian Biosearch Tel: +61 (0)8 9240 5999 Fax: +61 (0)8 9345 1259 Email: customerservice@austbiosearch.com.au Web: www.aust-biosearch.com.au Poland BIOMOL GMBH Tel: (49)-40-853 260-0 Fax: (49)-40-853 260-22 Email: info@biomol.de Website: www.biomol.de Russia OOO Microtests in bio, med, vet Phone: (7) 495 981 13 51 Fax: (7) 495 969 98 26 Email: info@microtesty.ru Website: http://www.microtesty.ru Singapore BST Scientific Pte Ltd Tel: +65-67772856 Fax: +65-67772372 Email: info@bstsci.com Website: www.bstsci.com Spain ATOM S.A. Tel: 34 93 284 79 04 Fax: 34 93 210 82 55 Website: www.atomsa.com AntibodyBcn S.L. Tel: (+34) 902 220 246 Email: info@antibodybcn.ar Web: www.antibodybcn.com.ar Sweden Nordic BioSite AB Tel: +46 (0)8 54 44 33 40 Fax: +46 (0)8 756 94 90 Email: info@biosite.se Website: www.biosite.se Switzerland LabForce AG Tel: +41 (0)61 795 96 20 Fax: +41 (0)61 795 96 21 Email: info@labforce.ch Website: www.labforce.ch Taiwan Excel BioMedical Inc. Tel: +886-2-3393-3099 Fax: +886-2-3393-3097 Email: amyliumh@gmail.com Website: www.exbio.com.tw; www.excel-biomedical.com Hong Jing Co. Phone: +886 2 32338585 Fax: +886 2 32338686 Email: hongjing6668@yahoo.com.tw Website: www.hongjing.com.tw Thailand Biomed Diagnostics Tel: (66)02-8796026, (66)024460755 Fax: (66)02-8796065 Email: nan@biomedthai.com Website: www.biomedthai.com Turkey BioGen Medical Instruments Trading Co. Ltd Tel: +90 212 588 23 55 Fax: +90 212 633 46 77 Email: biogen@biogen.com.tr Website: www.biogen.com.tr United Kingdom Insight Biotechnology Ltd Tel: +44 (0) 20 8385 0303 Fax: +44 (0) 20 8385 0302 Email: info@insightbio.com Website: www.insightbio.com Stratech Scientific Ltd Phone: +44 (0) 1638 782600 Fax: +44 (0) 1638 782606 Email: info@stratech.co.uk Website: http://www.stratech.co.uk USA Epitomics, Inc. Tel: 650-583-6688 Fax: 650-583-6680 Email: info@epitomics.com Website: www.epitomics.com Other Countries: Please contact Epitomics directly 4 5

Product References Product References Here is a sample of the latest references citing Epitomics Rabbit Monoclonal Antibodies (RabMAbs ). please contact support@epitomics.com or visit www.epitomics.com. For more product references, Antibody Cat# References Applications Antibody Cat# References Applications ABCG1, LCAT 1945-1 The reverse cholesterol transport system as a potential mediator of luteolysis in the primate corpus luteum Randy L Bogan and Jon D Hennebold, Reproduction, Jan 2010; 139: 163-176. Ki-67 2642-1 Molecular mechanism by which pioglitazone preserves pancreatic β-cells in obese diabetic mice: evidence for acute and chronic actions as a PPAR gamma agonist Yukiko Kanda et al., Am J Physiol Endocrinol Metab, Feb 2010; 298: E278 - E286. IHC Actin 1184-1 Akt 1085-1 Alpha-Actinin 1 2279-1 AMPK beta 1604-1 Catenin beta 1247-1 CDX2 2475-1 c-kit 1577-1 C-reactive protein (C-term) 1985-1 Cellular Plasticity of Inflammatory Myeloid Cells in the Peritoneal Foreign Body Response Jane E. Mooney et al., Am. J. Pathol., Jan 2010; 176: 369-380. Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells Saskia M. Brachmann et al., PNAS, Dec 2009; 106: 22299-22304. Alpha Actinin2 cytoskeletal protein is required for the functional membrane localization of a Ca 2+ -activated K + channel (SK2 channel) Ling Lu et al., PNAS, Oct 2009; 106: 18402-18407. AMPK β1 Deletion Reduces Appetite, Preventing Obesity and Hepatic Insulin Resistance Nicolas Dzamko et al., J. Biol. Chem., Jan 2010; 285: 115-122. ALX4 dysfunction disrupts craniofacial and epidermal development Hulya Kayserili et al., Hum. Mol. Genet., Nov 2009; 18: 4357-4366. GATA3 Is Selectively Expressed in the Trophectoderm of Peri-implantation Embryo and Directly Regulates Cdx2 Gene Expression Pratik Home et al., J. Biol. Chem., Oct 2009; 284: 28729-28737 Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma Michael A. Davies et al., Clin. Cancer Res., Dec 2009; 15: 7538-7546. Human C-Reactive Protein Does Not Promote Atherosclerosis in Transgenic Rabbits Tomonari Koike et al., Circulation, Nov 2009; 120: 2088-2094. ICC ICC Affinity Purification Lamin B Receptor Lyn Phospho (py396) MEKK3 1398-1 1645-1 1672-1, 1673-1 Paxillin 1500-1 PKR Phospho (pt446) 1122-1 Raf-1 1560-1 Induction of a Massive Endoplasmic Reticulum and Perinuclear Space Expansion by Expression of Lamin B Receptor Mutants and the Related Sterol Reductases TM7SF2 and DHCR7 Monika Zwerger et al., Mol. Biol. Cell, Jan 2010; 21: 354-368. Activities of SYK and PLC gamma 2 Predict Apoptotic Response of CLL Cells to SRC Tyrosine Kinase Inhibitor Dasatinib Zibo Song et al., Clin. Cancer Res., Jan 2010; 16: 587-599. PB1 Domain Interaction of p62/sequestosome 1 and MEKK3 Regulates NF-B Activation Kazuhiro Nakamura et al., J. Biol. Chem., Jan 2010; 285: 2077-2089. Homocysteine promotes vascular smooth muscle cell migration by induction of the adipokine resistin Changtao Jiang et al., Am J Physiol Cell Physiol, Dec 2009; 297: C1466 - C1476. Mechanisms of Protein Kinase PKR-Mediated Amplification of Beta Interferon Induction by C Protein-Deficient Measles Virus Christopher S. McAllister et al., J. Virol., Jan 2010; 84: 380-386. Acute Insulin Signaling in Pancreatic Beta-Cells Is Mediated by Multiple Raf-1 Dependent Pathways Emilyn U. Alejandro et al., Endocrinology, Jan 2010; 10.1210/en.2009-0678., ICC ICC Cytokeratin 4, 5, 6a, 8 1925-1, 1933-1, 1951-1 Recovery of Multipotent Progenitors from the Peripheral Blood of Patients Requiring ECMO Support Kim Chi T Bui et al., Am. J. Respir. Crit. Care Med., Oct 2009 IHC RSK1 Phospho (ps380) 1468-1 Regulation of Protein Kinase A Activity by p90 Ribosomal S6 Kinase 1 Xianlong Gao and Tarun B. Patel, J. Biol. Chem., Nov 2009; 284: 33070-33078. ELK1 1277-1 Elucidation of the ELK1 target gene network reveals a role in the coordinate regulation of core components of the gene regulation machinery Joanna Boros et al., Genome Res., Nov 2009; 19: 1963-1973. Smad2 1736-1 Bright-Field Microscopy Visualization of Proteins and Protein Complexes by In Situ Proximity Ligation with Peroxidase Detection Agata Zieba et al., Clin. Chem., Jan 2010; 56: 99-110. IHC Ezrin 1729-1 Differential proteome analysis of human gliomas stratified for loss of heterozygosity on chromosomal arms 1p and 19q Michael Grzendowski et al., Neuro Oncology, Jan 2010; 10.1093/neuonc/nop025. VEGFR1 1303-1 Soluble-Flt-1 Gene Therapy Ameliorates Albuminuria, but Accelerates Tubulointerstitial Injury in Diabetic Mice. Tomoki Kosugi et al., Am J Physiol Renal Physiol, Dec 2009; FAK Phospho (py576) Fibronectin 2103-1 1573-1 1574-1 Neutrophil granulocytes promote the migratory activity of MDA-MB-468 human breast carcinoma cells via ICAM-1 Strell C et al., Exp Cell Res. 316(1):138-48, 2010 Differential proteomic characterization between normal peritoneal fluid and diabetic peritoneal dialysate Hsien-Yi Wang et al., Nephrol. Dial. Transplant., Jan 2010; 10.1093/ndt/gfp696. VLA4 2101-1 Well Plate Coupled Microfluidic Devices Designed for Facile Image-Based Cell Adhesion and Transmigration Assays Carolyn G. Conant, Michael A. Schwartz, and Cristian Ionescu-Zanetti J Biomol Screen, Jan 2010; 15: 102-106. ICC GAPDH 2251-1 GSK3 beta 1561-1 A Novel Mouse Model for De novo Melanoma Mayuko Y. Kumasaka et al., Cancer Res., Jan 2010; 70: 24-29. Deregulated GSK3β Sustains Gastrointestinal Cancer Cells Survival by Modulating Human Telomerase Reverse Transcriptase and Telomerase Wei Mai et al., Clin. Cancer Res., Nov 2009; 15: 6810-6819. IHC More Product References online @ www.epitomics.com HIAP-1 1040-1 A Novel Paradigm to Trigger Apoptosis in Chronic Lymphocytic Leukemia Sandra Loeder et al., Cancer Res., Dec 2009; 69: 8977-8986 Histone H3 Acetyl (K56) 2134-1 Systematic in vivo structure-function analysis of p300 in hematopoiesis Erin A. Kimbrel et al., Blood, Nov 2009; 114: 4804-4812. JNK2 2037-1 Identification of a Novel Amino Acid Response Pathway Triggering ATF2 Phosphorylation in Mammals Cédric Chaveroux et al., Mol. Cell. Biol., Dec 2009; 29: 6515-6526. 6 7

Comparison - RabMAb vs. Mouse MAb Advantages of Rabbit Monoclonals Product Spotlight New! Human Akt1 ELISA Kit Rabbit Monoclonal Antibodies (RabMAbs ) provide the combined benefits of superior antigen recognition of the rabbit immune system with the specificity and consistency of a monoclonal antibody, bringing you the highest quality antibody possible. To evaluate the specificity and sensitivity of Epitomics RabMAbs, we compared various diagnostic marker specific RabMAbs with the leading commercially available Mouse Monoclonal counterparts. Both antibodies were tested on the same formalin fixed paraffinembedded tissue sample and under their recommended immunohistochemistry conditions. Specific to Human Akt1 protein. No cross-reactivity to Mouse and Rat Akt1 protein. Simple and Fast ELISA kit utilizing Epitomics RabMAb antibody technology. The results shown below demonstrate that Epitomics RabMAbs have higher sensitivity combined with lower background than the comparable mouse monoclonal antibodies. In conclusion, Epitomics RabMAbs are proving to be exceptional affinity reagents for the detection of key diagnostic and prognostic markers in formalin fixed and paraffin embedded (FFPE) tissue sample. CDX2 RabMAb Mouse MAb View More Antibody Comparisons Online @ Fig 1. ELISA analysis using Human Akt1 ELISA Kit (Cat# 6119-1). A) The amount of protein used for ELISA shown in Western Blot and the relationship between the protein concentration of lysates from MCF7 cells and assay optical density readings. B) The relationship between protein concentration of Jurkat cell lysates with or without treatment of LY-294002 and kit assay optical density readings Antibody Name Catalog # Applications Species CDX2 2475-1, IHC, ICC, FC Human Akt1/PKBa is a Ser/Thr protein kinase whose kinase activity plays a key role in various cellular functions, including apoptosis, glycogen synthesis, and cell growth. Akt1/PKBa is activated by various growth and survival factors. Phosphorylation on Thr308, Ser473 and Tyr474 is required for full activity. Akt1/PKBa inhibits apoptosis by phosphorylating and inactivating several targets, including caspase-9. Akt1/PKBa regulates glycogen synthesis by phosphorylating and inactivating glycogen synthase kinase-3a and b. Three mammalian Akt1/PKBa isoforms have been identified. Paraffin-embedded human colonic carcinoma tissue stained with Epitomics CDX2 RabMAb (Cat# 2475-1) and Vendor A s CDX2 Mouse Monoclonal (both at 1:1000 dilution factor) Cathepsin D RabMAb Mouse MAb Antibody Name Catalog # Applications Species Cathepsin D 2487-1, IHC, ICC. FC. IP Human, Mouse Cathepsin D 2431-1, IHC, ICC Human Cathepsin D (Pro) 2510-1, IHC, ICC Human Fig 2. 5 Steps of Sandwich ELISA assay. Paraffin-embedded human breast ductal infiltrating carcinoma tissue stained with Epitomics Cathespsin D RabMAb (Cat# 2510-1, at 1:500 dilution factor) and Vendor A s Cathespin D Mouse Monoclonal (at 1:50 dilution factor) Her2 This assay employs the sandwich enzyme immunoassay technique that detects human Akt1. Rabbit anti-akt1 monoclonal antibody has been pre-coated onto a microplate. Cell lysate is pipetted into the wells. Following extensive washing, mouse anti-human Akt1 monoclonal antibody reagent is added. Following a wash to remove any unbound antibody reagent, goat anti-mouse IgG-HRP is added to the well. After washing away the unbound goat anti-mouse IgG-HRP, a substrate solution is added to the wells to develop color. The magnitude of the absorbance for this developed color is proportional to the amount of human Akt1 protein. RabMAb Mouse MAb ELISA Kit Catalog # Type Species Reactivity Price New Akt1 (Human Specific) 6119-1 Sandwich ELISA (96 Reactions) Human $450 8 Paraffin-embedded human breast carcinoma tissue stained with Epitomics Her2 RabMAb and Vendor D s Her2 Mouse Monoclonal (both at 1:500 dilution factor). Antibody Name Catalog # Applications Species Her2 2064-1, IHC, FC, IP Human, Mouse Her2 4201-1 IHC Human Her2 (py877) 2265-1, ICC Human Her2 (py1139) 1991-1, FC, IP Human Related Products Antibody Catalog # Applications Species Reactivity Price Akt1 1085-1, IHC, ICC, IP Human, Mouse, Rat $250 Akt1 Phospho (ps473) 2118-1, IHC, ICC Human, Mouse $285 Akt1 Phospho (pt308) 2214-1 Human, Mouse $285 Akt Substrates Ab Sampler Kit 5005-1, IHC, ICC, IP, FC Human, Mouse, Rat $535 For More Information - Visit www.epitomics.com 9

Product Spotlight Product Spotlight Thiophosphate Ester RabMAb (Clone 51-8) BioActive Rabbit Monoclonal Antibodies A Novel Rabbit Monoclonal for the Detection of Kinase Substrates Monoclonal Antibody featured in J. Allen, et al. Nature Methods 2007 paper (6) Epitomics RabMAb technology allows the development of monoclonal antibodies with superior antigen recognition and versatile for various demanding applications. Utilizing these unique benefits, Epitomics has developed high quality rabbit monoclonals for neutralization and/or activation for biological activity studies to various protein targets. Identify known and novel substrates to various kinases Fully validated for neutralization and/or proliferation studies, ELISA, and Detect context independent serine, threonine, and tyrosine phosphorylated proteins High specificity for the target protein, leading to efficient neutralization or activation of biological activities Half maximal inhibitory concentration (IC50) available for each antibody Neutralization Neutralizing a specific target of protein with BioActive antibodies can give valuable insight into protein s biological activities. Additionally, neutralization can be utilized to assist in measuring the biological activity of samples containing several bioactive proteins. Antibody Name Fig 1. Reaction sequence for affinity tagging kinase substrates. Cat # Bioactivites Applications Price GM-CSF (Bioactive) 4404-1 AntibodyReceptor ELISA,, Neutralization $245 New IFN Alpha (Bioactive) 4407-1 AntibodyReceptor ELISA,, Neutralization $245 New IL-1B (Bioactive) 4405-1 AntibodyReceptor ELISA,, Neutralization $245 IL-4 (Bioactive) 4400-1 AntibodyReceptor ELISA,, Neutralization $245 IL-6 (Bioactive) 4403-1 AntibodyReceptor ELISA,, Neutralization $245 IL-6R (Bioactive) 4406-1 AntibodyLigand ELISA,, Neutralization $245 IL-15 (Bioactive) 4401-1 AntibodyReceptor ELISA,, Neutralization $245 New RANKL (Bioactive) 4410-1 AntibodyLigand ELISA,, Neutralization $245 New TNF Alpha (Bioactive) 4405-1 AntibodyReceptor ELISA,, Neutralization $245 New VEGF (Bioactive) 4408-1 AntibodyLigand ELISA,, Neutralization $245 Epitomics Thiophosphate Ester Rabbit Monoclonal Antibody (Cat# 2686-1, Clone 51-8) is designed to be used to detect proteins containing thiophosphate ester site following labeling as described by Allen and Shokat (Nature Methods 2007). Protein phospholyation is the most widespread and studied regulatory signaling mechanism that occurs in both eukaryotic and prokaryotic organisms. This mechanism of adding phosphate (PO4) to a protein by a kinase forms the basis of cell signaling networks, from controlling of various protein properties (e.g. function, structure) and to being involved in all fundamental cellular processes (1, 2, 3). However, the biochemical identification of the substrates of kinase of interest (KOI) has been challenging and limited. This is due to the low abundance of most phosphoproteins, and the low affinity and substoichemistry phosphorylation of kinase-tosubstrate interaction (1, 4). To address this limitation, a bio-orthogonal affinity purification and identification of direct kinase substrates has been introduced (6). First, KOI accepts ATPγS, then it is allowed to thiophosphorylate its direct substrates. Second, the thiophospholyation site on the substrates is alkylated with p-nitrobenzylthiophosphate (PNBM). Finally, a thiophosphate ester specific rabbit monoclonal antibody (clone 51-8) is introduced to identify the tagged substrates (Figure 1). This semi-synthetic epitope tagging provides a new way to identify and isolate the substrates of various kinases (4, 5, 6). New Antibody-Ligand Binding Activation/Proliferation For activation/proliferation, BioActive antibodies can be used to induce biological activities in samples by acting as the inducing agents. References: *Data provided courtesy of Dr. Shokat s lab, UCSF Fig 2. Western Blot analysis using Thiophosphate Ester Specific RabMAb (Cat# 2686-1). In vitro kinase reaction using JNK1 protein (10ng) incubated with c-jun-gst substrate (1ug) using ATPγS followed by alkylation with PNBM (2.5mM). Kinase reaction was carried out for 30 minutes at room temperature. PNBM alkylation (2.5mM) was for 2 hours at room temperature. Reaction products were analyzed by western blot with thiophosphate ester specific RabMAb (Cat# 2686-1) at 1:5000, α-gst antibody confirms equal loading. 10 Toll Free : 1.877.7RABMAB (772.2622) 1. 2. 3. 4. 5. 6. Johnson, S.A. and Hunter, T. Nature Methods 2, 17 25, 2005. Hunter, T. Signaling 2000 and beyond. Cell 100, 113 127, 2000. Cozzon, A.J. Ann. Rev. Microbiol. 42, 97 125, 1988. Cai, D, Article Review, Mol. BioSyst., 3, 516 517, 2007. Allen, J.J. et al. J. Am. Chem. Soc., 127(15), 5288 5289, 2005. Allen, J.J. et al. Nature Methods, 4(6), 511 516, 2007. Antibody Name CD40 (Bioactive) Antibody Name Cat # Type Amount Price ThioEster RabMAb 2686-1 RabMAb 50uL (25-50 Blots) $305 For More Information Visit www.epitomics.com www.epitomics.com info@epitomics.com Antibody-Receptor Binding Cat # Bioactivites Applications Price 4402-1 AntibodyReceptor ELISA, FC, Proliferation $245 Visit www.epitomics.com for more information 11

# 14-3-3 b/a (C-term) 1062-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 # 14-3-3 b/a (N-term) 1058-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 New 14-3-3 e (N-term) 2784-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 on (A) fetal brain, (B) SH-SY5Y, (C) 293T and (D) SW480 cell (left). ICC on HeLa (right). The 14-3-3 epsilon protein (14-3-3E) is one of seven isoforms in the 14-3-3 protein family; a family which consists of acidic 30 kda proteins expressed at high levels in neurons of the central nervous system. It is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Specificity: A synthetic peptide corresponding to residues in human 14-3-3E was used as an immunogen. 4-1BBL 2305-1 RabMAb 100µl, IHC, ICC, IP Human $250 4E-BP1 1557-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 4E-BP1 1578-1 RabMAb 100µl, IHC, FC, IP Human $250 4E-BP1 Phospho (ps65) 2206-1 RabMAb 100µl Human, Mouse $285 4E-BP1 Phospho (pt37) 2411-1 RabMAb 100µl Human, Mouse $285 4E-BP1 Phospho (pt70) 2250-1 RabMAb 100µl, IHC Human $285 4E-BP1/2/3 Phospho (pt45) 2334-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $285 A ABCD1 1861-1 RabPAb 100µl, IHC Mouse $250 A ABCD1 2098-1 RabMAb 100µl Mouse $210 ABCG1 1945-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 ACACB Phospho (ps221) 2666-1 RabMAb 100µl Human $285 ACADM 2758-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 New ACADM 2758-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 New ACAT 1864-1 RabPAb 100µl, IHC, ICC Human, Mouse, Rat $250 ACAT 2312-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 ACAT (C-term) 1912-1 RabMAb 100µl, IHC, ICC, IP Human $250 ACE (Membrane form specific) 2504-1 RabMAb 100µl, FC Human, Mouse $250 Acetyl CoA Carboxylase 1 (ACC1) 1768-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 Acetyl CoA Carboxylase 1 (ACC1) Phospho (ps79) Acetyl CoA Carboxylase 2 (ACC2) Phospho (ps221) 2327-1 RabMAb 100µl, ICC Human $285 2666-1 RabMAb 100µl, IHC, ICC, IP Human $285 ACHR (Beta) 2584-1 RabMAb 100µl, FC Human, Mouse, Rat $250 ACHR (Beta, Extracellular) 2123-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 Actin (Alpha, Smooth Muscle) 1184-1 RabMAb 100µl, IHC, IP, FC Human, Mouse, Rat $250 Actins are highly conserved proteins ubiquitously expressed in all eukaryotic cells. They comprise, along with microtubules, a major component of the cytoskeleton. It is expressed in heart and skeletal striated muscle tissue, and in certain smooth muscle tissues, regulating contractile potentials for these cells. Acyl protein thioesterase 1 2650-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Adducin (Alpha, C-term) 1706-1 RabMAb 100µl, IHC, ICC Human, Mouse $250 Adducin Phospho (Alpha, ps481) 1762-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 Adducin Phospho (Alpha, ps59) 2208-1 RabMAb 100µl, IP Human $285 New ADH6 2702-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 IHC on human liver Mammalian alcohol dehydrogenases (ADHs), including ADH1-ADH6, interact extensively in the oxidation and reduction of alcohols and aldehydes. ADH6 is a class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Specificity: A synthetic peptide corresponding to residues in human ADH6 was used as an immunogen. Adiponectin 2548-1 RabMAb 100µl, ICC Human $250 Adiponectin 2594-1 RabMAb 100µl, IP Human $250 AE1 Phospho (py359) 2478-1 RabMAb 100µl Human $285 AFP (C-term) 1757-1 RabPAb 100µl, IHC Human, Rat $250 AFP (C-term) 1791-1 RabMAb 100µl, IHC, IP Human $250 AFP (N-term) 1758-1 RabPAb 100µl, IHC Human, Rat $250 AFP (N-term) 1816-1 RabMAb 100µl, IP Human $250 AGR2 2533-1 RabMAb 100µl, IHC, ICC Human, Rat $250 AGR2 2574-1 RabMAb 100µl, IHC, ICC, IP, FC Human $250 AIF 1020-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Mouse, Rat $250 Akt1 1080-1 RabMAb 100µl Human, Mouse $210 Akt1 (C-term) 1081-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Mouse, Rat $250 Akt1 (Pan) 1085-1 RabMAb 100µl IHC, ICC, IP Human, Mouse, Rat $250 Akt1 Phospho (ps473) 2118-1 RabMAb 100µl, IHC, ICC Human, Mouse $285 Akt1 Phospho (pt308) 2214-1 RabMAb 100µl Human, Mouse $285 Aldh1A1 2023-1 RabPAb 100µl, IHC, ICC, IP Human $250 Aldh1A1 2052-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Aldh1A1 2293-1 RabMAb 100µl, IHC Human $250 Aldh7A1 2022-1 RabPAb 100µl, IHC, ICC, IP Human, Mouse $250 Aldh7A1 2070-1 RabMAb 100µl, IHC. ICC, IP Human, Mouse $250 Aldh7A1 2300-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 Aldolase B 2483-1 RabMAb 100µl, IP Human, Mouse, Rat $250 Aldolase B 2689-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 Aldolase B is one of three known aldolase isoenzymes, and is found in kidney and small adult intestine where it is associated with aldolases A or C. Aldolase B catalyzes the reversible cleavage of fructose 1-phosphate into dihydroxyacetone phosphate and glyceraldehyde. It is involved in both glycolytic and gluconeogenic pathways, where its quaternary structure is critical for maintaining its full catalytic function. Specificity: A synthetic peptide corresponding to N-terminus of human Alpha-actin 3 was used as an immunogen. IHC on human uterus (left) and human skeletal muscle tissue (right) on (A) fetal liver, (B) fetal kidney cell lysate (left). IHC on human fetal liver (right). Specificity: A synthetic peptide corresponding to residues in human Aldolase B was used as an immunogen. Actin (Beta) 1854-1 RabMAb 100µl, IHC, ICC Human, Rat $250 Alk 4204-1 RabMAb 100µl IHC Human $205 Actin (Pan) 1844-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Mouse, Rat $250 Alk Phospho (py1604) 1891-1 RabMAb 100µl, IHC, IP Human $285 Actopaxin Phospho (ps8) 2607-1 RabMAb 100µl, ICC Human, Mouse, Rat $285 Alpha B Crystallin 2421-1 RabMAb 100µl, IHC, ICC, FC Human $250 Acyl protein thioesterase 1 2648-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 Alpha B Crystallin 2523-1 RabMAb 100µl, IHC, ICC Human, Rat $250 Alpha-1 Catenin 2028-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Alpha-2 Catenin 2046-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $250 12 13

Alpha-Actinin 1 2279-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 Alpha-Actinin 1 2358-1 RabMAb 100µl, ICC, FC, IP Human, Mouse $250 Alpha-Actinin 2 2310-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 Alpha-Actinin 2 2340-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 Alpha-Actinin 3 2316-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 AMACR 2682-1 RabMAb 100µl, IHC, IP Human $250 Apolipoprotein E 1930-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 Apolipoprotein E (N-term) 1981-1 RabMAb 100µl, IHC, FC, IP Human $250 Apolipoprotein F 2636-1 RabMAb 100µl, ICC Human, Mouse $250 New Apolipoprotein J 2709-1 RabMAb 100µl, IHC Human $250 Apolipoprotein M 2675-1 RabMAb 100µl, IHC, FC Human $250 New Aquaporin 5 2768-1 RabMAb 100µl, IHC, ICC Human $250 AMACR 2721-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 Amphiphysin 2084-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Amphiphysin 2367-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 AMPK (Gamma 1, N-term) 1569-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 AMPK (Alpha 1) 1596-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 New AMPK Phospho (Alpha 1, ps487) 2802-1 RabMAb 100µl, ICC, IP Human $285 on (A) fetal lung and (B) SW480 cell lysates (left) IHC on human lung (right) Aquaporin 5 is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. Expression of Aquaporin 5 may have pathophysiological implications attributed to a dysfunctional water regulation by Aquaporin 5 such as endolymphatic hydrops (i.e. in Meniere s disease) or sensorineural hearing loss. Specificity: A synthetic peptide corresponding to residues in human Aquaporin 5 was used as an immunogen. The 5-AMP-activated protein kinase (AMPK), a member of the SNF1 (sucrose nonfermentor) kinase family. AMPK is a heterotrimeric protein comprising α (63 kda), β (38 kda) and γ (38 kda) subunits. The alpha subunit is the catalytic subunit (which requires phosphorylation to be active). AMPK also appears to play a role in protecting cells from stresses that cause ATP depletion by switching off ATPconsuming biosynthetic pathways. Specificity: A phospho specific peptide corresponding to residues surrounding Serine 487 of human AMPK alpha 1 was used as an immunogen. on 293T. Cells were either (A) untreated (B) treated with LP (left). ICC on HeLa (right). AMPK (Beta 1) 1604-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 AMPK Phospho (Beta 1, ps181) 2271-1 RabMAb 100µl, IHC, ICC Human $285 Amyloid Beta A4 Precursor (APP) 1565-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Amyloid Beta A4 Variant 40 (Aβ40) 2238-1 RabMAb 100µl Human $210 Androgen Receptor 1852-1 RabMAb 100µl, FC Human, Mouse, Rat $250 New Angiotensin II Receptor (Type 2) 2818-1 RabMAb 100µl, IP Human, Mouse, Rat $250 Angiotensinogen (Precursor) 2513-1 RabMAb 100µl, FC, IP Human $250 New Annexin V 2792-1 RabMAb 100µl Human $250 AP2 (Gamma) 2384-1 RabMAb 100µl, FC, IP Human $250 AP2 (Gamma) 2390-1 RabMAb 100µl, IHC, ICC, FC Human $250 AP2 (Mu 1) 2386-1 RabMAb 100µl, FC Human, Mouse, Rat $250 AP2S1 2647-1 RabMAb 100µl, ICC, FC, IP Human, Mouse, Rat $250 New Ape1 2851-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 Apaf-1 1038-1 RabMAb 100µl, IHC, ICC Human, Mouse $250 APC 1701-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Apolipoprotein A1 1920-1 RabMAb 100µl, IHC, ICC, IP Human $250 Apolipoprotein AII 2718-1 RabMAb 100µl Human $250 New Apolipoprotein AII 2744-1 RabMAb 100µl, ICC, FC Human $250 Apolipoprotein AII (ApoA-II) is the second most abundant protein of the high density lipoprotein particles, accounting for 20% of protein mass of HDL. The concentration of ApoA-I and ApoA-II is inversely correlated with the frequency of heart disease in human. In studies with mice and humans, ApoA-II levels have been associated with increased susceptibility to atherosclerosis, increased free fatty acid levels, increased body fat, and increased insulin resistance ARF1 1635-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 ARK1 (Beta, C-term) 1516-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Arrestin 1 Phospho (Beta, ps412) 1109-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 Arrestin1 (Beta) 1274-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 ASIP 1694-1 RabMAb 100µl, FC Human $250 ASK1 - See MEKK5 Asparagine Synthetase 1732-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 ATF-1 Phospho (ps63) 2456-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 ATF-2 1242-1 RabMAb 100µl, IHC, ICC, IP Human $250 ATF-2 (C-term) 1489-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 ATF-2 Phospho (pt71) 1268-1 RabMAb 100µl, ICC, IP Human $285 Atg7 2054-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 ATM 1549-1 RabMAb 100µl, IHC, ICC, IP Human $250 ATM Phospho (ps1981) 2152-1 RabMAb 100µl, IHC, ICC, IP Human $285 ATP-citrate lyase Phospho (ps455) 1822-1 RabMAb 100µl, IP Human, Mouse, Rat $285 ATP-citrate lyase Phospho (pt447/ps451) 1914-1 RabMAb 100µl, ICC Human, Mouse, Rat $285 ATP-citrate lyase protein (C-term) 1699-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 Aurora-A (C-term) 1800-1 RabMAb 100µl, IHC, IP Human $250 Aurora-B (N-term) 1788-1 RabMAb 100µl, IHC, ICC, IP Human $250 Aurora-C (N-term) 1805-1 RabMAb 100µl Human $210 B B7-1 1859-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 B B7-2 1858-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 B7-H4 2516-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Bad (N-term) 1541-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Bag-1 1526-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $250 Bag-1 (C-term) 1064-1 RabMAb 100µl IHC, ICC Human, Rat $250 Bag-2 2610-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 on human plasma ICC on HepG2 cells Specificity: A synthetic peptide corresponding to residues in human Apolipoprotein AII (ApoA-II) was used as an immunogen. as an immunogen. Bag-2 2622-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 New Bag-3 2783-1 RabMAb 100µl, IP Human $250 Apolipoprotein CIII 2216-1 RabMAb 100µl, FC, IP Human $250 14 15

Bak 1542-1 RabMAb 100µl, IHC, ICC, FC Human $250 Bax 1063-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 Bcl-2 Family Sampler Kit 5001-1 RabMAb 40µl per Ab, IHC, ICC, IP, FC Human, Mouse, Rat $595 IHC on prostate carcinoma with Bcl-x RabMAb (Left) ICC on human lymphoma with Bad RabMAb (Right) The Bcl-2 family of proteins regulate apoptosis by controlling mitochondrial permeability and release of cytochrome c. Bcl-2 is an anti-apoptotic protein that resides in the outer mitochondrial wall and inhibits release of cytochrome c. Bcl-x is expressed as two isomeric forms, Bcl-xL and BclxS and functions to inhibit apoptosis. Bcl-xL forms heterodimers with various proteins, including Bax, Bak and Bcl-2, Kit Description: A sampler kit containing Rabbit Monoclonal antibodies for 8 proteins of the Bcl-2 family (Bcl-2, Bcl-x, Bim, Bid, Bad, Bak, Bag-1, Mcl-1). Bcl-2 1017-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Mouse $250 Bcl-2 related protein A1 (N-term) 1639-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse $250 Bcl-6 (C-term) 1648-1 RabMAb 100µl, IHC, ICC, IP Human $250 Bcl-10 1680-1 RabMAb 100µl, FC, IP Human $250 Bcl-10 (C-term) 1651-1 RabMAb 100µl, IHC, ICC, IP Human $250 Bcl-x 1018-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Mouse, Rat $250 Bcr (C-term) 1588-1 RabPAb 100µl IHC, ICC, IP Human $250 Bcr (C-term) 1684-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Bcr Phospho (py177) 2357-1 RabMAb 100µl Human $285 Beclin-1 2026-1 RabMAb 100µl, IHC, ICC, IP Human $250 Beta Actin - See Actin (Beta) Beta ARK1 - See ARK1 Beta Arrestin - See Arrestin Beta Catenin - See Catenin Beta Synuclein - See Synuclein Beta Tubulin - See Tubulin Beta-2-Microglobulin 2427-1 RabMAb 100µl, ICC, FC, IP Human, Mouse, Rat $250 Beta-Catenin Like Protein 1 2450-1 RabMAb 100µl, FC Human $250 Beta-Catenin Like Protein 1 2399-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Beta-Dystroglycan 2201-1 RabMAb 100µl Human $210 Beta-Synuclein 1977-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Bmx - See Etk B-Myb Phospho (pt487) 2376-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 ICC on HeLa cell lysate (Left) IHC on human urinary bladder carcinoma (Right) Expression of the B-Myb transcription factor is up regulated during late G1 phase of the cell cycle by an E2F-dependent transcriptional mechanism. B-Myb is specifically phosphorylated during S phase, suggesting that a cyclin-dependent kinase (Cdk) regulates its activity. Data indicate that phosphorylation by cyclin A/Cdk2 is directly involved in enhancing B-Myb transactivation activity and that levels of endogenous cyclin A/Cdk2 activity may contribute to cell line-specific B-Myb function. Specificity: A phospho specific peptide corresponding to residues surrounding threonine 487 of human B-Myb was used as an immunogen. b-myc 1708-1 RabMAb 100µl Mouse, Rat $210 New BNP 2772-1 RabMAb 100µl Human $210 B-Raf 1647-1 RabMAb 100µl, IHC, FC, IP Human, Rat $250 B-Raf Phospho (pt401) 2298-1 RabMAb 100µl, IP Human, Mouse, Rat $285 New BRG1 2791-1 RabMAb 100µl Human $210 New BRG1 2776-1 RabMAb 100µl, IHC, ICC Human $250 Brn-3a 2083-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Btk (C-term) 1599-1 RabMAb 100µl, IP Human $250 Btk Phospho (py223) 2207-1 RabMAb 100µl, IP Human $285 Btk Phospho (py551) 1685-1 RabMAb 100µl, ICC Human $285 C C/EBP (C-term) 1479-1 RabMAb 100µl, ICC, IP Human, Rat $250 C C/EBP (N-term) 1478-1 RabMAb 100µl, FC, IP Mouse, Rat $250 C/EBP alpha (C-term) 1704-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 C/EBP alpha (N-term) 1703-1 RabMAb 100µl, ICC, FC, IP Human, Rat $285 C1q (Subunit A) 2464-1 RabMAb 100µl, IHC, ICC, FC Human $250 C1q (Subunit B) 2500-1 RabMAb 100µl Human $250 New C1q (Subunit B) 2734-1 RabMAb 100µl, IHC, ICC Human $250 The complement component C1 is a protein complex that consists of six subunits of C1q. Each C1q subunit of the complex is known to bind to immune complexes, which often are deposited in basement membrane. C1q is a versatile recognition protein that triggers activation of the classical pathway of complement. A modular organization has been suggested of the globular domain, consistent with the view that A, B, and C chains are functionally autonomous modules and have distinct and differential ligand-binding properties. Bfl1 See Bcl-2 related protein A1 Bid 1008-1 RabMAb 100µl, IHC, ICC, IP, FC Human $250 on human plasma cell lysate (Left) IHC on human kidney (Right) Specificity: A synthetic peptide corresponding to residues in human C1q (subunit B) was used as an immunogen. Bim 1036-1 RabMAb 100µl, IHC, ICC, IP Human $250 BIR3 - See HIAP-1 BLNK 1597-1 RabMAb 100µl, IHC, IP Human, Mouse $250 New BM88 2790-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 on (A) fetal brain, (B) Neuro-2a and (C) SH- SY5Ycell lysates (Left) IHC on human tonsil (Right) BM88 is a neuron-specific protein widely distributed in the nervous system and implicated in cell cycle exit and differentiation of neuronal precursors. It is an integral membrane protein, which appears early during brain development and remains at high levels at the mature statebm88 is crucial for the transition from neuroblasts to mature neurons when reaching high levels. Specificity: A synthetic peptide corresponding to residues in human BM88 was used as an immunogen. C1q (Subunit C) 2493-1 RabMAb 100µl, IHC, ICC Human $250 C1q (Subunit C) 2577-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 New C35 2777-1 RabMAb 100µl Human $210 c-abl 1616-1 RabMAb 100µl, IP Human, Rat $250 CAD protein 1697-1 RabMAb 100µl, IHC, ICC Human $250 CAD protein (N-term) 1709-1 RabMAb 100µl, ICC, FC, IP Human, Mouse, Rat $250 Cadherin 1 - See E-Cadherin Cadherin 2 - See N-Cadherin Cadherin 5 - See VE-Cadherin Calcitonin 4208-1 RabMAb 100µl IHC Human, Mouse, Rat $205 BM88 2767-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Calcium/Calmodulin Kinase IV (CaMKIV) Calcium/Calmodulin Kinase IV (CaMKIV) 2292-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 2321-1 RabMAb 100µl, IHC, FC, IP Human $250 16 17

Caldesmon (CaM) 1089-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Mouse, Rat $250 Caldesmon (CaM) 1739-1 RabMAb 100µl, IHC, ICC, IP Human $250 Caldesmon Phospho (pt730) 2497-1 RabMAb 100µl, IP Human, Mouse, Rat $285 Caldesmon Phospho (pt753) 2394-1 RabMAb 100µl, ICC Human $285 on HeLa cell. Cells were either (A) untreated (B) treated with Calyculin A. Caldesmon stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, caldesmon inhibits the actomyosin ATPase by binding to F-actin. This inhibition is reduced by calcium-calmodulin and is promoted by tropomyosin. Phosphorylation of non-muscle caldesmon has been linked to reduction of caldesmon s binding properties to actin, myosin, and calmodulin. Additionally, caldesmon s inhibition of actomyosin ATPase is reduced with its phosphorylation. Specificity: A synthetic phospho-peptide corresponding to residues surrounding threonine 753 of human Caldesmon was used as immunogen. Caldesmon Phospho (pt753) 2394-1 RabMAb 100µl, ICC Human $285 Caldesmon Phospho (ps759) 2560-1 RabMAb 100µl Human $285 Calmodulin (CaM) (C-term) 1716-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Calnexin 2692-1 RabMAb 100µl, IHC, IP Human $250 Calpactin I Light Chain 2528-1 RabMAb 100µl, IHC, ICC, FC Human $250 Calpactin I Light Chain 2595-1 RabMAb 100µl, IHC, FC, IP Human $250 Calpain 1 (Small subunit) 2596-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Calpain 1 (Small subunit) 2638-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 New Calpain 1 (Large subunit) 2912-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Calpain 2 (Large Subunit) 2345-1 RabMAb 100µl, FC, IP Human $250 Calponin-1 (C-term) 1806-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 New Calreticulin 2809-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Calretinin 2448-1 RabMAb 100µl Human, Mouse, Rat $210 Calretinin 2449-1 RabMAb 100µl, IP Human, Mouse, Rat $250 Calretinin 4205-1 RabMAb 100µl IHC Human, Mouse, Rat $205 Calretinin 2624-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Calretinin is considered as a specific marker of mesothelllal cells; it is the only marker that has the utility in distinguishing between sarcomatoid mesotheliomas and sarcomatoid renal cell carcinomas. It is widely used in the panel of makers for distinguishing mesothlioma from adenocarcinoma. Along with calretinin, the panel includes E-cadherin, CEA, and cytokeratin 5/6. Caspase-3 (Active) 1476-1 RabMAb 100µl, IHC, ICC Human, Mouse $250 IHC on hepatocellular carcinoma Caspase-3 is a member of the apoptosis execution functional group of caspases, and is either partially or totally responsible for the proteolytic cleavage of many key proteins during apoptosis, such as poly (ADP-ribose) polymerase (PARP). Caspase-3 is a cytosolic protein found in cells as an inactive 32 kda proenzyme. It is activated by proteolytic cleavage into two active subunits only when cells undergo apoptosis. Specificity: A synthetic peptide corresponding to residues following Serine 29 of human caspase-3 (N-terminus of p17 subunit) was used as immunogen. This antibody only detects the active form of caspase-3 (p17 subunit) of Jurkat cell lysate using (A & B ) anti-pro-caspase-3 RabMAb (cat #1475-1) (C & D) anti-caspase-3 RabMAb (cat #1476-1). (A & C) Jurkat cell lysate (B & D) Jurkat cell lysate + Camptothecin Caspase-3 (Pro) 1061-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Mouse $250 Caspase-3 (Pro) 1475-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Mouse $250 Caspase-5 1764-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Caspase-6 (C-term) 1180-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse $250 Caspase-6 (Pro) 1927-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Caspase-7 1032-1 RabMAb 100µl, IHC, ICC, IP Human $250 Caspase-7 (Pro) 1033-1 RabMAb 100µl, IHC, ICC Human $250 Caspase-8 1007-1 RabMAb 100µl, FC, IP Human, Rat $250 Caspase-8 (N-term) 1006-1 RabMAb 100µl, IHC, FC, IP Human $250 Caspase-9 (Pro) 1023-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 Caspase-9 (Pro) 1084-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 Caspase-10 (Pro) 1035-1 RabMAb 100µl, IHC, ICC, IP, FC Human $250 Catalase 2024-1 RabPAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Catalase 2058-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Catalase 2363-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 Catenin (Beta) 1247-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 Catenin (Beta) 2337-1 RabMAb 100µl, FC Human, Mouse, Rat $250 Catenin (Alpha-1) 2028-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Catenin (Alpha-2) 2046-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $250 Catenin Phospho (Beta, ps33ps37) 2408-1 RabMAb 100µl, Human $285 Catenin Phospho (Beta, pt41/pt45) 2377-1 RabMAb 100µl, IP Human $285 Cathepsin D (mature) 2431-1 RabMAb 100µl, IHC, ICC Human $250 IHC on human brain (left) and human mesothelioma (right) Specificity: A synthetic peptide corresponding to residues in human Calretinin was used as an immunogen. Cathepsin D (pro and mature) 2487-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 Cathepsin D (pro) 2510-1 RabMAb 100µl, IHC, ICC Human $250 CaMKI 2202-1 RabMAb 100µl, FC, IP Human $250 CaMKI 2331-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 CaMKII 2048-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 New CaMKII 2716-1 RabMAb 100µl, IP Human, Mouse, Rat $250 Casein Kinase II (Alpha Subunit) 2079-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 Casein Kinase II (Beta Subunit) 2072-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Caspase-2 1060-1 RabMAb 100µl, FC Human, Mouse $250 Caspase-2 1552-1 RabMAb 100µl, IP Human $250 Caspase-3 1087-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $250 IHC on hepatocellular carcinoma Cathepsin D is a ubiquitously expressed lysosomal protease that is involved in proteolytic degradation, cell invasion, and apoptosis. It is suspected to play important roles in protein catabolism, antigen processing, degenerative diseases, and breast cancer progression. It is possibly involved in Alzheimer s disease-related neurodegeneration through cleavage of amyloid precursor protein into amyloidogenic components. Specificity: A synthetic peptide corresponding to residues on human Cathepsin D was used as an immunogen. on (A) MCF-7 (B) A431 and (C) SKBR3 cell lysates IHC on human breast ductall infiltrating carcinoma Caveolin-1 Phospho (py14) 2267-1 RabMAb 100µl, ICC, IP Human $285 Caveolin-2 2590-1 RabMAb 100µl, IHC, ICC, IP Human $250 Caveolin-2 Phospho (py27) 2240-1 RabMAb 100µl, IP Human $285 Cbl 1487-1 RabMAb 100µl, IHC, ICC Human, Rat $250 Cbl (C-term) 1486-1 RabMAb 100µl, ICC, FC, IP Human $250 Cbl Phospho (py674) 2469-1 RabMAb 100µl, ICC, FC Human $285 18 19

Cbl Phospho (py700) 2375-1 RabMAb 100µl, FC, IP Human $285 Cbl Phospho (py774) 1160-1 RabMAb 100µl, IHC, ICC, FC, IP Human $285 c-cbl Phospho (py731) 1873-1 RabMAb 100µl, IP Human, Mouse, Rat $285 CCL4 - See MIP-1 CCR2/CKR2 (N-term) 2068-1 RabMAb 100µl IHC, ICC, IP, FC Human, Mouse $250 IHC on human spleen CCR2 is a G protein-coupled, seven-transmembrane domain receptor protein. It has been found to be a monocyte chemoattractant protein 1 (MCP-1)-specific receptor. Activation of the CCR2b isoform by MCP-1 binding has been shown to trigger intracelluluar Ca 2+ flux and activation of the Jak/Stat pathway. A variety of chemokine receptors, including CCR2, can serve as HIV fusion co-factors (4), making elucidating their specific functions important for more fully describing the process of HIV infection. Specificity: A synthetic peptide corresponding to the N-terminal residues of the human C-C chemokine receptor type 2 was used as immunogen. The antibody does not cross-react with other CCR family members. CCR3/CKR3 (C-term) 2031-1 RabMAb 100µl, IHC, ICC Human, Mouse $250 CCR5/CKR5 (C-term) 2164-1 RabMAb 100µl, FC Human, Mouse $250 CCR7/CKR7 2075-1 RabMAb 100µl, FC Human, Mouse, Rat $250 CCR7/CKR7 (N-term) 2059-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 CCR8/CKR8 (C-term) 2076-1 RabMAb 100µl, ICC Human, Mouse $250 CCR8/CKR8 (Loop 2) 2077-1 RabMAb 100µl, ICC, FC, IP Human, Rat $250 CCR9/CKR9 (N-term) 2099-1 RabMAb 100µl, ICC, FC Human, Mouse $250 New CCT-alpha 2815-1 RabMAb 100µl, ICC, FC, IP Human $250 CD1 alpha 2539-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 New CD1 alpha 2874-1 RabMAb 100µl, IHC Human $250 CD2 2681-1 RabMAb 100µl, ICC Human $250 CD3 epsilon 1501-1 RabMAb 100µl IHC, ICC, IP Human $250 CD3 epsilon 1502-1 RabMAb 100µl, ICC Human $250 CD3 epsilon 1774-1 RabMAb 100µl, IHC, IP Human $250 CD3 zeta (C-term) 1713-1 RabMAb 100µl, ICC, FC Human $250 CD3 zeta Phospho (py142) 2280-1 RabMAb 100µl, ICC, IP Human $285 CD3 zeta Phospho (py83) 2317-1 RabMAb 100µl, ICC, IP Human $285 CD5 2537-1 RabMAb 100µl, ICC Human $250 CD5 2541-1 RabMAb 100µl, IHC, ICC, IP Human $250 CD5 4210-1 RabMAb 100µl, IHC Human $205 CD8 4207-1 RabMAb 100µl IHC Human $205 CD8 (C-term) 1872-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 CD8a 2519-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 New CD9 2739-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 CD10 2545-1 RabMAb 100µl, ICC Human $250 CD10 2569-1 RabMAb 100µl, FC Human, Mouse, Rat $250 CD10 2545-1 RabMAb 100µl, ICC Human $250 CD21 2546-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 CD22 1638-1 RabMAb 100µl Human, Mouse, Rat $210 CD22 Phospho (py762) 1778-1 RabMAb 100µl, IP Human $285 CD22 Phospho (py807) 1621-1 RabMAb 100µl Human $285 CD22 Phospho (py822) 1610-1 RabMAb 100µl, FC Human $285 CD22 Phospho (py842) 1620-1 RabMAb 100µl Human $285 CD23 4213-1 RabMAb 100µl IHC, IP Human $205 CD23 2685-1 RabMAb 100µl, IHC, FC Human $250 CD29 - See Integrin Beta 1 CD31 2530-1 RabMAb 100µl, IHC, FC Human $250 CD31 2540-1 RabMAb 100µl, IHC, FC, IP Human $250 CD32 Phospho (py292) 2308-1 RabMAb 100µl, IP Human $285 CD34 2150-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 New CD34 2749-1 RabMAb 100µl, IHC, IP Human $250 CD40 (Bioactive) 4402-1 RabMAb 100µg ELISA, FC, Functional Assays CD40 Ligand - See TRAP cleavage Human $245 CD44 1998-1 RabMAb 100µl, IHC, ICC, FC Human $250 CD45 1577-1 RabMAb 100µl, IP Human $250 CD45 (C-term) 1691-1 RabMAb 100µl, IHC, FC Human $250 CD56 2433-1 RabMAb 100µl, ICC, FC, IP Human $250 ICC on SH-SY5Y cells (Left) IHC on human astrocytoma (Right) The neural cell adhesion molecule (NCAM/CD56) has been shown to mediate homophilic cell-cell adhesion in the neuroendocrine system with interactions among immunoglobulin-like domains. It is a multifunction transmembrane protein involved in synaptic plasticity, neurodevelopment, and neurogenesis. NCAM appears on early embryonic cells and is important in the formation of cell collectives and their boundaries at sites of morphogenesis, Specificity: A synthetic peptide corresponding to residues near the C-terminus of human NCAM/ CD56 was used as an immunogen. CD61 2264-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 CD68 2135-1 RabMAb 100µl Human, Mouse, Rat $210 New CD72 2735-1 RabMAb 100µl, ICC Human $250 CD79a/IGBP1 4209-1 RabMAb 100µl IHC, FC Human $205 CD79a 2630-1 RabMAb 100µl, IHC, FC Human $250 CD80 - See B7-1 CD86 - See B7-2 CD90 2694-1 RabMAb 100µl, IHC, ICC Human, Rat $250 New CD90 2695-1 RabMAb 100µl, IHC, ICC Human $250 CD99 2429-1 RabMAb 100µl, IHC, ICC, IP Human $250 New CD99 2873-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 CD11a 1904-1 RabMAb 100µl, IHC ICC, FC, IP Human $250 CD11b 1936-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 New CD11b 2729-1 RabMAb 100µl, IHC, ICC, FC Human $250 CD14 2641-1 RabMAb 100µl, IHC, ICC, FC Human $250 CD20 (C-term) 1632-1 RabMAb 100µl, IHC, FC, IP Human $250 IHC on human tonsil (Left) IHC on human uterus (Right) Cluster of Differentiation 99 (CD99), also known as MIC2, is a T-cell surface glycoprotein involved in the T-cell adhesion process and spontaneous rosette formation with erythrocytes. It functions in the migration of leukocytes and the transport of ganglioside GM1 and transmembrane proteins (2). CD99 is also implicated in other cellular events such as thymocyte selection, apoptosis of neuronal cells, and T cell activation. Specificity: A synthetic peptide corresponding to the extracellular domains in human CD99 was used as an immunogen. CD146 2505-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 CD117 (C-term) 1522-1 RabMAb 100µl, IHC Human $250 20 21

Cdc2 1053-1 RabMAb 100µl, IP Human $250 Cdc2 1161-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Cdc2 1484-1 RabMAb 100µl, IHC Human $250 Cdc25C 1302-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $250 Cdc25C (C-term) 1490-1 RabMAb 100µl, FC, IP Human $250 Cdc25C Phospho (ps216) 1190-1 RabMAb 100µl, ICC, IP Human $285 Cdc42 Phospho (ps71) 2467-1 RabMAb 100µl, ICC Human $285 Cdc6 Phospho (ps106) 2462-1 RabMAb 100µl Human $285 Cdc6 Phospho (ps54) 2430-1 RabMAb 100µl, ICC Human $285 Cdk2 (C-term) 1134-1 RabMAb 100µl, ICC, IP Human, Mouse $250 Cdk2 Phospho (pt14) 2351-1 RabMAb 100µl, IHC, icc, IP Human $285 Cdk2 Phospho (py15) 2395-1 RabMAb 100µl, IP Human, Mouse $285 Cdk4 2341-1 RabMAb 100µl, FC, IP Human $250 Cdk5 (C-term) 1698-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Cdk5 Phospho (py15) 1947-1 RabMAb 100µl, IHC Human $285 Cdk9 2454-1 RabMAb 100µl, IHC, ICC, IP Human $250 Cdk9 2496-1 RabMAb 100µl, IHC Human $250 CDX2 2475-1 RabMAb 100µl, IHC, ICC, FC Human $250 CENP-A (C-term) 1745-1 RabMAb 100µl, IHC, ICC, FC Human, Rat $250 New CGA 2753-1 RabMAb 100µl, IHC Human $250 c-jun Phospho (ps73) 1107-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $285 c-jun Phospho (pt91) 2592-1 RabMAb 100µl, IP Human, Mouse, Rat $285 c-jun Phospho (pt93) 2591-1 RabMAb 100µl, IP Human, Mouse $285 CK - See Cytokeratin c-kit / CD117 (C-term) 1522-1 RabMAb 100µl, IHC Human $250 CKRB/CKR11 (N-term) 2100-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $250 c-myb 1792-1 RabMAb 100µl, IHC, ICC, IP Human $250 c-myc (N-term) 1472-1 RabMAb 100µl, IHC, ICC, IP Human $250 c-myc Phospho (pt58/ps62) 1203-1 RabMAb 100µl, ICC, IP Human, Mouse $285 COPS3 2602-1 RabMAb 100µl, ICC, FC, IP Human, Mouse, Rat $250 Cortactin 2067-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Cortactin 2306-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 COX2 2169-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 COX2 4212-1 RabMAb 100µl IHC Human, Mouse, Rat $205 CPI-17 (Alpha, N-term) 1585-1 RabMAb 100µl, IHC, IP Human, Rat $250 C-Product - See SHH C-reactive protein (C-term) 1568-1 RabMAb 100µl, IHC, IP Human $250 C-reactive protein (C-term) 1985-1 RabMAb 100µl Human $210 New Creatine Kinase B type 2830-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 New Creatine Kinase B type 2879-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 IHC on human placenta CGA belongs to the glycoprotein hormone alpha chain family that includes the alpha subunit of chronic gonadotropin (CG), lutenizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH). These hormones are central to the complex endocrine system that regulates normal growth, sexual development, and reproductive function. The hormones LH, FSH and TSH are secreted by the anterior pituitary gland, while CG is secreted by the placenta. Specificity: A synthetic peptide corresponding to residues at the C terminus of human CGA was used as an immunogen. Creb 1496-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Creb Phospho (ps133) 1113-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 New c-rel 2793-1 RabMAb 100µl, IP Human $250 Crk 1779-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $250 Crk Phospho (py221) 2132-1 RabMAb 100µl, ICC Human $285 CrkL 1524-1 RabMAb 100µl, IHC, ICC, IP Human $250 New CGB 2785-1 RabMAb 100µl Human $210 Chk1 (C-term) 1740-1 RabMAb 100µl, IHC, ICC, FC Human $250 New Chk1 (C-term) 2865-1 RabMAb 100µl Human $210 Chk1 (N-term) 1250-1 RabMAb 100µl, ICC, IP Human, Mouse $250 Chk1 Phospho (ps280) 2643-1 RabMAb 100µl, IP Human $285 Chk1 Phospho (ps296) 2580-1 RabMAb 100µl, ICC Human $285 Chk2 Phospho (ps33/35) 2297-1 RabMAb 100µl, ICC Human $285 Chk2 Phospho (ps33/35) 2297-1 RabMAb 100µl, ICC Human $285 CrkL 1537-1 RabMAb 100µl, IHC, ICC Human $250 CrkL Phospho (py207) 1888-1 RabMAb 100µl, IP Human, Mouse $285 CUL1 2432-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 CUL1 2436-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 CUL3 2489-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 CUL3 2506-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 New CUL4A 2715-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Chk2 Phospho (pt68) 1126-1 RabMAb 100µl, IHC, ICC, IP Human $285 Chk2 Phospho (pt68) 1538-1 RabMAb 100µl, IP Human $285 Chromogranin A 1809-1 RabMAb 100µl, IHC, IP Human $250 Chromogranin A (C-term) 1782-1 RabPAb 100µl, IHC, ICC Human, Mouse, Rat $250 Chromogranin A (N-term) 1773-1 RabPAb 100µl, IHC, ICC Human, Mouse $250 Chromogranin A (N-term) 2349-1 RabMAb 100µl, IHC, ICC, FC Human, Rat $250 New CITED-1 2712-1 RabMAb 100µl, IP Human $250 c-jun (C-term) 1696-1 RabMAb 100µl, IHC, ICC, IP Human $250 on (A) HeLa, (B) A375 and (C) 293T IHC on human breast carcinoma Cullin proteins assemble a large number of RING E3 ubiquitin ligases and regulate various physiological processes, including regulating replication and transcription, DNA repair and cell cycle progression. Two cullin 4 (CUL4) proteins, CUL4A and CUL4B, have been identified. Cul4A functions as an E3 ligase and participates in the proteolysis of several regulatory proteins through the ubiquitin-proteasome pathway. Cul4A associates with MDM2 and p53. Depletion of Cul4A leads to an accumulation of p53. Moreover, expression of Cul4A increases the decay-rate of p53 and delays the accumulation of p53 in response to DNA damage. Specificity: A synthetic peptide corresponding to residues in human CUL4A was used as an immunogen. c-jun (N-term) 1254-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 CUL4 A/B 2547-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 c-jun Phospho (ps63) 1527-1 RabMAb 100µl, IHC, ICC, IP Human $285 Cyclin A2 1547-1 RabMAb 100µl, ICC, IP Human $250 Cyclin A2 (C-term) 1540-1 RabMAb 100µl, IHC, ICC, IP Human $250 Cyclin B1 (C-term) 1495-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 22 23

Cyclin D1 1677-1 RabMAb 100µl, ICC, IP Human $250 Cyclin D1 2261-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Cyclin D1 4202-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $205 Cyclin D3 1846-1 RabMAb 100µl, ICC, FC Human $250 Cyclin E1 1655-1 RabMAb 100µl, ICC, FC, IP Human $250 Cyclin E2 1775-1 RabMAb 100µl, IHC, ICC, IP Human $250 Cyclin E2 (C-term) 1142-1 RabMAb 100µl, IHC, ICC, FC Human, Rat $250 New Cyclin H 2800-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 New Cystatin B 2821-1 RabMAb 100µl, IHC, FC Human, Rat $250 New Cystatin B 2842-1 RabMAb 100µl, ICC Human $250 Cytochrome C 1896-1 RabMAb 100µl, IHC ICC, IP Human $250 Cytochrome C 2119-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Cytochrome C Oxidase Subunit 2 2575-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Cytokeratin Family ICC on HeLa cell lysate (Left) IHC on human ovarian carcinoma (Right) Cytokeratins (CK) are a family of structurally related proteins that form the intermediate flament cytoskeleton in epithelial cells.. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. There are two types of cytokeratins: the low molecular weight / acidic type I cytokeratins and the high molecular weight / basic or neutral type II cytokeratins. Cytokeratins are usually found in pairs comprising a type I cytokeratin and a type II cytokeratin. Type I CK group is comprised of CK10, CK12, CK 13, CK14, CK16, CK17, CK18, CK19 and CK20. While, type II CK groups consists of CK1, CK2, CK3, CK4, CK5, CK6, CK7, CK8 and CK9. Epitomics has developed a panel of Cytokeratin Rabbit Monoclonals Antibodies with high affnity and specifcity - all validated for IHC on FFPE human tissues. Visit for complete IHC data and protocol using our Cytokeratin specific antibodies! Cytokeratin 4 1932-1 RabPAb 100µl, IHC, ICC Human, Rat $250 Cytokeratin 4 1994-1 RabMAb 100µl, IHC, ICC, IP Human $250 New Cytokeratin 4 2843-1 RabMAb 100µl, IHC, ICC Human, Rat $250 Cytokeratin 5 1933-1 RabPAb 100µl, IHC, ICC Human $250 Cytokeratin 5 2290-1 RabMAb 100µl, IHC, ICC, IP Human $250 Cytokeratin 5 (C-term) 1988-1 RabMAb 100µl, IHC, ICC Human $250 Cytokeratin 6 1898-1 RabPAb 100µl, FC Human, Mouse $250 Cytokeratin 15 (C-term) 1954-1 RabMAb 100µl, IHC, ICC, FC Human $250 Cytokeratin 16 2142-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Cytokeratin 17 (C-term) 1960-1 RabMAb 100µl, IHC, ICC, IP Human $250 Cytokeratin 17 (N-term) 1900-1 RabPAb 100µl, IHC, ICC, FC Human, Rat $250 Cytokeratin 18 1433-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Cytokeratin 18 1924-1 RabPAb 100µl, IHC, ICC, FC, IP Human $250 Cytokeratin 19 1887-1 RabPAb 100µl, IHC, ICC, IP Human $250 Cytokeratin 19 2473-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Cytokeratin 19 (C-term) 1968-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Cytokeratin 20 2039-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 D D(1A) dopamine receptor (DRD1) 2192-1 RabMAb 100µl, FC Human, Mouse, Rat $250 D Dab1 2294-1 RabMAb 100µl Mouse, Rat $210 Dab2 2656-1 RabMAb 100µl, FC, IP Human $250 Dab2 2225-1 RabMAb 100µl, ICC, FC, IP Human $250 Dachshund 1 2476-1 RabMAb 100µl, FC, IP Human, Rat $250 DAP-1 1059-1 RabMAb 100µl, IHC, ICC, IP Human $250 DAPK2 (N-term) 2009-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 DAPK3 2034-1 RabMAb 100µl, FC Human $250 DAPK3 2568-1 RabMAb 100µl Human $210 DARPP-32 1710-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 DARPP-32 (C-term) 1711-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 Daxx 1094-1 RabMAb 100µl, IHC, ICC, FC Human $250 Desmin 1466-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 DIABLO - See Smac DJ-1 2391-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 DJ-1 2398-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 DLC8 (N-term) 2003-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 New DLK 2880-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 Cytokeratin 6 1951-1 RabMAb 100µl, IHC, ICC, IP Human $250 Cytokeratin 6 2302-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Cytokeratin 7 2303-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Cytokeratin 7 (C-term) 2181-1 RabMAb 100µl, ICC, FC, IP Human $250 Cytokeratin 7 (N-term) 1899-1 RabPAb 100µl, IHC, ICC, IP Human $250 Cytokeratin 8 1432-1 RabMAb 100µl, IHC, ICC, FC Human $250 Cytokeratin 8 1925-1 RabPAb 100µl, IHC, ICC, IP Human $250 Cytokeratin 8 2032-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 IHC on human placenta on( A) JAR, (B) SH-SY5Y, (C) NCCIT, (D) A549 Delta-like protein (DLK) is a transmembrane protein characterized by six epidermal growth factor (EGF)-like repeat motifs. As a member related to the Notch/Delta/Serrate ligand family of proteins, it inhibits preadipocyte differentiation. DLK may also have a role in cell differentiation processes such as adipogenesis, hematopoiesis, and neuroendocrine differentiation. Specificity: A synthetic peptide corresponding to residues in human DLK was used as an immunogen. Cytokeratin 8 Phospho (ps23) 2147-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $285 New DNMT1 2788-1 RabMAb 100µl, ICC, FC, IP Human $250 Cytokeratin 8 Phospho (ps73) 1431-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $285 DNMT3B 2601-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 Cytokeratin 8 Phospho (ps431) 2193-1 RabMAb 100µl, IHC, ICC, IP Human $285 DNA-PK - See PRKDC Cytokeratin 10 2210-1 RabMAb 100µl, IHC, ICC, IP Human $250 DRAK2 2665-1 RabMAb 100µl, ICC, IP Human $250 New Cytokeratin 13 2713-1 RabMAb 100µl, IHC, ICC Human, Mouse $250 Dsh-3 2093-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 New Cytokeratin 13 2719-1 RabMAb 100µl, IHC, ICC Human $250 Dynamin-1 1869-1 RabMAb 100µl, IP Human $250 Cytokeratin 14 2001-1 RabMAb 100µl, IHC, FC, IP Human $250 Dynamin-1 (C-term) 1851-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 Cytokeratin 15 2557-1 RabMAb 100µl Human $250 Cytokeratin 15 2005-1 RabPAb 100µl, IP Human $250 24 25

Dysferlin 2191-1 RabMAb 100µl, FC Human, Mouse $250 E E-Cadherin 1702-1 RabMAb 100µl, IHC, ICC, IP Human $250 E E-Cadherin Phospho (ps838/840) 2239-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 New ENTPD5 2704-1 RabMAb 100µl Human, Mouse, Rat $250 Endo G (C-term) 2105-1 RabMAb 100µl Human, Mouse, Rat $210 Enolase 2 gamma 2588-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 eef2 1681-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 eef2 (C-term) 1722-1 RabPAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 eef2 (C-term) 2248-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 eef2 Phospho (pt56/58) 1853-1 RabMAb 100µl Human, Mouse, Rat $285 eef-2k 1718-1 RabMAb 100µl, IP Human, Mouse, Rat $250 eef-2k (C-term) 1754-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $250 EGFR 1114-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 EGFR 2116-1 RabMAb 100µl, ICC, FC Human, Mouse $250 IHC on human brain on (A) fetal brain, (B) SH-SY-5Y, (C) HeLa, (D) Y79 Enolase is a glycolytic enzyme that catalyzes the interconversion of 2-phosphoenolpyruvate to phosphoenolpyruvate in the glycolytic pathway. The functional enzyme is a dimer made up of subunits referred to as alpha, beta, and gamma. The alpha-, or nonneuronal, enolase (ENO1) is a nearly ubiquitous form, found in almost all tissues, and its expression precedes that of the other isoforms in the early stage of embryonic development. The beta-, or muscle-specific, enolase (ENO3) is present in adult skeletal muscle, and the gamma-, or neuron-specific, enolase (ENO2) is the major form found in mature neurons and in cells of neuronal origin. Specificity: A synthetic peptide corresponding to residues in human Enolase 2 gamma was used as an immunogen. EGFR (C-term) 2235-1 RabMAb 100µl, ICC, FC, IP Human $250 EGFR (N-term) 1234-1 RabMAb 100µl, FC Human $250 EGFR (Pan) 1902-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 EGFR Family EphA3 1811-1 RabMAb 100µl, IP Human, Mouse, Rat $250 Epithelial Antigen (Ep-CAM) (C-term) 1144-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 EpoR Phospho (py485) 2585-1 RabMAb 100µl, IP Human $250 ICC on A431 with cat# 2116-1 (Left) IHC on human lymph node metastasis with cat# 1902-1 (Right) Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein receptor tyrosine kinase that, activated by epidermal growth factor, affects cell growth and differentiation. Binding of EGF or TGF alpha to EGFR activates tyrosine kinase activity of the receptor. The carboxy terminal tyrosine residues on EGFR, Tyr 1068, Tyr 1148, and Tyr 1173, are the major sites of autophosphorylation, which occurs as a result of EGF binding. EGFR overexpression is exhibited various cancer (e.g. glioma, colorectal carcinoma, breast carcinoma, head and neck carcinoma). The phosphorylation level of EGFR is considered one of the important predicators for outcome in non-small cell lung cancer therapy. Visit to see full list of EGFR family antibodies. EPS15R 1857-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 EPS15R 2388-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 Epsin I 2543-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 ER 4200-1 RabMAb 100µl, IHC, IP Human, Mouse $205 ER (Alpha) 1115-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 ER (Alpha) 2614-1 RabMAb 100µl, IHC Human $250 New ER (Alpha) 2866-1 RabMAb 100µl, IHC, ICC Human $250 EGFR Phospho (pt678) 2344-1 RabMAb 100µl, ICC Human $285 EGFR Phospho (pt693) 2343-1 RabMAb 100µl, ICC, IP Human $285 EGFR Phospho (ps695) 2659-1 RabMAb 100µl, ICC Human $285 EGFR Phospho (py845) 2342-1 RabMAb 100µl, ICC Human $285 ER Phospho (Alpha, ps104/106) 2484-1 RabMAb 100µl, ICC Human $285 ER Phospho (Alpha, ps118) 1091-1 RabMAb 100µl, IHC, ICC Human $285 ER Phospho (Alpha, ps167) 2492-1 RabMAb 100µl Human $285 New ER beta 2780-1 RabMAb 100µl, ICC, IP Human $250 EGFR Phospho (py1068) 1138-1 RabMAb 100µl, IHC, ICC, IP, FC Human $285 EGFR Phospho (ps1070/1071) 2221-1 RabMAb 100µl, ICC, IP Human $285 EGFR Phospho (py1086) 1139-1 RabMAb 100µl, ICC, IP Human, Mouse $285 EGFR Phospho (py1092) 1727-1 RabMAb 100µl, IHC, ICC Human, Mouse $285 EGFR Phospho (py1110) 2284-1 RabMAb 100µl, ICC, IP Human $285 EGFR Phospho (py1173) 1124-1 RabMAb 100µl, IHC, ICC, IP Human $285 eif-2a Phospho (ps51) 1090-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 eif-4b (C-term) 2232-1 RabMAb 100µl, IHC, ICC, FC Human $250 on (A) MCF-7, (B) HeLa cell lysates ICC on HeLa Estrogen Receptor beta (ER beta) is a nuclear hormone receptor which is highly homologous to ER alpha. It functions as a ligand-activated transcription factor, binding to estrogens and activation expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Studies have shown ER beta play a role in modulation of the effects of ER alpha, possibly by inhibiting the transcription activation of ER alpha. ER beta is expressed in many tissues, including human thymus, spleen, ovary and testis. Specificity: A synthetic peptide corresponding to N-terminus of human ER beta was used as an immunogen. eif-4b Phospho (ps504) 2260-1 RabMAb 100µl Human, Mouse, Rat $285 eif-4e 1598-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 ErbB - See HER eif-4e (C-term) 1627-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 ERCC1 2166-1 RabMAb 100µl, FC Human $250 eif-4e Phospho (ps209) 2227-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 New ERG 2805-1 RabMAb 100µl, IHC, ICC Human, Rat $250 eif-5a 1582-1 RabPAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Erk1 (pt202/py204)/erk2 (pt185/ py187) Phospho 1481-1 RabMAb 100µl, IHC, ICC Human $285 eif-5a 1637-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 Erk1/p44 MAPK (C-term) 1171-1 RabMAb 100µl Human,Mouse, Rat $210 eif-5a (N-term) 1634-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 Elk-1 (C-term) 1277-1 RabMAb 100µl, IHC, ICC, IP Human $250 EMSY 1602-1 RabMAb 100µl, ICC, FC, IP Human, Mouse, Rat $250 EMTK/ITK/TSK (C-term) 1581-1 RabPAb 100µl, IHC Human, Mouse, Rat $250 EMTK/ITK/TSK (C-term) 1595-1 RabMAb 100µl, FC, IP Human $250 EMTK/ITK/TSK (N-term) 1625-1 RabMAb 100µl, IHC, FC, IP Human $250 Erk1/p44 MAPK Phospho (pt202/204) 2219-1 RabMAb 100µl, IP Human, Mouse, Rat $285 Erk2/p42 MAPK (C-term) 1586-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Erk3 2030-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 Erk5 (C-term) 1719-1 RabMAb 100µl, ICC, FC, IP Human, Mouse, Rat $250 Estrogen Related Receptor (Alpha) 2131-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 26 27

Etk 1594-1 RabMAb 100µl, IP Human, Mouse, Rat $250 New EYA2 2730-1 RabMAb 100µl, IP Human $250 Ezh 1/2 1940-1 RabMAb 100µl, ICC, FC, IP Human $250 Ezrin 2180-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Ezrin 1729-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Ezrin 2255-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 Ezrin Phospho (py353) 1894-1 RabMAb 100µl, ICC Human $285 F FABP4 New 2757-1 RabMAb 100µl Human, Mouse, Rat $210 F New FABP7 2831-1 RabMAb 100µl, ICC Human $250 Factor VIII Alpha 2559-1 RabMAb 100µl, IHC, IP Human $250 Factor XIII A 2597-1 RabMAb 100µl, IP Human, Rat $250 FADD (N-term) 1825-1 RabMAb 100µl, IHC Human, Mouse $250 New Fibrinogen (Beta chain) 2736-1 RabMAb 100µl, IHC, ICC Human $250 Fibrinogen (Gamma chain) 2693-1 RabMAb 100µl, FC Human $250 New Fibrinogen (Gamma chain) 2743-1 RabMAb 100µl, IHC Human $250 Fibronectin 1573-1 RabMAb 100µl, IHC, IP Human $250 Fibronectin 1574-1 RabMAb 100µl, IHC Human $250 FIH1 2637-1 RabMAb 100µl, FC Human, Mouse, Rat $250 FIH1 2646-1 RabMAb 100µl, IHC, ICC, FC Human $250 Factor inhibiting HIF-1 (FIH1) is an Fe (II)-dependent hydroxylase enzyme that serves as an oxygen sensor in the hypoxia response pathway. FIH1 binds to HIF-1alpha and inhibits its transactivation function. It also binds to VHL, which too functions as a transcriptional corepressor that inhibits HIF-1alpha transactivation function. In addition, FIH1 regulates the Notch signaling output and plays a role in how Notch signaling modulates the hypoxic response. It negatively regulates Notch activity and accelerates myogenic differentiation. FADD Phospho (ps194) 2354-1 RabMAb 100µl, IP Human $285 FAK 1700-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 ICC on HeLa Specificity: A synthetic peptide corresponding to residues in human FIH1 was used as an immunogen. FAK 2146-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 FAK Phospho (py397) 2211-1 RabMAb 100µl Human, Rat $285 FAK Phospho (py576) 2103-1 RabMAb 100µl, FC Human, Mouse, Rat $285 FAK Phospho (py576/577) 2183-1 RabMAb 100µl, ICC, FC, IP Human $285 FAK Phospho (py861) 2153-1 RabMAb 100µl Human, Mouse, Rat $285 FAK2 - See Pyk2 FAK2 (C-term) 1480-1 RabMAb 100µl, IP Human, Rat $250 FAK2 (C-term) 2249-1 RabMAb 100µl, IHC, IP Human, Rat $250 FAK2 (N-term) 1509-1 RabMAb 100µl, IHC, ICC, IP Human,Mouse, Rat $250 Fc gamma RIIb (C-term) 1723-1 RabPAb 100µl, ICC, FC Human $250 Fc gamma RIIb (C-term) 1787-1 RabMAb 100µl, IHC, FC, IP Human, Rat $250 Fc gamma RIIb Phospho (py292) 2308-1 RabMAb 100µl, IP Human $285 New FE65 2660-1 RabMAb 100µl, IHC, ICC Human $250 on (A) Jurkat, (B) 293, (C) A375 Filamin A (C-term) 2242-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Filamin A Phospho (ps1458) 2330-1 RabMAb 100µl, IHC, ICC Human $285 Filamin A Phospho (ps2152) 2285-1 RabMAb 100µl, IHC, ICC Human $285 New FKBP6 2850-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 New FKBP12 2832-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 FKHR 1874-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 Flotillin-1 1678-1 RabMAb 100µl Human. Mouse $210 Flt3-L 1839-1 RabMAb 100µl, IHC. ICC, FC Human $250 Fodrin (Alpha) 2507-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 New Fodrin (Alpha) 2760-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 New Fodrin (Alpha, Cleaved) 2799-1 RabMAb 100µl, IP Human $250 FOXO3a 2071-1 RabMAb 100µl, IHC. ICC Human $250 FRAP - See mtor IHC on human brain Amyloid beta A4 precursor protein-binding family B member 1 (FE65) is a member of a family of multidomain adaptor proteins (FE65, FE65L1, and FE65L2) that form multiprotein complexes with a range of functions. FE65 is highly expressed in the brain and it has three protein-protein interaction domains: a WW domain and two PID/PTB domains. Specificity: A synthetic peptide corresponding to residues in human FE65 was used as an immunogen. FRIH 2443-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 FRIH 2444-1 RabMAb 100µl, IHC Human $250 FYB 2360-1 RabMAb 100µl, IHC, ICC Human, Mouse $250 FYB 2361-1 RabMAb 100µl, IHC, ICC, FC Human $250 Fyn (p59fyn) 1562-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 G Gab1 1626-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 G on SH-SY5Y Gab2 1631-1 RabMAb 100µl, ICC, FC, IP Human, Mouse, Rat $250 Fer 2055-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 GABA(B) R2 2253-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 FES 2720-1 RabMAb 100µl, ICC Human $250 GABA(B) R2 Phospho (ps884) 2320-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $285 Fgr 2517-1 RabMAb 100µl, ICC Human $250 GABA(B) R2 Phospho (ps893) 2311-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 Fgr 2628-1 RabMAb 100µl, IP Human $250 GAD2 2482-1 RabMAb 100µl Human, Mouse, Rat $210 New FGF2 2586-1 RabMAb 100µl, FC, IP Human $250 Galectin-3 2401-1 RabMAb 100µl, IHC, ICC, FC Human $250 FGF Receptor 1 (C-term) 2144-1 RabMAb 100µl Human $210 Galectin-3 2509-1 RabMAb 100µl, IHC, ICC, FC Human, Rat $250 Fibrinogen (Alpha chain) 2688-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $250 Gamma Synuclein (SR) 1978-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Rat $250 New Fibrinogen (Alpha chain) 2761-1 RabMAb 100µl, FC, IP Human $250 GAP43 2256-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 GAP43 (C-term) 1751-1 RabPAb 100µl, IHC, ICC, FC, IP Human, Rat $250 Fibrinogen (Beta chain) 2616-1 RabMAb 100µl, ICC, FC Human, Rat $250 GAP43 (C-term) 2259-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 GAPDH 2251-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 28 29

Gata1 2392-1 RabMAb 100µl, FC Human $250 GCDFP-15 2186-1 RabMAb 100µl, IHC, ICC, FC Human $250 New GCDFP-15 2847-1 RabMAb 100µl, IHC, ICC Human $250 GCN2 Phospho (pt667) 2313-1 RabMAb 100µl, IP Human $285 GCN2 Phospho (pt899) 2425-1 RabMAb 100µl Human $285 Gelsolin 2097-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 Gelsolin 2420-1 RabMAb 100µl, IHC, ICC, IP Human $250 GFAP (C-term) 1665-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $250 GFAP (N-term) 2301-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 GFP (N-term) 1533-1 RabMAb 100µl Human $210 New Glucagon 2752-1 RabMAb 100µl, IHC Human $250 New Glucagon 2810-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 GluR1 1308-1 RabMAb 100µl, IHC, IP Human $250 GluR1 Phospho (ps845) 2491-1 RabMAb 100µl Human, Mouse, Rat $285 GluR2 1828-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 GluR2/3 1905-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 GluR3 1731-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 Glut-4 2203-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 Glycodelin - See PAEP Glycogen Synthase 1741-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Glycogen Synthase (C-term) 1720-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Glycogen Synthase Phospho (ps641) 1919-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $285 GNB2 2515-1 RabMAb 100µl, ICC, FC, IP Human, Mouse, Rat $250 GNB2 2531-1 RabMAb 100µl Human $250 GM130 (Golgi Matrix Protein) 1837-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 GM130 (Golgi Matrix Protein) 2117-1 RabMAb 100µl, FC Human $250 GM-CSF (Bioactive) 4404-1 RabMAb 100µl ELISA,, Inhibit Human $245 Left: Recombinant human GM-CSF stimulates the proliferation of the GM-CSF dependent human TF-1 cells in a dose-dependent manner. Right: Inhibition of TF-1 proliferation by anti-human GM-CSF RabMAb. GM-CSF stimulates the growth and differentiates of hematopoietic precursor cells, such as granulocytic and macrophage cells, eosinophils and erythrocytes. Also, it is involved in stimulating mature end cells and as well as antigen-presenting dendritic cells, therefore, increasing these cells functional capacity to combat against infection. GM-CSF is not required for steady state hematopoiesis state, however, it is essential for maintaining the functional activity of certain macrophages (e.g. immune response specific). Specificity: This antibody was selected for its ability to neutralize human GM-CSF s bioactivity. GOS-28 (Golgi SNARE Protein) 2088-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 GPR49 2495-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 New GPR94 2750-1 RabMAb 100µl Human $210 GRB2 (C-term) 1517-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 GRB2 (N-term) 1584-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 GRK2 (Beta, C-term) 1516-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 GRK5 2338-1 RabMAb 100µl, FC Human $250 GRP1 1643-1 RabMAb 100µl Human, Mouse, Rat $210 GRP1 (C-term) 1759-1 RabPAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 GSK3 (Alpha) 1742-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $250 GSK3 (Alpha, Beta) 2199-1 RabMAb 100µl Human, Mouse, Rat $210 GSK3 (C-term) 1561-1 RabMAb 100µl, IHC, ICC Human, Mouse $250 GSK3 Phospho (Beta, ps9) 2435-1 RabMAb 100µl, IHC, ICC Human $285 GSK3 Phospho (Alpha, Beta, py2169/py279) 2309-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 Gstk1 2050-1 RabMAb 100µl, IHC, ICC, IP Human $250 Gstk1 2583-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 H Hamartin - See TSC1 H HB9/HBLX9 2570-1 RabMAb 100µl, IP Human, Mouse $250 Hck (C-term) 2254-1 RabMAb 100µl, ICC, FC, IP Human $250 Heme Oxygenase 1 (HO-1) 1922-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 Heme Oxygenase 1 (HO-1) 2322-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $250 Hemoglobin alpha chain 2680-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 HER2 / ErbB2 2064-1 RabMAb 100µl, IHC, FC, IP Human $250 HER2 4201-1 RabMAb 100µl IHC Human $205 HER2 Phospho (py877) 2265-1 RabMAb 100µl, ICC Human $285 HER2 Phospho (py877) 2521-1 RabMAb 100µl, IHC, ICC Human $285 HER2 Phospho (py1139) 1991-1 RabMAb 100µl, FC, IP Human $285 HER2 Phospho (pt1221 / T1222) 2626-1 RabMAb 100µl Human $285 HER3 (C-term) 1186-1 RabMAb 100µl, IP Human, Rat $250 HER3 Phospho (py1289) 2526-1 RabMAb 100µl, ICC Human $285 HER4 2218-1 RabMAb 100µl Human, Mouse, Rat $210 HER4 ( C-term) 1200-1 RabMAb 100µl, ICC, FC, IP Human, Mouse $250 New HER4 Phospho (py1056) 2812-1 RabMAb 100µl Human $285 HER4 Phospho (py1162) 2295-1 RabMAb 100µl, IHC, IP Human $285 HER4 Phospho (py1188) 2346-1 RabMAb 100µl, ICC Human $285 HER4 Phospho (py1258) 2371-1 RabMAb 100µl Human $285 Hex 2581-1 RabMAb 100µl, ICC, FC, IP Human $250 HIAP-1 1040-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $250 HIF-1 (Alpha) 2015-1 RabMAb 100µl, IHC, ICC Human, Rat $250 New HIPK2 2748-1 RabMAb 100µl, ICC,FC, IP Human $250 Histones Left: ICC using H3 on HeLa (cat# 1326-1) Middle: ICC using H2B (K5) RabMAb on HeLa (cat# 1763-1) Right: IHC using H2B RabMAb on breast carcinoma (cat# 1847-1) Changes in chromatin structure play a large role in the regulation of transcription in eukaryotes. The nucleosome is the primary building block of chromatin, and is made up of four core histone proteins (H2A, H2B, H3 and H4). Various post-translational modifications, such as acetylation and methylation, of core histones serve as regulators of gene expression. Complete list of Histone related antibodies available at Histone Deacetylase 2 (C-term) 1603-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Histone Deacetylase 3 (C-term) 1580-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Histone Deacetylase 3 (N-term) 2246-1 RabMAb 100µl, IHC, ICC Human, Mouse $250 Histone Deacetylase 4 1576-1 RabMAb 100µl, ICC Human $250 Histone Deacetylase 4 (C-term) 1614-1 RabMAb 100µl, FC, IP Human $250 Histone H2A Acetyl (K5) 1794-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Histone H2A.x Phospho (ps139) 2212-1 RabMAb 100µl, IHC, ICC Human, Rat $285 Histone H2B 1750-1 RabPAb 100µl, IHC, ICC, IP Human, Rat $250 30 31

Histone H2B 1810-1 RabMAb 100µl, IHC, IP Human, Mouse $250 Histone H2B 1847-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Histone H2B Acetyl (K12) 1755-1 RabMAb 100µl, IHC, ICC Human $285 Histone H2B Acetyl (K15) 2170-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 Histone H2B Acetyl (K5) 1763-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 Histone H2B Actyl (K20) 1814-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $285 Histone H2B Type 1B 2402-1 RabMAb 100µl, IHC, ICC Human $250 Histone H3 1326-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Histone H3 Acetyl (K18) 1766-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 Histone H3 Acetyl (K56) 2134-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 Histone H3 Acetyl (K9) 1328-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $285 Histone H3 Acetyl (K14) 1921-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $285 Histone H3 Dimethyl (K4) 1347-1 RabMAb 100µl, IHC, ICC Human, Rat $285 Histone H3 Dimethyl (K9) 1349-1 RabMAb 100µl, ICC Human, Mouse, Rat $285 Histone H3 Phospho (ps10) 1173-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 Histone H3 Phospho (ps28) 1329-1 RabMAb 100µl, IHC, ICC Human, Mouse $285 HSF1 2043-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 HSF1 Phospho (ps303/307) 2108-1 RabMAb 100µl, IHC,ICC Human $285 HSF1 Phospho (ps320) 2446-1 RabMAb 100µl, IHC ICC Human $285 HSF1 Phospho (ps326) 2092-1 RabMAb 100µl, IHC, ICC, IP Human $285 HSF2 2045-1 RabMAb 100µl, ICC, FC Human $250 HSF4 (Isoform A) 2089-1 RabMAb 100µl, IHC, ICC Human $250 HSL Phospho (ps855) 2561-1 RabMAb 100µl Human, Mouse $285 HSP27 2174-1 RabMAb 100µl, IHC, ICC Human $250 HSP27 Phospho (ps15) 2231-1 RabMAb 100µl, IHC, IP Human $285 HSP27 Phospho (ps78) 1543-1 RabMAb 100µl, IHC, ICC, IP Human $285 HSP27 Phospho (ps82) 1118-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $285 HSP60 1724-1 RabPAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 HSP60 1777-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 HSP70 (C-term) 1776-1 RabMAb 100µl, IHC, FC, IP Human $250 HSP73 1966-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 New HSP90 Alpha 2877-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 Histone H3 Phospho (pt3) 2162-1 RabMAb 100µl, IHC, ICC Human $285 Histone H3.3 Phospho (ps28 & 31) 2230-1 RabMAb 100µl Human $285 Histone H3.3 Phospho (ps31) 2657-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 Histone H3T Acetyl (K27) 1767-1 RabMAb 100µl, IHC, ICC Human $285 Histone H4 Acetyl (K5) 1808-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 Histone H4 Acetyl (K8) 1796-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $285 HIV-p24 1523-1 RabMAb 100µl N/A $210 New HLA-Dra 2741-1 RabMAb 100µl, IHC, ICC, IP Human $250 Human class II major histocompatibility complex (MHC) products are essential initiators of cellular immune responses. Their cell surface expression demonstrates aspects of tissue-restriction, inducibility, differentiation-dependence, and coordinate regulation indicative of complex molecular controls mediated primarily at the level of transcription. HLA-DR alpha is a polymorphic cell surface glycoprotein that is crucial for the cellular interaction in immune response. Class II molecules have limited tissue distribution and are predominantly expressed on B lymphocytes and macrophage and present peptides derived from extracellular proteins to T cells IHC on human breast carcinoma on (A) HeLa, (B) Jurkat, (C) SKBR-3, and (D) K562 Heat shock protein 90 alpha (Hsp90 alpha) is a cytosolic homodimeric molecular chaperone that modulates the stability and/or transport of a diverse set of critical cellular regulatory, metabolism, organization, and signaling proteins. Hsp90 distinguishes itself from other chaperones by having most of its known substrates as signal transduction proteins; e.g. non activated steroid hormone receptors, several proto-oncogenic tyrosine and serine/ threonine kinases, and actin. Specificity: A synthetic peptide corresponding to residues in human Hsp90 Alpha was used as an immunogen. HSP90 Beta 1492-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Mouse $250 htert (C-term) 1531-1 RabMAb 100µl, IHC, ICC, FC Human $250 HtrA2 2544-1 RabMAb 100µl, IHC ICC, FC, IP Human, Mouse, Rat $250 IHC on human kidney Specificity: A synthetic peptide corresponding to residues in human HLA-Dra was used as an immunogen. HtrA2 (N-term) 1055-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 Huntingtin Protein (Htt) 1756-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 HLF 2678-1 RabMAb 100µl Human, Mouse, Rat $210 Hmgb1 2639-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 I ICAM-1 1929-1 RabMAb 100µl, IHC, ICC Human $250 I IDO 2121-1 RabMAb 100µl Human $210 Hmgb3 2416-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 IFN alpha R1 (C-term) 1765-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 Hmgb3 2600-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 IFN gamma 1833-1 RabMAb 100µl Human $210 New HNF4 Alpha 2710-1 RabMAb 100µl, ICC Human $250 IGBP1 - See CD79a New HNF4 Alpha 2803-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 hnrnp C1/C2 2438-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 IkappaB alpha 1130-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 IkappaB alpha 2466-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 hnrnp K 1848-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 HNRPUL1 2353-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 HoxB4 2096-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 New IkappaB alpha Phospho (py32) 2798-1 RabMAb 100µl, ICC, IP Human $285 New IkappaB alpha Phospho (py42) 2764-1 RabMAb 100µl, IP Human $285 IKK (Beta) 1601-1 RabMAb 100µl, IHC, FC, IP Human $250 HPK1 (N-term) 1654-1 RabMAb 100µl, IHC, FC Human $250 IKK alpha (N-term) 1615-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 H-Ras (C-term) 1521-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $250 IL-1 (Beta) 1743-1 RabMAb 100µl Human $210 HSD17B1 (C-term) 2002-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 IL-1 (Beta, C-term) 1630-1 RabMAb 100µl Human $210 HSD17B1 (C-term) 2127-1 RabMAb 100µl, IHC, ICC, FC Human $250 IL-1R1 1695-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 IL-2 2645-1 RabMAb 100µl, IHC, ICC Human $250 IL-3R (Beta, C-term) 1850-1 RabMAb 100µl, IHC Human $250 32 33

IL-4 2177-1 RabMAb 100µl, ICC Human $250 IL-4 (Bioactive) 4400-1 RabMAb 100µl ELISA,, Inhibition Study Human $245 IL-6 1457-1 RabMAb 100µl Human $210 IL-6 (Bioactive) 4403-1 RabMAb 100µl ELISA,, Inhibit Human $245 IL-8 1856-1 RabMAb 100µl Human $250 IL-10 1889-1 RabMAb 100µl Human, Mouse, Rat $210 New IL-13 2759-1 RabMAb 100µl, ICC Human $250 New IL-13 2762-1 RabMAb 100µl, ICC Human $250 IL-15 1657-1 RabMAb 100µl Human $210 IL-15 2110-1 RabMAb 100µl Human $210 IL-15 (BioActive) 4401-1 RabMAb 100µl ELISA, Inhibition Study Left: Recombinant human IL-15 stimulates the proliferation of human CTLL-2 cells in a dose-dependent manner Right: Inhibition of CTLL-2 proliferation by anti-human IL-15 RabMAb Human $245 IL-15 regulates T and natural killer cell activation and proliferation, causes B cell proliferation and differentiation and stimulates chemotaxis of T cells. High concentrations of IL-15 have been observed in inflamed joints of rheumatoid arthritis patients, suggesting a role for IL-15 in inflammatory diseases where there is recruitment of leukocytes. Specificity: This antibody was selected for its ability to neutralize human IL-15 bioactivity. The crossreactivity with IL-15 of other species has not been tested. IL-17 1656-1 RabMAb 100µl Human, Mouse $210 IL-18BP 1893-1 RabMAb 100µl, IHC, FC Human, Rat $250 ILF3 2640-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 ILF3 2684-1 RabMAb 100µl, IHC, ICC, IP Human $250 ILK 1883-1 RabPAb 100µl, IP Human, Mouse, Rat $250 ILK 1979-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 ILK 2525-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 Indian Hedgehog (IHH) 1910-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 Inhibin Alpha Chain 2623-1 RabMAb 100µl, FC Human, Mouse, Rat $250 INK4a - See p16 INP4A 2605-1 RabMAb 100µl Human, Mouse, Rat $210 INP4B 2512-1 RabMAb 100µl, FC Human, Mouse, Rat $250 New Insulin 2555-1 RabMAb 100µl, IHC Human $250 Integrin Beta 1 2288-1 RabMAb 100µl, IHC, ICC Human $250 Integrin Beta 1 Phospho (py783) 2172-1 RabMAb 100µl Human $285 Integrin Beta 3 2677-1 RabMAb 100µl, IP Human, Mouse, Rat $250 Integrin beta-3 (CD61 antigen, GP IIIa) is a member of the integrin family of integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta-3 forms a Ca2+-dependent heterodimer complex with the GP IIb chain in platelet. The cytoplasmic domain of Integrin beta-3 has be suggested to have a key role in cell adhesion. Following activation integrin beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surfaces. Specificity: A synthetic peptide corresponding to residues in human Integrin beta-3 was used as an immunogen. (A) THP-1 treated with TPA, (B) HUVEC, (C) human spleen, (D) human plasma Integrin Beta 3A 2264-1 RabMAb 100µl, IHC Human, Mouse, Rat $285 IPP-1 1747-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 IRAK-3 (C-term) 1564-1 RabMAb 100µl, IP Human $250 IRAK-4 (N-term) 1589-1 RabMAb 100µl, ICC Human $250 IRF-3 Phospho (ps386) 2562-1 RabMAb 100µl, ICC Human $285 IRF-3 (N-term) 2324-1 RabMAb 100µl, IHC, FC Human, Mouse $250 IRF-3 (C-term) 2241-1 RabMAb 100µl, IHC, FC, IP Human $250 IRR alpha subunit 1690-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 IRS-1 1692-1 RabMAb 100µl, IHC, ICC, IP Human $250 IRS-1 Phospho (py896) 1813-1 RabMAb 100µl Human, Mouse, Rat $285 IRS-2 1802-1 RabMAb 100µl, IHC, ICC, IP Human $250 IRS-2 (Pan) 1849-1 RabMAb 100µl, IHC, IP Human $250 IRS-4 (C-term) 1958-1 RabMAb 100µl, IHC, FC, IP Human $250 ISG15 2625-1 RabMAb 100µl, ICC Human $250 New ISG15 2724-1 RabMAb 100µl, ICC Human $250 ITAM - See CD11b ITAX (C-term) 1975-1 RabMAb 100µl, IHC, ICC, IP Human $250 ITGB1 - See LFA-1a ITGB2 - See LFA-β2 ITK - See EMTK J JAK2 New 2863-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 J JAK2 Phospho (py1007/1008) 1477-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 New JAK3 (N-term) 2856-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 Insulin is a hormone that regulates glucose homeostasis. It increases cell permeability to monosaccharides, amino acids and fatty acids, and it accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. Insulin is a heterodimer of a B chain and an A chain linked by two disulfide bonds. It is synthesized in the beta cell of the pancreas as the precursor, proinsulin, where the carboxyl terminus of the B-chain is connected to the amino terminus of the A-chain by a C-peptide. JAK3 (C-term) 1785-1 RabMAb 100µl, FC, IP Human $250 JAM1 (N-term) 1840-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 JNK1/JNK2/JNK3 Phospho (py185/ py223) 2155-1 RabMAb 100µl, IP Human, Mouse, Rat $285 IHC on human pancreas Specificity: A synthetic peptide corresponding to residues in human Insulin was used as an immunogen.. New JNK1 2852-1 RabMAb 100µl, IP Human, Mouse, Rat $250 JNK2 2037-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 K KDR - See VEGFR2 K on fetal pancreas lysate Keratin - See Cytokeratin INSR / IGF-R Phospho (py1185) 2182-1 RabMAb 100µl, ICC, IP Human $285 Integrin Alpha Phospho (ps1027) 2499-1 RabMAb 100µl Human, Mouse, Rat $285 Ki-67 4203-1 RabMAb 100µl IHC Human, Mouse, Rat $205 Ki-67 2642-1 RabMAb 100µl IHC, ICC, FC Human $250 Integrin Beta 1 1798-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 34 35

Ki-67 2746-1 RabMAb 100µl, IHC, ICC, FC Human $250 Left: IHC on human tonsil Middle: IHC on human colonic adenocarcinoma Right: ICC on HeLa Ki-67 is expressed in all proliferating cells which are in the active phases of the cell cycle (late G1, S, G2, and mitosis), but absent in resting cells. Due to the fact that Ki-67 can be used to determine the growth fraction (the proportion of the cells committed to the cell cycle), it is consider an important marker in human tumor diagnostics and prognostics Specificity: A synthetic peptide corresponding to residues in human Ki-67 was used as an immunogen. KID 2418-1 RabMAb 100µl, FC, IP Human $250 KID Phospho (ps427) 2442-1 RabMAb 100µl Human $285 Kip1 - See p27 Kip2 2372-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 KSR1 2234-1 RabMAb 100µl, IHC, ICC Human, Mouse $250 KSR1 Phospho (ps404) 2403-1 RabMAb 100µl, ICC Human $285 New Ku70 2829-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Ku80 2579-1 RabMAb 100µl, IHC, ICC, FC Human $250 Ku80 2620-1 RabMAb 100µl, IHC, ICC, IP Human $250 Kv4.2 1834-1 RabMAb 100µl, IHC, FC Human $250 L LAT 1499-1 RabMAb 100µl, IHC, FC, IP Human $250 L LAT Phospho (py191) 1225-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 LAT Phospho (py200) 2274-1 RabMAb 100µl, ICC Human $285 Lyn Phospho (py507) 1659-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $285 New Lysozyme C 2669-1 RabMAb 100µl, ICC, IP Human $250 M MAG 1804-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 M MALT1 (N-term) 1664-1 RabMAb 100µl, FC, IP Human $250 New MAP2 Phospho (ps136) 2547-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $285 MAPILC3A 2122-1 RabMAb 100µl, FC Human, Mouse, Rat $250 MAPILC3A (C-term) 2057-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 MAPILC3A (N-term) 1970-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 MAPKAP Kinase-2 1497-1 RabMAb 100µl, IP Human, Mouse, Rat $250 MAPKAP Kinase-2 Phospho (pt334) 1983-1 RabMAb 100µl, IHC, ICC Human $285 MARCKS 1944-1 RabMAb 100µl, IHC, ICC, FC Human $250 MARCKS Phospho (ps159/s163) 2156-1 RabMAb 100µl, IP Human, Mouse, Rat $285 New MARCO 2898-1 RabMAb 100µl Human $250 MARK3 1952-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 MART-1 (N-term) 1989-1 RabMAb 100µl, IHC Human $250 MBD1 2667-1 RabMAb 100µl, IHC, ICC, IP Human $250 MBP 1982-1 RabMAb 100µl, ICC, FC, IP Human, Mouse, Rat $250 Mcl-1 1239-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 New MCM2 2901-1 RabMAb 100µl Human $250 New MCM2 Phospho (ps27) 2888-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 LCAT 2013-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 LCK 1515-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 LCK Phospho (py505) 2217-1 RabMAb 100µl Human, Mouse $285 LDH-A 1886-1 RabPAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 LDH-A 1980-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 LDH-A (Muscle subunit) 2468-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 LDH-B 1974-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 ICC on HeLa Minichromosome maintenance protein 2 (MCM2) is a member of the MCM family that regulates mammalian DNA replication. This family is composed of six related subunits, called the hexameric MCM2-7 complex, that are conserved in all eukaryotes. It functions as a replicative helicase, the molecular motor that both unwinds duplex DNA and powers fork progression during DNA replication. Ser27, Ser41, and Ser139 are suggested to be Cdc7/Dbf4 phosphorylation sites in MCM2. Specificity: A phospho specific peptide corresponding to residues surrounding serine 27 of human MCM2 was used as an immunogen. LDH-B 2090-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 on HeLa, (A) untreated or (B) treated with AP LDH-C 2065-1 RabMAb 100µl, IHC, FC Human $250 LDH-C (N-term) 2289-1 RabMAb 100µl Human $210 LDL Receptor (C-term) 1956-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 MCM5 2374-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 MCM5 2380-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 MCM7 2025-1 RabPAb 100µl, IP Human, Rat $250 LEF-1 2091-1 RabMAb 100µl, IHC, ICC, FC Human $250 MCM7 2056-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 LEF-1 2458-1 RabMAb 100µl, IHC, ICC Human $250 LFA-1a - See CD11a LFA-beta2 / ITGB2 1890-1 RabMAb 100µl, IP Human $250 LFA-beta2 / ITGB2 Phospho (ps745) 1911-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 LIMK2 (C-term) 1795-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 LIMS1 2364-1 RabMAb 100µl, FC Human, Mouse, Rat $250 New Lipin-1 2789-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 LMO2 2668-1 RabMAb 100µl, FC, IP Human $250 New LRP1 2703-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 LRP6 Phospho (ps1490) 2457-1 RabMAb 100µl, ICC Human $285 LRPAP1 2534-1 RabMAb 100µl, IHC FC Human, Mouse, Rat $250 Lyn 1619-1 RabMAb 100µl, IP Human $250 Lyn Phospho (py396) 1645-1 RabMAb 100µl, FC Human $285 MCM7 2318-1 RabMAb 100µl, ICC, FC Human $250 M-CSF 1876-1 RabMAb 100µl, IHC, ICC, IP Human $250 MEF2A 2080-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 MEK1 (C-term) 1235-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Rat $250 MEK1 (N-term) 1518-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 MEK1 Phospho (pt286) 2336-1 RabMAb 100µl, IP Human $285 MEK1 Phospho (pt292) 2233-1 RabMAb 100µl Human $285 New MEK1 Phospho (ps298) 2711-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 MEK1/MEK2 Phospho (ps218/222) 1470-1 RabMAb 100µl, IHC, ICC, IP Human $285 MEK2 (N-term) 1236-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Rat $250 MEKK2 1662-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 MEKK2 (C-term) 1714-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 MEKK3 (C-term) 1673-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 MEKK3 (N-term) 1672-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 36 37

MEKK4 1693-1 RabMAb 100µl, IHC, ICC, FC Human $250 MEKK5 (N-term) 1772-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse $250 New Menin 2817-1 RabMAb 100µl, IHC, ICC, IP Human $250 New Mesothelin 2834-1 RabMAb 100µl Human $210 MerTK 1633-1 RabMAb 100µl, IHC, FC, IP Human, Mouse $250 Met (N-term) 1996-1 RabMAb 100µl, IHC, ICC Human $250 Met Phospho (py1349) 2319-1 RabMAb 100µl, IHC, ICC, IP Human $285 Met is a receptor protein-tyrosine kinase (RPTK) for hepatocyte growth factor (HGF), which is a multifunctional cytokine controlling cell growth, morphogenesis, and motility. Met overexpression has been identified in a variety of human cancers. Met-mediated invasive growth requires autophosphorylation of the receptor on tyrosines located in the kinase activation loop (Tyr(1234)-Tyr(1235)) and in the tail (Tyr(1349)-Tyr(1356)). Specificity: A phospho specific peptide corresponding to residues surrounding tyrosine 1349 of human Met was used as an immunogen. This antibody detects Met phosphorylated at tyrosine 1349. on A431 cell lysate A) untreated and B) treated with AP mglur5 2237-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 MHC class 1 1913-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 MHC class 1 2307-1 RabMAb 100µl, IHC, ICC, FC Human $250 Midkine (C-term) 1937-1 RabMAb 100µl, IHC, ICC, IP Human $250 MMP-3 1908-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 MMP-8 2145-1 RabMAb 100µl, IHC, ICC Human $250 MMP-9 2551-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $250 MMP-9 1939-1 RabMAb 100µl, IHC, ICC, FC Human $250 MMP-9 (Propeptide) 1995-1 RabMAb 100µl, IHC, FC Human $250 MMP-11 1881-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 MMP-12 (C-term) 1906-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 MMP-13 1923-1 RabMAb 100µl Human, Mouse $210 MMP-14 2010-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 MMP-17 2011-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 MMP-20 1946-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 MMP-21 1955-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 MMP-26 2141-1 RabMAb 100µl, FC Human, Mouse, Rat $250 Mo25 2027-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 New Mo25 2867-1 RabMAb 100µl Human, Mouse, Rat $210 Moesin 2036-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 New MRP8 / S100A8 2732-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 MIP-1 (Beta, C-term) 1737-1 RabMAb 100µl Human $210 MIP-1 (Beta, C-term) 1738-1 RabMAb 100µl Human $210 MKK3 (N-term) 1728-1 RabMAb 100µl, FC, IP Human $250 MKK4 1650-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $250 MKK4 (C-term) 1658-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 MKK5 1789-1 RabMAb 100µl, ICC Human $250 MKK6 (C-term) 1821-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 MKK6 (N-term) 1640-1 RabMAb 100µl, IP Human, Mouse, Rat $250 MKK7 (C-term) 1949-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 MKP-3 2138-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 MLCK 2095-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 New MLH1 2786-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 MLK-3 (C-term) 2000-1 RabMAb 100µl, ICC, FC Human, Mouse $250 MMP Family Sampler Kit 5006-1 RabMAb 40µl per vial, IHC, ICC, FC, IP Human, Mouse, Rat $595 Left: IHC using MMP-8 on human placenta (cat# 2145-1) Right: ICC using MMP-2 on HeLa cells (cat# 1842-1) Matrix Metalloproteases (MMPs) are a family of 25 endoproteases expressed in mammals known to degrade extracellular matrix and basement membrane components. MMPs are expressed as inactive zymogens, and are secreted from many connective tissues and pro-inflammatory cells. MMPs have been shown to be highly connected with a variety of diseases, including arthritis, inflammation, cancer, angiogenesis, atherosclerosis, cardiac diseases, stroke, ocular diseases, gastrointestinal diseases, and oral diseases. Kit Description: A sampler kit containing Rabbit Monoclonal antibodies for 10 proteins of the MMPs family (MMP 1, 2, 3, 9, 11, 12, 13, 14, 17, and 21). MMP-1 1973-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 MMP-1 1976-1 RabMAb 100µl, IP Human $250 MMP-2 1842-1 RabPAb 100µl, IHC, ICC, FC, IP Human $250 MMP-2 1948-1 RabMAb 100µl Human, Mouse, Rat $210 MMP-2 (Propeptide) 2008-1 RabMAb 100µl Human $210 New MMP-2 2763-1 RabMAb 100µl, FC Human $250 on (A) human spleen, (B) PMBC, (C) HL 60 IHC on human cervical carcinoma MRP8/S100A8 and MRP14/S100A9 are members of the S100 family proteins containing two EF-hand calcium-binding motifs. By a Ca2+ dependent manner S100A8/A9 forms Calprotectin, a heterodimeric inflammatory mediator of inflammation found in the cytoplasm of neutrophils and expressed on the membrane of monocytes. In cancer, MRP8/S100A8 has been linked inflammation-associated cancer and a therapeutic target for breast cancer. S100A8 is expressed myeloid differentiation, in chronic inflammations, and expressed constitutively or induced in epithelial cells during dermatose. Elevated serum level of S100A8 has been linked to various inflammatory disorders including cystic fibrosis, rheumatoid arthritis, and chronic bronchitis Specificity: A synthetic peptide corresponding to N-terminal region of human MRP8 / S100A8 was used as an immunogen. New MRP14 / S100A9 2738-1 RabMAb 100µl, IHC, ICC Human $250 New MRP14 / S100A9 2845-1 RabMAb 100µl, IHC Human $250 MP1 (C-term) 1525-1 RabMAb 100µl, IHC, ICC, IP Human $250 New MSH2 2848-1 RabMAb 100µl, IHC, ICC, FC Human $250 New MSH2 2857-1 RabMAb 100µl, ICC, IP Human $250 New MSH6 2846-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 MSK1 Phospho (ps360) 2154-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $285 MSK1 Phospho (ps376) 1611-1 RabMAb 100µl, IHC, ICC, IP Human $285 Mst1 1941-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Mst1 (pt183)/mst2 (pt180) Phospho 2111-1 RabMAb 100µl Human $285 Mst2 1943-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Mst3 1964-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Mst4 2049-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Mst4 (pt178)/mst3 (pt190)/stk25 (pt174) Phospho 2160-1 RabMAb 100µl, ICC Human $285 mtor 1612-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Mu type Opioid Receptor 1959-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 New MUC1 2900-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 MUC1 isoform 7 1797-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 Musashi 1 1877-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Rat $250 Musashi 2 2396-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 38 39

Myoglobin 2472-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 New Myoglobin 2717-1 RabMAb 100µl Human $210 New Myosin Light Chain 2 2742-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 Myosin RLC (N-term) 2159-1 RabPAb 100µl, ICC, IP Human $250 Myosin RLC (N-term) 2277-1 RabMAb 100µl, ICC, FC Human $250 MYPT1 (N-term) 1519-1 RabMAb 100µl, ICC Human $250 MYPT1/MYPT2 (C-term) 1488-1 RabMAb 100µl, ICC, IP, FC Human, Mouse, Rat $250 N Na+/K+ ATPase α 2047-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 N NAK/TBK1 (N-term) 1670-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 N-Cadherin 2447-1 RabMAb 100µl Human, Mouse, Rat $210 N-Cadherin (C-term) 2019-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 NCAM 2690-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 NCAM 2433-1 RabMAb 100µl, ICC, FC, IP Human $250 Nck 1622-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 NDUFAF1 2587-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 ICC on HeLa IHC on human liver NDUFAF1 (CIA30) is a chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex 1). Complex I is the largest multiprotein enzyme located in the inner mitochondrial membrane that catalyzes the transfer of electrons from NADH to coenzyme Q (CoQ). NDUFAF1 expression is ubiquitous with a slightly higher expression in various heart tissues, kidney, lung and liver. Specificity: A synthetic peptide corresponding to residues at the C terminus of human NDUFAF1 was used as an immunogen. NDUFAF1 2651-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 NEDD8 (N-term) 1571-1 RabMAb 100µl, IHC, ICC, IP Human $250 New NEK2 2913-1 RabMAb 100µl Human $210 Nephrin Phospho (py1176/1193) 2452-1 RabMAb 100µl, IP Human, Mouse $285 Nephrin Phospho (py1217) 2423-1 RabMAb 100µl, IP Human, Mouse $285 Neurofilament 66 1674-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Rat $250 Neurofilament 66 1707-1 RabMAb 100µl, IHC, ICC Human, Rat $250 Neurofilament 66 1897-1 RabPAb 100µl, FC, IP Human, Mouse, Rat $250 Neurofilament L (C-term) 1815-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 New Neurofilament M 2700-1 RabMAb 100µl, IHC, ICC, IP Human $250 NF-kB p105/p50 1559-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 NGF (Beta) 1895-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 NGF (Beta, Precursor) 2347-1 RabMAb 100µl, ICC, FC, IP Human, Mouse, Rat $250 NGF Receptor 1812-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Nibrin 1507-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 Nibrin Phospho (ps343) 2194-1 RabMAb 100µl, ICC, IP Human $285 Nicastrin 2332-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 Nm23-H1 (NDPK-A) 2578-1 RabMAb 100µl, IHC, ICC Human $250 NMDAR2B Phospho (ps1303) 2514-1 RabMAb 100µl Human, Mouse $285 nnos 2081-1 RabMAb 100µl, IHC, IP, FC Human, Mouse, Rat $250 Nodal 2148-1 RabMAb 100µl, FC Human, Mouse $250 NOG1 2608-1 RabMAb 100µl, IHC, FC, IP Human $250 Noggin 2021-1 RabPAb 100µl, FC, IP Human $250 NOTCH1 1935-1 RabMAb 100µl, IHC, ICC Human, Mouse $250 NPM (N-term) 2041-1 RabMAb 100µl, IHC, FC, IP Human $250 NPM Phospho (pt199) 2082-1 RabMAb 100µl, IHC, ICC, IP Human $285 NQO1 (C-term) 2558-1 RabMAb 100µl, IP Human $250 NQO1 (N-term) 2618-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 Nrf2 2178-1 RabMAb 100µl, IHC, ICC, IP Human $250 Nrf2 Phospho (ps40) 2073-1 RabMAb 100µl, IHC, ICC, IP Human $285 Nur77 2518-1 RabMAb 100µl, FC Human $250 O OCA-B 2553-1 RabMAb 100µl, IHC, ICC Human $250 O New OCA-B 2765-1 RabMAb 100µl Human $250 Oct-2 1663-1 RabPAb 100µl, IHC, FC Human $250 Oct-2 1663-1 RabMAb 100µl, IP Human $250 Oct-2 2652-1 RabMAb 100µl, IHC, ICC, FC Human $250 New Oct-4 2876-1 RabMAb 100µl, IHC, FC, IP Human $250 Octamer transcription factor-4 (Oct-4) is a homeodomain transcription factor in the POU transcription factor family that specifically binds to the octamer motif (5 -ATTTCAT-3 ) (1). It is critical for early embryogenesis and for embryonic stem cell pluripotency, expressed mainly in the developing brain. OCT4 is a master regulator that affects the fate of pluripotent stem cells and germ cell precursors. Specificity: A synthetic peptide corresponding to residues in human Oct-4 was used as an immunogen Neuofilaments (NF) are members of the intermediate filament protein family also known as 10nm filaments. These neuron-specific filaments are the major constituents of the axonal cytoskeleton. NFs are composed of three major proteins; NF-H, NF-M and NF-L and the ratio of each protein changes during neuronal development. NF-H is the heavy molecular weight protein (200 kda), NF-M the medium (160 kda) and NF-L the light protein (68kDa). IHC ovarian dysgerminom Op18 Phospho (ps24) 2171-1 RabMAb 100µl Human, Mouse, Rat $285 New OTX2 2807-1 RabMAb 100µl Human $210 ICC on SH-SY-5Y IHC on normal human brain Specificity: A synthetic peptide corresponding to residues in human Neurofilament M was used as an immunogen. New OTX2 2808-1 RabMAb 100µl, IHC Human $250 OX40L 2369-1 RabMAb 100µl Human $210 Neurofilament M Phospho (ps614/619) 2275-1 RabMAb 100µl, IP Human $285 Neuropilin-1 2621-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 New NFAT1 2740-1 RabMAb 100µl Human $210 NF-kB p65 1546-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 NF-kB p65 2229-1 RabMAb 100µl, ICC, FC Human $250 NF-kB p65 Phospho (ps536) 2220-1 RabMAb 100µl, IP Human $285 OX40 2359-1 RabMAb 100µl Human $210 P p16 1712-1 RabMAb 100µl, FC, IP Human $250 P p16 1963-1 RabMAb 100µl, IHC, ICC, FC Human $250 p16-arc (N-term) 1961-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 New p120 Catenin 2806-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 p190-b RhoGAP 1628-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 p21 1548-1 RabMAb 100µl, ICC Human $250 40 41

p21 1819-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 p21 Phospho (ps145) 2674-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 IHC on human gastric carcinoma p21 binds to and inhibits CDK activity, preventing phosphorylation of critical CDK substrates and blocking cell cycle progression. p21 is suggested to possibly be the important intermediate by which p53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Phosphorylation of Threonine 144 by Akt or of Serine 145 by PKC impairs p21 binding to PCNA. Specificity: A phospho-specific peptide corresponding to residues surrounding Serine 145 of human p21 was used as an immunogen. on 293T. Cells were either (A) untreated (B) treated with LP New p27 2747-1 RabMAb 100µl, IHC Rat $250 New p27 2814-1 RabMAb 100µl Human $210 p27 (C-term) 1591-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Rat $250 p27 Phospho (ps10) 2187-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $285 New P2Y6 2733-1 RabMAb 100µl, IHC, ICC, IP Human $250 p38 - See Crk p38 MAPK 1544-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 p38 MAPK Phospho (pt180/py182) 1229-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $285 p40 2124-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 p44 MAPK (N-term) 1172-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Mouse, Rat $250 p53 1026-1 RabMAb 100µl, IHC, ICC Human, Rat $250 p53 (C-term) 1047-1 RabMAb 100µl, ICC, IP, FC Human $250 p53 (N-term) 1005-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $250 p53 Acetyl (K373) 2204-1 RabMAb 100µl, IHC, ICC Human $285 p53 Acetyl (K382) 2485-1 RabMAb 100µl, ICC Human $285 p53 Phospho (ps6) 1536-1 RabMAb 100µl, IHC, ICC, IP Human $285 p53 Phospho (ps9) 1551-1 RabMAb 100µl Human $285 p53 Phospho (ps33) 2262-1 RabMAb 100µl, ICC Human $285 p53 Phospho (ps46) 2190-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 p53 acts as both a tumor-suppressor and transcription factor that, upon activation by DNA damage and other cellular stress signals, leads to the transcription of genes triggering cell-cycle arrest, apoptosis, and DNA repair. p53 is frequently mutated or inactivated in about 60% of cancers. Phosphorylation on serine 46 has been implicated as a mediator in apoptosis induced by DNA-damage p80 - See Alk p95 NBS1 Phospho (ps432) 2407-1 RabMAb 100µl, IHC, ICC Human $285 p115 2269-1 RabMAb 100µl, IP Human, Mouse, Rat $285 p120 Catenin 1506-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 p120 Catenin Phospho (py96) 2503-1 RabMAb 100µl Human $285 p120 Catenin Phospho (py228) 1205-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 p120 Catenin Phospho (py291) 2270-1 RabMAb 100µl Human $285 p120 Catenin Phospho (pt268) 2572-1 RabMAb 100µl, IHC, ICC Human $285 p120 Catenin Phospho (pt310) 2542-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $285 p120 Catenin Phospho (pt916) 2611-1 RabMAb 100µl, IHC, ICC Human $285 p130 - See Rb2 p130 See Rb2 New p130cas Phospho (py410) 2773-1 RabMAb 100µl, IP Human $285 Breast cancer anti-estrogen resistance protein 1 (p130cas) is a docking protein that plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion (1). It has defined function in cardiovascular development, actin filament assembly and Src-induced transformation (2). p130cas is highly phosphorylated at tyrosines during transformation by v-src, as well as by v-crk, forming stable complexes with these oncoproteins. Specificity: A synthetic peptide corresponding to residues surrounding Tyrosine 410 of human p130cas was used as an immunogen. on HeLa cell lysate A) untreated and B) treated with pervanadate PABP2 2428-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 PABP2 2494-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 PAEP 1992-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 PAK1 1705-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 PAK1 (N-term) 1734-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PAK1 Phospho (ps20) 1990-1 RabMAb 100µl, IP Human $285 PAK2 2247-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 PAK2 Phospho (ps20) 2459-1 RabMAb 100µl, ICC Human $285 PAK3 (N-term) 1717-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 PAK4 (N-term) 1725-1 RabPAb 100µl Human, Mouse, Rat $210 New PAK4 (C-term) 2779-1 RabMAb 100µl, IP Human, Mouse $250 IHC on ovarian adenocarcinoma Specificity: A synthetic phospho-peptide corresponding to residues surrounding Serine 46 of human p53. on HepG2 cells lysate. Cells were either (A) untreated (B) treated with etopside New PAR4 2853-1 RabMAb 100µl, IP Human, Mouse $250 Parkin 1679-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 PARP-1 (Cleaved p25) 1051-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 p53 Phospho (ps392) 1644-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $285 PARP-1 (Cleaved p85) 1074-1 RabMAb 100µl, ICC, IP, FC Human, Rat $250 p53 Phospho (ps392) 2326-1 RabMAb 100µl, IHC, ICC, IP Human $285 PARP-1 (p116) 1077-1 RabMAb 100µl, IP Human $250 p56 - See Lck PARP-1 (p116/p25) 1072-1 RabMAb 100µl, IHC, ICC, FC Human, Rat $250 p57 2372-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PARP-1 (p116/p85) 1078-1 RabMAb 100µl Human $210 New p57 2723-1 RabMAb 100µl Human $210 p58 1903-1 RabMAb 100µl Human $210 Parvin Phospho (ps8) 2607-1 RabMAb 100µl, ICC Human, Mouse, Rat $285 PAX2 2549-1 RabMAb 100µl, IHC, FC Human, Mouse $250 p63 / p73l (C-term) 1555-1 RabMAb 100µl, ICC, IP Human $250 New PAX5 2804-1 RabMAb 100µl, ICC Human $250 p70 S6 Kinase (N-term) 1494-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 PAX7 2766-1 RabMAb 100µl Human $250 p70 S6 Kinase Phospho (pt389) 1175-1 RabMAb 100µl, IHC, IP Human, Mouse $285 Paxillin (N-term) 1500-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 p70 S6 Kinase Phospho (pt421/ps424) 1135-1 RabMAb 100µl, IP Human $285 p73 1636-1 RabMAb 100µl, IHC. ICC, IP Human, Mouse, Rat $250 Paxillin Phospho (py31) 1228-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $285 Paxillin Phospho (py181) 2128-1 RabMAb 100µl, IHC, ICC, IP Human $285 42 43

PBK 2286-1 RabMAb 100µl, IP Human $250 PBK (C-term) 2287-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 New PCNA 2714-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 PKA RIIb 2385-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PKA RIIb 2550-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 PKA RIIb Phospho (ps114) 2634-1 RabMAb 100µl, ICC Human, Mouse $285 Left: ICC on HeLa Middle: IHC on human tonsil Right: on (A) HeLa (B) HepG2 (C) 293T, (D) A431 PCNA is a DNA polymerase accessory factor that is required for DNA replication during S phase of the cell cycle and for resynthesis during nucleotide excision repair of damaged DNA. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Specificity: A synthetic peptide corresponding to residues in human PCNA was used as an immunogen. PKC Phospho (Beta II, ps660) 2252-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 PKC (Alpha) 1608-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PKC (Alpha, C-term) 1510-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PKC (Beta II) 1514-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PKC (Delta) 2053-1 RabMAb 100µl, IHC, ICC, FC Human $250 New PKC (Gamma) 2878-1 RabMAb 100µl Human, Mouse, Rat $210 PKC (Mu) 1986-1 RabMAb 100µl Human, Mouse, Rat $210 New PCNA 2755-1 RabMAb 100µl, IHC, FC Human $250 PKC (Theta) 2040-1 RabMAb 100µl Human, Mouse, Rat $210 PDCD4 2606-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse $250 PKC Phospho (Alpha, pt497) 2378-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 PDCD4 2619-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 PDCD6 2630-1 RabMAb 100µl Human $250 PDGF Receptor (Beta, C-term) 1469-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 PDGF Receptor Phospho (Beta, py1009) PDGF Receptor Phospho (Beta, py740) 2404-1 RabMAb 100µl Mouse $285 2213-1 RabMAb 100µl, ICC Mouse $285 ICC on HeLa cell lysate.(left) IHC on human kidney (Right) Activation of PKC plays a crucial role in tranducing signals for a variety of cellular responses, including tumor proliferation. PKC isoforms have been classified into three groups: classical, novel, and atypical. Members of these three PKC groups contain an autoinhibitory domain that binds to the substrate binding site in the catalytic domain, preventing its activation in the absence of cofactors or activators. The activity of PKC is under the control of three distinct phosphorylation events, including that of the Thr641 autophosphorylation site. Specificity: A phospho specific peptide corresponding to residues surrounding threonine 497 of human PKC alpha was used as an immunogen. PDGF Receptor Phospho (Beta, py857) 2197-1 RabMAb 100µl Mouse $285 PDK1 1624-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 PDK1 1901-1 RabMAb 100µl, IHC Human, Mouse $250 PDK2 2115-1 RabMAb 100µl, IHC, ICC, FC Human $250 PDK2 2282-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PDZK1 2679-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 PDZK1 2697-1 RabMAb 100µl, IHC, ICC Human $250 New Peroxiredoxin 6 2726-1 RabMAb 100µl, IHC, ICC, FC Human $250 PKC Phospho (Alpha, pt638) 1195-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 PKC Phospho (Delta, pt507) 2087-1 RabMAb 100µl Human $285 PKC Phospho (Delta, py311) 2441-1 RabMAb 100µl, IHC IP Human, Mouse $285 PKC Phospho (Gamma, pt514) 2400-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 PKC Phospho (Mu, ps744/748) 2328-1 RabMAb 100µl, IP Human $285 PKC Phospho (Mu, ps916) 2085-1 RabMAb 100µl, IHC, IP Human $285 PKC Phospho (Zeta, pt560) 2200-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 PKC Phospho (Zeta, Lambda, pt410/403) 2106-1 RabMAb 100µl, IHC, ICC Human $285 New Peroxiredoxin 6 2769-1 RabMAb 100µl, IHC, ICC, IP Human $250 PKN1 2522-1 RabMAb 100µl, FC Human $250 New PHD1 2774-1 RabMAb 100µl, ICC, FC Human $250 PKN1 2662-1 RabMAb 100µl, IHC, ICC, IP Human $250 New PHD1 2872-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 PKR (C-term) 1511-1 RabMAb 100µl, IHC, ICC, IP Human $250 Phox - See p40 PKR (N-term) 1508-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 New Phospholamban Phospho (ps16) 2727-1 RabMAb 100µl, IP Human Mouse $285 PKR Phospho (pt446) 1120-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $285 PI3-kinase p110 subunit (Alpha) 1683-1 RabMAb 100µl, ICC, IP Human $250 PKR Phospho (pt451) 2283-1 RabMAb 100µl Human $285 PI3-kinase p110 subunit (Beta, N-term) 1593-1 RabMAb 100µl, FC, IP Human $250 PI3-kinase p110 subunit (Delta) 1575-1 RabMAb 100µl, ICC, IP Human $250 PI3-kinase p110 subunit (Gamma, N-term) 1605-1 RabMAb 100µl, FC, IP Human $250 PLAP 1566-1 RabMAb 100µl, IHC, ICC Human $250 PLAP 4206-1 RabMAb 100µl IHC Human $205 PLC β III Phospho (ps1105) 2020-1 RabMAb 100µl Human $285 PLC γ I 2112-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $250 PI3-kinase p85 subunit (Alpha, C-term) 1675-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Rat $250 PLC γ I (C-term) 2278-1 RabMAb 100µl Human $210 PIAS1 (C-term) 2474-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PLC γ I Phospho (py771) 2350-1 RabMAb 100µl Human $285 Pim1 2409-1 RabMAb 100µl, IHC, ICC Human $250 PLC γ I Phospho (py783) 2104-1 RabMAb 100µl, ICC Human $285 Pin1 2136-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 PLC γ I Phospho (py783) 2325-1 RabMAb 100µl, ICC Human $285 Pin1 Phospho (ps16) 2161-1 RabMAb 100µl, ICC Human $285 PLC γ I Phospho (py1245) 2125-1 RabMAb 100µl, ICC Human $285 PKA C (Alpha) 2113-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PLC γ II 2188-1 RabMAb 100µl Human $210 PKA C Phospho (Gamma, pt197) 2383-1 RabMAb 100µl, IHC ICC, IP Human, Mouse, Rat $285 PLC γ II Phospho (py1197) 2263-1 RabMAb 100µl, ICC, IP Human $285 PKA RII (C-term) 1528-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 PLC γ II Phospho (py1217) 1931-1 RabMAb 100µl, IHC, IP Human $285 PKA RII Phospho (ps96) 1151-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 PLC γ II Phospho (py759) 1938-1 RabMAb 100µl, ICC, IP Human $285 44 45

PLD1 (N-term) 2315-1 RabMAb 100µl, ICC, FC Human, Mouse $250 Plectin 1399-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 Pleiotrophin 2615-1 RabMAb 100µl, IP Human, Mouse, Rat $250 Plexin-A1 2627-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 Plexins are large transmembrane receptors for semaphorins. It contains a sema domain and a highly conserved cytoplasmic domain. Plexins are classified into four groups: A, B, C, D. Plexin-A1 is a co-receptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plexin-A1 plays a role in axon guidance, invasive growth and cell migration. Plexin-A1 modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. Plexin-A1 is specific in fetal brain, lung, liver and kidney. Specificity: A synthetic peptide corresponding to residues in human Plexin-A1 was used as an immunogen. on (A) K562 (B) 293T (C) HUVEC (D) HepG2 cell lysates and (E) Fetal Brain tissue lysates Pol II 2035-1 RabMAb 100µl, ICC, FC Human $250 Pol II Phospho (ps1801) 2245-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 Polyethylene Glycol (PEG) 2061-1 RabMAb 100ug, ELISA, IHC $225 Polyethylene Glycol (PEG)-Biotin 2137-1 RabMAb 100ug, ELISA, IHC $305 New PON1 2844-1 RabMAb 100µl, IHC, IP Human $250 IHC on breast adenocarcinoma Paraoxonase 1 (PON 1) is an esterase and lactonase that is synthesized in the liver and secreted into blood, associated exclusively with high density lipoproteins (HDL). It hydrolyzes the toxic oxon metabolites of several organophosphorous insecticides and nerve agents. This protein has been implicated in protection from atherosclerosis. Specificity: A synthetic peptide corresponding to residues near the N-terminus in human PON 1 was used as an immunogen. Pou Domain Protein 3A 2083-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PP1 (Alpha) 1950-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 PP1 (Beta) 2029-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 PP1 Phospho (Alpha, pt320) 2167-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $285 PP2A 1512-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 PP2A (N-term) 1504-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 PP2A Phospho (py307) 1155-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $285 PP2B (N-term) 2051-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 PP2C (Alpha) 2157-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PR 1483-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $250 PR Phospho (ps190) 2258-1 RabMAb 100µl, IHC, ICC, IP Human $285 PRA1 (C-term) 2140-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 PRK2 1498-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PRKDC 1579-1 RabMAb 100µl, IHC, ICC Human $250 PRMT1 2629-1 RabMAb 100µl, IHC Human, Mouse $250 Prohibitin (C-term) 2413-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 Prohibitin (N-term) 2410-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 New Prolactin 2754-1 RabMAb 100µl Human $210 New Prostaglandin E Synthase 3 2731-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $250 Prostate-Specific Antigen (PSA) 1984-1 RabMAb 100µl, IHC Human $250 IHC on prostate carcinoma Prostate-specific antigen (PSA, Kallikrein-3, KLK3) is a serine protease that is usually secreted from the prostate gland and presented in seminal plasma. PSA function in the liquefaction of seminal coagulum, through hydrolysis of the high molecular mass seminal vesicle protein. Its substrates includes semenogelin I & II, fibronectin, insulin-like growth factor binding protein 3 (IGBP3), and laminin. Highly expressed by normal and malignant prostate cancer cells, PSA has been implicated in the growth, invasion, and metastasis of prostate cancer cells. Therefore, PSA is widely used as a diagnostic marker for prostate cancer. Recently, PSA has been suggested as an endothelial cell-specific inhibitor of angiogenesis. Specificity: A synthetic peptide corresponding to residues near the C-terminal of human PSA. Protein Kinase D2 1969-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse $250 Protein Kinase D2 Phospho (ps876) 1962-1 RabMAb 100µl, IP Human $285 PSD95 2366-1 RabMAb 100µl, ICC, FC, IP Human, Mouse, Rat $250 PSD95 Phospho (ps295) 2362-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $285 PSD95 Phospho (ps418) 2393-1 RabMAb 100µl Human, Mouse, Rat $285 P-Selectin Glycoprotein Ligand 1 2335-1 RabMAb 100µl, ICC, IP Human $250 PSMA 2556-1 RabMAb 100µl, FC, IP Human $250 PSMA 2571-1 RabMAb 100µl, ICC Human $250 PTEN (C-term) 1539-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PTEN Phospho (ps380) 2143-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 PTEN Phospho (pt366/ps370) 2195-1 RabMAb 100µl, IHC, ICC, IP Human $285 PTP1B 2066-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 PTP1B 2257-1 RabMAb 100µl, IHC, ICC, FC Human $250 PTP1B Phospho (ps352) 2166-1 RabMAb 100µl, ICC, IP Human $285 PTP1B Phospho (ps378) 2163-1 RabMAb 100µl, IHC, ICC Human $285 PTP1B Phospho (ps50) 2179-1 RabMAb 100µl Human $285 PUMA (C-term) 1652-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 New Pumilio-1 2705-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 New Pumilio-2 2725-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $250 Pyk2 - See FAK2 PRC1 1965-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Moues, Rat $250 PRC1 Phospho (pt481) 2189-1 RabMAb 100µl, IHC, ICC Human $285 Prealbumin 2524-1 RabMAb 100µl, IHC, FC Human $250 Presenilin 1 2094-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Presenilin 1 2158-1 RabMAb 100µl, FC Human, Mouse, Rat $250 Presenilin 1 Phospho (ps310) 2370-1 RabMAb 100µl, ICC Human $285 Presenilin 2 1987-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Presenilin 2 Phospho (ps327) 2365-1 RabMAb 100µl, IP Human, Mouse, Rat $285 Presenilin 2 Phospho (ps330) 2352-1 RabMAb 100µl Human, Mouse, Rat $285 Q Quinone Reductase 1 / NQO1 2558-1 RabMAb 100µl, IP Human $250 Q NQO1(Quinone reductase 1) is a flavoenzyme that catalyzes two-electron reductive metabolism and detoxification of quinones and their derivatives leading to protection of cells against redox cycling and oxidative stress. NQO1/Quinoni 1 is mainly cytosolic, but its nuclear presence suggests its involvement in both chemoprevention and bioactivation of DNA-damaging antitumor agents. NQ01/Quinoni 1 may also play a role in the bioactivation of antitumor quinones such as mitomycin C (MMC), and has been proposed to have a protective effect against cancer caused by quinones and their metabolic precursors. Specificity: A synthetic peptide corresponding to the C-terminus of human NQO1 (Quinone reductase 1) was used as an immunogen. on (A) MCF-7, (B) HeLa, (C) A549 and (D) HepG2 cell lysates Prion Protein (PrP) 2063-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 R New RAB27A 2903-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Rat $250 R Rab4 2632-1 RabMAb 100µl, ICC, FC Human $250 Rac 1 - See Cdc42 46 47

Rad17 Phospho (ps645) 2415-1 RabMAb 100µl Human $285 Rad17 Phospho (ps656) 2554-1 RabMAb 100µl, IHC, ICC Human $285 RIAM 2455-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 RIAM 2698-1 RabMAb 100µl, IHC, icc, IP Human, Mouse $250 Radixin 2042-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Raf-1 1560-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 RAIDD 2508-1 RabMAb 100µl, FC, IP Human, Rat $250 RAIDD (C-term) 1957-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 RanBP9 (C-term) 1928-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 New RanGAP1 2771-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Rap1 2291-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $250 Rap1 1726-1 RabPAb 100µl, IHC, FC Human, Mouse, Rat $250 Ribosomal Protein S6 Phospho (ps235/236) IHC on breast adenocarcinoma 2268-1 RabMAb 100µl, IHC, ICC, IP Human $285 Ribosomal protein S6 (RPS6) belongs to S6E family of ribosomal proteins and it is involved in the control of cell growth and proliferation via selective translation. It is a major substrate of Ribosomal Protein S6 Kinase (RSK) in the eukaryote ribosomes. The phospholyation of RPS6 has been linked to increase in selective 5 TOP translation. Specificity: A synthetic peptide corresponding to residues surrounding serine 235/236 of human Ribosomal Protein S6 was used as an immunogen. on HeLa cells lysate. Cells were either (A) untreated (B) treated with Calyculin A Rap1GAP (C-term) 1520-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Rap1GAP (N-term) 1530-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Raptor 1689-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 RAR (Alpha) 2086-1 RabMAb 100µl, FC Human, Mouse $250 Ras - See p21 RasGap 1671-1 RabMAb 100µl, IHC, ICC Human, Rat $250 RasGAP (C-term) 1715-1 RabPAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 RAX / PRKRA 2490-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 Rb 2655-1 RabMAb 100µl Human $210 Retinoblastoma tumor suppressor protein (Rb) is associated with DNA binding activity and is thought to play a significant role in controlling cell cycle progression during tumor growth. Cell cycle-dependent phosphorylation by cdk s inhibits Rb binding, thus allowing cell cycle progression. Rb inactivation and cell cycle progression likely requires first phosphorylation by cyclin D-cdk4/6 followed by cyclin E-cdk2 phosphorylation Specificity: A synthetic peptide corresponding to residues in human Rb was used as an immunogen. on (A) Jurkat and (B) K562 Rb Phospho (ps780) 1182-1 RabMAb 100µl, ICC, IP Human $285 Rb Phospho (pt356) 2223-1 RabMAb 100µl, IHC, ICC, IP Human $285 Rb Phospho (pt373) 1807-1 RabMAb 100µl, IHC, ICC, IP Human $285 Rb Phospho (pt821) 1231-1 RabMAb 100µl, ICC, IP Human $285 Rb2 2130-1 RabMAb 100µl, IHC, FC Human $250 RKIP 2460-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 RKIP Phospho (ps153) 2445-1 RabMAb 100µl, IHC, ICC Human, Rat $285 ROCK1 1761-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 ROCK1 1953-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Ron 1830-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 New ROR2 2722-1 RabMAb 100µl, ICC, FC Human $250 RPA32 2461-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 RPA70 2589-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 RPA 70 2609-1 RabMAb 100µl, FC, IP Human $250 RSK1 (C-term) 1473-1 RabMAb 100µl, IP Human, Mouse, Rat $250 RSK1 (N-term) 2004-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Mouse, Rat $250 RSK1 Phospho (ps380) 1468-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $285 RSK1 Phospho (pt359/ps363) 2006-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $285 RSK1 Phospho (pt573) 2185-1 RabMAb 100µl Human $285 RSK2 (C-term) 1474-1 RabMAb 100µl, IHC, FC, IP Human, Rat $250 RSK2 (N-term) 1482-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 RSK2 Phospho (ps227) 2440-1 RabMAb 100µl, IP Human, Mouse, Rat $285 RSK3 Phospho (pt353/356) 2012-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $285 RSK4 (N-term) 2102-1 RabMAb 100µl, IHC, ICC, FC Human $250 RSK4 Phospho (ps235) 2151-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse $285 New RUNX1 2813-1 RabMAb 100µl, IHC Human, Mouse $250 Rb2 Phospho (ps672) 2226-1 RabMAb 100µl, IP Human $285 Rb2 Phospho (ps952) 2272-1 RabMAb 100µl, IHC, ICC Human, Mouse $285 RelB 1661-1 RabMAb 100µl, IHC, ICC, IP Human $250 RBBP4 2566-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 RBBP4 2599-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 RelB (C-term) 1653-1 RabMAb 100µl, FC, IP Human $250 Rest 2417-1 RabMAb 100µl, FC Human $250 IHC on breast adenocarcinoma RUNX1 (PEBP2-alpha B, Runt-related transcription factor 1, AML1) is a pivotal transcription factor essential for haematopoietic stem cell generation in the vascular regions of the aorta, vitelline and umbilical arteries, yolk sac and placenta. So far, 11 isoforms of RUNX1 has been reported. It binds DNA in cooperation with CBFbeta to activate or repress transcription, dependent upon cellular context and interaction with a variety of co-activators and co-repressors. Specificity: A synthetic peptide corresponding to residues in human RUNX1 was used as an immunogen. IHC on human tonsil (Left) on (A) Molt-4, (B) fetal thymus and (C) mouse thymus (Right) RGS9 2661-1 RabMAb 100µl, ICC, FC, IP Human $250 Rheb 2635-1 RabMAb 100µl, IHC, ICC, FC Human $250 Rho 1667-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Rho (N-term) 1600-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 New Rho GDI 2751-1 RabMAb 100µl, ICC Human $250 RUNX1 2593-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 New RUVBL2 2889-1 RabMAb 100µl Human, Mouse $210 S S100 (Beta, C-term) 2017-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $250 S New S100A6 2870-1 RabMAb 100µl, ICC, FC, IP Human, Mouse $250 S100A10 2595-1 RabMAb 100µl, IHC, ICC, IP Human $250 SAM68 2529-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 New SATB1 2781-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 New SATB2 2819-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 New SCARF1 2782-1 RabMAb 100µl, IHC, ICC, IP Human $250 48 49

SCF 2062-1 RabMAb 100µl, IHC, ICC, FC Human $250 Securin 2603-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 SEK - See MEKK4 New SENP1 2887-1 RabMAb 100µl, IHC, ICC Human $250 New Serum amyloid A4 (SAA4) 2701-1 RabMAb 100µl, IHC, ICC, FC Human $250 IHC on normal human kidney Serum amyloid A (SAA) proteins are family of apolipoproteins of high density lipoprotein (HDL). SAA4 and SAA5 exist as the minor apolipoproteins on HDL, but this group of SAA constitutes more than 90% of all the SAA during homeostasis, and it is thought to play a role in the normal functioning of the HDL particle (1, 2). The distribution of SAA4 is restricted to two lipoprotein subclasses; therefore, SAA4 has been suggested be a factor in lipid transfer between lipoprotein classes. Specificity: A synthetic peptide corresponding to residues near the C-terminal of human SAA4 was used as an immunogen. New Serum amyloid A4 (SAA4) 2701-1 RabMAb 100µl, IHC, ICC, FC Human $250 Serum amyloid P-component 1753-1 RabPAb 100µl, IHC Human, Mouse, Rat $250 Serum amyloid P-component (N-term) 1793-1 RabMAb 100µl, IHC Human $250 SGK 1617-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 SHC1 1629-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 SHC1 Phospho (py239/40) 2196-1 RabMAb 100µl Human $285 SHC1 Phospho (py427) 2333-1 RabMAb 100µl Human, Mouse, Rat $285 SHIP 1786-1 RabMAb 100µl, IHC, FC, IP Human $250 SHIP 1803-1 RabPAb 100µl, IHC, IP Human $250 SHIP Phospho (py1020) 2787-1 RabMAb 100µl, IHC, IP Human $285 SHP-1 (C-term) 1606-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 SHP-2 1590-1 RabMAb 100µl, IHC, IP Human $250 SHP-2 1609-1 RabMAb 100µl, IP Human, Mouse, Rat $250 SHP-2 Phospho (py542) 2184-1 RabMAb 100µl, ICC, IP Human, Mouse $285 SHP-2 Phospho (py582) 2165-1 RabMAb 100µl Human $285 SIRT1 1104-1 RabMAb 100µl, IHC, ICC, IP Human $250 SIRT1 (N-term) 1054-1 RabMAb 100µl, IHC, ICC, IP, FC Human $250 SIRT1 Phospho (ps27) 2451-1 RabMAb 100µl, IP Human $285 SIRT1 Phospho (ps47) 2381-1 RabMAb 100µl, IHC, ICC Human $285 SIRT2 2536-1 RabMAb 100µl Human $210 SIRT2 (C-term) 1999-1 RabMAb 100µl, ICC, FC, IP Human $250 SKP1 2538-1 RabMAb 100µl, FC Human, Mouse, Rat $250 SKP1 2617-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 IHC on human brain SKP1 (S-phase kinase-associated protein 1) is a core component of the Skp1-Cullin-F-box (SCF) ubiquitin ligase protein complex. It mediates the ubiquitination of proteins involved in cell cycle progression, transcriptional regulation, and signal transduction. Independent of its function as a part of the SCF complex, SKP1 also functions in mitotic exit and cytokinesis. A possible contribution to the function of SKP1 in the mitotic exit is its physical interaction with Bfa1, a key negative regulator of the mitotic exit network. Specificity: A synthetic peptide corresponding to residues in human SKP1 were used as an immunogen. SLP-76 Phospho (py113) 2382-1 RabMAb 100µl, FC Human $285 SLP-76 Phospho (py145) 2419-1 RabMAb 100µl, ICC, FC Human $285 Smac/Diablo 1012-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Rat $250 Smad1 1649-1 RabMAb 100µl, ICC Human, Mouse $250 Smad2 1641-1 RabMAb 100µl, IHC, ICC, FC Human $250 Smad2 1736-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Rat $250 Smad3 1735-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $250 Smad3 Phospho (ps423/425) 1880-1 RabMAb 100µl, IHC, ICC Human, Rat $285 Smad4 (C-term) 1676-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Smad5 1682-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 Smad5 Phospho (ps463/465) 2224-1 RabMAb 100µl, ICC Human $285 ICC on HeLa Smad5 is a member of the Mothers Against Dpp (MAD)-related family of proteins. Smad 1, 5 and 8 serve as pathway-restricted Smads for the bone morphogenetic proteins (BMPs) signaling pathway. Smad5 is directly activated by BMP type Ia or Ib receptors upon BMP-2 stimulation and transduced BMP-2 signals to the nucleus by forming a complex with Smad 4, activating the transcription of the target gene in the nucleus. BMP activates Smad5 by phosphorylation at Ser463 and Ser465, which are the equivalent phosphorylation sites for Smad 1 and Smad 8. Specificity: A phospho specific peptide corresponding to residues surrounding Serine 463 and 465 of human Smad5. on HeLa cell lysate. Cells were either (A) untreated (B) treated with BMP-4 Smad5 Phospho (ps463/465) 2737-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 SMC1 Phospho (ps957) 2412-1 RabMAb 100µl, IHC, ICC Human $285 SMC1 Phospho (ps957) 2453-1 RabMAb 100µl, IHC, IP Human $285 SMC1 Phospho (ps966)) 2414-1 RabMAb 100µl, ICC Human $285 Smurf2 2078-1 RabMAb 100µl Human, Mouse, Rat $210 Smurf2 (IHC/ICC Specific) 1865-1 RabMAb 100µl IHC, ICC Human $250 SOD1 1926-1 RabPAb 100µl, IHC, ICC, IP Human $250 SOD1 2018-1 RabMAb 100µl, IHC, ICC, FC Human, Rat $250 SOD1 2582-1 RabMAb 100µl, IHC, ICC, IP Human $250 SOD2 2299-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 Somatostatin Receptor 2 / STT2 2604-1 RabMAb 100µl, IHC, ICC, IP, FC Human, Mouse, Rat $250 Sonic Hedgehog Protein / SHH (C-Product) 1843-1 RabMAb 100µl, IHC, FC, IP Human $250 SOX2 2683-1 RabMAb 100µl, IHC, ICC Human $250 SOX2 2696-1 RabMAb 100µl, IHC, IP Human $250 IHC on breast adenocarcinoma SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. It is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct3/4 expression. Specificity: A synthetic peptide corresponding to residues in human SOX2 was used as an immunogen. on NCCIT cell lysate SPP1 2671-1 RabMAb 100µl, IHC, ICC, FC Human $250 SR-B1 Scavenge Receptor 1971-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 Src 1587-1 RabMAb 100µl, IHC, ICC Human, Rat $250 Src 2778-1 RabMAb 100µl, IHC Human $250 Src Phospho (py529) 1550-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $285 ST13 2552-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse $250 ST13 2573-1 RabMAb 100µl, IHC, FC Human, Mouse $250 Stat-1 2728-1 RabMAb 100µl, FC, IP Human, Mouse $250 50 51

Stat-2 1513-1 RabMAb 100µl, IHC, ICC Human, Rat $250 Stat-2 2120-1 RabMAb 100µl, IHC, FC, IP Mouse $250 Stat-3 1122-1 RabMAb 100µl, IHC, ICC, IP Human $250 Stat-3 2281-1 RabMAb 100µl, ICC, IP Human, Mouse, Rat $250 Stat-3 Phospho (ps727) 1121-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $285 Stat-3 Phospho (py705) 2236-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $285 Stat-5 (Alpha, C-term) 1289-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Rat $250 Stat-5 Phospho (py694) 1208-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $285 Stat-6 1265-1 RabMAb 100µl, ICC, FC, IP Human $250 Stat-6 1505-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 Stathmin 1885-1 RabPAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Stathmin 1972-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Stathmin 2676-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Stathmin Phospho (ps62) 2532-1 RabMAb 100µl, IHC, IP Human $285 Sulfotransferase 1A3 / 1A4 2658-1 RabMAb 100µl. ICC, FC Human $250 SUMO-1 1563-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Left: ICC on HeLa Middle: IHC on human lung carcinoma Right: on (A) HeLa and (B) NIH3T3 Small ubiquitin-related modifier-1 (SUMO-1), also known as SMT3, Sentrin, GMP1 UBL1 and PIC1, is a member of the ubiquitin like family (1-2). Structurally similar to ubuquitin, SUMO-1 does not mark protein for degradation (SU- MOlation) but instead seems to be involved in the modulation of proteinprotein interaction. It also participates in a number of cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. SUMO-1 is also known to form a complex with RanGAP1. Specificity: A synthetic peptide corresponding to residues near the C-term of human SUMO-1 was used as immunogen. New SUMO-1 2708-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 Suppressor of Fused (SUFU) 1907-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Suppressor of Fused (SUFU) 2424-1 RabMAb 100µl, IHC, FC, IP Human $250 Survivin 2463-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Survivin 2565-1 RabMAb 100µl, IHC, ICC, FC Human $250 Syk 1688-1 RabMAb 100µl, IHC, ICC Human $250 Syk Phospho (py323) 2173-1 RabMAb 100µl, IHC, ICC Human $285 Syk Phospho (py525/526) 2175-1 RabMAb 100µl, IHC Human $285 Synapsin I Phospho (ps553) 1532-1 RabMAb 100µl, ICC Human, Mouse, Rat $285 Synapsin I Phospho (ps9) 2228-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $285 Synapstin II 2564-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Synaptojanin 2 2273-1 RabMAb 100µl, ICC, IP Human $250 Synaptophysin 1870-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Synaptophysin (C-term) 1485-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 SynGAP 2477-1 RabMAb 100µl, FC Human, Mouse, Rat $250 Synip 1668-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 Synuclein (Alpha) 2016-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 Synuclein Phospho (Alpha, ps129) 2014-1 RabMAb 100µl Human $285 T TAB1 2139-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 T Tau 2368-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 ICC on SH-SY5Y Tau is a microtubule binding protein that promotes microtubule assembly and stability. Tau is found to be the major component of the paired helical filaments (PHFs) found in the brains of patients with Alzheimer disease (AD). Tau is hyperphosphorylated in PHFs, and specific phosphorylation sites have been implicated in the loss of Taus association with the membrane cortex during AD disease state, including Ser 199/202, Thr 231, and Ser 393/404. Glycogen synthase kinase-3, or GSK-3, phosphorylates Tau on Ser 396. Specificity: A synthetic phospho-peptide corresponding to residues surrounding serine 622 of human Tau was used as an immunogen. Tau Phospho (ps396) 1178-1 RabMAb 100µl, IHC, ICC, IP Human, Rat $285 Tau Phospho (ps515) 2567-1 RabMAb 100µl, IHC, ICC, IP Human $285 Tau Phospho (ps516) 2511-1 RabMAb 100µl Human, Mouse, Rat $285 Tau Phospho (ps519) 2486-1 RabMAb 100µl, IP Human, Mouse, Rat $285 Tau Phospho (pt548) 2502-1 RabMAb 100µl, IP Human, Mouse, Rat $285 Tau Phospho (ps579) 2631-1 RabMAb 100µl Human $285 Tau Phospho (ps673) 2699-1 RabMAb 100µl, ICC Human $285 Tau Phospho (ps721) 2691-1 RabMAb 100µl, IHC Human, Mouse, Rat $285 Tau Phospho (ps739) 2612-1 RabMAb 100µl Human $285 TBK1 - See NAK TC10 1556-1 RabMAb 100µl, ICC Human $250 TCF-1 (Alpha) 2091-1 RabMAb 100µl, IHC, ICC, FC Human $250 TCF-3 2598-1 RabMAb 100µl, FC Human $250 TCF-4 2114-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 New TCP1 Alpha 2854-1 RabMAb 100µl, IHC, ICC, IP Human $250 New TCP1 Beta 2855-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 New TCP1 Beta 2883-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 TdT 2481-1 RabMAb 100µl, ICC Human $250 TdT 2576-1 RabMAb 100µl, FC Human $250 TEC 1618-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 TGIF (C-term) 1916-1 RabMAb 100µl, IP Human $250 Thiophosphate Ester 2686-1 RabMAb 50µl Human, Mouse, Rat $305 Thymidine Kinase 1 2563-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Thymidine Kinase 1 2664-1 RabMAb 100µl, ICC, FC Human $250 Thyroglobulin 2653-1 RabMAb 100µl, IHC, IP Human $250 IHC on human papillary thyroid carcinoma Thyroglobulin (TG) is a dimeric glycoprotein specific to the thyroid gland which belongs to the type-b carboxylesterase/lipase family. It is the precursor of the iodinated thyroid hormones triiodothyronine (T3) and thyroxine (T4). Variations in TG are associated with susceptibility to autoimmune thyroid disease type 3, and defective or impaired TG synthesis usually results in congenital goitrous hypothyroidism, virtual absence of TG in thyroid tissue, and the presence of an elevated concentration of iodoalbumin. The final result of these abnormalities is a decreased rate of T3 and T4 synthesis. Specificity: A synthetic peptide corresponding to residues in human Thyroglobulin was used as an immunogen. on human thyroid lysate Thyroglobulin 2654-1 RabMAb 100µl, IP Human $250 TIMP-1 2109-1 RabMAb 100µl Human $210 TIRAP 1892-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 TLR-1 (Extracellular) 2314-1 RabMAb 100µl, IP Human $250 TLR-2 (Extracellular) 2323-1 RabMAb 100µl, ICC Human $250 New TMPRSS2 2770-1 RabMAb 100µl, IHC, ICC, FC Human $250 52 53

TNF (Alpha) 1790-1 RabPAb 100µl Human $210 TNF (Alpha) 1836-1 RabMAb 100µl Hu $210 TTF1 2044-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 New TTF1 2801-1 RabMAb 100µl, IHC, ICC, IP Human $250 TNF (Beta) 1838-1 RabMAb 100µl Human $210 TNFAIP3 2644-1 RabMAb 100µl, IHC, ICC, FC Human $250 TNFR1 2348-1 RabMAb 100µl, FC Human $250 New TNNT2 2706-1 RabMAb 100µl Human, Mouse, Rat $210 TOPK - See PBK Topoisomerase II (Alpha) 1826-1 RabMAb 100µl, IHC, IP Human, Mouse $250 IHC on human breast carcinoma IHC on human stomach Trefoil factor 1 (TFF1), a member of the trefoil factor family, is a stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. It belongs to a family of abundant GI3 peptides with a distinct 3-loop structure formed by a highly conserved motif of cysteine disulfide bonds, which confer them with luminal stability. In breast cancer, its regulation by estrogen is an indicator of estrogen receptor (ER) functionality. Specificity: A synthetic peptide corresponding to residues in human TFF1 was used as an immunogen. Topoisomerase II Phospho (Alpha, ps1106) Topoisomerase II Phospho (Alpha, pt1343) 2405-1 RabMAb 100µl, IHC, ICC Human $285 1871-1 RabMAb 100µl, IHC, ICC Human $285 New TORC1 2745-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 TORC3 2670-1 RabMAb 100µl, IHC, IP Human $250 Torsin A 2439-1 RabMAb 100µl, IP Human, Mouse, Rat $250 Tpl2 1855-1 RabMAb 100µl Human $210 TPPP 2633-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 New TPPP 2775-1 RabMAb 100µl, IHC, ICC, IP Human $250 TRADD 2663-1 RabMAb 100µl Human $250 TRAF3 2107-1 RabMAb 100µl, IHC, ICC, FC Human $250 TRAF6 1660-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 TRAF6 (C-term) 1669-1 RabMAb 100µl, ICC Human, Mouse, Rat $250 New TRF2 2908-1 RabMAb 100µl, FC, IP Human $250 Transcription factor PU.1 2479-1 RabMAb 100µl, IHC, ICC, IP Human $250 Transcription factor PU.1 2480-1 RabMAb 100µl, IHC Human $250 Transthyretin 2434-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 TRAP cleavage (CD40 Ligand) 1845-1 RabMAb 100µl, FC Human, Mouse, Rat $250 TRIB3 2488-1 RabMAb 100µl, IP Human $250 TRIB3 2501-1 RabMAb 100µl Human, Mouse, Rat $250 Trk 2205-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 TrkA 2244-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Trk B Phospho (py817) 2149-1 RabMAb 100µl, ICC, IP Human, Rat $285 Troponin 1 1875-1 RabMAb 100µl, IHC, IP Human $250 Troponin T Type 2 2649-1 RabMAb 100µl, IHC, IP Human $250 Troponin T type 2 (TNNT2) is a cardiac troponin T isoform expressed in the human heart, that is essential for calcium-regulated myofibrillar ATPase activity. Troponin T (TnT) anchors the complex to the thin filaments in vertebrate striated muscle, and functions as a regulatory system for muscle contraction in response to changes to intracellular calcium ion concentration. All subunits of Tnnt2 have been associated with hypertrophic cardiomyopathy (HCM). New TTF3 2044-1 RabMAb 100µl, IHC, ICC, IP Human $250 Tuberin 1824-1 RabMAb 100µl, IHC, FC, IP Human $250 Tuberin Phospho (ps939) 1823-1 RabMAb 100µl, ICC Human, Mouse, Rat $285 Tuberin - See TSC2 Tubulin (Alpha) 1878-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 New Tubulin (Alpha) 2871-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Tubulin (Beta) 1799-1 RabPAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Tubulin (Beta) 1879-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Tubulin (Beta, Class III, C-term) 1967-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Tubulin (Beta, Class III, C-term) 2276-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 Tubulin Phospho (Alpha, py272) 2243-1 RabMAb 100µl, ICC Human $285 Tyk2 1841-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Tyrosinase (TYR) 2038-1 RabMAb 100µl, IHC, FC, IP Human, Mouse, Rat $250 Tyrosine 3-Hydroxylase 2129-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 Tyrosine 3-Hydroxylase 2266-1 RabMAb 100µl, ICC, FC Human, Mouse, Rat $250 U UBC-1 1829-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 U UBC-1 2339-1 RabMAb 100µl, ICC, IP Human $250 UBC-9 2426-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 UBF 2406-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse $250 Ubiquitin (C-term) 1646-1 RabMAb 100µl, IHC Human, Mouse, Rat $250 V VAMP8 2379-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 V Vav 1746-1 RabMAb 100µl, ICC, IP Human, Rat $250 Vav Phospho (py174) 2133-1 RabMAb 100µl, ICC Human $285 Vav2 1993-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse, Rat $250 Vav3 1771-1 RabPAb 100µl, IHC, ICC, FC, IP Human, Mouse $250 Vav3 (Pan) 1820-1 RabMAb 100µl, FC, IP Human, Mouse $250 VE-Cadherin 2465-1 RabMAb 100µl, FC, IP Human $250 VEGF (C-term) 1909-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 IHC on human cardiac muscle Specificity: A synthetic peptide corresponding to residues in human Troponin T type 2 was used as an immunogen. VEGFR1 (N-term) 1303-1 RabMAb 100µl, IHC, ICC, IP Human, Mouse $250 VEGFR2 2296-1 RabMAb 100µl, IP Human $250 TRPC1 1942-1 RabMAb 100µl, FC, IP Human, Rat $250 New Vimentin 2862-1 RabMAb 100µl, IHC, ICC Human $250 Tryptophan Hydroxylase 1 (TPH1) 1915-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 New Tryptophany-tRNA sythase 2756-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 TSC1 1744-1 RabMAb 100µl, IHC Human $250 TSC2 (C-term) 1613-1 RabMAb 100µl, IHC, FC Human, Mouse, Rat $250 TSK - See EMTK 54 55

Vimentin 4211-1 RabMAb 100µl, IHC, IP Human, Mouse, Rat $205 New Vimentin 2707-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 ICC on HeLa IHC on gastric adenocarcinoma Vimentin is the most common member of intermediate filament (IF) family and one of the main components in cytoskeleton structure. It is expressed during cell development and differentiation in variety of mescencymal cells and cell types derived from mesoderm. Vimentin is essential in the role of cell integrity and cytoskeletal stability. PAK phosphorylates at Ser25, Ser38, Ser50, Ser65 and Ser72 which induces Vimentin specific reorganization. Specificity: A synthetic acetylated peptide corresponding to C-terminus of human Vimentin was used as an immunogen. Vimentin Phospho (ps38) 1866-1 RabMAb 100µl Human, Mouse, Rat $285 Vimentin Phospho (ps72) 1868-1 RabMAb 100µl, IP Human, Mouse, Rat $285 Vimentin Phospho (ps82) 1867-1 RabMAb 100µl Human, Mouse, Rat $285 Vitamin D-binding protein 2470-1 RabMAb 100µl, ICC, FC Human $250 Vitamin D-binding protein 2471-1 RabMAb 100µl, IHC, ICC, FC Human $250 Vitronectin 1730-1 RabMAb 100µl, IHC, IP Human $250 Vitronectin 1783-1 RabMAb 100µl, IHC, ICC Human, Mouse, Rat $250 VLA (Alpha 4) 2101-1 RabMAb 100µl, IHC, ICC, IP Human $250 W WASP 2304-1 RabMAb 100µl, ICC, FC, IP Human, Mouse, Rat $250 W WASP 2422-1 RabMAb 100µl, IHC, ICC Human $250 Support Products Secondary Antibodies, Controls, Cell Lysis Buffer Product Name Catalog # Quantity Applications Secondary Antibodies Species Reactivity Goat Anti-Rabbit IgG (H+L) - HRP 3053-1 2ml, IP-Blot, ELISA Rabbit IgG $195 Goat Anti-Rabbit IgG Polymer HRP 3051-1 5ml IHC Rabbit IgG Contact us for pricing Rabbit IgG Control ISO-XXXX 100µl FC, IHC - $89 Control Cell Lysates HeLa 3710-1 100µg - - $105 Jurkat 3720-1 100µg - - $105 Jurkat + Camptothecin 3721-1 100µg - - $155 MCF-7 3730-1 100µg - - $155 K562 3740-1 100µg - - $105 Daudi 3750-1 100µg - - $105 A431 3760-1 100µg - - $105 A431 + EGF 3761-1 100µg - - $155 Other Support Products Blocking Peptides Please Inquire 100µg - - $89 Cell Lysis Buffer (non-denaturing) 3500-1 15ml - - $75 Price WASP 2422-1 RabMAb 100µl, IHC, ICC Human $250 New Wilm s Tumor 2797-1 RabMAb 100µl, IHC Human $250 IHC human fetal kidney IHC on Wilm s Tumor Wilm s Tumor (WT) is a 55 kda protein thought to play a major role in various cancers and developmental disorders, commonly kidney tumors and glomerular diseases. WT is a zinc finger transcription factor that is mutated in Wilm s tumors and highly expressed in a wide variety of other malignancies. WT1 consists of two major isoforms; WT1 (-KTS), a transcription factor, and WT1 (+KTS). Specificity: A recombinant protein corresponding to the N-terminus of human WT was used as an immunogen. WSTF 2033-1 RabMAb 100µl, IHC, ICC, FC Human, Mouse, Rat $250 Y YAP65 2060-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 Y YAP65 Phospho (ps127) 2209-1 RabMAb 100µl, IHC Human $285 YBOX1 / YB-1 2387-1 RabMAb 100µl, IP, FC Human $250 YBOX1 / YB-1 (C-term) 2397-1 RabMAb 100µl, IHC, ICC, FC, IP Human, Mouse, Rat $250 Z ZAP-70 1267-1 RabMAb 100µl, FC, IP Human, Mouse, Rat $250 Z New ZAP-70 2869-1 RabMAb 100µl, IHC, ICC, IP Human $250 ZAP-70 (C-term) 1491-1 RabMAb 100µl, IHC, ICC, FC, IP Human $250 ZAP-70 Phospho (py292) 2535-1 RabMAb 100µl, IHC, ICC, FC, IP Human $285 ZAP-70 Phospho (py492) 2215-1 RabMAb 100µl, IP Human $285 Antibody Sampler Packs For recommended Protocols and FAQs - See Support Page @ www.epitomics.com We have specifically selected several of our more popular antibodies into sampler kits for customers to evaluate specific pathways. 40µl of each antibody are provided in each kit. Product Name Catalog # Quantity Applications Species Reactivity Apoptosis Sampler Kit 5000-1 40µl per vial, IHC, ICC, IP, FC Human, Mouse, Rat $595 Bcl-2 Family Sampler Kit 5001-1 40µl per vial, IHC, ICC, IP, FC Human, Mouse, Rat $595 Cytoskeletal Sampler Kit 5002-1 40µl per vial, IHC, ICC, IP, FC Human, Mouse, Rat $595 Translation Control Sampler Kit 5003-1 40µl per vial, IHC, ICC, IP, FC Human, Mouse, Rat $595 Cell Survival Sampler Kit 5004-1 40µl per vial, IHC, ICC, IP, FC Human, Mouse, Rat $595 Akt Substrates Sampler Kit 5005-1 40µl per vial, IHC, ICC, IP, FC Human, Mouse, Rat $595 MMP Family 5006-1 40µl per vial, IHC, ICC, IP, FC Human, Mouse, Rat $595 PAK Family 5007-1 40µl per vial, IHC, ICC, IP, FC Human, Mouse, Rat $295 Price 56 57

Support Products IgG Specific Rabbit Monoclonal Antibodies Monoclonal antibodies specific to various IgG. For use in immunoassays such as ELISA to detect IgG molecules. Anti-Human IgG Antibodies Product Name Cat # Amount Clone ID IgG 1κ IgG 1λ IgG 2k IgG 2λ IgG 3k IgG 3λ IgG 4k IgG 4λ IgA IgM Fc F(ab )2 Species Reactivity IgG Pan 3010-1 250μg H169-1 + + NT + + + + + - - + - Human $225 IgG 1 (H+L) 3012-1 250μg H26-10 NT + NT - - - NT NT - - + + Human $250 Price Kits - ELISA New EpiQ ELISA Kits Featuring RabMAb Technology Enjoy the benefits of High Affinity and Specificity of Rabbit Monoclonal Antibodies in all-inone ELISA kit Easy and consistent sandwich ELISA detection of Total and Phosholyated targets such as c-jun and ZAP-70 Kappa Light Chain Specific 3013-1 100μg H19-5 + - + - + - + - + + - + Human $225 ELISA kits for high quality detection of other regulatory proteins - Histones, PBK Anti-Mouse IgG Antibodies New Epitomics EpiQ ELISA Kits offer high quality, accurate assays that detect important regulatory proteins and small molecules in one easy-to-use kit. Product Name Cat # Amount Clone ID IgG 1 IgG 2a IgG 2b IgG 3 IgA IgM Species Reactivity Price With the benefits of Epitomics patented Rabbit Monoclonal Technology to capture and detect, EpiQ ELISA kits offers higher specificity and sensitivity compared to traditional ELISA methods. IgG Pan 3020-1 250μg M111-2 + + + + - - Mouse, Rat $250 IgG 1 3021-1 250μg MIgG51-4 + NT - - - - Mouse, $250 Fig 1. Detection of total and phosphorylated c-jun from Anisomycin treated 3T3 cell lysates via c-jun Dual Detection Kit (6116-1) and Western Blot. IgG 1 3022-1 250μg M108-10 + - - - - - Mouse $250 IgG 2b 3023-1 250μg M52-8 - - + - - - Mouse, Human $250 IgG 1 IgG 2a 3024-1 250μg M204-3 + + - + - - Mouse, Rat $250 IgG 3 IgG 1 3025-1 250μg M87-3 + + + - - - Mouse, Rat $250 IgG 2 Target Protein Detection Ab Streptavidin Biotin HRP TMB Substrate Fig 2. This assay employs the sandwich enzyme immunoassay technique that detects endogenous and/or phosphorylated levels of protein. IgG 2a 3026-1 250μg M180-5 - + - - - - Mouse $250 Capture Ab Anti-Rat, Anti-Chicken, Anti-Sheep Antibodies Coated Microwells Product Name Rat IgG Rat IgG Cat # Amount Clone ID Rat IgG Mouse IgG Chicken IgY Sheep IgG Species Reactivity 3030-1 250μg R18-2 + - NT NT Rat $250 3031-1 250μg R69-8 + + NT NT Rat, Mouse $250 Chicken IgG (IgY) 3035-1 250μg Ch.44-2 NT NT + NT Chicken $250 Sheep IgG 3036-1 250μg Sh.76-10 NT NT NT + Sheep $250 LEGEND : + (Positive), - (Negative), NT (Not Tested) All tests were based on ELISA testings Price ELISA Kit Catalog # Type Species Reactivity Price EpiQ ELISA Kits New Akt (Human Specific) 6119-1 Sandwich ELISA (96 Reactions) Human $450 c-jun 6111-1 Sandwich ELISA (96 Reactions) Human, Mouse, Rat $450 c-jun Phospho (pt91/93) 6115-1 Sandwich ELISA (96 Reactions) Human, Mouse, Rat $450 Histone H2B Acetyl (K5) 6110-1 Sandwich ELISA (96 Reactions) Human, Mouse, Rat $450 MIP-1 beta 6118-1 Sandwich ELISA (96 Reactions) Human, Mouse, Rat $450 PBK 6112-1 Sandwich ELISA (96 Reactions) Human, Mouse, Rat $450 ZAP-70 Total 6114-1 Sandwich ELISA (96 Reactions) Human, Mouse, Rat $450 ZAP-70 Phospho (py492) 6113-1 Sandwich ELISA (96 Reactions) Human, Mouse, Rat $450 Dual EpiQ ELISA Kits c-jun Dual Detection Total & Phospho (pt91/93) Zap-70 Dual Detection Total & Phospho (py492) 6116-1 Dual Sandwich ELISA (96 Reactions) Human, Mouse, Rat $495 6117-1 Dual Sandwich ELISA (96 Reactions) Human, Mouse, Rat $495 58 59

Kits - ELISA (PEG) EpiQ PEG ELISA Kit Convenient Detection of PEGylated Molecules Kits - IHC Single & Dual IHC Kits Quantitate PEGylated molecules in plasma, serum or cell culture medium Highly sensitive assay accurately determines concentration of PEGylated molecules (ng/ml) Carry out Pharmacokinetic studies OD450 2.5 2.0 1.5 1.0 0.5 BSA-PEG ADI-PEG Mouse IgG-PEG Enjoy the benefits of High Affinity and Specificity of Rabbit Monoclonal Antibodies in all-in-one IHC kit All kits utilizes Polymer based secondary detection system for strong IHC staining Perform High Quality double staining with monoclonal antibodies on same tissue section EpiQ ELISA Kits helps you to achieve more consistent and accurate results in less time -- allowing you to focus on your result. Epitomics EpiQ PEG ELISA Kit offers a high quality, accurate assay that quantifies PEGylated molecules (ng/ml) in one easy-to-use kit. Polyethylene glycol (PEG) is an O-CH2-CH2 polymer, which is water-soluble, nontoxic, nonantigenic, and biocompatible. Covalent conjugation of PEG to therapeutic proteins increases their in vivo stability by protecting the protein from degradation, masking its immunogenic sites and reducing clearance. Qualitative and quantitative analysis of PEGylated molecules is important for both drug development and clinical applications. Therefore, this kit is developed to determine levels of PEGylated molecules in samples such as serum via ELISA. Anti-PEG RabMAb + H S PEG labeled HRP (H) PEG labeled Sample (S) S H S Competition TMB Fig 1. Competition between PEG labeled HRP (H) and PEG labeled sample (S) in PEG ELISA assay S H HRP (H) Activation S OD450 0.0 0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 1 5 10 25 50 75 100 ng/ml Fig 2a Competition between PEGylated molecules and HRP-mPEG IgG-PEG (ng/ml) Mouse IgG-PEG y = 1.11x -0.34 2 R = 0.93 0.0 0 500 1000 1500 2000 2500 ng/ml Fig 2b Pharmacokinetics Experiment using the fitted curve y=1.11x -0.34 1500 1200 900 600 300 Control Rat 1 0 0 10 20 30 40 50 time (hours) Fig 2c Pharmacokinetics Experiment: Plot of PEGylated IgG concentration over time (hours) For more info - visit IHC Portal on-line @ www.epitomics.com Epitomics IHC kits are a complete ready-to-use IHC staining system, designed to be utilized with Epitomics primary Rabbit Monoclonal antibodies (RabMAb ) for detection of specific target antigens in tissue samples. When combined with an appropriate RabMAb the IHC Staining Kit combines the superior antigen recognition of rabbit monoclonals antibodies with novel polymer based enzyme labeled secondary antibody which provides a stronger and cleaner signal than comparable non-polymer based secondary antibodies. For double IHC staining, pair any suitable RabMAb with a Mouse MAb for a high quality double staining using Epitomics Dual Staining IHC Kit. IHC Kit Catalog # Kit Type Species Reactivity Price Single Staining Kit Ace IHC Detection Kit 4002-1 Single Polymer Detection (DAB, 50 slides) Human, Mouse, Rat Contact us for pricing Dual Staining Kit Tandem IHC Staining Kit 4000-1 Double Polymer Detection (FastRed, DAB, 50 slides) Human, Mouse, Rat Contact us for pricing Kit Contents: 1. Antigen Retrieval solution (1X) 2. Peroxidase Block solution 3. Blocking solution 4. Primary antibody diluent 5. Negative control rabbit IgG (1X) 6. *Secondary anti-rabbit (HRP) and/or anti-mouse (AP) 7. *DAB or Fast Red tablets *Depending on the kit ELISA Kit Catalog # Type Species Reactivity Price PEG ELISA Kit 6100-1 Competitive ELISA (96 Reactions) Human, Mouse, Rat $525 Learn more about Epitomics ELISA Kits @ www.epitomics.com Fig 1. HSP73 staining on human breast carcinoma using Ace IHC detection kit. Fig 2. Cytokeratin 8 (FastRed) and Ki-67 (DAB) on urinary bladder cancer tissue using Tandem IHC staining kit. 60 61

Kits - Purification EpiMAX Purification Kits One Stop Antibody Purification System All-In-One Antibody Purification Kit Quick and Simple Peptide/Protein Immobilization Maximum Antibody Yield in Less Time Versatile Gel Matrix with High Binding Capacity and Stability EpiMAX Affinity Purification kit is a complete antibody purification solution for quick and easy purification of ultra pure antibodies. EpiMAX Affinity Purification kit utilizes Epitomics ASA (Activated Serial-A) Matrix Gel Technology in which the activated gel matrix in the kit can form highly stable covalent immobilization with any SH- or NH3- containing peptide/protein in a few simple steps (Figure 1). Highly verstile and stable, ASA Matrix Gel provides multiple benefits, from increased antibody binding capacity (Figure 2) to enhanced target antibody recovery (with the typical antibody purity being in the range of >95%) (Figure 3) compared to traditional peptide purification methods. Fig 1. Reaction scheme for coupling of peptde to ASA gel matrix mg/ml of gel EpiMAX Vendor A 20 15 10 5 0 Binding Capacity 15.7 5.3 3.5 2.1 Min Max % Recovery 30 25 20 15 10 5 0 Antibody Recovery Efficiency 6.0% 1.0% Min EpiMAX 20% 18% Max Vendor A Fig 2. A comparison of min and max Antibody Binding Capacity (mg/ml of gel) between Epi- MAX TM and Vendor A s Purification Kit Fig 3. A comparison of minimum and maximum target antibody recovery (%) between EpiMAX and Vendor A. ELISA Kit Catalog # Type Price EpiMAX Purification Kit 6000-1 Antibody Purification (5 Antibodies) $395 For More EpiMAX Purification Kit Comparison Data and Benefits - Please visit www.epitomics.com 62

Custom Services Rabbit Monoclonal Antibody Development In the last six years, Epitomics has developed high quality custom Rabbit Monoclonal Antibodies using our patented rabbit fusion partner cell line. With several advantages over traditional monoclonal services (Table 1), we have provided services to customers in all the major pharmaceutical, biotech and academic institutions. The standard service as outlined at the bottom of the page is divided into three distinct phases (Table 2). Customers are involved in each phase to ensure the development of a high quality monoclonal antibody suited to their specifications. For More Info on Custom Service - Please Visit www.epitomics.com under Service Traditional Mouse Monoclonal Epitomics Rabbit Monoclonals (RabMAbs ) Antigen Recognition Limited Immune Response Small molecules peptides often non-immunogenic Usual recognition of 1-2 epitopes on a particular antigen Excellent response to broader range of antigens (small molecules, peptides, phospholaytion site) Possible to generate antibodies to rodent proteins Recognition of multiple epitopes (2+) on an antigen. Affinities Typical binding affinity at 10-7 10-8 kda Rare to reaches maximum binding affinity at 10-9 kda Provides 1000 times higher binding affinity compared to Mouse Monoclonal. Minimum - 10-9 10-10 kda Maximum - 10-12 kda Specificity Medium to High High Applications, IHC, ICC, IP, FC, ELISA. Requires antigen retrieval pretreatment (Heat or Enzyme) on paraffin embedded tissues sections. Not suitable to use for staining rodents tissues - higher background., IHC, ICC, IP, FC, ELISA. Antigen retrieval pretreatment is not necessary on paraffin embedded tissue sections. Especially useful for working with rodents tissues. Lower background in tissue staining. Humanization Possible but low homology to human germline sequence. An excellent starting point for humanization: Higher homology to human germline sequence. Table 1. Advantages of rabbit monoclonal service over mouse monoclonal service. Contact us to discuss your custom antibody needs or schedule a presentation about our technology and services. Phone: 877-7RABMAB (772-2622) (Toll Free in North America) 650-583-6688 Email : service@epitomics.com Online Custom Service Request Form Available @ www.epitomics.com Table 2. Overview of Epitomics Rabbit Monoclonal Service.

Rabbit Monoclonal Antibodies - Spring 2010 The R abbit M ono clonal Company 863 Mitten Rd. Suite 103 Burlingame, CA 94010 Inside: Actin Adducin AFP AIF Akt1 Aldh1A1 Alk Amphipysin AMPK APP Androgen Receptor Apaf1 APC Apo E ARF1 Arrestin 1 ASK1 Asparagine Synthetase ATF2 Atg7 ATM ATP-citrate lyase Aurora A Aurora B Aurora C B7-1 Bad Bag-1 Bak Bax Bcl-2 Bcl-6 Bcl-10 Bcl-x Bcr BDNF Beclin-1 Arrestin Catenin Synuclein Tubulin Bid Bim BIR3 BLNK Myc Btk C/EBP C-Abl CAD Cadherin Calcitonin Caldesmon Over Calponin 1600 Calretinin Rabbit CaMKI Monoclonal Casein Kinase Antibodies Caspases (RabMAbs Catalase Catenin ) and related Caveolin-1 products Cbl CCL4 CCR2 CCR7 CCR9 CD11a CD11b CD20 CD22 CD3 CD5 CD8 CD34 CD40 Ligand CD45 CD80 CD86 Cdc2 Cdc25c Cdk2 Cdk5 CENP-A Chk1 Chk2 Chromogranin New Antibodies A c-jun Cytokeratin and Kits 8/18 - BioActive C-myc cortactin Antibodies, Cox2 ELISA c-product Kits Creb Crk CrkL Cyclin A2 Cyclin B1 Cyclin D1 Cyclin E1 Cyclin Rabbit E2 Cytochrome Monoclonal C Cytokeratin Vs. Mouse 4 Cytokeartin Monoclonal 5 Cytokeratin Comparison 6 Cytokeratin 14 Cytokeratin 29 Cytokeratin 20 DAP-1 DAPK2 DAPK3 Custom DARPP-32 Antibody Daxx Service Desmin Diablo Dsh-3 Dynamin-1 Dystroglycan E-cadherin eef2 EGFR eif2a eif4e eif5a Elk1 EMSY EMTK Endo G EphA3 Ep-CAM Estrongen Receptor ErbB Erk1 Erk2 Erk3 Estrongen Related Receptor Etk Ezh1 Ezh2 Ezrin FADD FAK FAK2 Fc gamma RIIb Fer FGFR-1 Fibronectin FKHR Flotillin-1 Flt3-L FOXO3a FRAP Fyn Gab1 Gab2 Synuclein GAP43 GCDFP15 Gelsolin GFAP GFP GluR1 GluR2 GluR3 Glutathione Glycodelin Glycogen Synthase GM130 GOS-28 GRB2 GRK2 GRP1 GSK3 Gstk1 Hamartin Heme Oxygenase 1 Her2 Her3 Her4 HIAP-1 HIF-1 Histone H2 Histone H3 Histone H4 HIV-p24 hnrnpk HoxB4 HPK1 H-Ras HSD17B1 HSF1 c-jun HSF4 HSP27 HSP60 HSP70 HSP73 HSP90 htert HtrA2 Huntingtin ICAM-1 IDO IFN Alpha IFN Gamma IGBP1 IKK Alpha IKK Beta IL-1 IL-1R IL-3R IL-4 IL-6 IL-10 ILK IHH INSR Integrin IRAK-3 IRAK-4 IRS-1 IRS-2 IRS-3 ITAM ITGB1 ITGB2 ITK Jak2 Jak3 JAM1 JNK2 JNK3 KDR Ki-67 Kv4.2 LBR LAT LCAT Lck LDH-A LDH-B LDH-C LDL Receptor LEF-1 LFA-1a Lyn MAG MALT1 MAPILC3A MAPKAP Kinase-2 TNF Beta MARK3 MART1 MBP Mcl-1 MCM7 MCP-1 M-CSF MEF2A MEK1 MEK2 MEKK2 MEKK3 MEKK4 MEKK5 MerTK Met MHC Class I Midkine MIP-1 MKK3 MKK4 MKK5 MKK6 MKK7 MKP3 MLCK MLK3 MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-11 ER Alpha MMP-13 MMP-14 MMP-17 MMP-20 MMP-21 MMP-26 Mo25 Moesin SMAD1 MSK1 Mst1 Mst2 Mst3 Mst4 mtor MUC1 Musashi-1 Her2 MYPT1 MYPT2 NAK NCK NF-66 NF-L NF-KappaB NGF Nibrin inos Noggin Notch-1 NPM Nrf2 Oct-2 Op18 p16 P21 P27 p38 p40 p44 p53 p58 p70 p73 p80 p120 p130 PAEP PAK1 PAK2 PAK3 PAK4 Parkin PARP-1 PARP-2 Paxillin PDGFR PDK1 PDK2 PI3- Kinase p85 subunit PI3-Kinase p110 subunit Pin1 PKA PKC PKR PLAP PLC Beta II PLC Gamma II Plectin Pol II PEG Pou Domain Protein 3A PP1 PP2A PP2B PRA1 PRC1 Presenilin Presenilin 2 Prion Prtein PRK2 PR PSA PTEN PTP1B PUMA Pyk2 Radixin Raf-1 RAIDD RanBP9 RANTES Rap1 CK 18 Raptor RAR Ras RasGap Rb Rb2 RelB Rho EGFR Ron Rsk1 Rsk2 Rsk3 CDX2 S100 Beta SCF SEK Serum Amyloid P-compoent SGK SHC1 SHH SHP-1 SHP-2 SIRT1 SIRT2 Smac Smad1 Smad2 Smad3 Smad4 Smad5 Smurf2 SOD1 SR-B1 Scavenge Receptor Src Stat-1 Stat-2 Stat-3 Stat-5 Stat- 6 Stathmin SUMO-1 SoF Syk Synapsin I Synaptophysin Synip Synuclein Alpha Synuclein Beta TAB1 Tau TBK1 TC10 TCF-1 TCF-4 TEC TGIF TIMP-1 TIRAP TNF Alpha TNF Beta Topo II Alpha Tp12 TRAP3 TRAP6 TRAP cleavage TrkB Phospho Troponin 1 TRPC1 TPH1 TSC1 E-Cadherin TSC2 Tubulin Alpha Tubulin Beta Tyk2 Tyrosinase Tyrosine 3-Hydroxylase UBC-1 Ubiquitin Vav Vav2 Vav3 VEGF VEGFR-1 VEGFR-2 Vimentin Vitronectin VLA Alpha 4 WSTF YAP65 ZAP-70 www.epitomics.com Contact Epitomics: PH: 877-772-2622 650-583-6688 FAX: 650-583-6680 info@epitomics.com orders@epitomics.com service@epitomics.com Copyright 2002-2010, Epitomics, Inc. All rights reserved. Epitomics and RabMAb are registered trademarks of Epitomics, Inc. SP10